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Alomone Labs, LTD
Anoctamin-5 Polyclonal Antibody
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Product Details
ACL-015-200UL
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)TKMEIPRTHQEYE, corresponding to amino acid residues 532-544 of mouse ANO5, 2ndintracellular loop
Conjugate
Unconjugated
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
Ano5 does not exhibit calcium-activated chloride channel (CaCC) activity. The Ano5 gene encodes a member of the anoctamin family of transmembrane proteins. The Ano5 protein is likely a calcium activated chloride channel. Mutations in the Ano5 gene have been associated with gnathodiaphyseal dysplasia. Alternatively spliced transcript variants have been described for Ano5. Diseases associated with ANO5 include Gnathodiaphyseal Dysplasia and Miyoshi Muscular Dystrophy 3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: anoctamin 5; Anoctamin-5; Gnathodiaphyseal dysplasia 1 protein homolog; integral membrane protein GDD1; Transmembrane protein 16E
Gene Aliases: 9330162L24; Ano5; Gdd1; RGD1564265; Tmem16e
UniProt ID: (Mouse) Q75UR0
Entrez Gene ID: (Mouse) 233246, (Rat) 308637
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