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Immunogen sequence: QPLLKTPPAV LQPIAPQTTF GVQTQPQPQS LLQAQISAAS ITPLLQTQPQ PLLQQPQQKA GLLQPPVRIV SQPQPARRLD PPSRFSGRND RGDQVPNRKD DRSRERERER RRSRERSPQR KRSRERS
IFI-44 (interferon-induced protein 44), also known as p44 or MTAP44 (microtubule-associated protein 44), is a 444 amino acid protein that localizes to the cytoplasm and, upon induction by IFN-betas, aggregates to form microtubular structures. Human IFI-44 shares 97% sequence similarity with its chimp counterpart, suggesting a conserved role between species. The gene encoding IFI-44 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CARP-1; Cell cycle and apoptosis regulatory protein 1; Cell division cycle and apoptosis regulator protein 1; Death inducer with SAP domain; MGC44628; OTTHUMP00000019709; RP11-437A18.1
Gene Aliases: CARP1; CCAR1; DIS
UniProt ID: (Human) Q8IX12
Entrez Gene ID: (Human) 55749
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