Product References
Cissus quadrangularis (Hadjod) Inhibits RANKL-Induced Osteoclastogenesis and Augments Bone Health in an Estrogen-Deficient Preclinical Model of Osteoporosis Via Modulating the Host Osteoimmune System.
Cells
Azam Z,Sapra L,Baghel K,Sinha N,Gupta RK,Soni V,Saini C,Mishra PK,Srivastava RK
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Wed Jan 04 00:00:00 EST 2023
Role of FGF10/FGFR2b Signaling in Homeostasis and Regeneration of Adult Lacrimal Gland and Corneal Epithelium Proliferation.
Investigative ophthalmology & visual science
Finburgh EN,Mauduit O,Noguchi T,Bu JJ,Abbas AA,Hakim DF,Bellusci S,Meech R,Makarenkova HP,Afshari NA
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Tue Jan 03 00:00:00 EST 2023
Single-cell transcriptomics reveals distinct cell response between acute and chronic pulmonary infection of Pseudomonas aeruginosa.
MedComm
Hu X,Wu M,Ma T,Zhang Y,Zou C,Wang R,Zhang Y,Ren Y,Li Q,Liu H,Li H,Wang T,Sun X,Yang Y,Tang M,Li X,Li J,Gao X,Li T,Zhou X
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Immunohistochemistry
Thu Dec 01 00:00:00 EST 2022
Valosin-containing protein (VCP/p97) inhibition reduces viral clearance and induces toxicity associated with muscular damage.
Cell death & disease
Del Rio Oliva M,Basler M
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2022
Withdrawn: Parecoxib inhibits inflammatory responses in a mouse model of sepsis.
FEBS open bio
No authors listed
16-0193 was used in Flow cytometry/Cell sorting to suggest that Parecoxib inhibits the inflammatory response and has protective effects against sepsis in mice, and may have potential as a novel therapeutic method for treating sepsis.
Sat Jan 01 00:00:00 EST 2022
High-yield enrichment of mouse small intestine intraepithelial lymphocytes by immunomagnetic depletion of EpCAM+ cells.
STAR protocols
Prakhar P,Gonzalez V,Park JH
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Fri Mar 18 00:00:00 EDT 2022
The ubiquitin ligase Peli1 inhibits ICOS and thereby Tfh-mediated immunity.
Cellular & molecular immunology
Huang X,Hao S,Liu J,Huang Y,Liu M,Xiao C,Wang Y,Pei S,Yu T,Xu J,Wang H,Dai D,Su X,Xiao Y
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Functional human IgA targets a conserved site on malaria sporozoites.
Science translational medicine
Tan J,Cho H,Pholcharee T,Pereira LS,Doumbo S,Doumtabe D,Flynn BJ,Schön A,Kanatani S,Aylor SO,Oyen D,Vistein R,Wang L,Dillon M,Skinner J,Peterson M,Li S,Idris AH,Molina-Cruz A,Zhao M,Olano LR,Lee PJ,Roth A,Sinnis P,Barillas-Mury C,Kayentao K,Ongoiba A,Francica JR,Traore B,Wilson IA,Seder RA,Crompton PD
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Wed Jun 23 00:00:00 EDT 2021
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions.
The Journal of experimental medicine
Ho TT,Dellorusso PV,Verovskaya EV,Bakker ST,Flach J,Smith LK,Ventura PB,Lansinger OM,Hérault A,Zhang SY,Kang YA,Mitchell CA,Villeda SA,Passegué E
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
The gammaherpesvirus 68 viral cyclin facilitates expression of LANA.
PLoS pathogens
Niemeyer BF,Sanford B,Gibson JE,Berger JN,Oko LM,Medina E,Clambey ET,van Dyk LF
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Mon Nov 01 00:00:00 EDT 2021
STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.
Cellular and molecular gastroenterology and hepatology
Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Mon Jan 24 00:00:00 EST 2022
Regulatory B Cells (Bregs) Inhibit Osteoclastogenesis and Play a Potential Role in Ameliorating Ovariectomy-Induced Bone Loss.
Frontiers in immunology
Sapra L,Bhardwaj A,Mishra PK,Garg B,Verma B,Mishra GC,Srivastava RK
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Thu Nov 04 00:00:00 EDT 2021
Comprehensive mutagenesis identifies the peptide repertoire of a p53 T-cell receptor mimic antibody that displays no toxicity in mice transgenic for human HLA-A*0201.
PloS one
Trenevska I,Anderson AP,Bentley C,Hassanali T,Wiblin S,Maguire S,Pezzella F,Banham AH,Li D
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Wed Sep 29 00:00:00 EDT 2021
Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist.
eLife
Glassman CR,Su L,Majri-Morrison SS,Winkelmann H,Mo F,Li P,Pérez-Cruz M,Ho PP,Koliesnik I,Nagy N,Hnizdilova T,Picton LK,Kovar M,Bollyky P,Steinman L,Meyer E,Piehler J,Leonard WJ,Garcia KC
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Tue May 18 00:00:00 EDT 2021
Transdifferentiation of tumor infiltrating innate lymphoid cells during progression of colorectal cancer.
Cell research
Wang S,Qu Y,Xia P,Chen Y,Zhu X,Zhang J,Wang G,Tian Y,Ying J,Fan Z
16-0193-81 was used in Flow Cytometry to profile tumor infiltrating innate lymphoid cells in colorectal cancer at early and late stages.
Wed Jul 01 00:00:00 EDT 2020
Excessive Costimulation Leads to Dysfunction of Adoptively Transferred T Cells.
Cancer immunology research
Wijewarnasuriya D,Bebernitz C,Lopez AV,Rafiq S,Brentjens RJ
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2020
Secreted Phospholipase A2 Group X Acts as an Adjuvant for Type 2 Inflammation, Leading to an Allergen-Specific Immune Response in the Lung.
Journal of immunology (Baltimore, Md. : 1950)
Ogden HL,Lai Y,Nolin JD,An D,Frevert CW,Gelb MH,Altemeier WA,Hallstrand TS
16-0193-81 was used in Flow Cytometry to demonstrate that exogenous and endogenous sPLA2s play an important role in peripheral sensitization, resulting in airway responses to inhaled Ags.
Mon Jun 15 00:00:00 EDT 2020
Differentiation Potential of Early- and Late-Passage Adipose-Derived Mesenchymal Stem Cells Cultured under Hypoxia and Normoxia.
Stem cells international
Zhao AG,Shah K,Freitag J,Cromer B,Sumer H
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Tue Oct 06 00:00:00 EDT 2020
Zdhhc2 Is Essential for Plasmacytoid Dendritic Cells Mediated Inflammatory Response in Psoriasis.
Frontiers in immunology
Zhou B,Yang W,Li W,He L,Lu L,Zhang L,Liu Z,Wang Y,Chao T,Huang R,Gu Y,Jia T,Liu Q,Tian S,Pierre P,Maeda T,Liang Y,Kong E
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Wed Jun 23 00:00:00 EDT 2021
CNS Immune Profiling in a Dengue Virus-Infected Immunocompetent Outbred ICR Mice Strain.
