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Application
FIGURE: 1 / 3
Angiopoietin 1 Antibody (PA5-46968) in IHC (P)
Immunohistochemical analysis of Angiopoietin 1 in immersion fixed paraffin-embedded sections of human prostate array. Samples were incubated in Angiopoietin 1 polyclonal antibody (Product # PA5-46968) using a dilution of 5 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown) and counterstained with hematoxylin (blue). Lower panel shows a lack of labeling... View More
Product Details
PA5-46968
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant human Angiopoietin-1 Ser20-Phe498
Conjugate
Unconjugated
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2607762
Product Specific Information
In direct ELISAs, less than 2% cross-reactivity with recombinant human (rh) Angiopoietin-2, rhAngiopoietin-4, and rhAngiopoietin-like Factor/CDT6 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ANG-1; Angiopoietin-1
Gene Aliases: 1110046O21Rik; AGP1; AGPT; Ang-1; ANG1; ANGPT1; KIAA0003
UniProt ID: (Human) Q15389, (Mouse) O08538
Entrez Gene ID: (Human) 284, (Mouse) 11600
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