Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 1
Positive test controls include: HCT116.
Immunogen sequence: VTAARNFGYV FLSRTQDTVT IMELGEERVY QVLAIMDFNS TRKRMSVLVR KPEGAICLYT KGADTVIFER LHRRGAMEFA TEEALAAFAQ ETLRTLCLAY REVAEDIYED WQQRHQEASL LLQNRAQALQ QLLGATAIED RLQDGVPETI KCLKKSNIKI WVLTGDKQET AVNIGFACEL LSENMLILEE KEISRILETY WENSNNLLTR ESLSQVKLAL VINGDFLDKL LVSLRKEPRA LAQNVNMDEA WQELGQSRRD FLYARRLSLL CRRFGLPLAA PPAQDSRARR SSEVLQERAF V
P4-ATPase flippase which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. May be responsible for the maintenance of asymmetric distribution of phosphatidylserine (PS) in spermatozoa membranes. Involved in acrosome reactions and binding of spermatozoa to zona pellucida.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: aminophospholipid translocase ATP8B3; ATPase class I type 8B member 3; ATPase, aminophospholipid transporter, class I, type 8B, member 3; ATPase, class I, type 8B, member 3; Phospholipid-transporting ATPase IK; potential phospholipid-transporting ATPase IK; probable phospholipid-transporting ATPase IK
Gene Aliases: ATP1K; ATP8B3; ATPIK; FOS37502_2
UniProt ID: (Human) O60423
Entrez Gene ID: (Human) 148229
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