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Product Details
PA5-65908
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human ATMIN. Recombinant protein control fragment (Product #RP-106587).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2662101
Product Specific Information
Immunogen sequence: SVSELSRAVRT NILCTVRGCG KILPNSPALN MHLVKSHRLQ DGIVNPTIRK DLKTGPKFYC CPIEGCPRGP ERPFSQFSLV KQHFMKMHAE KKHKC
Highest antigen sequence identity to the following orthologs - mouse 95%, rat 95%.
Target Information
The ATM/ATR-substrate CHK2-interacting zinc finger protein (ATMIN), also known as ASCIZ, forms DNA damage-induced nuclear foci that contain the DNA repair protein Rad51. ATMIN is also thought to be involved in embryonic development, as an absence of ATMIN causes late-embryonic lethality in mice with a range of organ development defects. It also activates the transcription DYNLL1, a light chain of the dynein motor complex and sequence-specific regulator of protein dimerization of numerous targets. DYNLL1 can bind to and inhibit the transcription activation domain of ATMIN, forming a simple dynamic feedback loop for DYNLL1 expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ASCIZ; ATM INteracting protein; ATM interactor; ATM/ATR-substrate CHEK2-interacting zinc finger protein; ATM/ATR-substrate CHK2-interacting zinc finger protein; ATM/ATR-Substrate Chk2-Interacting Zn++-finger protein; Zinc finger protein 822
Gene Aliases: ASCIZ; ATMIN; KIAA0431; ZNF822
UniProt ID: (Human) O43313
Entrez Gene ID: (Human) 23300
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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