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Invitrogen
CD162 Monoclonal Antibody (TC2), APC
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Product Details
MA1-10115
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
TC2
Immunogen
Human thymocytes
Conjugate
Excitation/Emission Max
651/660 nm
View spectra
Form
Liquid
Purification
Size-exclusion chromatography
Storage buffer
PBS, pH 7.4, with 0.2% BSA
Contains
15mM sodium azide
Storage conditions
4°C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11157431
Product Specific Information
This antibody reacts with an extracellular epitope of CD162, a 220 kDa type I integral membrane protein expressed as disulfide-linked homodimer (sialomucin family). CD162 is present on the most peripheral blood T lymphocytes, monocytes, granulocytes; it is also expressed on a subpopulation of B lymphocytes and CD34+ bone marrow cells.
Target Information
CD162 (PSGL-1) is a 120 kDa homodimer protein found on the surface of leukocytes and platelets. CD162 is known to bind CD62P (P-selectin), CD62L (L-selectin), and to a lower degree CD62E (E-selectin). These interactions play a critical role in leukocyte adhesion, rolling and extravasation. CD162 has been shown to be an important immune marker of T cell exhaustion in chronic viral infections and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD162; Cutaneous lymphocyte associated antigen; cutaneous lymphocyte-associated associated antigen; P-selectin glycoprotein ligand 1; PSGL-1; Selectin P ligand; SELPG
Gene Aliases: CD162; CLA; PSGL-1; PSGL1; SELPLG
UniProt ID: (Human) Q14242
Entrez Gene ID: (Human) 6404
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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