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Adenylate Cyclase 4 Antibody (PA5-75425) in WB
Western blot analysis of Adenylate Cyclase 4 in Lane 1: HCT116 whole cell lysate (20 µg), Lane 2: A549 whole cell lysate (40 µg), Lane 3: U-87MG whole cell lysate (40 µg), Lane 4: C6 whole cell lysate (40 µg), Lane 5: CT26 whole cell lysate (40 µg). Samples were incubated with Adenylate Cyclase 4 polyclonal antibody (Product # PA5-75425) at a dilution of 1:500.
Product Details
PA5-75425
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids 190-240 of Human Adenylate Cyclase 4.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2719153
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A cyclase IV; Adenylate cyclase type 4; Adenylate cyclase type IV; Adenylyl cyclase 4; ATP pyrophosphate-lyase 4; KIAA4004
Gene Aliases: AC4; ADCY4; mKIAA4004
UniProt ID: (Human) Q8NFM4, (Mouse) Q91WF3
Entrez Gene ID: (Human) 196883, (Rat) 54223, (Mouse) 104110
renal water homeostasis
cAMP biosynthetic process
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
cAMP-mediated signaling
activation of protein kinase A activity
cellular response to glucagon stimulus
intracellular signal transduction
cyclic nucleotide biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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