Product References
FGFR inhibition augments anti-PD-1 efficacy in murine FGFR3-mutant bladder cancer by abrogating immunosuppression.
The Journal of clinical investigation
Okato A,Utsumi T,Ranieri M,Zheng X,Zhou M,Pereira LD,Chen T,Kita Y,Wu D,Hyun H,Lee H,Gdowski AS,Raupp JD,Clark-Garvey S,Manocha U,Chafitz A,Sherman F,Stephens J,Rose TL,Milowsky MI,Wobker SE,Serody JS,Damrauer JS,Wong KK,Kim WY
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Tue Jan 16 00:00:00 UTC 2024
Toxin expression during Staphylococcus aureus infection imprints host immunity to inhibit vaccine efficacy.
NPJ vaccines
Teymournejad O,Li Z,Beesetty P,Yang C,Montgomery CP
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Tue Jan 24 00:00:00 UTC 2023
NCR negative group 3 innate lymphoid cell (NCR- ILC3) participates in abnormal pathology of lung in cigarette smoking-induced COPD mice.
Immunity, inflammation and disease
Chu S,Ma L,Yang X,Xiao B,Liang Y,Zheng S,Li L
17-0031-82 was used in Flow cytometry/Cell sorting to investigate the role of Natural Cytotoxicity Receptor negative innate lymphoid cells (NCR- ILC3) in the pathogenesis of chronic obstructive pulmonary disease (COPD) induced by cigarette smoking.
Wed Mar 01 00:00:00 UTC 2023
NCR negative group 3 innate lymphoid cell (NCR- ILC3) participates in abnormal pathology of lung in cigarette smoking-induced COPD mice.
Immunity, inflammation and disease
Chu S,Ma L,Yang X,Xiao B,Liang Y,Zheng S,Li L
17-0031-82 was used in Flow cytometry/Cell sorting to investigate the role of Natural Cytotoxicity Receptor negative innate lymphoid cells (NCR- ILC3) in the pathogenesis of chronic obstructive pulmonary disease (COPD) induced by cigarette smoking.
Wed Mar 01 00:00:00 UTC 2023
Myeloid-intrinsic cell cycle-related kinase drives immunosuppression to promote tumorigenesis.
iScience
Zhou J,Wang H,Shu T,Wang J,Yang W,Li J,Ding L,Liu M,Sun H,Wong J,Lai PB,Tsang SW,Ward SE,Chow KL,Sung JJ,Sze-Lok Cheng A
17-0031-82 was used in Flow cytometry/Cell sorting to demonstrated that cell cycle-related kinase (CCRK) is upregulated in myeloid cells in tumor-bearing mice and in patients with hepatocellular carcinoma.
Fri Oct 20 00:00:00 UTC 2023
Mammary γδ T cells promote IL-17A-mediated immunity against Staphylococcus aureus-induced mastitis in a microbiota-dependent manner.
iScience
Pan N,Xiu L,Xu Y,Bao X,Liang Y,Zhang H,Liu B,Feng Y,Guo H,Wu J,Li H,Ma C,Sheng S,Wang T,Wang X
17-0031-82 was used in Flow Cytometry to find that neutrophil recruitment via IL-17A-mediated signaling was required for host defense against S. aureus-induced mastitis in a mouse model.
Fri Dec 15 00:00:00 UTC 2023
Novel RNA polymerase I inhibitor CX-5461 suppresses imiquimod-induced experimental psoriasis.
Experimental dermatology
Wu X,Yin Q,Wang J,Dai C,Wang J,Guo X,Jiang F
17-0031-82 was used in Flow Cytometry to demonstrate that topical application of CX-5461 prevented the development of imiquimod-induced psoriasis, with decreases in keratinocyte proliferation, T-cell infiltration and pathological angiogenesis.
Sun Jan 01 00:00:00 UTC 2023
Molecular Imaging of Oxygenation Changes during Immunotherapy in Combination with Paclitaxel in Triple Negative Breast Cancer.
Biomedicines
Napier TS,Lynch SE,Lu Y,Song PN,Burns AC,Sorace AG
17-0031-82 was used in Flow cytometry/Cell sorting to provide insights into how PEF protein dynamics affect secretion of important physiological cargoes such as collagen I and significantly impact ER stress.
