Product References
Microbially-Induced Exosomes from Dendritic Cells Promote Paracrine Immune Senescence: Novel Mechanism of Bone Degenerative Disease in Mice.
Aging and disease
Elsayed R,Elashiry M,Liu Y,Morandini AC,El-Awady A,Elashiry MM,Hamrick M,Cutler CW
16-0032-82 was used in Flow cytometry/Cell sorting to conclude that immune senescence, compounded by advanced age, and accelerated by oral dysbiosis and its induced SASP exosomes, plays a pivotal role in the pathophysiology of experimental periodontitis.
Wed Feb 01 00:00:00 EST 2023
CISH impairs lysosomal function in activated T cells resulting in mitochondrial DNA release and inflammaging.
Nature aging
Jin J,Mu Y,Zhang H,Sturmlechner I,Wang C,Jadhav RR,Xia Q,Weyand CM,Goronzy JJ
16-0032-82 was used in Cell culture to show that activated T cells from older adults contribute to inflammation by releasing mitochondrial DNA (mtDNA) into their environment due to an increased expression of the cytokine-inducible SH2-containing protein (CISH).
Mon May 01 00:00:00 EDT 2023
The activity of the aryl hydrocarbon receptor in T cells tunes the gut microenvironment to sustain autoimmunity and neuroinflammation.
PLoS biology
Merchak AR,Cahill HJ,Brown LC,Brown RM,Rivet-Noor C,Beiter RM,Slogar ER,Olgun DG,Gaultier A
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Immunohistochemistry
Wed Feb 01 00:00:00 EST 2023
Targeting adrenergic receptors to mitigate invariant natural killer T cells-induced acute liver injury.
iScience
Gonzatti MB,Freire BM,Antunes MM,de Menezes GB,Talbot J,Peron JPS,Basso AS,Keller AC
16-0032-82 was used in Flow Cytometry to suggest that the modulation of the adrenergic signaling can be a complementary approach to αGC-based immunotherapy to mitigate iNKT-induced liver injury without compromising its antitumoral activity.
Fri Oct 20 00:00:00 EDT 2023
A single-cell atlas reveals the heterogeneity of meningeal immunity in a mouse model of Methyl CpG binding protein 2 deficiency.
Frontiers in immunology
Li H,Hu M,Huang Z,Wang Y,Xu Y,Deng J,Zhu M,Feng W,Xu X
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Immunohistochemistry
Tue Jan 31 00:00:00 EST 2023
LncRNA ANRIL-mediated miR-181b-5p/S1PR1 axis is involved in the progression of uremic cardiomyopathy through activating T cells.
Scientific reports
Xu Y,Cao L,Ji S,Shen W
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Thu Oct 27 00:00:00 EDT 2022
Estrogen Protects against Renal Ischemia-Reperfusion Injury by Regulating Th17/Treg Cell Immune Balance.
Disease markers
Zhang Y,Chang Y,Han Z,Ma K,Zeng X,Li L
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Tue Oct 18 00:00:00 EDT 2022
Therapeutic CFTR Correction Normalizes Systemic and Lung-Specific S1P Level Alterations Associated with Heart Failure.
International journal of molecular sciences
Uhl FE,Vanherle L,Matthes F,Meissner A
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Fri Jan 14 00:00:00 EST 2022
Loss of phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (Pip5k1c) in mesenchymal stem cells leads to osteopenia by impairing bone remodeling.
The Journal of biological chemistry
Yan Q,Gao H,Yao Q,Ling K,Xiao G
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2022
Bergenin, a PPARγ agonist, inhibits Th17 differentiation and subsequent neutrophilic asthma by preventing GLS1-dependent glutaminolysis.
Acta pharmacologica Sinica
Yang L,Zheng Y,Miao YM,Yan WX,Geng YZ,Dai Y,Wei ZF
16-0032-82 was used in Flow cytometry/Cell sorting to demonstrate a correlation existing among bergenin-affected GLS1-dependent glutaminolysis, PPARγ, CDK1-APC/C-Cdh1 signaling and Th17 differentiation.
Fri Apr 01 00:00:00 EDT 2022
Choroid plexus-selective inactivation of adenosine A2A receptors protects against T cell infiltration and experimental autoimmune encephalomyelitis.
Journal of neuroinflammation
Zheng W,Feng Y,Zeng Z,Ye M,Wang M,Liu X,Tang P,Shang H,Sun X,Lin X,Wang M,Li Z,Weng Y,Guo W,Vakal S,Chen JF
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Fri Feb 18 00:00:00 EST 2022
A reengineered common chain cytokine augments CD8+ T cell-dependent immunotherapy.
JCI insight
Banerjee A,Li D,Guo Y,Mei Z,Lau C,Chen K,Westwick J,Klauda JB,Schrum A,Lazear ER,Krupnick AS
16-0032-82 was used in Flow cytometry/Cell sorting to describe the signaling properties of a potentially unique cytokine by design, where T cell surface binding and signaling are separated between 2 different families of receptors.
