Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This antibody is raised against C1qB which is the B-chain polypeptide of human complement subcomponent C1q.
Immunogen sequence: LIDISQAQL SCTGPPAIPG IPGIPGTPGP DGQPGTPGIK GEKGLPGLAG DHGEFGEKGD PGIPGNPGKV GPKGPMGPKG GPGAPGAPGP KGESGDYKAT QKIAFSATRT INVPLRRDQT IRFDHVITNM NNNYEPRSGK FTCKVPGLYY FTYHASSRGN LCVNLMRGRE RAQKVVTFCD YAYNTFQVTT GGMVLKLEQG ENVFLQATDK NSLLGMEGAN SIFSGFLLFP DMEA (21-253 aa encoded by BC008983)
C1QB is a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C1QTNF5; complement C1q chain B; Complement C1q subcomponent subunit B; complement component 1, q subcomponent, B chain; complement component 1, q subcomponent, beta polypeptide; complement component C1q, B chain; complement subcomponent C1q chain B; CTRP5; DKFZP586B0621; LORD
Gene Aliases: C1QB
UniProt ID: (Human) P02746
Entrez Gene ID: (Human) 713
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