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The protein encoded by this gene is localized to the nucleus of endothelial cells and is induced by IL-1 and TNF-alpha stimulation. Studies in rat cardiomyocytes suggest that this gene functions as a transcription factor. Interactions between this protein and the sarcomeric proteins myopalladin and titin suggest that it may also be involved in the myofibrillar stretch-sensor system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ankyrin repeat domain 1 (cardiac muscle); Ankyrin repeat domain-containing protein 1; Cardiac ankyrin repeat protein; Cytokine-inducible gene C-193 protein; Cytokine-inducible nuclear protein; liver ankyrin repeat domain 1
Gene Aliases: ALRP; ANKRD1; bA320F15.2; C-193; C193; CARP; CVARP; HA1A2; MCARP
UniProt ID: (Human) Q15327
Entrez Gene ID: (Human) 27063
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