Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
The antibody detects endogenous levels of total CCP3 / AGBL3 protein.
Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATP/GTP binding protein-like 3; ATP/GTP-binding protein-like 3; CBCP3; Cytosolic carboxypeptidase 3; Protein deglutamylase CCP3
Gene Aliases: 2900053G10Rik; 4930431N21Rik; 6530406M24Rik; AGBL3; CCP3
UniProt ID: (Human) Q8NEM8, (Mouse) Q8CDP0
Entrez Gene ID: (Human) 340351, (Mouse) 76223
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