Product References
IGF2 Peptide-Based LYTACs for Targeted Degradation of Extracellular and Transmembrane Proteins.
Molecules (Basel, Switzerland)
Mikitiuk M,Barczyński J,Bielski P,Arciniega M,Tyrcha U,Hec A,Lipińska AD,Rychłowski M,Holak TA,Sitar T
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Fri Nov 10 00:00:00 UTC 2023
CRISPR screening identifies the deubiquitylase ATXN3 as a PD-L1-positive regulator for tumor immune evasion.
The Journal of clinical investigation
Wang S,Iyer R,Han X,Wei J,Li N,Cheng Y,Zhou Y,Gao Q,Zhang L,Yan M,Sun Z,Fang D
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Fri Dec 01 00:00:00 UTC 2023
The Cell-Autonomous Pro-Metastatic Activities of PD-L1 in Breast Cancer Are Regulated by N-Linked Glycosylation-Dependent Activation of STAT3 and STAT1.
Cells
Erlichman N,Meshel T,Baram T,Abu Raiya A,Horvitz T,Ben-Yaakov H,Ben-Baruch A
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Sat Sep 23 00:00:00 UTC 2023
Engineered Human Dendritic Cell Exosomes as Effective Delivery System for Immune Modulation.
International journal of molecular sciences
Elsayed R,Elashiry M,Tran C,Yang T,Carroll A,Liu Y,Hamrick M,Cutler CW
46-5983-42 was used in Flow cytometry/Cell sorting to report in a mouse model of periodontitis that custom murine DC-derived exo subtypes could reprogram the immune response toward a bone-sparing or bone-loss phenotype, depending on immune profile.
Tue Jul 11 00:00:00 UTC 2023
Engineered Human Dendritic Cell Exosomes as Effective Delivery System for Immune Modulation.
International journal of molecular sciences
Elsayed R,Elashiry M,Tran C,Yang T,Carroll A,Liu Y,Hamrick M,Cutler CW
46-5983-42 was used in Flow cytometry/Cell sorting to report in a mouse model of periodontitis that custom murine DC-derived exo subtypes could reprogram the immune response toward a bone-sparing or bone-loss phenotype, depending on immune profile.
Tue Jul 11 00:00:00 UTC 2023
NKp44-Derived Peptide Used in Combination Stimulates Antineoplastic Efficacy of Targeted Therapeutic Drugs.
International journal of molecular sciences
Iraqi M,Bolel P,Sarkar R,Bhattacharya B,Abu Ahmad M,Edri A,Roisman LC,Elkabets M,Shalata W,Peled N,Porgador A
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Mon Nov 14 00:00:00 UTC 2022
GM-CSF, Flt3-L and IL-4 affect viability and function of conventional dendritic cell types 1 and 2.
Frontiers in immunology
Lellahi SM,Azeem W,Hua Y,Gabriel B,Paulsen Rye K,Reikvam H,Kalland KH
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Wed Feb 01 00:00:00 UTC 2023
PD-L1 CAR effector cells induce self-amplifying cytotoxic effects against target cells.
Journal for immunotherapy of cancer
Bajor M,Graczyk-Jarzynka A,Marhelava K,Burdzinska A,Muchowicz A,Goral A,Zhylko A,Soroczynska K,Retecki K,Krawczyk M,Klopotowska M,Pilch Z,Paczek L,Malmberg KJ,Wälchli S,Winiarska M,Zagozdzon R
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Sat Jan 01 00:00:00 UTC 2022
GM-CSF-activated human dendritic cells promote type 1 T follicular helper cell polarization in a CD40-dependent manner.
Journal of cell science
Korniotis S,Saichi M,Trichot C,Hoffmann C,Amblard E,Viguier A,Grondin S,Noel F,Mattoo H,Soumelis V
46-5983-42 was used in Flow cytometry/Cell sorting to report that human blood CD1c+ dendritic cells activated by GM-CSF (also known as CSF2) drive the differentiation of naive CD4+ T cells into Tfh1 cells.
Tue Nov 01 00:00:00 UTC 2022
Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression.
