Product References
Perinatal murine cytomegalovirus infection reshapes the transcriptional profile and functionality of NK cells.
Nature communications
Rožmanić C,Lisnić B,Pribanić Matešić M,Mihalić A,Hiršl L,Park E,Lesac Brizić A,Indenbirken D,Viduka I,Šantić M,Adler B,Yokoyama WM,Krmpotić A,Juranić Lisnić V,Jonjić S,Brizić I
Published figure using CD27 monoclonal antibody (Product # 17-0271-82) in Flow Cytometry
Thu Oct 12 00:00:00 EDT 2023
The transcription factor Bach2 negatively regulates murine natural killer cell maturation and function.
eLife
Li S,Bern MD,Miao B,Fan C,Xing X,Inoue T,Piersma SJ,Wang T,Colonna M,Kurosaki T,Yokoyama WM
17-0271-82 was used in Flow cytometry/Cell sorting to investigate the role of Bach2 in natural killer (NK) cell development, revealing that Bach2 expression peaked in immature CD27+CD11b+ cells, and its deficiency led to increased proportions of terminally differentiated NK cells with enhanced granzyme and cytokine production, as well as improved NK cell-mediated control of tumor metastasis.
Mon Oct 03 00:00:00 EDT 2022
The transcription factor Bach2 negatively regulates murine natural killer cell maturation and function.
eLife
Li S,Bern MD,Miao B,Fan C,Xing X,Inoue T,Piersma SJ,Wang T,Colonna M,Kurosaki T,Yokoyama WM
17-0271-82 was used in Flow cytometry/Cell sorting to investigate the role of Bach2 in natural killer (NK) cell development, revealing that Bach2 expression peaked in immature CD27+CD11b+ cells, and its deficiency led to increased proportions of terminally differentiated NK cells with enhanced granzyme and cytokine production, as well as improved NK cell-mediated control of tumor metastasis.
Mon Oct 03 00:00:00 EDT 2022
The transcriptional repressor ID2 supports natural killer cell maturation by controlling TCF1 amplitude.
The Journal of experimental medicine
Li ZY,Morman RE,Hegermiller E,Sun M,Bartom ET,Maienschein-Cline M,Sigvardsson M,Kee BL
Published figure using CD27 monoclonal antibody (Product # 17-0271-82) in Flow Cytometry
Mon Jun 07 00:00:00 EDT 2021
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
Published figure using CD27 monoclonal antibody (Product # 17-0271-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory.
Cell reports
Cannons JL,Villarino AV,Kapnick SM,Preite S,Shih HY,Gomez-Rodriguez J,Kaul Z,Shibata H,Reilley JM,Huang B,Handon R,McBain IT,Gossa S,Wu T,Su HC,McGavern DB,O'Shea JJ,McGuire PJ,Uzel G,Schwartzberg PL
Published figure using CD27 monoclonal antibody (Product # 17-0271-82) in Flow Cytometry
Tue Oct 12 00:00:00 EDT 2021
Effect of Subcutaneous Anti-CD20 Antibody-Mediated B Cell Depletion on Susceptibility to Pneumocystis Infection in Mice.
mSphere
Dai G,Noell K,Weckbecker G,Kolls JK
Published figure using CD27 monoclonal antibody (Product # 17-0271-82) in Flow Cytometry
Wed May 05 00:00:00 EDT 2021
Immune cell phenotypes associated with disease severity and long-term neutralizing antibody titers after natural dengue virus infection.
Cell reports. Medicine
Rouers A,Chng MHY,Lee B,Rajapakse MP,Kaur K,Toh YX,Sathiakumar D,Loy T,Thein TL,Lim VWX,Singhal A,Yeo TW,Leo YS,Vora KA,Casimiro D,Lim B,Tucker-Kellogg L,Rivino L,Newell EW,Fink K
Published figure using CD27 monoclonal antibody (Product # 17-0271-82) in Flow Cytometry
Tue May 18 00:00:00 EDT 2021
Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies.
Cell reports
Seydoux E,Wan YH,Feng J,Wall A,Aljedani S,Homad LJ,MacCamy AJ,Weidle C,Gray MD,Brumage L,Taylor JJ,Pancera M,Stamatatos L,McGuire AT
Published figure using CD27 monoclonal antibody (Product # 17-0271-82) in Flow Cytometry
Tue May 04 00:00:00 EDT 2021
Ontogenic timing, T cell receptor signal strength, and Notch signaling direct γδ T cell functional differentiation in vivo.
Cell reports
Chen ELY,Lee CR,Thompson PK,Wiest DL,Anderson MK,Zúñiga-Pflücker JC
Published figure using CD27 monoclonal antibody (Product # 17-0271-82) in Flow Cytometry
Tue Jun 08 00:00:00 EDT 2021
Th2 Biased Immunity With Altered B Cell Profiles in Circulation of Patients With Sporotrichosis Caused by Sporothrix globosa.
