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产品信息
16414-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Antithrombin III Fusion Protein Ag9565 (1-259 aa encoded by BC022309)
偶联物
Unconjugated
形式
Liquid
浓度
0.17 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MYSNVIGTV TSGKRKVYLL SLLLIGFWDC VTCHGSPVDI CTAKPRDIPM NPMCIYRSPE KKATEDEGSE QKIPEATNRR VWELSKANSR FATTFYQHLA DSKNDNDNIF LSPLSISTAF AMTKLGACND TLQQLMEVFK FDTISEKTSD QIHFFFAKLN CRLYRKANKS SKLVSANRLF GDKSLTFNDL YVSDAFHKAF LEVNEEGSEA AASTAVVIAG RSLNPNRVTF KANRPFLVFI REVPLNTIIF MGRVANPCVK (1-259 aa encoded by BC022309)
靶标信息
The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Antithrombin; Antithrombin 3; Antithrombin-III; ATIII; MGC22579; serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1; Serpin C1; serpin peptidase inhibitor clade C member 1; serpin peptidase inhibitor, clade C (antithrombin), member 1
基因别名: AT3; AT3D; ATIII; PRO0309; SERPINC1; THPH7
UniProt ID: (Human) P01008
Entrez Gene ID: (Human) 462
