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Product Details
PA5-101284
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human ADCY5(Accession O95622), corresponding to amino acid residues Q867-S917.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2850723
Product Specific Information
Antibody detects endogenous levels of total ADCY5/6.
Target Information
Adenylate cyclase 5/6 encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A cyclase V; A cyclase VI; AC5; AC6; ACVI; adcy5; Adenylate cyclase type 5; Adenylate cyclase type 6; Adenylate cyclase type V; Adenylate cyclase type VI; Adenylyl cyclase 5; Adenylyl cyclase 6; adenylyl cyclase type V; ATP pyrophosphate-lyase 5; ATP pyrophosphate-lyase 6; Ca(2+)-inhibitable adenylyl cyclase
Gene Aliases: AC5; AC6; ACVI; ADCY5; ADCY6; ADCYB; AW121902; FDFM; KIAA0422; LCCS8; mKIAA0422
UniProt ID: (Human) O95622, (Human) O43306, (Rat) Q04400, (Mouse) P84309, (Rat) Q03343
Entrez Gene ID: (Human) 111, (Human) 112, (Rat) 64532, (Mouse) 224129, (Rat) 25289, (Mouse) 11512
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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