Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Immunogen sequence: KTLELRVAYL DPLELSEGKV LSLPLNSSAV VNCSVHGLPT PALRWTKDST PLGDGPMLSL SSITFDSNGT YVCEASLPTV PVLSRTQNFT LLVQGSPELK TAEIEPKADG SWREGDEVTL ICSARGHPDP KLSWSQLGGS PAEPIPGRQG WVSSSLTLKV TSALSRDGIS CEASNPHGNK RHVFHFGTVS PQTSQA; Positive Samples: U251, HepG2; Cellular Location: Membrane, Single-pass type I membrane protein
Lutheran blood group glycoprotein is a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five, N-terminus, extracellular immunoglobulin domains, a single transmembrane domain, and a short, C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Two transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: antigen identified by monoclonal antibody F8; Auberger B antigen; B-CAM cell surface glycoprotein; B-cell adhesion molecule; Basal cell adhesion molecule; basal cell adhesion molecule (Lu and Au blood groups); basal cell adhesion molecule Lutheran blood group; CD239; F8/G253 antigen; glycoprotein 95kDa; Lutheran antigen; Lutheran blood group; Lutheran blood group glycoprotein; Lutheran blood group variant LUGA
Gene Aliases: AU; BCAM; CD239; LU; MSK19
UniProt ID: (Human) P50895
Entrez Gene ID: (Human) 4059
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