Frontiers in cellular and infection microbiology
Shen TJ,Chen CL,Jhan MK,Tseng PC,Lin CF
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Thu Jun 17 00:00:00 EDT 2021
Memory CD73+IgM+ B cells protect against Plasmodium yoelii infection and express Granzyme B.
PloS one
Parra M,Weitner M,Yang A,Akue A,Liu X,Schmidt T,Allman WR,Akkoyunlu M,Derrick SC
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Tue Oct 27 00:00:00 EDT 2020
Analysis of Myeloid Cells in Mouse Tissues with Flow Cytometry.
STAR protocols
Liu Z,Gu Y,Shin A,Zhang S,Ginhoux F
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Fri Jun 19 00:00:00 EDT 2020
Increased FGF-23 levels are linked to ineffective erythropoiesis and impaired bone mineralization in myelodysplastic syndromes.
JCI insight
Weidner H,Baschant U,Lademann F,Ledesma Colunga MG,Balaian E,Hofbauer C,Misof BM,Roschger P,Blouin S,Richards WG,Platzbecker U,Hofbauer LC,Rauner M
16-0193-81 was used in Flow Cytometry to identify FGF-23 as a link between altered bone structure and ineffective erythropoiesis in MDS with the prospects of a targeted therapeutic intervention.
Thu Aug 06 00:00:00 EDT 2020
Tregitopes regulate the tolerogenic immune response and decrease the foetal death rate in abortion-prone mouse matings.
Scientific reports
Kedzierska AE,Lorek D,Slawek A,Chelmonska-Soyta A
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Mon Jun 29 00:00:00 EDT 2020
The complex of MCMV proteins and MHC class I evades NK cell control and drives the evolution of virus-specific activating Ly49 receptors.
The Journal of experimental medicine
Železnjak J,Lisnić VJ,Popović B,Lisnić B,Babić M,Halenius A,L'Hernault A,Roviš TL,Hengel H,Erhard F,Redwood AJ,Vidal SM,Dölken L,Krmpotić A,Jonjić S
16-0193 was used in Flow cytometry/Cell sorting to solve a long-standing conundrum of how MCMV avoids recognition by NK cells, unravels a fundamental new viral immune evasion mechanism, and demonstrates how this forced the evolution of virus-specific activating MHC I-restricted Ly49 receptors.
Mon Aug 05 00:00:00 EDT 2019
Decreased immunoglobulin G in brain regions of elder female APOE4-TR mice accompany with Aβ accumulation.
Immunity & ageing : I & A
Zhang L,Xu J,Gao J,Chen P,Yin M,Zhao W
16-0193-81 was used in Flow Cytometry to determine the alterations of IgG, CD19, and Aβ in various brain regions of uninfected male and female APOE3- and APOE4-TR mice at the age of 3 and 10 months to elucidate impacts of AD risk factors on alterations of brain IgG.
Thu Mar 31 00:00:00 EDT 2022
NLRX1 inhibits the early stages of CNS inflammation and prevents the onset of spontaneous autoimmunity.
PLoS biology
Gharagozloo M,Mahmoud S,Simard C,Yamamoto K,Bobbala D,Ilangumaran S,Smith MD,Lamontagne A,Jarjoura S,Denault JB,Blais V,Gendron L,Vilariño-Güell C,Sadovnick AD,Ting JP,Calabresi PA,Amrani A,Gris D
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Sun Sep 01 00:00:00 EDT 2019
miR-181a/b-1 controls thymic selection of Treg cells and tunes their suppressive capacity.
PLoS biology
Łyszkiewicz M,Winter SJ,Witzlau K,Föhse L,Brownlie R,Puchałka J,Verheyden NA,Kunze-Schumacher H,Imelmann E,Blume J,Raha S,Sekiya T,Yoshimura A,Frueh JT,Ullrich E,Huehn J,Weiss S,Gutierrez MG,Prinz I,Zamoyska R,Ziętara N,Krueger A
16-0193-81 was used in Flow Cytometry to propose that intrathymic miR-181a/b-1 controls development of Treg cells and imposes a developmental legacy on their peripheral function.
Fri Mar 01 00:00:00 EST 2019
Distinct Requirements of CHD4 during B Cell Development and Antibody Response.
Cell reports
Yen WF,Sharma R,Cols M,Lau CM,Chaudhry A,Chowdhury P,Yewdell WT,Vaidyanathan B,Sun A,Coffre M,Pucella JN,Chen CC,Jasin M,Sun JC,Rudensky AY,Koralov SB,Chaudhuri J
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Tue Apr 30 00:00:00 EDT 2019
Peritoneal Cells Mediate Immune Responses and Cross-Protection Against Influenza A Virus.
Frontiers in immunology
Gautam A,Park BK,Kim TH,Akauliya M,Kim D,Maharjan S,Park J,Kim J,Lee H,Park MS,Lee Y,Kwon HJ
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Mon Aug 17 00:00:00 EDT 2020
The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes.
Nature communications
Luu M,Pautz S,Kohl V,Singh R,Romero R,Lucas S,Hofmann J,Raifer H,Vachharajani N,Carrascosa LC,Lamp B,Nist A,Stiewe T,Shaul Y,Adhikary T,Zaiss MM,Lauth M,Steinhoff U,Visekruna A
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Fri Feb 15 00:00:00 EST 2019
Variation in zygotic CRISPR/Cas9 gene editing outcomes generates novel reporter and deletion alleles at the Gdf11 locus.
Scientific reports
Goldstein JM,Valido A,Lewandowski JP,Walker RG,Mills MJ,Messemer KA,Besseling P,Lee KH,Wattrus SJ,Cho M,Lee RT,Wagers AJ
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Mon Dec 09 00:00:00 EST 2019
Inducible IL-7 Hyperexpression Influences Lymphocyte Homeostasis and Function and Increases Allograft Rejection.
Frontiers in immunology
Schreiber M,Weigelt M,Karasinsky A,Anastassiadis K,Schallenberg S,Petzold C,Bonifacio E,Kretschmer K,Hommel A
16-0193 was used in Flow cytometry/Cell sorting to show that transient hyperexpression of IL-7 can impair immune regulation, through disturbances in lymphocyte development pathways, and decrease graft survival time, even under immunosuppression.
Mon Sep 14 00:00:00 EDT 2020
Critical role of post-transcriptional regulation for IFN-γ in tumor-infiltrating T cells.
Oncoimmunology
Salerno F,Guislain A,Freen-Van Heeren JJ,Nicolet BP,Young HA,Wolkers MC
16-0193 was used in Flow cytometry/Cell sorting to conclude that post-transcriptional mechanisms could be modulated to potentiate effective T cell therapies in cancer.
Tue Jan 12 00:00:00 EST 2021
Female and male mouse lung group 2 innate lymphoid cells differ in gene expression profiles and cytokine production.
PloS one
Mathä L,Shim H,Steer CA,Yin YH,Martinez-Gonzalez I,Takei F
16-0193-81 was used in Flow Cytometry to suggest that female ILC2s are more readily activated than male ILC2s due to their gene expression at the naïve state, which is potentially influenced by the lung environment.
Mon Dec 16 00:00:00 EST 2019
CXCR5-negative natural killer cells ameliorate experimental autoimmune myasthenia gravis by suppressing follicular helper T cells.
