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Alomone Labs, LTD
CACNA2D3 (CaV alpha 2 delta 3) (extracellular) Polyclonal Antibody
Application
FIGURE: 1 / 3
CACNA2D3 (CaV alpha 2 delta 3) (extracellular) Antibody (ACC-103-200UL) in ICC/IF
Expression of CaV alpha 2 delta 3 in rat PC12 cells - Cell surface detection of CaV alpha 2 delta 3 in intact living PC12 cells. Extracellular staining of cells using Anti-CACNA2D3 (CaV alpha 2 delta 3) (extracellular) Antibody (#ACC-103), (1:25) followed by goat Anti-rabbit-AlexaFluor-594 secondary Antibody .
Product Details
ACC-103-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CSWWHSDMTAKAQK, corresponding to amino acid residues 942-955 of rat CaV alpha 2 delta 3, Extracellular
Conjugate
Unconjugated
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
CACNA2D3 is a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha 2 delta-3; alpha2delta3; calcium channel alpha2-delta3 subunit; calcium channel, voltage dependent, alpha2/delta subunit 3; calcium channel, voltage-dependent, alpha 2/delta 3 subunit; calcium channel, voltage-dependent, alpha 2/delta subunit 3; CaV alpha2delta3; Voltage-dependent calcium channel subunit alpha-2/delta-3; Voltage-gated calcium channel subunit alpha-2/delta-3
Gene Aliases: CACNA2D3; Cacnad3; HSA272268
UniProt ID: (Human) Q8IZS8, (Rat) Q8CFG5, (Mouse) Q9Z1L5
Entrez Gene ID: (Human) 55799, (Rat) 306243, (Mouse) 12294
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