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            • Primary Antibodies ›
            • ATP1B1 Antibodies

            Invitrogen

            ATP1B1 Polyclonal Antibody

            Advanced Verification
            View all (12) ATP1B1 antibodies

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            Datasheet
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            Catalog # PA5-82474
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            Cite ATP1B1 Polyclonal Antibody

            • Antibody Testing Data (2)
            • Advanced Verification (2)
            Application
            ATP1B1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Group 53 Created with Sketch.

            FIGURE: 1 / 4

            ATP1B1 Antibody (PA5-82474) in IHC (P)

            Immunohistochemical analysis of ATP1B1 in human lymph node using ATP1B1 Polyclonal Antibody (Product # PA5-82474) shows low expression as expected.
            View Product

            ATP1B1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            ATP1B1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            ATP1B1 Antibody
            ATP1B1 Antibody
            ATP1B1 Polyclonal Antibody

            Product Details

            PA5-82474

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            0.04-0.4 µg/mL
            -

            Immunohistochemistry (Paraffin) (IHC (P))

            1:200-1:500
            -
            Product Specifications

            Species Reactivity

            Human

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Recombinant protein corresponding to Human ATP1B1. Recombinant protein control fragment (Product #RP-90297).
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            0.1 mg/mL

            Purification

            Antigen affinity chromatography

            Storage buffer

            PBS, pH 7.2, with 40% glycerol

            Contains

            0.02% sodium azide

            Storage conditions

            Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_2789632

            Product Specific Information

            Immunogen sequence: SEFKPTYQDR VAPPGLTQIP QIQKTEISFR PNDPKSYEAY VLNIVRFLEK YKDSAQRDDM IFEDCGDVPS EPKERGDFNH ERGERKVCRF KLEWLGNCSG LNDETYGYKE GKPCIIIKLN RVLGFKPKPP KNESLETYPV MKYNPN

            Highest antigen sequence indentity to the following orthologs: Mouse - 93%, Rat - 93%.

            Target Information

            The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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            Bioinformatics

            Protein Aliases: adenosinetriphosphatase; ATPase, Na+/K+ transporting, beta 1 polypeptide; Beta 1-subunit of Na(+),K(+)-ATPase; MGC1798; Na+/K+ ATPase Beta; Na, K-ATPase beta-1 polypeptide; OTTHUMP00000032537; OTTHUMP00000032538; Sodium Potassium ATPase; sodium pump subunit beta-1; sodium-potassium ATPase subunit beta 1 (non-catalytic); sodium/potassium-dependent ATPase beta-1 subunit; Sodium/potassium-dependent ATPase subunit beta-1; sodium/potassium-transporting ATPase beta-1 chain; Sodium/potassium-transporting ATPase subunit beta-1

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            Gene Aliases: ATP1B; ATP1B1

            View more View less

            UniProt ID: (Human) P05026

            View more View less

            Entrez Gene ID: (Human) 481

            View more View less

            Function(s)

            ATPase activator activity sodium:potassium-exchanging ATPase activity protein binding ATP binding protein C-terminus binding drug binding ATPase activity MHC class II protein complex binding potassium ion binding sodium ion binding ATPase binding primary active transporter

            Process(es)

            response to hypoxia positive regulation of defense response to virus by host cellular calcium ion homeostasis cellular sodium ion homeostasis cell adhesion potassium ion import establishment or maintenance of transmembrane electrochemical gradient regulation of gene expression regulation of cardiac muscle contraction by calcium ion signaling cellular potassium ion homeostasis positive regulation of ATPase activity ion transmembrane transport sodium ion export from cell protein transport into plasma membrane raft ATP metabolic process protein stabilization leukocyte migration relaxation of cardiac muscle cardiac muscle contraction protein localization to plasma membrane membrane repolarization membrane repolarization during cardiac muscle cell action potential cell communication by electrical coupling involved in cardiac conduction ATP hydrolysis coupled transmembrane transport mitophagy in response to mitochondrial depolarization xenophagy positive regulation of potassium ion transmembrane transporter activity positive regulation of sodium ion export from cell positive regulation of calcium:sodium antiporter activity positive regulation of potassium ion import regulation of cardiac conduction potassium ion import across plasma membrane
            It has to be done as per old AB suggested Products section.
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