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Proteintech

CBY1 Polyclonal Antibody

3 References

View all (9) CBY1 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (9)

Application

CBY1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 9

CBY1 Antibody (12239-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human kidney using 12239-1-AP (CBY1 antibody) at dilution of 1:50 (under 40x lens).

CBY1 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

12239-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CBY1 Fusion Protein Ag2882 (41-126 aa encoded by BC016139)

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: GSPTMNLAG QSLKFENGQW IAETGVSGGV DRREVQRLRR RNQQLEEENN LLRLKVDILL DMLSESTAES HLMEKELDEL RISRKRK (41-126 aa encoded by BC016139)

Target Information

Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

DZIP1 regulates mammalian cardiac valve development through a Cby1-β-catenin mechanism.

Developmental dynamics : an official publication of the American Association of Anatomists

Guo L,Beck T,Fulmer D,Ramos-Ortiz S,Glover J,Wang C,Moore K,Gensemer C,Morningstar J,Moore R,Schott JJ,Le Tourneau T,Koren N,Norris RA

Fri Oct 01 00:00:00 UTC 2021

DZIP1 regulates mammalian cardiac valve development through a Cby1-β-catenin mechanism.

Developmental dynamics : an official publication of the American Association of Anatomists

Guo L,Beck T,Fulmer D,Ramos-Ortiz S,Glover J,Wang C,Moore K,Gensemer C,Morningstar J,Moore R,Schott JJ,Le Tourneau T,Koren N,Norris RA

Fri Oct 01 00:00:00 UTC 2021

DZIP1 regulates mammalian cardiac valve development through a Cby1-β-catenin mechanism.

Developmental dynamics : an official publication of the American Association of Anatomists

Guo L,Beck T,Fulmer D,Ramos-Ortiz S,Glover J,Wang C,Moore K,Gensemer C,Morningstar J,Moore R,Schott JJ,Le Tourneau T,Koren N,Norris RA

Fri Oct 01 00:00:00 UTC 2021

DZIP1 regulates mammalian cardiac valve development through a Cby1-β-catenin mechanism.

Developmental dynamics : an official publication of the American Association of Anatomists

Guo L,Beck T,Fulmer D,Ramos-Ortiz S,Glover J,Wang C,Moore K,Gensemer C,Morningstar J,Moore R,Schott JJ,Le Tourneau T,Koren N,Norris RA

Fri Oct 01 00:00:00 UTC 2021

Chibby promotes ciliary vesicle formation and basal body docking during airway cell differentiation.

The Journal of cell biology

Burke MC,Li FQ,Cyge B,Arashiro T,Brechbuhl HM,Chen X,Siller SS,Weiss MA,O'Connell CB,Love D,Westlake CJ,Reynolds SD,Kuriyama R,Takemaru K

Mon Oct 13 00:00:00 UTC 2014

Chibby promotes ciliary vesicle formation and basal body docking during airway cell differentiation.

The Journal of cell biology

Burke MC,Li FQ,Cyge B,Arashiro T,Brechbuhl HM,Chen X,Siller SS,Weiss MA,O'Connell CB,Love D,Westlake CJ,Reynolds SD,Kuriyama R,Takemaru K

Mon Oct 13 00:00:00 UTC 2014

Bioinformatics

Protein Aliases: ARPP-binding protein; chibby CTNNB1-mediated transcription inhibitor; chibby homolog 1; coiled-coil protein PIGEA-14; Cytosolic leucine-rich protein; PIGEA-14; PKD2 interactor, golgi and endoplasmic reticulum associated 1; PKD2 interactor, Golgi and endoplasmic reticulum-associated 1; polycystin-2 interactor, Golgi- and endoplasmic reticulum-associated protein, 14 kDa; Protein chibby homolog 1

Gene Aliases: 1110014P06Rik; ARB1; C22orf2; CBY; CBY1; HRIHFB2025; HS508I15A; PGEA1; PGEA14; PIGEA-14; PIGEA14

UniProt ID: (Human) Q9Y3M2, (Mouse) Q9D1C2, (Rat) Q8K4I6

Entrez Gene ID: (Human) 25776, (Mouse) 73739, (Rat) 246768

Function(s)

Process(es)

protein localization cell differentiation negative regulation of Wnt signaling pathway cilium assembly fat cell differentiation negative regulation of transcription, DNA-templated cardiac muscle cell differentiation negative regulation of canonical Wnt signaling pathway

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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CBY1 Polyclonal Antibody

CBY1 Antibody (12239-1-AP) in IHC (P)

Product Details

12239-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Function(s)

Process(es)

Performance Guarantee

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