Journal of neuroinflammation
Yang CL,Zhang P,Liu RT,Zhang N,Zhang M,Li H,Du T,Li XL,Dou YC,Duan RS
16-0193-81 was used in Flow Cytometry to investigate the function of NK cells in experimental autoimmune myasthenia gravis in vivo.
Sun Dec 29 00:00:00 EST 2019
Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.
Cell
Gaya M,Barral P,Burbage M,Aggarwal S,Montaner B,Warren Navia A,Aid M,Tsui C,Maldonado P,Nair U,Ghneim K,Fallon PG,Sekaly RP,Barouch DH,Shalek AK,Bruckbauer A,Strid J,Batista FD
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Thu Jan 25 00:00:00 EST 2018
TET2 Deficiency Causes Germinal Center Hyperplasia, Impairs Plasma Cell Differentiation, and Promotes B-cell Lymphomagenesis.
Cancer discovery
Dominguez PM,Ghamlouch H,Rosikiewicz W,Kumar P,Béguelin W,Fontán L,Rivas MA,Pawlikowska P,Armand M,Mouly E,Torres-Martin M,Doane AS,Calvo Fernandez MT,Durant M,Della-Valle V,Teater M,Cimmino L,Droin N,Tadros S,Motanagh S,Shih AH,Rubin MA,Tam W,Aifantis I,Levine RL,Elemento O,Inghirami G,Green MR,Figueroa ME,Bernard OA,Aoufouchi S,Li S,Shaknovich R,Melnick AM
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Sat Dec 01 00:00:00 EST 2018
11 Beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis.
Journal of autoimmunity
Hardy RS,Fenton C,Croft AP,Naylor AJ,Begum R,Desanti G,Buckley CD,Lavery G,Cooper MS,Raza K
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Wed Aug 01 00:00:00 EDT 2018
Transforming Growth Factor-β and Interleukin-10 Synergistically Regulate Humoral Immunity via Modulating Metabolic Signals.
Frontiers in immunology
Komai T,Inoue M,Okamura T,Morita K,Iwasaki Y,Sumitomo S,Shoda H,Yamamoto K,Fujio K
16-0193 was used in Flow cytometry/Cell sorting to study the requirement of a combination of TGF-β and IL-10 to suppress B cell activation induced by toll-like receptor stimulation.
Wed Nov 20 00:00:00 EST 2019
Inactivation of mTORC1 Signaling in Osterix-Expressing Cells Impairs B-cell Differentiation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Wang Y,Xiao M,Tao C,Chen J,Wang Z,Yang J,Chen Z,Zou Z,Liu A,Cai D,Jiang Y,Ding C,Li M,Bai X
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2018
The Role of Allograft Inflammatory Factor-1 in the Effects of Experimental Diabetes on B Cell Functions in the Heart.
Frontiers in cardiovascular medicine
Sarkar A,Shukla SK,Alqatawni A,Kumar A,Addya S,Tsygankov AY,Rafiq K
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Mon Dec 06 00:00:00 EST 2021
The Role of Allograft Inflammatory Factor-1 in the Effects of Experimental Diabetes on B Cell Functions in the Heart.
Frontiers in cardiovascular medicine
Sarkar A,Shukla SK,Alqatawni A,Kumar A,Addya S,Tsygankov AY,Rafiq K
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Mon Dec 06 00:00:00 EST 2021
CD22 Promotes B-1b Cell Responses to T Cell-Independent Type 2 Antigens.
Journal of immunology (Baltimore, Md. : 1950)
Haas KM,Johnson KL,Phipps JP,Do C
16-0193 was used in Flow cytometry/Cell sorting to demonstrate CD22 plays a critical role in regulating T cell-independent type 2 antibody responses through regulating B-1b cell signaling thresholds.
Thu Mar 01 00:00:00 EST 2018
Multiple Levels of Control Determine How E4bp4/Nfil3 Regulates NK Cell Development.
Journal of immunology (Baltimore, Md. : 1950)
Kostrzewski T,Borg AJ,Meng Y,Filipovic I,Male V,Wack A,DiMaggio PA,Brady HJM
16-0193 was used in Flow cytometry/Cell sorting to reveal mechanisms in NK cell development and that E4bp4 is a central hub to process extrinsic stimuli.
Thu Feb 15 00:00:00 EST 2018
In Vitro Differentiation of Gata2 and Ly6a Reporter Embryonic Stem Cells Corresponds to In Vivo Waves of Hematopoietic Cell Generation.
Stem cell reports
Kauts ML,Rodriguez-Seoane C,Kaimakis P,Mendes SC,Cortés-Lavaud X,Hill U,Dzierzak E
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Tue Jan 09 00:00:00 EST 2018
Peli1 negatively regulates noncanonical NF-κB signaling to restrain systemic lupus erythematosus.
Nature communications
Liu J,Huang X,Hao S,Wang Y,Liu M,Xu J,Zhang X,Yu T,Gan S,Dai D,Luo X,Lu Q,Mao C,Zhang Y,Shen N,Li B,Huang M,Zhu X,Jin J,Cheng X,Sun SC,Xiao Y
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Mon Mar 19 00:00:00 EDT 2018
Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus.
eLife
Moretti FA,Klapproth S,Ruppert R,Margraf A,Weber J,Pick R,Scheiermann C,Sperandio M,Fässler R,Moser M
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Thu Sep 06 00:00:00 EDT 2018
A protocol for generating induced T cells by reprogramming B cells in vivo.
Cell regeneration (London, England)
Weng Q,Hu F,Zhang M,Dong Y,Lv C,Wang Y,Liu X,Wang J
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2018
A disconnect between precursor frequency, expansion potential, and site-specific CD4+ T cell responses in aged mice.
PloS one
Deshpande NR,Uhrlaub JL,Way SS,Nikolich-Žugich J,Kuhns MS
16-0193 was used in functional assays to explore if CD4+ T cell responses to immunization or infection increase with aging.
Tue Dec 11 00:00:00 EST 2018
Adipose tissue B2 cells promote insulin resistance through leukotriene LTB4/LTB4R1 signaling.
The Journal of clinical investigation
Ying W,Wollam J,Ofrecio JM,Bandyopadhyay G,El Ouarrat D,Lee YS,Oh DY,Li P,Osborn O,Olefsky JM
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
A therapeutic T cell receptor mimic antibody targets tumor-associated PRAME peptide/HLA-I antigens.
The Journal of clinical investigation
Chang AY,Dao T,Gejman RS,Jarvis CA,Scott A,Dubrovsky L,Mathias MD,Korontsvit T,Zakhaleva V,Curcio M,Hendrickson RC,Liu C,Scheinberg DA
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Fri Jun 30 00:00:00 EDT 2017
Dissection of SAP-dependent and SAP-independent SLAM family signaling in NKT cell development and humoral immunity.
The Journal of experimental medicine
Chen S,Cai C,Li Z,Liu G,Wang Y,Blonska M,Li D,Du J,Lin X,Yang M,Dong Z
16-0193-81 was used in Flow Cytometry to examine NKT cell development and humoral immunity in mice completely deficient in SFR.