Wed Jan 04 00:00:00 UTC 2023
Adipocyte-Secreted IL-6 Sensitizes Macrophages to IL-4 Signaling.
Diabetes
Luan D,Dadpey B,Zaid J,Bridge-Comer PE,DeLuca JH,Xia W,Castle J,Reilly SM
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Wed Mar 01 00:00:00 UTC 2023
Stem cell architecture drives myelodysplastic syndrome progression and predicts response to venetoclax-based therapy.
Nature medicine
Ganan-Gomez I,Yang H,Ma F,Montalban-Bravo G,Thongon N,Marchica V,Richard-Carpentier G,Chien K,Manyam G,Wang F,Alfonso A,Chen S,Class C,Kanagal-Shamanna R,Ingram JP,Ogoti Y,Rose A,Loghavi S,Lockyer P,Cambo B,Muftuoglu M,Schneider S,Adema V,McLellan M,Garza J,Marchesini M,Giuliani N,Pellegrini M,Wang J,Walker J,Li Z,Takahashi K,Leverson JD,Bueso-Ramos C,Andreeff M,Clise-Dwyer K,Garcia-Manero G,Colla S
17-0031-82 was used in Flow Cytometry to study the biological mechanisms that drive hypomethylating agent therapy failure at the stem-cell level to uncover vulnerabilities in the disease and halt its evolution.
Tue Mar 01 00:00:00 UTC 2022
Impaired mitochondrial oxidative metabolism in skeletal progenitor cells leads to musculoskeletal disintegration.
Nature communications
Lin C,Yang Q,Guo D,Xie J,Yang YS,Chaugule S,DeSouza N,Oh WT,Li R,Chen Z,John AA,Qiu Q,Zhu LJ,Greenblatt MB,Ghosh S,Li S,Gao G,Haynes C,Emerson CP,Shim JH
17-0031-82 was used in Flow cytometry/Cell sorting to identify mitochondrial oxidative phosphorylation as the prominent energy-driving force for osteogenesis of skeletal progenitors, governing musculoskeletal integrity.
Fri Nov 11 00:00:00 UTC 2022
Image-seq: spatially resolved single-cell sequencing guided by in situ and in vivo imaging.
Nature methods
Haase C,Gustafsson K,Mei S,Yeh SC,Richter D,Milosevic J,Turcotte R,Kharchenko PV,Sykes DB,Scadden DT,Lin CP
17-0031-82 was used in Flow cytometry/Cell sorting to present Image-seq, a technology that provides single-cell transcriptional data on cells that are isolated from specific spatial locations under image guidance, thus preserving the spatial information of the target cells.
Thu Dec 01 00:00:00 UTC 2022
Stromal Reprogramming by FAK Inhibition Overcomes Radiation Resistance to Allow for Immune Priming and Response to Checkpoint Blockade.
Cancer discovery
Lander VE,Belle JI,Kingston NL,Herndon JM,Hogg GD,Liu X,Kang LI,Knolhoff BL,Bogner SJ,Baer JM,Zuo C,Borcherding NC,Lander DP,Mpoy C,Scott J,Zahner M,Rogers BE,Schwarz JK,Kim H,DeNardo DG
17-0031-82 was used in Flow Cytometry to show that FAK inhibition allows RT to prime tumor immunity and unlock responsiveness to checkpoint immunotherapy.
Fri Dec 02 00:00:00 UTC 2022
A novel Cytochrome P450 26A1 expressing NK cell subset at the mouse maternal-foetal interface.
Journal of cellular and molecular medicine
Wei DP,Li DD,Gu AQ,Ji WH,Yang Y,Peng JP
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Mon Feb 01 00:00:00 UTC 2021
Construction of a 3D brain extracellular matrix model to study the interaction between microglia and T cells in co-culture.
The European journal of neuroscience
Frühauf M,Zeitschel U,Höfling C,Ullm F,Rabiger FV,Alber G,Pompe T,Müller U,Roßner S
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Tue Jun 01 00:00:00 UTC 2021
Construction of a 3D brain extracellular matrix model to study the interaction between microglia and T cells in co-culture.
The European journal of neuroscience
Frühauf M,Zeitschel U,Höfling C,Ullm F,Rabiger FV,Alber G,Pompe T,Müller U,Roßner S
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Tue Jun 01 00:00:00 UTC 2021
Imbalance between T helper 1 and regulatory T cells plays a detrimental role in experimental Parkinson's disease in mice.
