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Acinus Antibody (720313) in WB
Western blot analysis was performed on Nuclear extracts (30 µg lysate) of K-562 (Lane 1), Raji (Lane 2), HeLa (Lane 3), Jurkat (Lane 4), HEL 92.1.7 (Lane 5), Hep G2 (Lane 6) and HL-60 (Lane 7). The blots were probed with Anti-ACINUS Rabbit Polyclonal Antibody (Product # 720313, 1-2 µg/mL) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal Secondary Antibody, HRP conjugate (Product # A27036, 0.4 µg/mL, 1:2500 dilution). Two isoforms of 220 kDa (ACINUS L) and 84 kDa (ACINUS S) corresponding to ACINUS was o... View More
产品信息
720313
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptides corresponding to human ACINUS [1) aa1085-aa1099 2) aa1323-aa1341]
偶联物
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2665122
产品详细信息
This antibody is predicted to react with Monkey, Bovine, Sheep
靶标信息
ACINUS (apoptotic chromatin condensation inducer in the nucleus) is an induced of chromatin condensation. ACINUS is cleaved by caspase-3 and an additional unknown protease generating a small active peptide, p17, which causes chromatin condensation in vitro when it is added to purified nuclei. ACINUS also induces apoptotic chromatin condensation in cells. ACINUS is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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