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Application
FIGURE: 1 / 3
ATP11B Antibody (PA5-20996) in ICC/IF
Immunocytochemistry of ATP11B in K562 cells with ATP11B Polyclonal Antibody (Product # PA5-20996) at 10 µg/mL.
Product Details
PA5-20996
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 19 amino acid peptide near the amino terminus of human ATP11B.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11152699
Product Specific Information
A suggested positive control is K562 cell lysate.
PA5-20996 can be used with blocking peptide PEP-1110.
Target Information
ATP11B is a widely expressed integral membrane ATPase and is thought to drive the transport of phospholipids across membranes. It has been suggested that ATP11B is hormonally regulated and plays a role in the subnuclear trafficking of transcription factors with RING motifs. While the exact molecule ATP11B transports is unknown, increased mRNA expression of the homologous ATP11A has been observed in cells resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs), suggesting that ATP11B may also play a role in cell survival under harsh conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATPase class VI type 11B; ATPase IR; ATPase, class VI, type 11B; P4-ATPase flippase complex alpha subunit ATP11B; Phospholipid-transporting ATPase IF; probable phospholipid-transporting ATPase IF; TIEG; TIEG1; truncated ATPase 11B protein
Gene Aliases: 1110019I14Rik; ATP11B; ATPIF; ATPIR; KIAA0956; mKIAA0956
UniProt ID: (Human) Q9Y2G3, (Mouse) Q6DFW5
Entrez Gene ID: (Human) 23200, (Mouse) 76295
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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