Search Thermo Fisher Scientific
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This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Mouse TACI/TNFRSF13B(CD267).
Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 and April/TALL-2, respectively. BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. April regulates immunological and non-immunological cell growth. Three receptors, BCMA, TACI, and BAFF-R, for BAFF and April were recently identified. TACI, like BCMA, binds BAFF and April. TACI and its ligands regulate humoral immune responses, activate NF-kappa-B and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD267; transmembrane activator and calcium-modulating and cyclophilin ligand interactor; Transmembrane activator and CAML interactor; Tumor necrosis factor receptor superfamily member 13B
Gene Aliases: 1200009E08Rik; Taci; Tnfrsf13b
UniProt ID: (Mouse) Q9ET35
Entrez Gene ID: (Mouse) 57916
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