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Product Details
H00000534-M02
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2b, lambda
Class
Monoclonal
Type
Antibody
Clone
2E11
Immunogen
ATP6V1G2 (NP_569730, 41 a.a. approximately 118 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: QMEVEQYRRE REHEFQSKQQ AAMGSQGNLS AEVEQATRRQ VQGMQSSQQR NRERVLAQLL GMVCDVRPQV HPNYRISA
Target Information
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of three V1 domain G subunit proteins. This gene had previous gene symbols of ATP6G and ATP6G2. Alternatively spliced transcript variants encoding different isoforms have been described. Read-through transcription also exists between this gene and the downstream DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B (DDX39B) gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATPase, H+ transporting, lysosomal (vacuolar proton pump); ATPase, H+ transporting, lysosomal 13kD, V1 subunit G; ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2; ATPase, H+ transporting, V1 subunit G; H(+)-transporting two-sector ATPase, subunit G2; lysosomal 13kDa; V-ATPase 13 kDa subunit 2; V-ATPase subunit G 2; V-type proton ATPase subunit G 2; vacuolar ATP synthase subunit G 2; vacuolar ATPase NG38; vacuolar proton pump G subunit 2; Vacuolar proton pump subunit G 2
Gene Aliases: 1500002D01Rik; ATP6G; ATP6G2; ATP6V1G2; NG38; VAG2; VMA10
UniProt ID: (Human) O95670, (Mouse) Q9WTT4
Entrez Gene ID: (Human) 534, (Rat) 368044, (Mouse) 66237
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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