Frontiers in immunology
Zu J,Yao L,Song Y,Cui Y,Guan M,Chen R,Zhen Y,Li S
Published figure using CD27 monoclonal antibody (Product # 17-0271-82) in Flow Cytometry
Mon May 31 00:00:00 EDT 2021
Control of Viral Infection by Natural Killer Cell Inhibitory Receptors.
Cell reports
Parikh BA,Bern MD,Piersma SJ,Yang L,Beckman DL,Poursine-Laurent J,Plougastel-Douglas B,Yokoyama WM
17-0271 was used in Flow cytometry/Cell sorting to show MHC-I-restricted control of murine cytomegalovirus (MCMV) infection in vivo that is NK cell dependent.
Tue Jul 28 00:00:00 EDT 2020
Iterative Single-Cell Analyses Define the Transcriptome of the First Functional Hematopoietic Stem Cells.
Cell reports
Vink CS,Calero-Nieto FJ,Wang X,Maglitto A,Mariani SA,Jawaid W,Göttgens B,Dzierzak E
Tue May 12 00:00:00 EDT 2020
Interleukin-15 Complex Treatment Protects Mice from Cerebral Malaria by Inducing Interleukin-10-Producing Natural Killer Cells.
Immunity
Burrack KS,Huggins MA,Taras E,Dougherty P,Henzler CM,Yang R,Alter S,Jeng EK,Wong HC,Felices M,Cichocki F,Miller JS,Hart GT,Johnson AJ,Jameson SC,Hamilton SE
17-0271-82 was used in Flow Cytometry to identify a regulatory role for cytokine-stimulated NK cells in the prevention of a pathogenic immune response.
Tue Apr 17 00:00:00 EDT 2018
BALDR: a computational pipeline for paired heavy and light chain immunoglobulin reconstruction in single-cell RNA-seq data.
Genome medicine
Upadhyay AA,Kauffman RC,Wolabaugh AN,Cho A,Patel NB,Reiss SM,Havenar-Daughton C,Dawoud RA,Tharp GK,Sanz I,Pulendran B,Crotty S,Lee FE,Wrammert J,Bosinger SE
Published figure using CD27 monoclonal antibody (Product # 17-0271-82) in Flow Cytometry
Tue Mar 20 00:00:00 EDT 2018
Crosstalks between mTORC1 and mTORC2 variagate cytokine signaling to control NK maturation and effector function.
Nature communications
Wang F,Meng M,Mo B,Yang Y,Ji Y,Huang P,Lai W,Pan X,You T,Luo H,Guan X,Deng Y,Yuan S,Chu J,Namaka M,Hughes T,Ye L,Yu J,Li X,Deng Y
Published figure using CD27 monoclonal antibody (Product # 17-0271-82) in Flow Cytometry
Mon Nov 19 00:00:00 EST 2018
Identification of Nascent Memory CD8 T Cells and Modeling of Their Ontogeny.
Cell systems
Crauste F,Mafille J,Boucinha L,Djebali S,Gandrillon O,Marvel J,Arpin C
17-0271-82 was used in Flow Cytometry to identify Bcl2 and Mki67 as a marker combination that enables the tracking of nascent memory cells within the effector phase.
Wed Mar 22 00:00:00 EDT 2017
Broadening CD4+ and CD8+ T Cell Responses against Hepatitis C Virus by Vaccination with NS3 Overlapping Peptide Panels in Cross-Priming Liposomes.
Journal of virology
Filskov J,Mikkelsen M,Hansen PR,Christensen JP,Thomsen AR,Andersen P,Bukh J,Agger EM
17-0271 was used in Flow cytometry/Cell sorting to develop a novel peptide-based nanoparticle vaccine strategy aimed at generating T cell immunity against potential subdominant T cell epitopes that are not efficiently targeted by vaccination with full-length recombinant protein or infection with Hepatitis C virus.
Sat Jul 15 00:00:00 EDT 2017
The breast tumor microenvironment alters the phenotype and function of natural killer cells.
Cellular & molecular immunology
Krneta T,Gillgrass A,Chew M,Ashkar AA
Published figure using CD27 monoclonal antibody (Product # 17-0271-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNFAIP3/A20.
The Journal of experimental medicine
Drennan MB,Govindarajan S,Verheugen E,Coquet JM,Staal J,McGuire C,Taghon T,Leclercq G,Beyaert R,van Loo G,Lambrecht BN,Elewaut D
17-0271 was used in Flow cytometry/Cell sorting to show that negative regulation of TCR signalling during NKT development controls the differentiation and survival of NKT1 and NKT2 cells.
Mon Sep 19 00:00:00 EDT 2016
NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation.
Nature communications
Yang M,Chen S,Du J,He J,Wang Y,Li Z,Liu G,Peng W,Zeng X,Li D,Xu P,Guo W,Chang Z,Wang S,Tian Z,Dong Z
Published figure using CD27 monoclonal antibody (Product # 17-0271-82) in Flow Cytometry
Wed Sep 07 00:00:00 EDT 2016
Production of IL-10 by CD4(+) regulatory T cells during the resolution of infection promotes the maturation of memory CD8(+) T cells.