Mon May 23 00:00:00 EDT 2022
Pannexin 1 channels facilitate communication between T cells to restrict the severity of airway inflammation.
Immunity
Medina CB,Chiu YH,Stremska ME,Lucas CD,Poon I,Tung KS,Elliott MR,Desai B,Lorenz UM,Bayliss DA,Ravichandran KS
16-0032-82 was used in Flow cytometry/Cell sorting to uncover an immunoregulatory role for the nucleotide release channel, Panx1, in T cell crosstalk during airway disease.
Tue Aug 10 00:00:00 EDT 2021
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions.
The Journal of experimental medicine
Ho TT,Dellorusso PV,Verovskaya EV,Bakker ST,Flach J,Smith LK,Ventura PB,Lansinger OM,Hérault A,Zhang SY,Kang YA,Mitchell CA,Villeda SA,Passegué E
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Intracellular aggregation of peptide-reprogrammed small molecule nanoassemblies enhances cancer chemotherapy and combinatorial immunotherapy.
Acta pharmaceutica Sinica. B
Peng J,Xiao Y,Yang Q,Liu Q,Chen Y,Shi K,Hao Y,Han R,Qian Z
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
PD-L1 overexpression conveys tolerance of mesenchymal stem cell-derived cardiomyocyte-like cells in an allogeneic mouse model.
Journal of cellular physiology
Mardomi A,Limoni SK,Rahbarghazi R,Mohammadi N,Khorashadizadeh M,Ranjbaran H,Nataj HH,Jafari N,Hasani B,Abediankenari S
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Immunohistochemistry
Wed Sep 01 00:00:00 EDT 2021
Early inflammation precedes cardiac fibrosis and heart failure in desmoglein 2 murine model of arrhythmogenic cardiomyopathy.
Cell and tissue research
Ng KE,Delaney PJ,Thenet D,Murtough S,Webb CM,Zaman N,Tsisanova E,Mastroianni G,Walker SLM,Westaby JD,Pennington DJ,Pink R,Kelsell DP,Tinker A
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Fri Oct 01 00:00:00 EDT 2021
Irradiated whole-cell vaccine suppresses hepatocellular carcinoma growth in mice via Th9 cells.
Oncology letters
Chen J,Ding Y,Huang F,Lan R,Wang Z,Huang W,Chen R,Wu B,Fu L,Yang Y,Liu J,Hong J,Zhang W,Zhang L
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
Neuroimmune Consequences of eIF4E Phosphorylation on Chemotherapy-Induced Peripheral Neuropathy.
Frontiers in immunology
Agalave NM,Mody PH,Szabo-Pardi TA,Jeong HS,Burton MD
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Mon Sep 20 00:00:00 EDT 2021
Alphavirus-Driven Interferon Gamma (IFNg) Expression Inhibits Tumor Growth in Orthotopic 4T1 Breast Cancer Model.
Vaccines
Trofimova O,Korotkaja K,Skrastina D,Jansons J,Spunde K,Isaguliants M,Zajakina A
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Wed Oct 27 00:00:00 EDT 2021
Functional inhibition of lactate dehydrogenase suppresses pancreatic adenocarcinoma progression.
Clinical and translational medicine
Cheng CS,Tan HY,Wang N,Chen L,Meng Z,Chen Z,Feng Y
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Immunohistochemistry (Paraffin)
Tue Jun 01 00:00:00 EDT 2021
Functional inhibition of lactate dehydrogenase suppresses pancreatic adenocarcinoma progression.
Clinical and translational medicine
Cheng CS,Tan HY,Wang N,Chen L,Meng Z,Chen Z,Feng Y
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Immunohistochemistry (Paraffin)
Tue Jun 01 00:00:00 EDT 2021
Molecular Mechanisms Underpinning the Circulation and Cellular Uptake of Mycobacterium ulcerans Toxin Mycolactone.
Frontiers in pharmacology
Tello Rubio B,Bugault F,Baudon B,Raynal B,Brûlé S,Morel JD,Saint-Auret S,Blanchard N,Demangel C,Guenin-Macé L
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Tue Oct 05 00:00:00 EDT 2021
Expression of CCRL2 Inhibits Tumor Growth by Concentrating Chemerin and Inhibiting Neoangiogenesis.
Cancers
Al Delbany D,Robert V,Dubois-Vedrenne I,Del Prete A,Vernimmen M,Radi A,Lefort A,Libert F,Wittamer V,Sozzani S,Parmentier M
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Immunohistochemistry
Tue Oct 05 00:00:00 EDT 2021
Small Molecule Potentiator of Adjuvant Activity Enhancing Survival to Influenza Viral Challenge.
