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Immunogen sequence: ECSSWYYYVT MPMPASTFTI AVGCWTEMKM ETWSSNDLAT ERPFSPSEAN FRHVGVCSHM EYPCRFQNAS ATTQEIIPHR VFAPVCLTGA CQETLLRLIP PCLSAAHSVL GAHPFSRLDV LIVPANFPSL GMA
Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 74%.
Aminopeptidases catalyze the hydrolysis of amino acid residues from the N-terminus of peptide or protein substrates. Able to cleave angiotensin III to generate angiotensin IV, a bioactive peptide of the renin-angiotensin pathway. Not able to cleave angiotensin I and angiotensin II. May play a role in the proteolytic processing of bioactive peptides in tissues such as testis and heart.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Aminopeptidase O; AP-O; AP-OFLJ55832; FLJ14675; FLJ40923
Gene Aliases: AOPEP; AP-O; APO; C90RF3; C9orf3; ONPEP
UniProt ID: (Human) Q8N6M6
Entrez Gene ID: (Human) 84909
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