Nature immunology
Laidlaw BJ,Cui W,Amezquita RA,Gray SM,Guan T,Lu Y,Kobayashi Y,Flavell RA,Kleinstein SH,Craft J,Kaech SM
Published figure using CD27 monoclonal antibody (Product # 17-0271-82) in Flow Cytometry
Sat Aug 01 00:00:00 EDT 2015
IL-1β-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKβ.
Nature immunology
Hsu LC,Enzler T,Seita J,Timmer AM,Lee CY,Lai TY,Yu GY,Lai LC,Temkin V,Sinzig U,Aung T,Nizet V,Weissman IL,Karin M
17-0271 was used in Flow cytometry/Cell sorting to observe neutrophilia in mice with an inducible deletion of IKKβ (Ikkβ(δ) mice) which is believed to be critical for innate immunity.
Tue Feb 01 00:00:00 EST 2011
Plasmid vector-linked maturation of natural killer (NK) cells is coupled to antigen-dependent NK cell activation during DNA-based immunization in mice.
Journal of virology
Zhu R,Mancini-Bourgine M,Zhang XM,Bayard F,Deng Q,Michel ML
17-0271 was used in Flow cytometry/Cell sorting to analyze the mechanisms underlying NK cell activation, and their potential role in adaptive immunity during DNA-based immunization in mice.
Sat Oct 01 00:00:00 EDT 2011
Efficient generation of mucosal and systemic antigen-specific CD8+ T-cell responses following pulmonary DNA immunization.
Journal of virology
Bivas-Benita M,Bar L,Gillard GO,Kaufman DR,Simmons NL,Hovav AH,Letvin NL
17-0271 was used in Flow cytometry/Cell sorting to evaluate the ability of plasmid DNA to induce antigen-specific immune cell responses after pulmonary administration.
Tue Jun 01 00:00:00 EDT 2010
Niche recycling through division-independent egress of hematopoietic stem cells.
The Journal of experimental medicine
Bhattacharya D,Czechowicz A,Ooi AG,Rossi DJ,Bryder D,Weissman IL
17-0271 was used in Flow cytometry/Cell sorting to provide insight as to how HSC replacement can occur despite the residence of endogenous HSCs in niches.
Mon Nov 23 00:00:00 EST 2009
Reevaluating the CD8 T-cell response to herpes simplex virus type 1: involvement of CD8 T cells reactive to subdominant epitopes.
Journal of virology
Sheridan BS,Cherpes TL,Urban J,Kalinski P,Hendricks RL
17-0271 was used in Flow cytometry/Cell sorting to explore the properties of glycoprotein B-nonspecific trigeminal ganglia-resident CD8 T-cells and their role in maintaining viral latency.
Sun Mar 01 00:00:00 EST 2009
DNAM-1 promotes activation of cytotoxic lymphocytes by nonprofessional antigen-presenting cells and tumors.
The Journal of experimental medicine
Gilfillan S,Chan CJ,Cella M,Haynes NM,Rapaport AS,Boles KS,Andrews DM,Smyth MJ,Colonna M
17-0271 was used in Flow cytometry/Cell sorting to study the promoted activation of cytotoxic lymphocytes by nonprofessional antigen-presenting cells and tumors by dnam-1.
Mon Dec 22 00:00:00 EST 2008
Rapid memory CD8+ T-lymphocyte induction through priming with recombinant Mycobacterium smegmatis.
Journal of virology
Hovav AH,Cayabyab MJ,Panas MW,Santra S,Greenland J,Geiben R,Haynes BF,Jacobs WR,Letvin NL
17-0271 was used in Flow cytometry/Cell sorting to investigate novel priming immunogens that might be used in heterologous immunization regimens, showing that priming with Mycobacterium smegmatis leads to rapid memory CD8+ T-lymphocyte induction.
Mon Jan 01 00:00:00 EST 2007
Delayed, asynchronous, and reversible T-lineage specification induced by Notch/Delta signaling.
Genes & development
Taghon TN,David ES,Zúñiga-Pflücker JC,Rothenberg EV
17-0271 was used in Flow cytometry/Cell sorting to study how Notch/Delta signaling is not sufficient for T-lineage specification and commitment, but can be permissive for the maintenance and proliferation of uncommitted progenitors.
Fri Apr 15 00:00:00 EDT 2005
Identification of mast cell progenitors in adult mice.
Proceedings of the National Academy of Sciences of the United States of America
Chen CC,Grimbaldeston MA,Tsai M,Weissman IL,Galli SJ
17-0271 was used in Flow cytometry/Cell sorting to identify mast cell progenitors in mice and investigate their timeline of commitment to the mast cell lineage.
Tue Aug 09 00:00:00 EDT 2005