Frontiers in immunology
Saito T,Sako Y,Sato-Kaneko F,Hosoya T,Yao S,Lao FS,Shpigelman J,Messer K,Pu M,Shukla NM,Chan M,Chu PJ,Cottam HB,Hayashi T,Carson DA,Corr M
16-0032-82 was used in Functional assays and Flow Cytometry to find that 2D216 augmented the beneficial protective immune responses of MPLA as a co-adjuvant and showed an excellent safety profile.
Fri Dec 10 00:00:00 EST 2021
Small Molecule Potentiator of Adjuvant Activity Enhancing Survival to Influenza Viral Challenge.
Frontiers in immunology
Saito T,Sako Y,Sato-Kaneko F,Hosoya T,Yao S,Lao FS,Shpigelman J,Messer K,Pu M,Shukla NM,Chan M,Chu PJ,Cottam HB,Hayashi T,Carson DA,Corr M
16-0032-82 was used in Functional assays and Flow Cytometry to find that 2D216 augmented the beneficial protective immune responses of MPLA as a co-adjuvant and showed an excellent safety profile.
Fri Dec 10 00:00:00 EST 2021
Gut Microbiota Dysbiosis Induced by Intracerebral Hemorrhage Aggravates Neuroinflammation in Mice.
Frontiers in microbiology
Yu X,Zhou G,Shao B,Zhou H,Xu C,Yan F,Wang L,Chen G,Li J,Fu X
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Wed May 26 00:00:00 EDT 2021
Type 1 Cytotoxic T Cells Increase in Placenta after Intrauterine Inflammation.
Frontiers in immunology
Liu J,Liu Y,Panda S,Liu A,Lei J,Burd I
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Fri Dec 17 00:00:00 EST 2021
STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.
Cellular and molecular gastroenterology and hepatology
Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Mon Jan 24 00:00:00 EST 2022
A mouse model for the study of anti-tumor T cell responses in Kras-driven lung adenocarcinoma.
Cell reports methods
Fitzgerald B,Connolly KA,Cui C,Fagerberg E,Mariuzza DL,Hornick NI,Foster GG,William I,Cheung JF,Joshi NS
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Immunocytochemistry
Mon Sep 27 00:00:00 EDT 2021
Inducible T-Cell Costimulator Mediates Lymphocyte/Macrophage Interactions During Liver Repair.
Frontiers in immunology
Ramavath NN,Gadipudi LL,Provera A,Gigliotti LC,Boggio E,Bozzola C,Albano E,Dianzani U,Sutti S
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Mon Feb 14 00:00:00 EST 2022
Soft implantable drug delivery device integrated wirelessly with wearable devices to treat fatal seizures.
Science advances
Joo H,Lee Y,Kim J,Yoo JS,Yoo S,Kim S,Arya AK,Kim S,Choi SH,Lu N,Lee HS,Kim S,Lee ST,Kim DH
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Immunohistochemistry
Fri Jan 01 00:00:00 EST 2021
Activation of mTORC1 at late endosomes misdirects T cell fate decision in older individuals.
Science immunology
Jin J,Kim C,Xia Q,Gould TM,Cao W,Zhang H,Li X,Weiskopf D,Grifoni A,Sette A,Weyand CM,Goronzy JJ
16-0032-82 was used in Cell Culture to show that lysosome-deficient T cells rely on late endosomes rather than lysosomes as an mTORC1 activation platform, where mTORC1 is activated by sensing cytosolic amino acids.
Fri Jun 18 00:00:00 EDT 2021
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2020
Contact-dependent delivery of IL-2 by dendritic cells to CD4 T cells in the contraction phase promotes their long-term survival.
Protein & cell
Tong D,Zhang L,Ning F,Xu Y,Hu X,Shi Y
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Sat Feb 01 00:00:00 EST 2020
Novel enhanced GFP-positive congenic inbred strain establishment and application of tumor-bearing nude mouse model.
Cancer science
Lan Q,Chen Y,Dai C,Li S,Fei X,Dong J,Shen Y,Dai X,Lu Z,Liu B,Wang Q,Wang H,Zhou Z,Ji X,Wang Z,Huang Q
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
In Situ Therapeutic Cancer Vaccination with an Oncolytic Virus Expressing Membrane-Tethered IL-2.
Molecular therapy oncolytics
Liu W,Dai E,Liu Z,Ma C,Guo ZS,Bartlett DL
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Fri Jun 26 00:00:00 EDT 2020
Loss of mural cell-derived laminin aggravates hemorrhagic brain injury.
Journal of neuroinflammation
Gautam J,Xu L,Nirwane A,Nguyen B,Yao Y
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Immunohistochemistry
Mon Apr 06 00:00:00 EDT 2020
Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target.