The Journal of international medical research
Li W,Luo Y,Xu H,Ma Q,Yao Q
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Thu Apr 01 00:00:00 UTC 2021
Effective delivery of STING agonist using exosomes suppresses tumor growth and enhances antitumor immunity.
The Journal of biological chemistry
McAndrews KM,Che SPY,LeBleu VS,Kalluri R
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Fri Aug 20 00:00:00 UTC 2021
The effect of fingolimod on regulatory T cells in a mouse model of brain ischaemia.
Journal of neuroinflammation
Malone K,Diaz Diaz AC,Shearer JA,Moore AC,Waeber C
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Sat Jan 30 00:00:00 UTC 2021
Obesity results in adipose tissue T cell exhaustion.
JCI insight
Porsche CE,Delproposto JB,Geletka L,O'Rourke R,Lumeng CN
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Thu Apr 22 00:00:00 UTC 2021
Theranostic near-infrared-IIb emitting nanoprobes for promoting immunogenic radiotherapy and abscopal effects against cancer metastasis.
Nature communications
Li H,Wang M,Huang B,Zhu SW,Zhou JJ,Chen DR,Cui R,Zhang M,Sun ZJ
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Thu Dec 09 00:00:00 UTC 2021
Hypoxia-sensing CAR T cells provide safety and efficacy in treating solid tumors.
Cell reports. Medicine
Kosti P,Opzoomer JW,Larios-Martinez KI,Henley-Smith R,Scudamore CL,Okesola M,Taher MYM,Davies DM,Muliaditan T,Larcombe-Young D,Woodman N,Gillett CE,Thavaraj S,Maher J,Arnold JN
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Tue Apr 20 00:00:00 UTC 2021
Non-redundant activity of GSK-3α and GSK-3β in T cell-mediated tumor rejection.
iScience
Steele L,Mannion AJ,Shaw G,Maclennan KA,Cook GP,Rudd CE,Taylor A
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Fri Jun 25 00:00:00 UTC 2021
Non-redundant activity of GSK-3α and GSK-3β in T cell-mediated tumor rejection.
iScience
Steele L,Mannion AJ,Shaw G,Maclennan KA,Cook GP,Rudd CE,Taylor A
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Fri Jun 25 00:00:00 UTC 2021
Loss of fragile site-associated tumor suppressor promotes antitumor immunity via macrophage polarization.
Nature communications
Zhang L,Zhang K,Zhang J,Zhu J,Xi Q,Wang H,Zhang Z,Cheng Y,Yang G,Liu H,Guo X,Zhou D,Xue Z,Li Y,Zhang Q,Da Y,Liu L,Yin Z,Yao Z,Zhang R
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Wed Jul 14 00:00:00 UTC 2021
Histological, behavioural and flow cytometric datasets relating to acute ischaemic stroke in young, aged and ApoE-/- mice in the presence and absence of immunomodulation with fingolimod.
Data in brief
Diaz Diaz AC,Malone K,Shearer JA,Moore AC,Waeber C
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Tue Jun 01 00:00:00 UTC 2021
Targeting Ovarian Carcinoma with TSP-1:CD47 Antagonist TAX2 Activates Anti-Tumor Immunity.
Cancers
Jeanne A,Sarazin T,Charlé M,Moali C,Fichel C,Boulagnon-Rombi C,Callewaert M,Andry MC,Diesis E,Delolme F,Rioult D,Dedieu S
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Thu Oct 07 00:00:00 UTC 2021
A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis.
Nature communications
Wang G,Xie L,Li B,Sang W,Yan J,Li J,Tian H,Li W,Zhang Z,Tian Y,Dai Y
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Thu Sep 30 00:00:00 UTC 2021
Smek1 deficiency exacerbates experimental autoimmune encephalomyelitis by activating proinflammatory microglia and suppressing the IDO1-AhR pathway.
Journal of neuroinflammation
Duan RN,Yang CL,Du T,Liu A,Wang AR,Sun WJ,Li X,Li JX,Yan CZ,Liu QJ
17-0031-82 was used in Flow Cytometry to provide an instructive basis for the roles of Smek1 in EAE and broaden the understanding of the genetic factors involved in the pathogenesis of autoimmune demyelination.