Nature communications
Qi M,Xia Y,Wu Y,Zhang Z,Wang X,Lu L,Dai C,Song Y,Xu K,Ji W,Zhan L
46-5983-42 was used in Flow Cytometry to demonstrate that Lin28B promotes lung metastasis of breast cancer by building an immune-suppressive pre-metastatic niche.
Wed Feb 16 00:00:00 UTC 2022
Ruxolitinib reverses checkpoint inhibition by reducing programmed cell death ligand-1 (PD-L1) expression and increases anti-tumour effects of T cells in multiple myeloma.
British journal of haematology
Chen H,Li M,Ng N,Yu E,Bujarski S,Yin Z,Wen M,Hekmati T,Field D,Wang J,Nassir I,Yu J,Huang J,Daniely D,Wang CS,Xu N,Spektor TM,Berenson JR
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Mon Feb 01 00:00:00 UTC 2021
Different Induction of PD-L1 (CD274) and PD-1 (CD279) Expression in THP-1-Differentiated Types 1 and 2 Macrophages.
Journal of inflammation research
Lai CY,Tseng PC,Chen CL,Satria RD,Wang YT,Lin CF
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Wed Apr 27 00:00:00 UTC 2022
Protecting Stem Cell Derived Pancreatic Beta-Like Cells From Diabetogenic T Cell Recognition.
Frontiers in endocrinology
Castro-Gutierrez R,Alkanani A,Mathews CE,Michels A,Russ HA
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Thu Feb 10 00:00:00 UTC 2022
IL-27 Mediates PD-L1 Expression and Release by Human Mesothelioma Cells.
Cancers
Carbotti G,Dozin B,Martini S,Giordano C,Scordamaglia F,Croce M,Filaci G,Ferrini S,Fabbi M
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Mon Aug 09 00:00:00 UTC 2021
Protocol for high-throughput compound screening using flow cytometry in THP-1 cells.
STAR protocols
Spangenberg SH,Zavareh RB,Lairson LL
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Fri Jun 18 00:00:00 UTC 2021
Increased Incidence of Venous Thromboembolism with Cancer Immunotherapy.
Med (New York, N.Y.)
Roopkumar J,Swaidani S,Kim AS,Thapa B,Gervaso L,Hobbs BP,Wei W,Alban TJ,Funchain P,Kundu S,Sangwan N,Rayman P,Pavicic PG,Diaz-Montero CM,Barnard J,McCrae KR,Khorana AA
46-5983-42 was used in ChIP assay to investigate if venous thromboembolism is an underappreciated and important immune-related adverse event associated with cancer immunotherapy.
Fri Apr 09 00:00:00 UTC 2021
X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19.
Science immunology
Asano T,Boisson B,Onodi F,Matuozzo D,Moncada-Velez M,Maglorius Renkilaraj MRL,Zhang P,Meertens L,Bolze A,Materna M,Korniotis S,Gervais A,Talouarn E,Bigio B,Seeleuthner Y,Bilguvar K,Zhang Y,Neehus AL,Ogishi M,Pelham SJ,Le Voyer T,Rosain J,Philippot Q,Soler-Palacín P,Colobran R,Martin-Nalda A,Rivière JG,Tandjaoui-Lambiotte Y,Chaïbi K,Shahrooei M,Darazam IA,Olyaei NA,Mansouri D,Hatipoğlu N,Palabiyik F,Ozcelik T,Novelli G,Novelli A,Casari G,Aiuti A,Carrera P,Bondesan S,Barzaghi F,Rovere-Querini P,Tresoldi C,Franco JL,Rojas J,Reyes LF,Bustos IG,Arias AA,Morelle G,Christèle K,Troya J,Planas-Serra L,Schlüter A,Gut M,Pujol A,Allende LM,Rodriguez-Gallego C,Flores C,Cabrera-Marante O,Pleguezuelo DE,de Diego RP,Keles S,Aytekin G,Akcan OM,Bryceson YT,Bergman P,Brodin P,Smole D,Smith CIE,Norlin AC,Campbell TM,Covill LE,Hammarström L,Pan-Hammarström Q,Abolhassani H,Mane S,Marr N,Ata M,Al Ali F,Khan T,Spaan AN,Dalgard CL,Bonfanti P,Biondi A,Tubiana S,Burdet C,Nussbaum R,Kahn-Kirby A,Snow AL,Bustamante J,Puel A,Boisson-Dupuis S,Zhang SY,Béziat V,Lifton RP,Bastard P,Notarangelo LD,Abel L,Su HC,Jouanguy E,Amara A,Soumelis V,Cobat A,Zhang Q,Casanova JL
46-5983-42 was used in Flow Cytometry to report very rare, biochemically deleterious X-linked TLR7 variants in 16 unrelated male individuals with unexplained critical COVID-19 pneumonia.
