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Application
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CARP Antibody (PA5-98410) in IHC (P)
Immunohistochemical analysis of CARP in paraffin embedded human skeletal muscle tissue using a CARP polyclonal antibody (Product # PA5-98410) at a dilution of 1:100.
Product Details
PA5-98410
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Ankyrin repeat domain-containing protein 1 protein (1-130AA)
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2813023
Target Information
The protein encoded by this gene is localized to the nucleus of endothelial cells and is induced by IL-1 and TNF-alpha stimulation. Studies in rat cardiomyocytes suggest that this gene functions as a transcription factor. Interactions between this protein and the sarcomeric proteins myopalladin and titin suggest that it may also be involved in the myofibrillar stretch-sensor system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ankyrin repeat domain 1 (cardiac muscle); Ankyrin repeat domain-containing protein 1; Cardiac ankyrin repeat protein; Cytokine-inducible gene C-193 protein; Cytokine-inducible nuclear protein; liver ankyrin repeat domain 1
Gene Aliases: ALRP; ANKRD1; bA320F15.2; C-193; C193; CARP; CVARP; HA1A2; MCARP
UniProt ID: (Human) Q15327
Entrez Gene ID: (Human) 27063
negative regulation of transcription from RNA polymerase II promoter
positive regulation of neuron projection development
cellular response to drug
skeletal muscle cell differentiation
response to muscle stretch
muscle cell differentiation
positive regulation of apoptotic process
positive regulation of DNA damage response, signal transduction by p53 class mediator
sarcomere organization
positive regulation of transcription from RNA polymerase II promoter
positive regulation of protein secretion
cardiac muscle tissue morphogenesis
cellular response to lipopolysaccharide
cellular response to mechanical stimulus
cellular response to interleukin-1
cellular response to tumor necrosis factor
cellular response to organic cyclic compound
cellular response to hypoxia
cellular response to transforming growth factor beta stimulus
negative regulation of DNA biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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