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            • Primary Antibodies ›
            • ATP13A2 Antibodies

            Invitrogen

            ATP13A2 Polyclonal Antibody, HRP

            View all (13) ATP13A2 antibodies
            Datasheet
            Protocols
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            Datasheet
            Protocols
            Questions & Answers

            Cite ATP13A2 Polyclonal Antibody, HRP

            Product Details

            PA5-22852

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            2 µg/mL
            -

            Immunohistochemistry (IHC)

            10-20 µg/mL
            -
            Product Specifications

            Species Reactivity

            Human, Mouse

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            A synthetic peptide within the internal region of residues 200-300 of the human ATP13A2 protein.
            View immunogen

            Conjugate

            HRP

            Form

            Liquid

            Concentration

            0.75 mg/mL

            Purification

            Antigen affinity chromatography

            Storage buffer

            PBS

            Contains

            no preservative

            Storage conditions

            4°C, store in dark

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_11153958

            Product Specific Information

            Suggested positive control: human and mouse brain membrane prep lysate.

            Target Information

            Neurodegenerative disorders such as Parkinson and Alzheimer disease cause motor and cognitive dysfunction and belong to a heterogeneous group of common and disabling disorders. ATP13A2, otherwise known as PARK9, is a neuronal P-type ATPase gene underlying an autosomal recessive form of early-onset parkinsonism with pyramidal degeneration and dementia. ATP13A2 protein is located in the membrane of these lysosomes and is formed most strongly in the brain, especially in the substantia nigra, a brain region which is known to play a central role in Parkinson's disease.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

            Have you cited this product in a publication?
            Let us know so we can reference it here.
            Cite this product

            Bioinformatics

            Protein Aliases: AT132 antibody; ATPase type 13A2; HSA9947 antibody; Polyamine-transporting ATPase 13A2; probable cation-transporting ATPase 13A2; putative ATPase; RP1-37C10.4

            View more View less

            Gene Aliases: 1110012E06Rik; AA589443; ATP13A2; CLN12; HSA9947; KRPPD; PARK9

            View more View less

            UniProt ID: (Human) Q9NQ11, (Mouse) Q9CTG6

            View more View less

            Entrez Gene ID: (Human) 23400, (Mouse) 74772

            View more View less

            Function(s)

            protein binding ATP binding zinc ion binding ATPase activity cation-transporting ATPase activity manganese ion binding phosphatidic acid binding phosphatidylinositol-3,5-bisphosphate binding cupric ion binding nucleotide binding hydrolase activity metal ion binding

            Process(es)

            cellular calcium ion homeostasis cellular iron ion homeostasis cellular zinc ion homeostasis regulation of mitochondrion organization regulation of macroautophagy regulation of autophagosome size cellular cation homeostasis regulation of intracellular protein transport ion transmembrane transport cellular response to oxidative stress protein autophosphorylation positive regulation of protein secretion regulation of endopeptidase activity zinc ion homeostasis cellular response to manganese ion cellular response to zinc ion cation transmembrane transport negative regulation of neuron death regulation of mitophagy positive regulation of exosomal secretion regulation of chaperone-mediated autophagy autophagosome organization polyamine import regulation of lysosomal protein catabolic process negative regulation of lysosomal protein catabolic process peptidyl-aspartic acid autophosphorylation cation transport
            It has to be done as per old AB suggested Products section.
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            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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