Thu Aug 19 00:00:00 UTC 2021
X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19.
Science immunology
Asano T,Boisson B,Onodi F,Matuozzo D,Moncada-Velez M,Maglorius Renkilaraj MRL,Zhang P,Meertens L,Bolze A,Materna M,Korniotis S,Gervais A,Talouarn E,Bigio B,Seeleuthner Y,Bilguvar K,Zhang Y,Neehus AL,Ogishi M,Pelham SJ,Le Voyer T,Rosain J,Philippot Q,Soler-Palacín P,Colobran R,Martin-Nalda A,Rivière JG,Tandjaoui-Lambiotte Y,Chaïbi K,Shahrooei M,Darazam IA,Olyaei NA,Mansouri D,Hatipoğlu N,Palabiyik F,Ozcelik T,Novelli G,Novelli A,Casari G,Aiuti A,Carrera P,Bondesan S,Barzaghi F,Rovere-Querini P,Tresoldi C,Franco JL,Rojas J,Reyes LF,Bustos IG,Arias AA,Morelle G,Christèle K,Troya J,Planas-Serra L,Schlüter A,Gut M,Pujol A,Allende LM,Rodriguez-Gallego C,Flores C,Cabrera-Marante O,Pleguezuelo DE,de Diego RP,Keles S,Aytekin G,Akcan OM,Bryceson YT,Bergman P,Brodin P,Smole D,Smith CIE,Norlin AC,Campbell TM,Covill LE,Hammarström L,Pan-Hammarström Q,Abolhassani H,Mane S,Marr N,Ata M,Al Ali F,Khan T,Spaan AN,Dalgard CL,Bonfanti P,Biondi A,Tubiana S,Burdet C,Nussbaum R,Kahn-Kirby A,Snow AL,Bustamante J,Puel A,Boisson-Dupuis S,Zhang SY,Béziat V,Lifton RP,Bastard P,Notarangelo LD,Abel L,Su HC,Jouanguy E,Amara A,Soumelis V,Cobat A,Zhang Q,Casanova JL
46-5983-42 was used in Flow Cytometry to report very rare, biochemically deleterious X-linked TLR7 variants in 16 unrelated male individuals with unexplained critical COVID-19 pneumonia.
Thu Aug 19 00:00:00 UTC 2021
Evaluation of β-Catenin Inhibition of Axitinib and Nitazoxanide in Human Monocyte-Derived Dendritic Cells.
Biomedicines
Azeem W,Bakke RM,Gabriel B,Appel S,Øyan AM,Kalland KH
46-5983-42 was used in Flow Cytometry to study the effects axitinib and nitazoxanide on β-Catenin Inhibition in Human Monocyte-Derived Dendritic Cells.
Tue Aug 03 00:00:00 UTC 2021
TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9.
Nature
Heinz LX,Lee J,Kapoor U,Kartnig F,Sedlyarov V,Papakostas K,César-Razquin A,Essletzbichler P,Goldmann U,Stefanovic A,Bigenzahn JW,Scorzoni S,Pizzagalli MD,Bensimon A,Müller AC,King FJ,Li J,Girardi E,Mbow ML,Whitehurst CE,Rebsamen M,Superti-Furga G
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Fri May 01 00:00:00 UTC 2020
β-Catenin induces transcriptional expression of PD-L1 to promote glioblastoma immune evasion.
The Journal of experimental medicine
Du L,Lee JH,Jiang H,Wang C,Wang S,Zheng Z,Shao F,Xu D,Xia Y,Li J,Zheng Y,Qian X,Li X,Kim HR,Xing D,Liu P,Lu Z,Lyu J
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Mon Nov 02 00:00:00 UTC 2020
Protein kinase D3 regulates the expression of the immunosuppressive protein, PD‑L1, through STAT1/STAT3 signaling.