Wed Feb 01 00:00:00 EST 2017
CD73 regulates anti-inflammatory signaling between apoptotic cells and endotoxin-conditioned tissue macrophages.
Cell death and differentiation
Murphy PS,Wang J,Bhagwat SP,Munger JC,Janssen WJ,Wright TW,Elliott MR
16-0193 was used in Flow cytometry/Cell sorting to show that, in RAW264.7 cells, ectopic expression of both A2a and CD73 was required for TNF suppression by apoptotic cells.
Wed Mar 01 00:00:00 EST 2017
Prolonged Deleterious Influences of Chemotherapeutic Agent CPT-11 on Resident Peritoneal Macrophages and B1 Cells.
Frontiers in immunology
Bai WJ,Li CG,Zhang CC,Xu LH,Zeng QZ,Hu B,Hong Z,He XH,Ouyang DY
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
NCR1-deficiency diminishes the generation of protective murine cytomegalovirus antibodies by limiting follicular helper T-cell maturation.
European journal of immunology
Miletic A,Lenartic M,Popovic B,Brizic I,Trsan T,Miklic K,Mandelboim O,Krmpotic A,Jonjic S
16-0193 was used in Flow cytometry/Cell sorting to provide evidence for the role of NCR1 in antibody response to mouse cytomegalovirus infection.
Fri Sep 01 00:00:00 EDT 2017
ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis.
RNA biology
Ben-Shoshan SO,Kagan P,Sultan M,Barabash Z,Dor C,Jacob-Hirsch J,Harmelin A,Pappo O,Marcu-Malina V,Ben-Ari Z,Amariglio N,Rechavi G,Goldstein I,Safran M
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Thu May 04 00:00:00 EDT 2017
Diminished bone regeneration after debridement of posttraumatic osteomyelitis is accompanied by altered cytokine levels, elevated B cell activity, and increased osteoclast activity.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Wagner JM,Jaurich H,Wallner C,Abraham S,Becerikli M,Dadras M,Harati K,Duhan V,Khairnar V,Lehnhardt M,Behr B
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Wed Nov 01 00:00:00 EDT 2017
Intravenously usable fully serotype 3 oncolytic adenovirus coding for CD40L as an enabler of dendritic cell therapy.
Oncoimmunology
Zafar S,Parviainen S,Siurala M,Hemminki O,Havunen R,Tähtinen S,Bramante S,Vassilev L,Wang H,Lieber A,Hemmi S,de Gruijl T,Kanerva A,Hemminki A
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.
Nature communications
Deng R,Hurtz C,Song Q,Yue C,Xiao G,Yu H,Wu X,Muschen M,Forman S,Martin PJ,Zeng D
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Tue Oct 17 00:00:00 EDT 2017
Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.
Nature communications
Deng R,Hurtz C,Song Q,Yue C,Xiao G,Yu H,Wu X,Muschen M,Forman S,Martin PJ,Zeng D
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Tue Oct 17 00:00:00 EDT 2017
WASH maintains NKp46+ ILC3 cells by promoting AHR expression.
Nature communications
Xia P,Liu J,Wang S,Ye B,Du Y,Xiong Z,Han ZG,Tong L,Fan Z
16-0193 was used in Flow cytometry/Cell sorting to study how WASH-mediated AHR expression has a critical function in the maintenance of NKp46(+) ILC3s.
Wed Jun 07 00:00:00 EDT 2017
Human and Mouse Hematopoietic Stem Cells Are a Depot for Dormant Mycobacterium tuberculosis.
PloS one
Tornack J,Reece ST,Bauer WM,Vogelzang A,Bandermann S,Zedler U,Stingl G,Kaufmann SH,Melchers F
16-0193-81 was used in Flow Cytometry to conclude that LT-pHSCs, together with MSCs of Mtb-infected humans and mice serve as a hitherto unappreciated quiescent cellular depot for Mtb during latent TB infection.
Tue Sep 05 00:00:00 EDT 2017
Calreticulin promotes immunity and type I interferon-dependent survival in mice with acute myeloid leukemia.
Oncoimmunology
Chen X,Fosco D,Kline DE,Kline J
16-0193 was used in Flow cytometry/Cell sorting to determine the effect of calreticulin on cancer cell phagocytosis on tumour immunity.
Tue Jan 12 00:00:00 EST 2021
IL35-Producing B Cells Promote the Development of Pancreatic Neoplasia.
Cancer discovery
Pylayeva-Gupta Y,Das S,Handler JS,Hajdu CH,Coffre M,Koralov SB,Bar-Sagi D
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation.
Nature immunology
Monticelli LA,Buck MD,Flamar AL,Saenz SA,Tait Wojno ED,Yudanin NA,Osborne LC,Hepworth MR,Tran SV,Rodewald HR,Shah H,Cross JR,Diamond JM,Cantu E,Christie JD,Pearce EL,Artis D
16-0193 was used in Flow cytometry/Cell sorting to identify Arg1 as a key regulator of group 2 innate lymphoid cell bioenergetics that control proliferative capacity and pro-inflammatory functions.
Wed Jun 01 00:00:00 EDT 2016
Medial HOXA genes demarcate haematopoietic stem cell fate during human development.
Nature cell biology
Dou DR,Calvanese V,Sierra MI,Nguyen AT,Minasian A,Saarikoski P,Sasidharan R,Ramirez CM,Zack JA,Crooks GM,Galic Z,Mikkola HK
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Wed Jun 01 00:00:00 EDT 2016
Tetraspanin CD37 protects against the development of B cell lymphoma.
The Journal of clinical investigation
de Winde CM,Veenbergen S,Young KH,Xu-Monette ZY,Wang XX,Xia Y,Jabbar KJ,van den Brand M,van der Schaaf A,Elfrink S,van Houdt IS,Gijbels MJ,van de Loo FA,Bennink MB,Hebeda KM,Groenen PJ,van Krieken JH,Figdor CG,van Spriel AB
16-0193 was used in Immunohistochemistry to show that CD37 deficiency drives B cell lymphomagenesis through constitutive activation of the IL-6 pathway, highlighting a possible therapeutic intervention.
Mon Feb 01 00:00:00 EST 2016
Molecular requirements of the B-cell antigen receptor for sensing monovalent antigens.
The EMBO journal
Volkmann C,Brings N,Becker M,Hobeika E,Yang J,Reth M
16-0193 was used in Flow cytometry/Cell sorting to study the effects of differing monovalent stimuli on B-cell antigen receptor signalling and organisation.
Wed Nov 02 00:00:00 EDT 2016
Antigen Targeting to Human HLA Class II Molecules Increases Efficacy of DNA Vaccination.
Journal of immunology (Baltimore, Md. : 1950)
Grodeland G,Fredriksen AB,Løset GÅ,Vikse E,Fugger L,Bogen B
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2016
Survival of Igα-Deficient Mature B Cells Requires BAFF-R Function.
Journal of immunology (Baltimore, Md. : 1950)
Levit-Zerdoun E,Becker M,Pohlmeyer R,Wilhelm I,Maity PC,Rajewsky K,Reth M,Hobeika E
16-0193 was used in Flow cytometry/Cell sorting to assess the importance of the expression of a functional B-cell receptor for B cell maintenance.
