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This target displays homology in the following species: Mouse: 100%; Rat: 93%
This gene encodes a member of the basic helix-loop-helix transcription factor family. Members of this family contain two highly conserved and functionally distinct domains: the basic domain targets sequence-specific DNA binding, while the helix-loop-helix domain facilitates protein interaction. Studies of a related gene in mouse suggest that the encoded protein may function as a transcriptional repressor in the pancreas and brain, and that it is required for normal retinal function.
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Protein Aliases: basic helix-loop-helix domain containing, class B4; beta-cell E-box transactivating factor 4; bHLHb4; bHLHe23; Class B basic helix-loop-helix protein 4; Class E basic helix-loop-helix protein 23
Gene Aliases: A930001L02Rik; BETA4; Bhlhb4; Bhlhe23; H20
UniProt ID: (Mouse) Q8BGW3
Entrez Gene ID: (Mouse) 140489
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