Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Immunogen sequence: YCQENPSAFS SFDFSYSGAE RIQSVNHIEG LTKPGEENLF KLVTDKKIKQ PNGFCDNYSA QKYGIIENVN KHNFQAKPQS GHYDPEEGPK HLDGLSQNTY QDLLESQGHS NSHRTRGGDN SRVNRTQVSC FSNN
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 82%.
Is required for meiosis completion in both male and female germ cells. Confers stability to numerous meiotic mRNAs in gonads allowing proper initiation and progression into meiosis prophase I. The function may involve YTHDC2 and is independent of induction by retinoic acid (RA). Maintains an extended meiotic prophase I by properly promoting the transition from a mitotic to a meiotic cell cycle program by binding transcripts through its interaction with YTHDC2 that regulate the mitotic cell cycle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Meiosis-specific coiled-coil domain-containing protein MEIOC; Meiosis-specific with coiled-coil domain protein; uncharacterized protein C17orf104
Gene Aliases: C17orf104; MEIOC
UniProt ID: (Human) A2RUB1
Entrez Gene ID: (Human) 284071
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