International journal of oncology
Cui B,Chen J,Luo M,Wang L,Chen H,Kang Y,Wang J,Zhou X,Feng Y,Zhang P
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Wed Apr 01 00:00:00 UTC 2020
Contribution of GATA6 to homeostasis of the human upper pilosebaceous unit and acne pathogenesis.
Nature communications
Oulès B,Philippeos C,Segal J,Tihy M,Vietri Rudan M,Cujba AM,Grange PA,Quist S,Natsuga K,Deschamps L,Dupin N,Donati G,Watt FM
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Tue Oct 20 00:00:00 UTC 2020
Cancer cell-intrinsic expression of MHC II in lung cancer cell lines is actively restricted by MEK/ERK signaling and epigenetic mechanisms.
Journal for immunotherapy of cancer
Neuwelt AJ,Kimball AK,Johnson AM,Arnold BW,Bullock BL,Kaspar RE,Kleczko EK,Kwak JW,Wu MH,Heasley LE,Doebele RC,Li HY,Nemenoff RA,Clambey ET
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Wed Apr 01 00:00:00 UTC 2020
Dual Pro- and Anti-Inflammatory Features of Monocyte-Derived Dendritic Cells.
Frontiers in immunology
Azeem W,Bakke RM,Appel S,Øyan AM,Kalland KH
46-5983 was used in Flow cytometry/Cell sorting to investigate the hypothesis that aberrant differentiation or induction of dual pro- and anti-inflammatory features may be β-catenin dependent in monocyte-derived dendritic cells (moDCs).
Fri Mar 19 00:00:00 UTC 2021
A Quantitative Multivariate Model of Human Dendritic Cell-T Helper Cell Communication.
Cell
Grandclaudon M,Perrot-Dockès M,Trichot C,Karpf L,Abouzid O,Chauvin C,Sirven P,Abou-Jaoudé W,Berger F,Hupé P,Thieffry D,Sansonnet L,Chiquet J,Lévy-Leduc C,Soumelis V
46-5983 was used in Flow cytometry/Cell sorting to provide a unique resource to decipher the complex combinatorial rules governing DC-Th cell communication and guide their manipulation for vaccine design and immunotherapies.
Thu Oct 03 00:00:00 UTC 2019
PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways.
Immunity
Zhao Y,Lee CK,Lin CH,Gassen RB,Xu X,Huang Z,Xiao C,Bonorino C,Lu LF,Bui JD,Hui E
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Tue Dec 17 00:00:00 UTC 2019
Phospho‑STAT1 expression as a potential biomarker for anti‑PD‑1/anti‑PD‑L1 immunotherapy for breast cancer.
International journal of oncology
Nakayama Y,Mimura K,Tamaki T,Shiraishi K,Kua LF,Koh V,Ohmori M,Kimura A,Inoue S,Okayama H,Suzuki Y,Nakazawa T,Ichikawa D,Kono K
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Sat Jun 01 00:00:00 UTC 2019
Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy.
Cell reports
Celis-Gutierrez J,Blattmann P,Zhai Y,Jarmuzynski N,Ruminski K,Grégoire C,Ounoughene Y,Fiore F,Aebersold R,Roncagalli R,Gstaiger M,Malissen B
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Tue Jun 11 00:00:00 UTC 2019
High PD-L1 Expression Predicts for Worse Outcome of Leukemia Patients with Concomitant NPM1 and FLT3 Mutations.
International journal of molecular sciences
Brodská B,Otevřelová P,Šálek C,Fuchs O,Gašová Z,Kuželová K
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Mon Jun 10 00:00:00 UTC 2019
CA-170 - A Potent Small-Molecule PD-L1 Inhibitor or Not?
Molecules (Basel, Switzerland)
Musielak B,Kocik J,Skalniak L,Magiera-Mularz K,Sala D,Czub M,Stec M,Siedlar M,Holak TA,Plewka J
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Thu Aug 01 00:00:00 UTC 2019
TLR9 Mediated Tumor-Stroma Interactions in Human Papilloma Virus (HPV)-Positive Head and Neck Squamous Cell Carcinoma Up-Regulate PD-L1 and PD-L2.