Tue Mar 01 00:00:00 EST 2016
CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity.
Nature communications
Jacoby E,Nguyen SM,Fountaine TJ,Welp K,Gryder B,Qin H,Yang Y,Chien CD,Seif AE,Lei H,Song YK,Khan J,Lee DW,Mackall CL,Gardner RA,Jensen MC,Shern JF,Fry TJ
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Wed Jul 27 00:00:00 EDT 2016
Novel CXCL13 transgenic mouse: inflammation drives pathogenic effect of CXCL13 in experimental myasthenia gravis.
Oncotarget
Weiss JM,Robinet M,Aricha R,Cufi P,Villeret B,Lantner F,Shachar I,Fuchs S,Souroujon MC,Berrih-Aknin S,Le Panse R
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Tue Feb 16 00:00:00 EST 2016
Protein Kinase D2 Protects against Acute Colitis Induced by Dextran Sulfate Sodium in Mice.
Scientific reports
Xiong J,Zhou MF,Wang YD,Chen LP,Xu WF,Wang YD,Deng F,Liu SD
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Fri Sep 23 00:00:00 EDT 2016
CRISPR-Mediated Triple Knockout of SLAMF1, SLAMF5 and SLAMF6 Supports Positive Signaling Roles in NKT Cell Development.
PloS one
Huang B,Gomez-Rodriguez J,Preite S,Garrett LJ,Harper UL,Schwartzberg PL
16-0193 was used in Flow cytometry/Cell sorting to elucidate the contribution of the SLAM receptors in immunodysregulation observed in X-linked lymphoproliferative syndrome Type 1.
Mon Jul 24 00:00:00 EDT 2017
OASL1 deficiency promotes antiviral protection against genital herpes simplex virus type 2 infection by enhancing type I interferon production.
Scientific reports
Oh JE,Lee MS,Kim YJ,Lee HK
16-0193 was used in Flow cytometry/Cell sorting to investigate the role of 2'-5' oligoadenylate synthetase-like 1 (OASL1) during localised viral infection in mice.
Mon Jan 11 00:00:00 EST 2016
PKR is not obligatory for high-fat diet-induced obesity and its associated metabolic and inflammatory complications.
Nature communications
Lancaster GI,Kammoun HL,Kraakman MJ,Kowalski GM,Bruce CR,Febbraio MA
16-0193 was used in Flow cytometry/Cell sorting to examine the role of protein kinase R in the development of obesity and its associated metabolic complications in vivo as well as its putative lipid-sensing role in vitro.
Wed Feb 03 00:00:00 EST 2016
Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease.
Blood
Flynn R,Allen JL,Luznik L,MacDonald KP,Paz K,Alexander KA,Vulic A,Du J,Panoskaltsis-Mortari A,Taylor PA,Poe JC,Serody JS,Murphy WJ,Hill GR,Maillard I,Koreth J,Cutler CS,Soiffer RJ,Antin JH,Ritz J,Chao NJ,Clynes RA,Sarantopoulos S,Blazar BR
16-0193 was used in Flow cytometry/Cell sorting to further evaluate the role of the spleen tyrosine kinase in graft-versus-host disease in multiple murine models and human peripheral blood cells.
Thu Jun 25 00:00:00 EDT 2015
Bcl11b is essential for group 2 innate lymphoid cell development.
The Journal of experimental medicine
Walker JA,Oliphant CJ,Englezakis A,Yu Y,Clare S,Rodewald HR,Belz G,Liu P,Fallon PG,McKenzie AN
16-0193 was used in Flow cytometry/Cell sorting to study the role of Bcl11b in the differentiation of group 2 innate lymphoid cells.
Mon Jun 01 00:00:00 EDT 2015
Cis-regulatory mechanisms governing stem and progenitor cell transitions.
Science advances
Johnson KD,Kong G,Gao X,Chang YI,Hewitt KJ,Sanalkumar R,Prathibha R,Ranheim EA,Dewey CN,Zhang J,Bresnick EH
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
IL-4 Induced Innate CD8+ T Cells Control Persistent Viral Infection.
PLoS pathogens
Lee A,Park SP,Park CH,Kang BH,Park SH,Ha SJ,Jung KC
16-0193 was used in Flow cytometry/Cell sorting to investigate the mechanism by which IL-4-induced innate CD8+ T cells control chronic virus infection.
Thu Oct 01 00:00:00 EDT 2015
Role of caveolin-3 in lymphocyte activation.
Life sciences
Tran C,Stary CM,Schilling JM,Bentley B,Patel HH,Roth DM
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Thu Jan 15 00:00:00 EST 2015
Role of type I interferon signaling in human metapneumovirus pathogenesis and control of viral replication.
Journal of virology
Hastings AK,Erickson JJ,Schuster JE,Boyd KL,Tollefson SJ,Johnson M,Gilchuk P,Joyce S,Williams JV
16-0193 was used in Flow cytometry/Cell sorting to assess the effect of alpha interferon receptor signalling on human metapneumovirus replication and the CD8(+) T cell response.
Wed Apr 01 00:00:00 EDT 2015
B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses.
Journal of immunology (Baltimore, Md. : 1950)
Pone EJ,Lam T,Lou Z,Wang R,Chen Y,Liu D,Edinger AL,Xu Z,Casali P
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
Natural IgM Switches the Function of Lipopolysaccharide-Activated Murine Bone Marrow-Derived Dendritic Cells to a Regulatory Dendritic Cell That Suppresses Innate Inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Lobo PI,Schlegel KH,Bajwa A,Huang L,Kurmaeva E,Wang B,Ye H,Tedder TF,Kinsey GR,Okusa MD
16-0193 was used in Flow cytometry/Cell sorting to investigate how natural IgM anti-leukocyte Abs can switch BMDC to a regulatory phenotype despite the presence of LPS that ordinarily induces BMDC maturation.
Tue Dec 01 00:00:00 EST 2015
Mouse bone marrow-derived mesenchymal stem cells inhibit leukemia/lymphoma cell proliferation in vitro and in a mouse model of allogeneic bone marrow transplant.
International journal of molecular medicine
Song N,Gao L,Qiu H,Huang C,Cheng H,Zhou H,Lv S,Chen L,Wang J
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2015
The B subunit of Escherichia coli heat-labile toxin alters the development and antigen-presenting capacity of dendritic cells.
Journal of cellular and molecular medicine
Ji J,Griffiths KL,Milburn PJ,Hirst TR,O'Neill HC
16-0193 was used in Magnetic cell separation to investigate the direct effect of intravenously administered EtxB on the size of the dendritic and myeloid cell populations in spleen.
Sat Aug 01 00:00:00 EDT 2015
dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis.
Nature communications
Lim S,Kim WJ,Kim YH,Lee S,Koo JH,Lee JA,Yoon H,Kim DH,Park HJ,Kim HM,Lee HG,Yun Kim J,Lee JU,Hun Shin J,Kyun Kim L,Doh J,Kim H,Lee SK,Bothwell ALM,Suh M,Choi JM
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Tue Sep 15 00:00:00 EDT 2015
Immunostimulatory Effects Triggered by Enterococcus faecalis CECT7121 Probiotic Strain Involve Activation of Dendritic Cells and Interferon-Gamma Production.
