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Invitrogen
B7-H6 Polyclonal Antibody
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Application
FIGURE: 1 / 1
B7-H6 Antibody (PA5-49085) in WB
Western blot analysis of B7-H6 in various lysates. Samples were incubated with B7-H6 polyclonal antibody (Product # PA5-49085) using a dilution of 1:2,000 followed by Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at a dilution of 1:10,000. Lysates/proteins: 20 µg per lane. Lane 1: 293T/17 whole cell lysate; Lane 2: Daudi whole cell lysate; Lane 3: Hela whole cell lysate; Lane 4: K562 whole cell lysate. Predicted band size: 51 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
Product Details
PA5-49085
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 389-415 amino acids from the C-terminal region of human B7H6.
Conjugate
Unconjugated
Form
Liquid
Concentration
2 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2634541
Target Information
B7-H6 (NCR3LG1) is a transmembrane endogenous ligand expressed on the surfaces of tumor cells. B7-H6 binds with NKp30 present on NK cells. Binding of B7-H6 to NKp30 causes the ligation of NKp30 subsequently inducing NK cell activation and target cell cytolysis. B7-H6 is not constitutively expressed on normal tissue. Whether it can be expressed endogenously under certain conditions is under investigation. B7-H6 has been detected on circulating pro-inflammatory CD14(+)CD16(+) monocytes in some patients with sepsis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: B7 homolog 6; B7-H6; DKFZp686I21167; Natural cytotoxicity triggering receptor 3 ligand 1; putative Ig-like domain-containing protein DKFZp686O24166/DKFZp686I21167
Gene Aliases: B7-H6; B7H6; DKFZp686O24166; NCR3LG1
UniProt ID: (Human) Q68D85
Entrez Gene ID: (Human) 374383
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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