Frontiers in immunology
Baruah P,Bullenkamp J,Wilson POG,Lee M,Kaski JC,Dumitriu IE
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Wed Oct 14 00:00:00 UTC 2020
Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids.
Cell
Dijkstra KK,Cattaneo CM,Weeber F,Chalabi M,van de Haar J,Fanchi LF,Slagter M,van der Velden DL,Kaing S,Kelderman S,van Rooij N,van Leerdam ME,Depla A,Smit EF,Hartemink KJ,de Groot R,Wolkers MC,Sachs N,Snaebjornsson P,Monkhorst K,Haanen J,Clevers H,Schumacher TN,Voest EE
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Thu Sep 06 00:00:00 UTC 2018
Dominant Role for Regulatory T Cells in Protecting Females Against Pulmonary Hypertension.
Circulation research
Tamosiuniene R,Manouvakhova O,Mesange P,Saito T,Qian J,Sanyal M,Lin YC,Nguyen LP,Luria A,Tu AB,Sante JM,Rabinovitch M,Fitzgerald DJ,Graham BB,Habtezion A,Voelkel NF,Aurelian L,Nicolls MR
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Fri Jun 08 00:00:00 UTC 2018
Specific expression of PD-L1 in RELA-fusion supratentorial ependymoma: Implications for PD-1-targeted therapy.
Pediatric blood & cancer
Witt DA,Donson AM,Amani V,Moreira DC,Sanford B,Hoffman LM,Handler MH,Levy JMM,Jones KL,Nellan A,Foreman NK,Griesinger AM
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Tue May 01 00:00:00 UTC 2018
Disruption of PD-1 Enhanced the Anti-tumor Activity of Chimeric Antigen Receptor T Cells Against Hepatocellular Carcinoma.
Frontiers in pharmacology
Guo X,Jiang H,Shi B,Zhou M,Zhang H,Shi Z,Du G,Luo H,Wu X,Wang Y,Sun R,Li Z
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Thu Sep 28 00:00:00 UTC 2023
Oncofetal gene SALL4 reactivation by hepatitis B virus counteracts miR-200c in PD-L1-induced T cell exhaustion.
Nature communications
Sun C,Lan P,Han Q,Huang M,Zhang Z,Xu G,Song J,Wang J,Wei H,Zhang J,Sun R,Zhang C,Tian Z
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Wed Mar 28 00:00:00 UTC 2018
Similarities and differences between helminth parasites and cancer cell lines in shaping human monocytes: Insights into parallel mechanisms of immune evasion.
PLoS neglected tropical diseases
Narasimhan PB,Akabas L,Tariq S,Huda N,Bennuru S,Sabzevari H,Hofmeister R,Nutman TB,Tolouei Semnani R
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Sun Apr 01 00:00:00 UTC 2018
PD-L1 expression in medulloblastoma: an evaluation by subgroup.
Oncotarget
Martin AM,Nirschl CJ,Polanczyk MJ,Bell WR,Nirschl TR,Harris-Bookman S,Phallen J,Hicks J,Martinez D,Ogurtsova A,Xu H,Sullivan LM,Meeker AK,Raabe EH,Cohen KJ,Eberhart CG,Burger PC,Santi M,Taube JM,Pardoll DM,Drake CG,Lim M
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Tue Apr 10 00:00:00 UTC 2018
PD-1 axis expression in musculoskeletal tumors and antitumor effect of nivolumab in osteosarcoma model of humanized mouse.
Journal of hematology & oncology
Zheng B,Ren T,Huang Y,Sun K,Wang S,Bao X,Liu K,Guo W
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Tue Feb 06 00:00:00 UTC 2018
Apigenin suppresses PD-L1 expression in melanoma and host dendritic cells to elicit synergistic therapeutic effects.
Journal of experimental & clinical cancer research : CR
Xu L,Zhang Y,Tian K,Chen X,Zhang R,Mu X,Wu Y,Wang D,Wang S,Liu F,Wang T,Zhang J,Liu S,Zhang Y,Tu C,Liu H
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Mon Oct 29 00:00:00 UTC 2018
Antigen-Presenting Cell-Intrinsic PD-1 Neutralizes PD-L1 in cis to Attenuate PD-1 Signaling in T Cells.