JCI insight
Pierini S,Tanyi JL,Simpkins F,George E,Uribe-Herranz M,Drapkin R,Burger R,Morgan MA,Facciabene A
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Thu Aug 20 00:00:00 EDT 2020
Stroma remodeling and reduced cell division define durable response to PD-1 blockade in melanoma.
Nature communications
Galvani E,Mundra PA,Valpione S,Garcia-Martinez P,Smith M,Greenall J,Thakur R,Helmink B,Andrews MC,Boon L,Chester C,Gremel G,Hogan K,Mandal A,Zeng K,Banyard A,Ashton G,Cook M,Lorigan P,Wargo JA,Dhomen N,Marais R
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Immunohistochemistry (Frozen)
Wed Feb 12 00:00:00 EST 2020
Triptolide Attenuates Transplant Vasculopathy Through Multiple Pathways.
Frontiers in immunology
Luo Z,Liao T,Zhang Y,Zheng H,Sun Q,Han F,Yang Z,Sun Q
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Thu Mar 25 00:00:00 EDT 2021
FOXO1 deficiency impairs proteostasis in aged T cells.
Science advances
Jin J,Li X,Hu B,Kim C,Cao W,Zhang H,Weyand CM,Goronzy JJ
16-0032 was used in Western Blotting to show that FOXO1 promotes lysosome function through the induction of the key transcription factor for lysosomal proteins, TFEB.
Wed Apr 01 00:00:00 EDT 2020
FOXO1 deficiency impairs proteostasis in aged T cells.
Science advances
Jin J,Li X,Hu B,Kim C,Cao W,Zhang H,Weyand CM,Goronzy JJ
16-0032 was used in Western Blotting to show that FOXO1 promotes lysosome function through the induction of the key transcription factor for lysosomal proteins, TFEB.
Wed Apr 01 00:00:00 EDT 2020
Developmental Dysfunction of the Central Nervous System Lymphatics Modulates the Adaptive Neuro-Immune Response in the Perilesional Cortex in a Mouse Model of Traumatic Brain Injury.
Frontiers in immunology
Wojciechowski S,Virenque A,Vihma M,Galbardi B,Rooney EJ,Keuters MH,Antila S,Koistinaho J,Noe FM
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Immunohistochemistry (Frozen)
Wed May 19 00:00:00 EDT 2021
Downregulation of Blimp1 inhibits the maturation of bone marrow-derived dendritic cells.
International journal of molecular medicine
Xiao J,Zhang J,Li X,Dai X,Wang J,He Y,Wei L,Shi J,Gong N
16-0032 was used in Flow cytometry/Cell sorting to demonstrate that transduction with lenti-shRNA-Blimp1 (lentiviral-mediated B-lymphocyte-induced maturation protein-1 shRNA) modulated the maturation of DCs via MHC-II molecule suppression and inhibited alloreactive T cell activation.
Fri Feb 01 00:00:00 EST 2019
Deletion of C-C Motif Chemokine Ligand 5 Worsens Invariant Natural Killer T-Cell-Mediated Hepatitis via Compensatory Up-regulation of CXCR2-Related Chemokine Activity.
Cellular and molecular gastroenterology and hepatology
Chen L,Gu J,Qian Y,Li M,Qian Y,Xu M,Li J,Wen Y,Xia L,Li J,Xia Q,Kong X,Wu H
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Tue Jun 04 00:00:00 EDT 2019
Blood autophagy defect causes accelerated non-hematopoietic organ aging.
Aging
Fang Y,Zhu L,An N,Jiang G,Qian J,Zhao R,Yuan N,Zhang S,Wang J
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Sun Jul 21 00:00:00 EDT 2019
MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment.
Journal for immunotherapy of cancer
Fang DD,Tang Q,Kong Y,Wang Q,Gu J,Fang X,Zou P,Rong T,Wang J,Yang D,Zhai Y
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Thu Nov 28 00:00:00 EST 2019
LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy.
Nature communications
Pascual-García M,Bonfill-Teixidor E,Planas-Rigol E,Rubio-Perez C,Iurlaro R,Arias A,Cuartas I,Sala-Hojman A,Escudero L,Martínez-Ricarte F,Huber-Ruano I,Nuciforo P,Pedrosa L,Marques C,Braña I,Garralda E,Vieito M,Squatrito M,Pineda E,Graus F,Espejo C,Sahuquillo J,Tabernero J,Seoane J
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Tue Jun 11 00:00:00 EDT 2019
Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.
Cell
Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Thu Jun 28 00:00:00 EDT 2018
Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.
Cell
Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Thu Jun 28 00:00:00 EDT 2018
Targeted delivery of immune therapeutics to lymph nodes prolongs cardiac allograft survival.
