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Invitrogen
AZIN1 Polyclonal Antibody
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Application
FIGURE: 1 / 3
AZIN1 Antibody (PA5-97491) in IHC (P)
Immunohistochemical analysis of AZIN1 in paraffin embedded human adrenal gland tissue using a AZIN1 polyclonal antibody (Product # PA5-97491) at a dilution of 1:100.
Product Details
PA5-97491
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Antizyme inhibitor 1 protein (101-400AA)
Conjugate
Unconjugated
Form
Liquid
Concentration
2 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2812107
Target Information
Antizyme inhibitor (AZIN1) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding. Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Antizyme inhibitor 1; AZI; O OAZIN; ODC antizyme inhibitor; Ornithine decarboxylase antizyme inhibitor
Gene Aliases: 1700085L02Rik; AZI; AZIA1; AZIN1; OAZI; OAZIN; ODC1L
UniProt ID: (Human) O14977, (Mouse) O35484
Entrez Gene ID: (Human) 51582, (Mouse) 54375
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