Cell reports
Zhao Y,Harrison DL,Song Y,Ji J,Huang J,Hui E
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Tue Jul 10 00:00:00 UTC 2018
Interferon-gamma drives programmed death-ligand 1 expression on islet β cells to limit T cell function during autoimmune diabetes.
Scientific reports
Osum KC,Burrack AL,Martinov T,Sahli NL,Mitchell JS,Tucker CG,Pauken KE,Papas K,Appakalai B,Spanier JA,Fife BT
46-5983 was used in Flow cytometry/Cell sorting to suggest that insulin-producing Β cells respond to pancreatic inflammation and IFN-γ production by upregulating PD-L1 expression to limit self-reactive T cells.
Tue May 29 00:00:00 UTC 2018
Oncogenic RAS Signaling Promotes Tumor Immunoresistance by Stabilizing PD-L1 mRNA.
Immunity
Coelho MA,de Carné Trécesson S,Rana S,Zecchin D,Moore C,Molina-Arcas M,East P,Spencer-Dene B,Nye E,Barnouin K,Snijders AP,Lai WS,Blackshear PJ,Downward J
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Tue Dec 19 00:00:00 UTC 2017
Dichotomous Expression of TNF Superfamily Ligands on Antigen-Presenting Cells Controls Post-priming Anti-viral CD4+ T Cell Immunity.
Immunity
Chang YH,Wang KC,Chu KL,Clouthier DL,Tran AT,Torres Perez MS,Zhou AC,Abdul-Sater AA,Watts TH
46-5983-42 was used in Flow cytometry/Cell sorting to investigate how different subtypes of T cell antigen-presenting cell contribute to determining viral set point and disease outcome.
Tue Nov 21 00:00:00 UTC 2017
Retroviral Replicating Vector Delivery of miR-PDL1 Inhibits Immune Checkpoint PDL1 and Enhances Immune Responses In Vitro.
Molecular therapy. Nucleic acids
Lin AH,Twitty CG,Burnett R,Hofacre A,Mitchell LA,Espinoza FL,Gruber HE,Jolly DJ
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Fri Mar 17 00:00:00 UTC 2017
Mesenchymal Stromal Cell Secretion of Programmed Death-1 Ligands Regulates T Cell Mediated Immunosuppression.
Stem cells (Dayton, Ohio)
Davies LC,Heldring N,Kadri N,Le Blanc K
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Wed Mar 01 00:00:00 UTC 2017
Amplification of N-Myc is associated with a T-cell-poor microenvironment in metastatic neuroblastoma restraining interferon pathway activity and chemokine expression.
Oncoimmunology
Layer JP,Kronmüller MT,Quast T,van den Boorn-Konijnenberg D,Effern M,Hinze D,Althoff K,Schramm A,Westermann F,Peifer M,Hartmann G,Tüting T,Kolanus W,Fischer M,Schulte J,Hölzel M
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Tue Jan 12 00:00:00 UTC 2021
PD-L1/PD-1 expression and tumor-infiltrating lymphocytes in conjunctival melanoma.
Oncotarget
Cao J,Brouwer NJ,Richards KE,Marinkovic M,van Duinen S,Hurkmans D,Verdegaal EME,Jordanova ES,Jager MJ
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Tue Aug 15 00:00:00 UTC 2017
CD28 family of receptors on T cells in chronic HBV infection: Expression characteristics, clinical significance and correlations with PD-1 blockade.
Molecular medicine reports
Tang ZS,Hao YH,Zhang EJ,Xu CL,Zhou Y,Zheng X,Yang DL
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Mon Aug 01 00:00:00 UTC 2016
Expression of programmed death 1 ligand 1 on periodontal tissue cells as a possible protective feedback mechanism against periodontal tissue destruction.
Molecular medicine reports
Zhang J,Wang CM,Zhang P,Wang X,Chen J,Yang J,Lu W,Zhou W,Yuan W,Feng Y
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Tue Mar 01 00:00:00 UTC 2016
Paucity of PD-L1 expression in prostate cancer: innate and adaptive immune resistance.
