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Recommended positive controls: U87-MG.
Predicted reactivity: Mouse (94%), Rat (94%), Bovine (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Scaffold subunit of various histone acetyltransferase (HAT) complexes, such as the MOZ/MORF and HBO1 complexes, which have a histone H3 acetyltransferase activity (PubMed:16387653, PubMed:26620551, PubMed:26677226). Plays a role in DNA replication initiation by directing KAT7/HBO1 specificity towards histone H3 'Lys-14' acetylation (H3K14ac), thereby facilitating the activation of replication origins (PubMed:26620551). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity (PubMed:16387653). [UniProt]
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: bromodomain and PHD finger containing, 3; Bromodomain and PHD finger-containing protein 3
基因别名: BRPF3; KIAA1286
UniProt ID: (Human) Q9ULD4
Entrez Gene ID: (Human) 27154