The Journal of clinical investigation
Bahmani B,Uehara M,Jiang L,Ordikhani F,Banouni N,Ichimura T,Solhjou Z,Furtmüller GJ,Brandacher G,Alvarez D,von Andrian UH,Uchimura K,Xu Q,Vohra I,Yilmam OA,Haik Y,Azzi J,Kasinath V,Bromberg JS,McGrath MM,Abdi R
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Western Blot
Thu Nov 01 00:00:00 EDT 2018
Targeted delivery of immune therapeutics to lymph nodes prolongs cardiac allograft survival.
The Journal of clinical investigation
Bahmani B,Uehara M,Jiang L,Ordikhani F,Banouni N,Ichimura T,Solhjou Z,Furtmüller GJ,Brandacher G,Alvarez D,von Andrian UH,Uchimura K,Xu Q,Vohra I,Yilmam OA,Haik Y,Azzi J,Kasinath V,Bromberg JS,McGrath MM,Abdi R
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Western Blot
Thu Nov 01 00:00:00 EDT 2018
Targeted delivery of immune therapeutics to lymph nodes prolongs cardiac allograft survival.
The Journal of clinical investigation
Bahmani B,Uehara M,Jiang L,Ordikhani F,Banouni N,Ichimura T,Solhjou Z,Furtmüller GJ,Brandacher G,Alvarez D,von Andrian UH,Uchimura K,Xu Q,Vohra I,Yilmam OA,Haik Y,Azzi J,Kasinath V,Bromberg JS,McGrath MM,Abdi R
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Western Blot
Thu Nov 01 00:00:00 EDT 2018
Impact of hyperglycemia on autoimmune pancreatitis and regulatory T-cells.
World journal of gastroenterology
Müller-Graff FT,Fitzner B,Jaster R,Vollmar B,Zechner D
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Sat Jul 28 00:00:00 EDT 2018
Neonatal adoptive transfer of lymphocytes rescues social behaviour during adolescence in immune-deficient mice.
The European journal of neuroscience
Clark SM,Vaughn CN,Soroka JA,Li X,Tonelli LH
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2018
CD4+ T cells are activated in regional lymph nodes and migrate to skin to initiate lymphedema.
Nature communications
García Nores GD,Ly CL,Cuzzone DA,Kataru RP,Hespe GE,Torrisi JS,Huang JJ,Gardenier JC,Savetsky IL,Nitti MD,Yu JZ,Rehal S,Mehrara BJ
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Thu May 17 00:00:00 EDT 2018
Microglia prevent peripheral immune cell invasion and promote an anti-inflammatory environment in the brain of APP-PS1 transgenic mice.
Journal of neuroinflammation
Unger MS,Schernthaner P,Marschallinger J,Mrowetz H,Aigner L
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Fri Sep 21 00:00:00 EDT 2018
Microbiota Reconstitution Does Not Cause Bone Loss in Germ-Free Mice.
mSphere
Quach D,Collins F,Parameswaran N,McCabe L,Britton RA
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias.
Nature communications
Chaudhury S,O'Connor C,Cañete A,Bittencourt-Silvestre J,Sarrou E,Prendergast Á,Choi J,Johnston P,Wells CA,Gibson B,Keeshan K
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Tue Dec 11 00:00:00 EST 2018
Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias.
Nature communications
Chaudhury S,O'Connor C,Cañete A,Bittencourt-Silvestre J,Sarrou E,Prendergast Á,Choi J,Johnston P,Wells CA,Gibson B,Keeshan K
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Tue Dec 11 00:00:00 EST 2018
Myeloid apolipoprotein E controls dendritic cell antigen presentation and T cell activation.
Nature communications
Bonacina F,Coe D,Wang G,Longhi MP,Baragetti A,Moregola A,Garlaschelli K,Uboldi P,Pellegatta F,Grigore L,Da Dalt L,Annoni A,Gregori S,Xiao Q,Caruso D,Mitro N,Catapano AL,Marelli-Berg FM,Norata GD
16-0032 was used in Flow cytometry/Cell sorting to show that apolipoprotein E deficiency leads to the accumulation of cholesterol in the cell membrane of dendritic cells, resulting in enhanced MHC-II-dependent antigen presentation and CD4+ T-cell activation.
Mon Aug 06 00:00:00 EDT 2018
Regulatory Innate Lymphoid Cells Control Innate Intestinal Inflammation.
Cell
Wang S,Xia P,Chen Y,Qu Y,Xiong Z,Ye B,Du Y,Tian Y,Yin Z,Xu Z,Fan Z
16-0032 was used in Flow cytometry/Cell sorting to identify a regulatory subpopulation of innate lymphoid cells that exists in the gut, and harbour a unique gene identity.
Thu Sep 21 00:00:00 EDT 2017
Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis.
Immunity
Kishore M,Cheung KCP,Fu H,Bonacina F,Wang G,Coe D,Ward EJ,Colamatteo A,Jangani M,Baragetti A,Matarese G,Smith DM,Haas R,Mauro C,Wraith DC,Okkenhaug K,Catapano AL,De Rosa V,Norata GD,Marelli-Berg FM
16-0032 was used in Functional assays to demonstrate that glucokinase-dependent glycolysis regulates regulatory T cell migration.
