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Immunogen sequence: FAHLSHGDSP VSTSTPLPEK TLASFSTQWS LDRSRTPRGL DDELDTGDAK FFQVIEQLNS QKQWKQSKDF NPLTLYFREK EMEKEYRLSA IP
Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 88%.
This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: A cyclase IV; Adenylate cyclase type 4; Adenylate cyclase type IV; Adenylyl cyclase 4; ATP pyrophosphate-lyase 4; KIAA4004
Gene Aliases: AC4; ADCY4
UniProt ID: (Human) Q8NFM4
Entrez Gene ID: (Human) 196883
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