Prostate cancer and prostatic diseases
Martin AM,Nirschl TR,Nirschl CJ,Francica BJ,Kochel CM,van Bokhoven A,Meeker AK,Lucia MS,Anders RA,DeMarzo AM,Drake CG
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Tue Dec 01 00:00:00 UTC 2015
Interleukin-25 Mediates Transcriptional Control of PD-L1 via STAT3 in Multipotent Human Mesenchymal Stromal Cells (hMSCs) to Suppress Th17 Responses.
Stem cell reports
Wang WB,Yen ML,Liu KJ,Hsu PJ,Lin MH,Chen PM,Sudhir PR,Chen CH,Chen CH,Sytwu HK,Yen BL
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Tue Sep 08 00:00:00 UTC 2015
IL-27 induces the expression of IDO and PD-L1 in human cancer cells.
Oncotarget
Carbotti G,Barisione G,Airoldi I,Mezzanzanica D,Bagnoli M,Ferrero S,Petretto A,Fabbi M,Ferrini S
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Tue Dec 22 00:00:00 UTC 2015
Alterations of immune response of Non-Small Cell Lung Cancer with Azacytidine.
Oncotarget
Wrangle J,Wang W,Koch A,Easwaran H,Mohammad HP,Vendetti F,Vancriekinge W,Demeyer T,Du Z,Parsana P,Rodgers K,Yen RW,Zahnow CA,Taube JM,Brahmer JR,Tykodi SS,Easton K,Carvajal RD,Jones PA,Laird PW,Weisenberger DJ,Tsai S,Juergens RA,Topalian SL,Rudin CM,Brock MV,Pardoll D,Baylin SB
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Fri Nov 01 00:00:00 UTC 2013
Ex vivo expanded hematopoietic stem cells overcome the MHC barrier in allogeneic transplantation.
Cell stem cell
Zheng J,Umikawa M,Zhang S,Huynh H,Silvany R,Chen BP,Chen L,Zhang CC
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Fri Aug 05 00:00:00 UTC 2011
Upregulation of programmed death-1 on T cells and programmed death ligand-1 on monocytes in septic shock patients.
Critical care (London, England)
Zhang Y,Li J,Lou J,Zhou Y,Bo L,Zhu J,Zhu K,Wan X,Cai Z,Deng X
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Wed Dec 07 00:00:00 UTC 2011
The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: a therapeutic target for CT-011, a novel monoclonal anti-PD-1 antibody.
Blood
Benson DM,Bakan CE,Mishra A,Hofmeister CC,Efebera Y,Becknell B,Baiocchi RA,Zhang J,Yu J,Smith MK,Greenfield CN,Porcu P,Devine SM,Rotem-Yehudar R,Lozanski G,Byrd JC,Caligiuri MA
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Thu Sep 30 00:00:00 UTC 2010
PD-1 is a regulator of NY-ESO-1-specific CD8+ T cell expansion in melanoma patients.
Journal of immunology (Baltimore, Md. : 1950)
Fourcade J,Kudela P,Sun Z,Shen H,Land SR,Lenzner D,Guillaume P,Luescher IF,Sander C,Ferrone S,Kirkwood JM,Zarour HM
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 46-5983-42) in Flow Cytometry
Fri May 01 00:00:00 UTC 2009
Expression of B7-H1 in inflammatory renal tubular epithelial cells.
Nephron. Experimental nephrology
Chen Y,Zhang J,Li J,Zou L,Zhao T,Tang Y,Wu Y
Fri Apr 21 00:00:00 UTC 2006
Expression of B7-H1 in inflammatory renal tubular epithelial cells.
Nephron. Experimental nephrology
Chen Y,Zhang J,Li J,Zou L,Zhao T,Tang Y,Wu Y
Fri Apr 21 00:00:00 UTC 2006
Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research
Ohigashi Y,Sho M,Yamada Y,Tsurui Y,Hamada K,Ikeda N,Mizuno T,Yoriki R,Kashizuka H,Yane K,Tsushima F,Otsuki N,Yagita H,Azuma M,Nakajima Y
Fri Apr 15 00:00:00 UTC 2005
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.jpg?time=20220826?time=20220826 "CD274 (PD-L1, B7-H1) Antibody (46-5983-42) in Flow")
.jpg?time=20220826?time=20220826 "CD274 (PD-L1, B7-H1) Antibody (46-5983-42) in Flow")