Tue Nov 21 00:00:00 EST 2017
Characterization of meningeal type 2 innate lymphocytes and their response to CNS injury.
The Journal of experimental medicine
Gadani SP,Smirnov I,Wiltbank AT,Overall CC,Kipnis J
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Immunofluorescence
Wed Feb 01 00:00:00 EST 2017
Anti-CD137 Suppresses Tumor Growth by Blocking Reverse Signaling by CD137 Ligand.
Cancer research
Kang SW,Lee SC,Park SH,Kim J,Kim HH,Lee HW,Seo SK,Kwon BS,Cho HR,Kwon B
16-0032-82 was used in Flow Cytometry to report findings related to reverse signaling by CD137 ligand (CD137L) in antigen-presenting dendritic cells (DC) in tumors that address these paradoxical results.
Wed Nov 01 00:00:00 EDT 2017
1810011o10 Rik Inhibits the Antitumor Effect of Intratumoral CD8+ T Cells through Suppression of Notch2 Pathway in a Murine Hepatocellular Carcinoma Model.
Frontiers in immunology
Dai K,Huang L,Huang YB,Chen ZB,Yang LH,Jiang YA
16-0032 was used in Functional assays to disclose a novel mechanism underlying the negative regulation of antitumour CD8(+) T cells during HCC progression.
Wed Nov 20 00:00:00 EST 2019
Diet-induced obesity causes visceral, but not subcutaneous, lymph node hyperplasia via increases in specific immune cell populations.
Cell proliferation
Magnuson AM,Regan DP,Fouts JK,Booth AD,Dow SW,Foster MT
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Immunocytochemistry
Sun Oct 01 00:00:00 EDT 2017
Silybin attenuates LPS-induced lung injury in mice by inhibiting NF-κB signaling and NLRP3 activation.
International journal of molecular medicine
Zhang B,Wang B,Cao S,Wang Y,Wu D
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2017
Effect of Early-life Gut Mucosal Compromise on Disease Progression in NOD Mice.
Comparative medicine
Bendtsen KM,Hansen CH,Krych L,Buschard K,Farlov H,Hansen AK
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Sun Oct 01 00:00:00 EDT 2017
Recipient bone marrow assimilates the myeloid/lymphoid reconstitution of distinct fetal hematopoietic stem cells.
Oncotarget
Guo XL,Chu L,Ke F,Mu LL,Li Z,Cai JJ,Li HF,Hong DL
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Tue Dec 12 00:00:00 EST 2017
Stimulation of hair follicle stem cell proliferation through an IL-1 dependent activation of γδT-cells.
eLife
Lee P,Gund R,Dutta A,Pincha N,Rana I,Ghosh S,Witherden D,Kandyba E,MacLeod A,Kobielak K,Havran WL,Jamora C
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in T-Cell Activation
Mon Dec 04 00:00:00 EST 2017
Stimulation of hair follicle stem cell proliferation through an IL-1 dependent activation of γδT-cells.
eLife
Lee P,Gund R,Dutta A,Pincha N,Rana I,Ghosh S,Witherden D,Kandyba E,MacLeod A,Kobielak K,Havran WL,Jamora C
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in T-Cell Activation
Mon Dec 04 00:00:00 EST 2017
Loss of epidermal AP1 transcription factor function reduces filaggrin level, alters chemokine expression and produces an ichthyosis-related phenotype.
Cell death & disease
Young CA,Rorke EA,Adhikary G,Xu W,Eckert RL
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2017
Tristetraprolin inhibits macrophage IL-27-induced activation of antitumour cytotoxic T cell responses.
Nature communications
Wang Q,Ning H,Peng H,Wei L,Hou R,Hoft DF,Liu J
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Wed Oct 11 00:00:00 EDT 2017
Rottlerin as a therapeutic approach in psoriasis: Evidence from in vitro and in vivo studies.
PloS one
Min M,Yan BX,Wang P,Landeck L,Chen JQ,Li W,Cai SQ,Zheng M,Man XY
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Tue Jan 16 00:00:00 EST 2018
The breast tumor microenvironment alters the phenotype and function of natural killer cells.
Cellular & molecular immunology
Krneta T,Gillgrass A,Chew M,Ashkar AA
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
Laminin regulates PDGFRβ(+) cell stemness and muscle development.
Nature communications
Yao Y,Norris EH,Mason CE,Strickland S
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Immunofluorescence
Tue May 03 00:00:00 EDT 2016
CD8(+) T-cell Immune Evasion Enables Oncolytic Virus Immunotherapy.
