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Proteintech
Antithrombin III Monoclonal Antibody (2B2E5)
Product Details
66052-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Not Applicable
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2B2E5
Immunogen
Antithrombin III Fusion Protein Ag9880 (1-259 aa encoded by BC022309)
Conjugate
Form
Liquid
Concentration
0.62 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MYSNVIGTV TSGKRKVYLL SLLLIGFWDC VTCHGSPVDI CTAKPRDIPM NPMCIYRSPE KKATEDEGSE QKIPEATNRR VWELSKANSR FATTFYQHLA DSKNDNDNIF LSPLSISTAF AMTKLGACND TLQQLMEVFK FDTISEKTSD QIHFFFAKLN CRLYRKANKS SKLVSANRLF GDKSLTFNDL YVSDAFHKAF LEVNEEGSEA AASTAVVIAG RSLNPNRVTF KANRPFLVFI REVPLNTIIF MGRVANPCVK (1-259 aa encoded by BC022309)
Target Information
The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: anti-thrombin 3; antithrombin; Antithrombin 3; antithrombin III; Antithrombin-III; ATIII; MGC22579; serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1; serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1; Serpin C1; serpin peptidase inhibitor clade C member 1; serpin peptidase inhibitor, clade C (antithrombin), member 1; serpin peptidase inhibitor, clade C, member 1
Gene Aliases: AI114908; At-3; AT3; AT3D; ATIII; PRO0309; SERPINC1; THPH7
UniProt ID: (Human) P01008, (Mouse) P32261
Entrez Gene ID: (Human) 462, (Mouse) 11905, (Rat) 304917
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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