PloS one
Molina MA,Díaz AM,Hesse C,Ginter W,Gentilini MV,Nuñez GG,Canellada AM,Sparwasser T,Berod L,Castro MS,Manghi MA
16-0193 was used in Flow cytometry/Cell sorting to elucidate the influence of E. faecalis CECT7121 on dendritic cells and the outcome of the immune responses.
Tue Apr 19 00:00:00 EDT 2016
Splenic red pulp macrophages are intrinsically superparamagnetic and contaminate magnetic cell isolates.
Scientific reports
Franken L,Klein M,Spasova M,Elsukova A,Wiedwald U,Welz M,Knolle P,Farle M,Limmer A,Kurts C
16-0193 was used in Flow cytometry/Cell sorting to elucidate the intrinsic superparamagnetic nature of splenic red pulp macrophages and their effect on magnetic cell isolates.
Tue Aug 11 00:00:00 EDT 2015
Gammaherpesvirus small noncoding RNAs are bifunctional elements that regulate infection and contribute to virulence in vivo.
mBio
Diebel KW,Oko LM,Medina EM,Niemeyer BF,Warren CJ,Claypool DJ,Tibbetts SA,Cool CD,Clambey ET,van Dyk LF
16-0193 was used in Flow cytometry/Cell sorting to show that herpesvirus ncRNAs play critical roles in acute infection and virulence in immunocompromised hosts.
Tue Feb 17 00:00:00 EST 2015
The transcription factor E4bp4/Nfil3 controls commitment to the NK lineage and directly regulates Eomes and Id2 expression.
The Journal of experimental medicine
Male V,Nisoli I,Kostrzewski T,Allan DS,Carlyle JR,Lord GM,Wack A,Brady HJ
16-0193 was used in Flow cytometry/Cell sorting to propose that E4bp4 is required for commitment to the NK lineage and can promote NK development by directly regulating the expression of the downstream transcription factors Eomes and Id2.
Mon Apr 07 00:00:00 EDT 2014
Regulation of germinal center responses and B-cell memory by the chromatin modifier MOZ.
Proceedings of the National Academy of Sciences of the United States of America
Good-Jacobson KL,Chen Y,Voss AK,Smyth GK,Thomas T,Tarlinton D
16-0193 was used in Flow cytometry/Cell sorting to provide evidence that manipulating epigenetic modifiers can regulate fate decisions during humoral responses.
Tue Jul 01 00:00:00 EDT 2014
Invariant natural killer T cells act as an extravascular cytotoxic barrier for joint-invading Lyme Borrelia.
Proceedings of the National Academy of Sciences of the United States of America
Lee WY,Sanz MJ,Wong CH,Hardy PO,Salman-Dilgimen A,Moriarty TJ,Chaconas G,Marques A,Krawetz R,Mody CH,Kubes P
16-0193 was used in Flow cytometry/Cell sorting to demonstrate a novel, critical extravascular invariant natural killer T cell-mediated mechanism of immune surveillance in joints.
Tue Sep 23 00:00:00 EDT 2014
STING contributes to antiglioma immunity via triggering type I IFN signals in the tumor microenvironment.
Cancer immunology research
Ohkuri T,Ghosh A,Kosaka A,Zhu J,Ikeura M,David M,Watkins SC,Sarkar SN,Okada H
16-0193 was used in Flow cytometry/Cell sorting to display a potential use of STING agonists for the development of effective immunotherapy.
Mon Dec 01 00:00:00 EST 2014
Few Foxp3⁺ regulatory T cells are sufficient to protect adult mice from lethal autoimmunity.
European journal of immunology
Mayer CT,Ghorbani P,Kühl AA,Stüve P,Hegemann M,Berod L,Gershwin ME,Sparwasser T
16-0193 was used in Flow cytometry/Cell sorting to study the mechanisms underlying why regulatory T cell-depletion fails to cause autoimmunity in adult Depletion of REGulatory T cells mice.
Wed Oct 01 00:00:00 EDT 2014
Characterization of conventional and atypical receptors for the chemokine CCL2 on mouse leukocytes.
Journal of immunology (Baltimore, Md. : 1950)
Ford LB,Cerovic V,Milling SW,Graham GJ,Hansell CA,Nibbs RJ
16-0193 was used in Flow cytometry/Cell sorting to define the expression profile, scavenging activity, and ligand specificity of CCL2 receptors on mouse leukocytes.
Tue Jul 01 00:00:00 EDT 2014
The DC-HIL/syndecan-4 pathway regulates autoimmune responses through myeloid-derived suppressor cells.
Journal of immunology (Baltimore, Md. : 1950)
Chung JS,Tamura K,Akiyoshi H,Cruz PD,Ariizumi K
16-0193 was used in Flow cytometry/Cell sorting to investigate the mechanisms of regulation of autoimmune responses in experimental autoimmune encephalomyelitis.
Sat Mar 15 00:00:00 EDT 2014
Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells.
eLife
Sojka DK,Plougastel-Douglas B,Yang L,Pak-Wittel MA,Artyomov MN,Ivanova Y,Zhong C,Chase JM,Rothman PB,Yu J,Riley JK,Zhu J,Tian Z,Yokoyama WM
16-0193 was used in Flow cytometry/Cell sorting to investigate whether tissue-resident and cells resembling conventional splenic natural killer cells natural killer cells are derived from the same lineage, showing that there are at least four distinct lineages.
Wed Jan 01 00:00:00 EST 2014
Intraperitoneal prophylaxis with CpG oligodeoxynucleotides protects neutropenic mice against intracerebral Escherichia coli K1 infection.
Journal of neuroinflammation
Ribes S,Meister T,Ott M,Redlich S,Janova H,Hanisch UK,Nessler S,Nau R
16-0193 was used in Flow cytometry/Cell sorting to suggest that systemic administration of CpG ODN may help to prevent bacterial CNS infections in immunocompromised individuals.
Thu Jan 23 00:00:00 EST 2014
T cell factor 1 is required for group 2 innate lymphoid cell generation.
Immunity
Yang Q,Monticelli LA,Saenz SA,Chi AW,Sonnenberg GF,Tang J,De Obaldia ME,Bailis W,Bryson JL,Toscano K,Huang J,Haczku A,Pear WS,Artis D,Bhandoola A
16-0193 was used in Flow cytometry/Cell sorting to study group 2 innate lymphoid cell development.
Thu Apr 18 00:00:00 EDT 2013
Nrf2 regulates haematopoietic stem cell function.
Nature cell biology
Tsai JJ,Dudakov JA,Takahashi K,Shieh JH,Velardi E,Holland AM,Singer NV,West ML,Smith OM,Young LF,Shono Y,Ghosh A,Hanash AM,Tran HT,Moore MA,van den Brink MR
16-0193 was used in Flow cytometry/Cell sorting to investigate the link between Nrf2 and CXCR4, thought to partially contribute to the maintenance of haematopoietic stem cell function.