EBioMedicine
Pourchet A,Fuhrmann SR,Pilones KA,Demaria S,Frey AB,Mulvey M,Mohr I
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation.
Nature communications
Yang M,Chen S,Du J,He J,Wang Y,Li Z,Liu G,Peng W,Zeng X,Li D,Xu P,Guo W,Chang Z,Wang S,Tian Z,Dong Z
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Wed Sep 07 00:00:00 EDT 2016
TNF-Mediated Restriction of Arginase 1 Expression in Myeloid Cells Triggers Type 2 NO Synthase Activity at the Site of Infection.
Cell reports
Schleicher U,Paduch K,Debus A,Obermeyer S,König T,Kling JC,Ribechini E,Dudziak D,Mougiakakos D,Murray PJ,Ostuni R,Körner H,Bogdan C
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Tue May 03 00:00:00 EDT 2016
Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine.
Scientific reports
Ochi T,Feng Y,Kitamoto S,Nagao-Kitamoto H,Kuffa P,Atarashi K,Honda K,Teitelbaum DH,Kamada N
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Wed Jun 15 00:00:00 EDT 2016
Pulsed low-dose RANKL as a potential therapeutic for postmenopausal osteoporosis.
JCI insight
Cline-Smith A,Gibbs J,Shashkova E,Buchwald ZS,Novack DV,Aurora R
16-0032 was used in Flow cytometry/Cell sorting to study how pulsing low doses of RANKL induces TcREG, which provides a potential treatment for postmenopausal osteoporosis.
Thu Aug 18 00:00:00 EDT 2016
High salt reduces the activation of IL-4- and IL-13-stimulated macrophages.
The Journal of clinical investigation
Binger KJ,Gebhardt M,Heinig M,Rintisch C,Schroeder A,Neuhofer W,Hilgers K,Manzel A,Schwartz C,Kleinewietfeld M,Voelkl J,Schatz V,Linker RA,Lang F,Voehringer D,Wright MD,Hubner N,Dechend R,Jantsch J,Titze J,Müller DN
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Mon Nov 02 00:00:00 EST 2015
IKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis.
The Journal of experimental medicine
Pallangyo CK,Ziegler PK,Greten FR
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Mon Dec 14 00:00:00 EST 2015
Protection in antibody- and T cell-mediated autoimmune diseases by antiinflammatory IgG Fcs requires type II FcRs.
Proceedings of the National Academy of Sciences of the United States of America
Fiebiger BM,Maamary J,Pincetic A,Ravetch JV
16-0032 was used in Flow cytometry/Cell sorting to demonstrate that Fc variants that mimic the structural alterations induced by sialylation are candidates for the treatment of autoimmune disorders.
Tue May 05 00:00:00 EDT 2015
Role of caveolin-3 in lymphocyte activation.
Life sciences
Tran C,Stary CM,Schilling JM,Bentley B,Patel HH,Roth DM
16-0032 was used in Functional assays to demonstrate that Cav-3 may be a novel participant in B-cell expression, T-cell cytokine production and activation of inflammation.
Thu Jan 15 00:00:00 EST 2015
A Bone Anabolic Effect of RANKL in a Murine Model of Osteoporosis Mediated Through FoxP3+ CD8 T Cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Buchwald ZS,Yang C,Nellore S,Shashkova EV,Davis JL,Cline A,Ko J,Novack DV,DiPaolo R,Aurora R
16-0032 was used in Flow cytometry/Cell sorting to study the bone anabolic effect of receptor activator of NF-κB ligand in a murine model of osteoporosis.
Sat Aug 01 00:00:00 EDT 2015
Adjuvants may reduce in vivo transfection levels for DNA vaccination in mice leading to reduced antigen-specific CD8+ T cell responses.
Human vaccines & immunotherapeutics
Rose AH,Hoffmann FW,Hara JH,Urschitz J,Moisyadi S,Hoffmann PR,Bertino P
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Mon May 16 00:00:00 EDT 2016
IL-33 Enhances Humoral Immunity Against Chronic HBV Infection Through Activating CD4(+)CXCR5(+) TFH Cells.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Zhao PW,Shi X,Li C,Ayana DA,Niu JQ,Feng JY,Wang J,Jiang YF
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2015
Development of a graded index microlens based fiber optical trap and its characterization using principal component analysis.
Biomedical optics express
Nylk J,Kristensen MV,Mazilu M,Thayil AK,Mitchell CA,Campbell EC,Powis SJ,Gunn-Moore FJ,Dholakia K
16-0032 was used in Functional assays to demonstrate a miniaturised optical trapping probe for use in optically-mediated immunological synapse formation.
Wed Apr 01 00:00:00 EDT 2015
Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling.
Nature communications
Kang YJ,Bang BR,Han KH,Hong L,Shim EJ,Ma J,Lerner RA,Otsuka M
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Fri Sep 18 00:00:00 EDT 2015
Antibiotics in neonatal life increase murine susceptibility to experimental psoriasis.
