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Invitrogen

BNP Polyclonal Antibody

Name: BNP Polyclonal Antibody
Brand: Invitrogen
SKU: PA596084
Price: 518.0 EUR

8 Published Figures

5 References

View all (50) BNP antibodies

Datasheet

Protocols

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Catalog # PA5-96084

Price (EUR)

518,00

100 µL

Estimated availability date: 01-Jul-2025

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Datasheet

Protocols

Questions & Answers

Tech Support

Antibody Testing Data (5)
Published Figures (8)

Application

BNP Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 13

BNP Antibody (PA5-96084) in ICC/IF

Immunofluorescence analysis of BNP in rat heart cells. Samples were incubated with BNP Polyclonal antibody (Product # PA5-96084) using a dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining.

BNP Antibody in Immunohistochemistry (Paraffin) (IHC (P))

BNP Antibody in Western Blot, Immunohistochemistry (WB, IHC)

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Product Details

PA5-96084

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:5,000

View 3 publications 3 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

Immunocytochemistry (ICC/IF)

1:50-1:200

ELISA (ELISA)

1 µg/mL

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 35-134 of human BNP (NP_0025121)

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

1.56 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.09% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2807886

Product Specific Information

Positive Samples: Rat heart

Immunogen sequence: SPKMVQGSGC FGRKMDR

Target Information

This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Dronedarone Attenuates Ang II-Induced Myocardial Hypertrophy Through Regulating SIRT1/FOXO3/PKIA Axis.

Korean circulation journal

Chen C,Hu S,Hu HJ,Liu ZX,Wu XT,Zou T,Su H

Published figure using BNP polyclonal antibody (Product # PA5-96084) in Western Blot

Mon Apr 01 00:00:00 UTC 2024

VDR Regulates BNP Promoting Neurite Growth and Survival of Cochlear Spiral Ganglion Neurons through cGMP-PKG Signaling Pathway.

Cells

Zhang X,Zhou K,Tian K,Zhu Q,Liu W,Liu Z,An X,Tian C,Li Y,Lu F,Sun F,Zha D

Published figure using BNP polyclonal antibody (Product # PA5-96084) in Immunohistochemistry

Wed Nov 23 00:00:00 UTC 2022

VDR Regulates BNP Promoting Neurite Growth and Survival of Cochlear Spiral Ganglion Neurons through cGMP-PKG Signaling Pathway.

Cells

Zhang X,Zhou K,Tian K,Zhu Q,Liu W,Liu Z,An X,Tian C,Li Y,Lu F,Sun F,Zha D

Published figure using BNP polyclonal antibody (Product # PA5-96084) in Immunohistochemistry

Wed Nov 23 00:00:00 UTC 2022

A remarkable adaptive paradigm of heart performance and protection emerges in response to marked cardiac-specific overexpression of ADCY8.

eLife

Tarasov KV,Chakir K,Riordon DR,Lyashkov AE,Ahmet I,Perino MG,Silvester AJ,Zhang J,Wang M,Lukyanenko YO,Qu JH,Barrera MC,Juhaszova M,Tarasova YS,Ziman B,Telljohann R,Kumar V,Ranek M,Lammons J,Bychkov R,de Cabo R,Jun S,Keceli G,Gupta A,Yang D,Aon MA,Adamo L,Morrell CH,Otu W,Carroll C,Chambers S,Paolocci N,Huynh T,Pacak K,Weiss R,Field L,Sollott SJ,Lakatta EG

PA5-96084 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to show that TGAC8 mice show classical cardiac hypertrophy markers were absent in TGAC8, and that total left ventricular mass was not increased: a reduced LV cavity volume in TGAC8 was encased by thicker LV walls harboring an increased number of small cardiac myocytes, and a network of small interstitial proliferative non-cardiac myocytes compared to wild type littermates compared to wild type littermates.

Wed Dec 14 00:00:00 UTC 2022

Nuclear-mitochondrial communication involving miR-181c plays an important role in cardiac dysfunction during obesity.

Journal of molecular and cellular cardiology

Roman B,Kaur P,Ashok D,Kohr M,Biswas R,O'Rourke B,Steenbergen C,Das S

PA5-96084 was used in Western Blot to study the effects of variable levels of miR-181c on obesity-induced cardiac dysfunction.

Wed Jul 01 00:00:00 UTC 2020

Bioinformatics

Protein Aliases: BNP-32; Brain natriuretic factor; Brain natriuretic factor prohormone; brain natriuretic peptide; brain type natriuretic peptide; Gamma-brain natriuretic peptide; Iso-ANP; natriuretic peptide precursor B; natriuretic peptide precursor type B; Natriuretic peptides B; natriuretic protein; preproBNP; type-B natriuretic factor

Gene Aliases: AA408272; BNF; BNP; NPPB

UniProt ID: (Human) P16860, (Rat) P13205, (Mouse) P40753

Entrez Gene ID: (Human) 4879, (Rat) 25105, (Mouse) 18158

Function(s)

receptor binding hormone activity protein binding diuretic hormone activity peptide hormone receptor binding

Process(es)

response to hypoxia negative regulation of systemic arterial blood pressure cGMP biosynthetic process inflammatory response receptor guanylyl cyclase signaling pathway heart development regulation of blood pressure response to organic cyclic compound negative regulation of cell growth response to lipopolysaccharide positive regulation of urine volume positive regulation of renal sodium excretion response to drug response to peptide hormone negative regulation of smooth muscle cell proliferation regulation of blood vessel size response to calcium ion cellular response to mechanical stimulus positive regulation of collecting lymphatic vessel constriction cell surface receptor signaling pathway body fluid secretion negative regulation of angiogenesis regulation of vasodilation regulation of vascular permeability

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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