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Antibody detects endogenous levels of total BRWD3.
The protein encoded by this gene contains a bromodomain and several WD repeats. It is thought to have a chromatin-modifying function, and may thus play a role in transcription. Mutations in this gene cause mental retardation X-linked type 93, which is also referred to as mental retardation X-linked with macrocephaly. This gene is also associated with translocations in patients with B-cell chronic lymphocytic leukemia. [provided by RefSeq, May 2010].
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Protein Aliases: bromo domain-containing protein disrupted in leukemia; bromodomain and WD repeat domain containing 3; Bromodomain and WD repeat-containing protein 3; BRWD3-H; BRWD3-I; BRWD3-K; BRWD3-P; novel WD repeat domain protein
Gene Aliases: BRODL; BRWD3; D030064D06Rik; Gm596; MRX93; RGD1559445
UniProt ID: (Human) Q6RI45, (Mouse) A2AHJ4
Entrez Gene ID: (Human) 254065, (Rat) 317213, (Mouse) 382236
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