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Invitrogen

BDKRB2 Recombinant Rabbit Monoclonal Antibody (JU39-04)

View all (20) BDKRB2 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (2)

Application

FIGURE: 1 / 2

BDKRB2 Antibody (MA5-34627) in WB

Western blot analysis of BDKRB2 in MCF-7 cell lysate. Samples were incubated with BDKRB2 monoclonal antibody (Product # MA5-34627), at a dilution of 1:500.

BDKRB2 Antibody in Flow Cytometry (Flow)

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Product Details

MA5-34627

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

Flow Cytometry (Flow)

1:50-1:100

Immunoprecipitation (IP)

1:10-1:50

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

JU39-04

Immunogen

Recombinant protein within Human BDKRB2 aa 262-391

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

TBS, pH 7.4, with 40% glycerol, 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles, store in dark

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2848535

Product Specific Information

Positive Control: MCF-7, SH-SY5Y.

Target Information

Bradykinin B2 receptor (BDKRB2) expression has been reported in blood, brain, eye, kidney, liver, lung, prostate, skin, small intestine, synovium, uterus, and vessel. ESTs have been isolated from colon, connective tissue, heart, heart/melanocyte/uterus, and kidney libraries. It is associated with G-proteins that activate a phosphatidylinositol-calcium second messenger system.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: B2 bradykinin receptor; B2R; BK-2 receptor; BK-2R; BK-2Rs; DKFZp686O088

Gene Aliases: B2R; BDKRB2; BK-2; BK2; BKR2; BRB2

UniProt ID: (Human) P30411

Entrez Gene ID: (Human) 624

Function(s)

protease binding phosphatidylinositol phospholipase C activity bradykinin receptor activity protein binding beta-2 adrenergic receptor binding type 1 angiotensin receptor binding protein heterodimerization activity G-protein coupled receptor

Process(es)

acute inflammatory response to antigenic stimulus smooth muscle contraction inflammatory response cell surface receptor signaling pathway transmembrane receptor protein tyrosine kinase signaling pathway G-protein coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration blood circulation negative regulation of cell proliferation response to salt stress regulation of vasoconstriction negative regulation of peptidyl-serine phosphorylation maintenance of blood-brain barrier vasoconstriction vasodilation response to drug regulation of vascular permeability negative regulation of blood pressure arachidonic acid secretion cellular response to hypoxia negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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