Fri Mar 01 00:00:00 EST 2013
HIF prolyl hydroxylase 2 (PHD2) is a critical regulator of hematopoietic stem cell maintenance during steady-state and stress.
Blood
Singh RP,Franke K,Kalucka J,Mamlouk S,Muschter A,Gembarska A,Grinenko T,Willam C,Naumann R,Anastassiadis K,Stewart AF,Bornstein S,Chavakis T,Breier G,Waskow C,Wielockx B
16-0193 was used in Flow cytometry/Cell sorting to study the role of PHD2 in HSC compartment maintenance.
Thu Jun 27 00:00:00 EDT 2013
Gata2 cis-element is required for hematopoietic stem cell generation in the mammalian embryo.
The Journal of experimental medicine
Gao X,Johnson KD,Chang YI,Boyer ME,Dewey CN,Zhang J,Bresnick EH
16-0193 was used in Flow cytometry/Cell sorting to investigate the role of Gata2 cis-element in generation of hematopoietic stem cells.
Mon Dec 16 00:00:00 EST 2013
HDL and Glut1 inhibition reverse a hypermetabolic state in mouse models of myeloproliferative disorders.
The Journal of experimental medicine
Gautier EL,Westerterp M,Bhagwat N,Cremers S,Shih A,Abdel-Wahab O,Lütjohann D,Randolph GJ,Levine RL,Tall AR,Yvan-Charvet L
16-0193 was used in Flow cytometry/Cell sorting to investigate the underlying mechanisms leading to high metabolic rate in myeloproliferative disorders, showing that HDL and Glut1 inhibition reverse hypermetabolic state.
Mon Feb 11 00:00:00 EST 2013
An intact immune system is required for the anticancer activities of histone deacetylase inhibitors.
Cancer research
West AC,Mattarollo SR,Shortt J,Cluse LA,Christiansen AJ,Smyth MJ,Johnstone RW
16-0193 was used in Flow cytometry/Cell sorting to clarify the role of the immune system in mediating the efficacy of HDACi against tumours, showing that an intact immune system is required for anticancer activity.
Sun Dec 15 00:00:00 EST 2013
β-Arrestin-1 deficiency protects mice from experimental colitis.
The American journal of pathology
Lee T,Lee E,Irwin R,Lucas PC,McCabe LR,Parameswaran N
16-0193 was used in Flow cytometry/Cell sorting to demonstrate that altered interleukin production in β-arrestin-1-deficient mice likely leads to attenuated gut inflammation.
Mon Apr 01 00:00:00 EDT 2013
Programmed death receptor-1/programmed death receptor ligand-1 blockade after transient lymphodepletion to treat myeloma.
Journal of immunology (Baltimore, Md. : 1950)
Kearl TJ,Jing W,Gershan JA,Johnson BD
16-0193 was used in Flow cytometry/Cell sorting to demonstrate that a blockade of the PD-1/PD-L1 pathway yields positive antitumour results.
Sat Jun 01 00:00:00 EDT 2013
Temporal requirements for B cells in the establishment of CD4 T cell memory.
Journal of immunology (Baltimore, Md. : 1950)
Mollo SB,Zajac AJ,Harrington LE
16-0193 was used in Flow cytometry/Cell sorting to demonstrate the temporally and functionally distinct roles for B cells in regulating CD4 T cell responses.
Sun Dec 15 00:00:00 EST 2013
SAP modulates B cell functions in a genetic background-dependent manner.
Immunology letters
Detre C,Yigit B,Keszei M,Castro W,Magelky EM,Terhorst C
16-0193 was used in Flow cytometry/Cell sorting to investigate the mechanism by which SLAM-associated protein modulates B cell functions.
Sat Jun 01 00:00:00 EDT 2013
Deletion of Snai2 and Snai3 results in impaired physical development compounded by lymphocyte deficiency.
PloS one
Pioli PD,Dahlem TJ,Weis JJ,Weis JH
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Wed Feb 19 00:00:00 EST 2014
Dll4-Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice.
The Journal of experimental medicine
Billiard F,Lobry C,Darrasse-Jèze G,Waite J,Liu X,Mouquet H,DaNave A,Tait M,Idoyaga J,Leboeuf M,Kyratsous CA,Burton J,Kalter J,Klinakis A,Zhang W,Thurston G,Merad M,Steinman RM,Murphy AJ,Yancopoulos GD,Aifantis I,Skokos D
16-0193 was used in Flow cytometry/Cell sorting to investigate how Dll4-Notch signaling affects pro-T cell fate and thymic DC development, showing that it is a novel Flt3-independent pathway for DC development and autoimmunity.
Mon May 07 00:00:00 EDT 2012
A novel method for autophagy detection in primary cells: impaired levels of macroautophagy in immunosenescent T cells.
Autophagy
Phadwal K,Alegre-Abarrategui J,Watson AS,Pike L,Anbalagan S,Hammond EM,Wade-Martins R,McMichael A,Klenerman P,Simon AK
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2012
Lymphotoxin-beta receptor blockade induces inflammation and fibrosis in tolerized cardiac allografts.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Nakayama Y,Bromberg JS
16-0193 was used in Flow cytometry/Cell sorting to study the effect of LTβRIg treatment in a murine cardiac allograft model.
Sat Sep 01 00:00:00 EDT 2012
Critical role of B cell lymphoma 10 in BAFF-regulated NF-κB activation and survival of anergic B cells.
Journal of immunology (Baltimore, Md. : 1950)
Yu M,Chen Y,He Y,Podd A,Fu G,Wright JA,Kleiman E,Khan WN,Wen R,Wang D
Published figure using CD19 monoclonal antibody (Product # 16-0193-81) in Flow Cytometry
Sat Dec 01 00:00:00 EST 2012
Exposure to nicotine adversely affects the dendritic cell system and compromises host response to vaccination.
Journal of immunology (Baltimore, Md. : 1950)
Nouri-Shirazi M,Guinet E
16-0193 was used in Flow cytometry/Cell sorting to investigate the causal relationship between nicotine-induced dendritic cell alterations and host response to vaccines.
Thu Mar 01 00:00:00 EST 2012
Th2 type inflammation promotes the gradual progression of HPV-infected cervical cells to cervical carcinoma.
Gynecologic oncology
Feng Q,Wei H,Morihara J,Stern J,Yu M,Kiviat N,Hellstrom I,Hellstrom KE
16-0193 was used in Flow cytometry/Cell sorting to study the effect of Th2 inflammation upon the tumorigenesis of cervical cancer in human papillomavirus infected women.
Thu Nov 01 00:00:00 EDT 2012
Amniotic epithelial cells from the human placenta potently suppress a mouse model of multiple sclerosis.
PloS one
Liu YH,Vaghjiani V,Tee JY,To K,Cui P,Oh DY,Manuelpillai U,Toh BH,Chan J
16-0193 was used in Flow cytometry/Cell sorting to show that hAEC can significantly suppress splenocyte proliferation in vitro and attenuate a mouse model of multiple sclerosis.
Mon Sep 17 00:00:00 EDT 2012
The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-α receptor.