Mon Jun 28 00:00:00 UTC 2021
tiRNA signaling via stress-regulated vesicle transfer in the hematopoietic niche.
Cell stem cell
Kfoury YS,Ji F,Mazzola M,Sykes DB,Scherer AK,Anselmo A,Akiyama Y,Mercier F,Severe N,Kokkaliaris KD,Zhao T,Brouse T,Saez B,Seidl J,Papazian A,Ivanov P,Mansour MK,Sadreyev RI,Scadden DT
17-0031-82 was used in Flow cytometry/Cell sorting to show that extracellular vesicle-mediated tiRNA transfer provides a stress-modulated signalling axis, distinct from conventional stress responses, in the bone marow niche.
Thu Dec 02 00:00:00 UTC 2021
PP2Cδ Controls the Differentiation and Function of Dendritic Cells Through Regulating the NSD2/mTORC2/ACLY Pathway.
Frontiers in immunology
Lv N,Jin S,Liang Z,Wu X,Kang Y,Su L,Dong Y,Wang B,Ma T,Shi L
17-0031-82 was used in Flow Cytometry to show that the phosphatase PP2Cδ played a pivotal role in regulating dendritic cells (DC) activation and function, as PP2Cδ ablation caused aberrant maturation, activation, and Th1/Th17-priming of DCs, and hence induced onset of exacerbated experimental autoimmune encephalomyelitis.
Mon Feb 28 00:00:00 UTC 2022
Combined Prebiotic and Microbial Intervention Improves Oral Cholera Vaccination Responses in a Mouse Model of Childhood Undernutrition.
Cell host & microbe
Di Luccia B,Ahern PP,Griffin NW,Cheng J,Guruge JL,Byrne AE,Rodionov DA,Leyn SA,Osterman AL,Ahmed T,Colonna M,Barratt MJ,Delahaye NF,Gordon JI
17-0031-82 was used in Flow Cytometry to provide preclinical proof-of-concept that diet and microbiota influence mucosal immune responses to CT vaccination and identify a candidate synbiotic formulation.
Wed Jun 10 00:00:00 UTC 2020
Potently Cytotoxic Natural Killer Cells Initially Emerge from Erythro-Myeloid Progenitors during Mammalian Development.
Developmental cell
Dege C,Fegan KH,Creamer JP,Berrien-Elliott MM,Luff SA,Kim D,Wagner JA,Kingsley PD,McGrath KE,Fehniger TA,Palis J,Sturgeon CM
17-0031 was used in Flow cytometry/Cell sorting to identify an extra-embryonic origin of potently cytotoxic NK cells, suggesting that ontogenic origin is a relevant factor in designing hPSC-derived adoptive immunotherapies.
Mon Apr 20 00:00:00 UTC 2020
Excessive Costimulation Leads to Dysfunction of Adoptively Transferred T Cells.
Cancer immunology research
Wijewarnasuriya D,Bebernitz C,Lopez AV,Rafiq S,Brentjens RJ
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Mon Jun 01 00:00:00 UTC 2020
Critical role of OX40 in drug-induced acute liver injury.
British journal of pharmacology
Zhang C,Jin H,Wang Y,Li C,Zhao X,Li Y,Shi W,Tian Y,Xu H,Tian D,Liu K,Jia J,Sun G,Zhang D
17-0031-82 was used in Flow Cytometry to show that OX40 is a key molecule that promotes both pro-inflammatory macrophage and CD4+ T-cell function, exacerbating paracetamol-induced liver injury.
Wed Jul 01 00:00:00 UTC 2020
Senescence-associated secretory phenotype promotes chronic ocular graft-vs-host disease in mice and humans.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Yamane M,Sato S,Shimizu E,Shibata S,Hayano M,Yaguchi T,Kamijuku H,Ogawa M,Suzuki T,Mukai S,Shimmura S,Okano H,Takeuchi T,Kawakami Y,Ogawa Y,Tsubota K
17-0031-82 was used in Immunohistochemistry to elucidate an additional pathway of chronic ocular chronic graft-vs-host disease.
Sat Aug 01 00:00:00 UTC 2020
Antitumor Effect and Immune Response of Nanosecond Pulsed Electric Fields in Pancreatic Cancer.