Nature communications
Zanvit P,Konkel JE,Jiao X,Kasagi S,Zhang D,Wu R,Chia C,Ajami NJ,Smith DP,Petrosino JF,Abbatiello B,Nakatsukasa H,Chen Q,Belkaid Y,Chen ZJ,Chen W
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Tue Sep 29 00:00:00 EDT 2015
Expression of the Receptor Tyrosine Kinase EphB2 on Dendritic Cells Is Modulated by Toll-Like Receptor Ligation but Is Not Required for T Cell Activation.
PloS one
Mimche PN,Brady LM,Keeton S,Fenne DS,King TP,Quicke KM,Hudson LE,Lamb TJ
16-0032 was used in Flow cytometry/Cell sorting to investigate the contribution of Ephrin B2 to dendritic cell responses.
Wed Jun 01 00:00:00 EDT 2016
Characterization of conventional and atypical receptors for the chemokine CCL2 on mouse leukocytes.
Journal of immunology (Baltimore, Md. : 1950)
Ford LB,Cerovic V,Milling SW,Graham GJ,Hansell CA,Nibbs RJ
16-0032 was used in Flow cytometry/Cell sorting to define the expression profile, scavenging activity, and ligand specificity of CCL2 receptors on mouse leukocytes.
Tue Jul 01 00:00:00 EDT 2014
A chitin-like component on sclerotic cells of Fonsecaea pedrosoi inhibits Dectin-1-mediated murine Th17 development by masking β-glucans.
PloS one
Dong B,Li D,Li R,Chen SC,Liu W,Liu W,Chen L,Chen Y,Zhang X,Tong Z,Xia Y,Xia P,Wang Y,Duan Y
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2015
Leukocyte population dynamics and detection of IL-9 as a major cytokine at the mouse fetal-maternal interface.
PloS one
Habbeddine M,Verbeke P,Karaz S,Bobé P,Kanellopoulos-Langevin C
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Wed Jun 10 00:00:00 EDT 2015
Interferon gamma causes olfactory dysfunction without concomitant neuroepithelial damage.
International forum of allergy & rhinology
Pozharskaya T,Lane AP
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Immunohistochemistry
Fri Nov 01 00:00:00 EDT 2013
Osteoclast-induced Foxp3+ CD8 T-cells limit bone loss in mice.
Bone
Buchwald ZS,Kiesel JR,Yang C,DiPaolo R,Novack DV,Aurora R
16-0032 was used in Flow cytometry/Cell sorting to provide in vivo evidence that osteoclast-induced Treg cells have anti-resorptive activity and repress the immune system.
Sun Sep 01 00:00:00 EDT 2013
Neuronal and nonneuronal cholinergic structures in the mouse gastrointestinal tract and spleen.
The Journal of comparative neurology
Gautron L,Rutkowski JM,Burton MD,Wei W,Wan Y,Elmquist JK
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Immunofluorescence
Fri Nov 01 00:00:00 EDT 2013
Prenatal cadmium exposure alters postnatal immune cell development and function.
Toxicology and applied pharmacology
Hanson ML,Holásková I,Elliott M,Brundage KM,Schafer R,Barnett JB
16-0032 was used in Functional assays to investigate the effects of prenatal exposure to Cd on the immune system of offspring, showing that exposure alters postnatal immune cell development and function.
Fri Jun 01 00:00:00 EDT 2012
Optimal isolation of functional Foxp3+ induced regulatory T cells using DEREG mice.
PloS one
Baru AM,Untucht C,Ganesh V,Hesse C,Mayer CT,Sparwasser T
16-0032 was used in Flow cytometry/Cell sorting to define culture conditions for efficient generation of eGFP(+)Foxp3(+) iTregs by use of DEREG mice.
Thu Feb 14 00:00:00 EST 2013
CpG and non-CpG oligodeoxynucleotides directly costimulate mouse and human CD4+ T cells through a TLR9- and MyD88-independent mechanism.
Journal of immunology (Baltimore, Md. : 1950)
Landrigan A,Wong MT,Utz PJ
16-0032 was used in Functional assays to study the ability of oligodeoxynucleotides to activate and polarise T cells.
Thu Sep 15 00:00:00 EDT 2011
Increased incidence of endometrioid tumors caused by aberrations in E-cadherin promoter of mismatch repair-deficient mice.
Carcinogenesis
Kovtun IV,Harris KJ,Jatoi A,Jevremovic D
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Immunohistochemistry
Fri Jul 01 00:00:00 EDT 2011
Auf1/Hnrnpd-deficient mice develop pruritic inflammatory skin disease.
The Journal of investigative dermatology
Sadri N,Schneider RJ
Published figure using CD3 monoclonal antibody (Product # 16-0032-82) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2009