Nature immunology
Papadopoulou AS,Dooley J,Linterman MA,Pierson W,Ucar O,Kyewski B,Zuklys S,Hollander GA,Matthys P,Gray DH,De Strooper B,Liston A
16-0193 was used in Flow cytometry/Cell sorting to find that the microRNA network dependent on the endoribonuclease Dicer, was critical for diminishing the sensitivity of the thymic epithelium to simulated infection signals.
Sun Dec 18 00:00:00 EST 2011
Delivery of progenitors to the thymus limits T-lineage reconstitution after bone marrow transplantation.
Blood
Zlotoff DA,Zhang SL,De Obaldia ME,Hess PR,Todd SP,Logan TD,Bhandoola A
16-0193 was used in Flow cytometry/Cell sorting to explain why T cells are among the last of the hematopoietic lineages to recover after bone marrow transplantation (BMT).
Thu Aug 18 00:00:00 EDT 2011
Differential expression of NLRP3 among hematopoietic cells.
Journal of immunology (Baltimore, Md. : 1950)
Guarda G,Zenger M,Yazdi AS,Schroder K,Ferrero I,Menu P,Tardivel A,Mattmann C,Tschopp J
16-0193 was used in Flow cytometry/Cell sorting to characterize NOD-like receptor pyrin domain 3 (NLRP3) expression due to importance in health and disease.
Tue Feb 15 00:00:00 EST 2011
Leukocytes infiltrate the skin and draining lymph nodes in response to the protozoan Leishmania infantum chagasi.
Infection and immunity
Thalhofer CJ,Chen Y,Sudan B,Love-Homan L,Wilson ME
16-0193 was used in Flow cytometry/Cell sorting to define the inflammatory response at the Leishmania infantum chagasi parasite inoculation site.
Sat Jan 01 00:00:00 EST 2011
Notch dimerization is required for leukemogenesis and T-cell development.
Genes & development
Liu H,Chi AW,Arnett KL,Chiang MY,Xu L,Shestova O,Wang H,Li YM,Bhandoola A,Aster JC,Blacklow SC,Pear WS
16-0193 was used in Flow cytometry/Cell sorting to show that dimeric Notch transcriptional complexes are required for T-cell maturation and leukemic transformation but are dispensable for T-cell fate specification from a multipotential precursor.
Mon Nov 01 00:00:00 EDT 2010
The PI3K isoforms p110alpha and p110delta are essential for pre-B cell receptor signaling and B cell development.
Science signaling
Ramadani F,Bolland DJ,Garcon F,Emery JL,Vanhaesebroeck B,Corcoran AE,Okkenhaug K
16-0193 was used in Flow cytometry/Cell sorting to study how either p110alpha or p110delta can mediate tonic signaling from the BCR, but only p110delta can contribute to antigen-dependent activation of B cells.
Tue Aug 10 00:00:00 EDT 2010
Cutting edge: adaptive versus innate receptor signals selectively control the pool sizes of murine IFN-γ- or IL-17-producing γδ T cells upon infection.
Journal of immunology (Baltimore, Md. : 1950)
Ribot JC,Chaves-Ferreira M,d'Orey F,Wencker M,Gonçalves-Sousa N,Decalf J,Simas JP,Hayday AC,Silva-Santos B
16-0193 was used in Flow cytometry/Cell sorting to investigate the properties of γδ T lymphocytes for adaptive and innate immunity.
Wed Dec 01 00:00:00 EST 2010
B-cell homeostasis requires complementary CD22 and BLyS/BR3 survival signals.
International immunology
Smith SH,Haas KM,Poe JC,Yanaba K,Ward CD,Migone TS,Tedder TF
16-0193 was used in Flow cytometry/Cell sorting to support a model whereby B cells must integrate varied signals, including those from the BLyS- BR3 axis, CD22-ligand binding and antigen-receptor-mediated tonic signaling for their homeostatic maintenance in vivo.
Sun Aug 01 00:00:00 EDT 2010
AID constrains germinal center size by rendering B cells susceptible to apoptosis.
Blood
Zaheen A,Boulianne B,Parsa JY,Ramachandran S,Gommerman JL,Martin A
16-0193 was used in Flow cytometry/Cell sorting to report a link between AID-induced DNA damage and B-cell apoptosis that has implications for the development of B-cell disorders.
Thu Jul 16 00:00:00 EDT 2009
Systemic hypoxia enhances bactericidal activities of human polymorphonuclear leuocytes.
Clinical science (London, England : 1979)
Wang JS,Liu HC
16-0193 was used in Flow cytometry/Cell sorting to conclude that exposure to 12% O2 promotes the chemotactic, phagocytic and oxidative burst activities of polymorphonuclear leucocytes.
Fri May 01 00:00:00 EDT 2009
Chemokine-like receptor-1 expression by central nervous system-infiltrating leukocytes and involvement in a model of autoimmune demyelinating disease.
Journal of immunology (Baltimore, Md. : 1950)
Graham KL,Zabel BA,Loghavi S,Zuniga LA,Ho PP,Sobel RA,Butcher EC
16-0193 was used in Flow cytometry/Cell sorting to investigate the involvement of chemokine-like receptor-1 in experimental autoimmune encephalomyelitis.
Sun Nov 15 00:00:00 EST 2009
Id1 represses osteoclast-dependent transcription and affects bone formation and hematopoiesis.
PloS one
Chan AS,Jensen KK,Skokos D,Doty S,Lederman HK,Kaplan RN,Rafii S,Rivella S,Lyden D
16-0193 was used in Flow cytometry/Cell sorting to identify Id1 as crucial for the dynamic cross-talk between bone and bone marrow haematopoietic cells.
Tue Nov 24 00:00:00 EST 2009
Toll-like receptor 3 signaling on macrophages is required for survival following coxsackievirus B4 infection.
PloS one
Richer MJ,Lavallée DJ,Shanina I,Horwitz MS
16-0193 was used in Flow cytometry/Cell sorting to demonstrate that TLR3 is essential in recognizing the molecular signatures associated with specific viruses including CB4.
Tue Feb 03 00:00:00 EST 2009
The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues.
Nature immunology
Waskow C,Liu K,Darrasse-Jèze G,Guermonprez P,Ginhoux F,Merad M,Shengelia T,Yao K,Nussenzweig M
16-0193-81 was used in Immunohistochemistry to investigate the hematopoietic growth factors regulating dendritic development.
Sun Jun 01 00:00:00 EDT 2008
The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues.
Nature immunology
Waskow C,Liu K,Darrasse-Jèze G,Guermonprez P,Ginhoux F,Merad M,Shengelia T,Yao K,Nussenzweig M
16-0193-81 was used in Immunohistochemistry to investigate the hematopoietic growth factors regulating dendritic development.
Sun Jun 01 00:00:00 EDT 2008
Adaptive immune neuroprotection in G93A-SOD1 amyotrophic lateral sclerosis mice.
PloS one
Banerjee R,Mosley RL,Reynolds AD,Dhar A,Jackson-Lewis V,Gordon PH,Przedborski S,Gendelman HE
16-0193 was used in Immunohistochemistry on frozen tissues to investigate the role of T cell immunity in human G93A SOD1 Tg mice and in ALS patients.
Wed Jul 23 00:00:00 EDT 2008
