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Product Details
13725-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CBR4 Fusion Protein Ag4678 (1-211 aa encoded by BC033650)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.21 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MDKVCAVFG GSRGIGRAVA QLMARKGYRL AVIARNLEGA KAAAGDLGGD HLAFSCDVAK EHDVQNTFEE LEKHLGRVNF LVNAAGINRD GLLVRTKTED MVSQLHTNLL GSMLTCKAAM RTMIQQQGGS IVNVGSIVGL KGNSGQSVYS ASKGGLVGFS RALAKEVARK KIRVNVVAPG FVHTDMTKDL KEEHLKKNIP LGRFGETIEV AH (1-211 aa encoded by BC033650)
Target Information
The heterotetramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis. Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD. The homotetramer has NADPH-dependent quinone reductase activity. Both homotetramer and the heterotetramer have broad substrate specificity and can reduce 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3-ketoacyl-[acyl-carrier-protein] reductase beta subunit; 3-oxoacyl-[acyl-carrier-protein] reductase; carbonic reductase 4; Carbonyl reductase family member 4; CBR4; KAR beta subunit; Quinone reductase CBR4; Short chain dehydrogenase/reductase family 45C member 1; short chain dehydrogenase/reductase family 45C, member 1
Gene Aliases: A730083J17Rik; BC009118; CBR4; SDR45C1
UniProt ID: (Human) Q8N4T8, (Rat) Q7TS56, (Mouse) Q91VT4
Entrez Gene ID: (Human) 84869, (Rat) 359725, (Mouse) 234309
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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