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Sequence of this protein is as follows: MASEELQKDL EEVKVLLEKA TRKRVRDALT AEKSKIETEI KNKMQQKSQK KAELLDNEKP AAVVAPITTG YTVKISNYGW DQSDKFVKIY ITLTGVHQVP TENVQVHFTE RSFDLLVKNL NGKSYSMIVN NLLKPISVEG SSKKVKTDTV LILCRKKVEN TRWDYLTQVE KECKEKEKPS YDTETDPSEG LMNVLKKIYE DGDDDMKRTI NKAWVESREK QAKGDTEF
Calcyclin is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2A9; 5B10; CABP; CACY; CacyBP; Calcyclin; Calcyclin-binding protein; growth-inhibiting gene 5 protein; hCacyBP; PRA; RP1-102G20.6; S100A6; S100A6-binding protein; Siah-interacting protein; Siah-interacting protein (SIP)
Gene Aliases: CACYBP; GIG5; PNAS-107; S100A6BP; SIP
UniProt ID: (Human) Q9HB71
Entrez Gene ID: (Human) 27101
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