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Histones are nuclear proteins that play an important role in maintaining the structure of the chromosome in eukaryotes. The nucleosome is made up of around 146bp of DNA, which enfolds around a histone octomer unit comprising of four major histones, H2A, H2B, H3 and H4. An important role of H2A is to ensure proper assembly or functioning of the centrometre. They also play an important role in gene regulation. The protein can be modified by acetylation and phosphorylation.
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Protein Aliases: H2A histone family, member C; H2A histone family, member P; H2A.1; H2A/d; H2ak; HIST1H2AJ; histone 1, H2ag; histone 1, H2ai; Histone H2A type 1; histone H2A/e; histone H2A/p; Histone H2A/ptl
Gene Aliases: H2A.1b; H2A/c; H2A/p; H2AC11; H2AC13; H2AC15; H2AC16; H2AC17; H2AFC; H2AFD; H2AFI; H2AFN; H2AFP; H2AG; HIST1H2AG; HIST1H2AI; HIST1H2AK; HIST1H2AL; HIST1H2AM; pH2A/f
UniProt ID: (Human) P0C0S8
Entrez Gene ID: (Human) 8969, (Human) 8329
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