Frontiers in oncology
Zhao J,Chen S,Zhu L,Zhang L,Liu J,Xu D,Tian G,Jiang T
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Fri Oct 28 00:00:00 UTC 2022
Enhanced alleviation of aGVHD by TGF-β1-modified mesenchymal stem cells in mice through shifting MΦ into M2 phenotype and promoting the differentiation of Treg cells.
Journal of cellular and molecular medicine
Wu R,Liu C,Deng X,Chen L,Hao S,Ma L
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Wed Jan 01 00:00:00 UTC 2020
DEK-targeting aptamer DTA-64 attenuates bronchial EMT-mediated airway remodelling by suppressing TGF-β1/Smad, MAPK and PI3K signalling pathway in asthma.
Journal of cellular and molecular medicine
Song Y,Wang Z,Jiang J,Piao Y,Li L,Xu C,Piao H,Li L,Yan G
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Tue Dec 01 00:00:00 UTC 2020
Impact of S1P Mimetics on Mesenteric Ischemia/Reperfusion Injury.
Pharmaceuticals (Basel, Switzerland)
Potì F,Giorgio C,Zini I,Nofer JR,Vivo V,Palese S,Ballabeni V,Barocelli E,Bertoni S
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Fri Oct 09 00:00:00 UTC 2020
CD279 mediates the homeostasis and survival of regulatory T cells by enhancing T cell and macrophage interactions.
FEBS open bio
Liu Y,Gao Y,Hao H,Hou T
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Mon Jun 01 00:00:00 UTC 2020
TNFAIP3 Plays a Role in Aging of the Hematopoietic System.
Frontiers in immunology
Smith MA,Culver-Cochran AE,Adelman ER,Rhyasen GW,Ma A,Figueroa ME,Starczynowski DT
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Wed Apr 28 00:00:00 UTC 2021
IDO1+ Paneth cells promote immune escape of colorectal cancer.
Communications biology
Pflügler S,Svinka J,Scharf I,Crncec I,Filipits M,Charoentong P,Tschurtschenthaler M,Kenner L,Awad M,Stift J,Schernthanner M,Bischl R,Herndler-Brandstetter D,Glitzner E,Moll HP,Casanova E,Timelthaler G,Sibilia M,Gnant M,Lax S,Thaler J,Müller M,Strobl B,Mohr T,Kaser A,Trajanoski Z,Heller G,Eferl R
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Fri May 22 00:00:00 UTC 2020
TET2-Loss-of-Function-Driven Clonal Hematopoiesis Exacerbates Experimental Insulin Resistance in Aging and Obesity.
Cell reports
Fuster JJ,Zuriaga MA,Zorita V,MacLauchlan S,Polackal MN,Viana-Huete V,Ferrer-Pérez A,Matesanz N,Herrero-Cervera A,Sano S,Cooper MA,González-Navarro H,Walsh K
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Tue Oct 27 00:00:00 UTC 2020
Artificial Mini Dendritic Cells Boost T Cell-Based Immunotherapy for Ovarian Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Cheng S,Xu C,Jin Y,Li Y,Zhong C,Ma J,Yang J,Zhang N,Li Y,Wang C,Yang Z,Wang Y
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Wed Apr 01 00:00:00 UTC 2020
CNS Immune Profiling in a Dengue Virus-Infected Immunocompetent Outbred ICR Mice Strain.
Frontiers in cellular and infection microbiology
Shen TJ,Chen CL,Jhan MK,Tseng PC,Lin CF
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Thu Jun 17 00:00:00 UTC 2021
Activation of CpG-Rich Promoters Mediated by MLL Drives MOZ-Rearranged Leukemia.
Cell reports
Miyamoto R,Okuda H,Kanai A,Takahashi S,Kawamura T,Matsui H,Kitamura T,Kitabayashi I,Inaba T,Yokoyama A
17-0031-82 was used in Flow Cytometry to reveal that activation of unmethylated CpG-rich promoters mediated by MLL is the central mechanism of oncogenic self-renewal in MOZ-rearranged leukemia.
Tue Sep 29 00:00:00 UTC 2020
Bee Venom Phospholipase A2 Ameliorates Atherosclerosis by Modulating Regulatory T Cells.
Toxins
Kang GH,Lee S,Choi DB,Shin D,Kim J,Yang H,Bae H
17-0031-82 was used in Flow Cytometry to investigate bee venom phospholipase A2 (bvPLA2) as a potential therapeutic agent in atherosclerosis.
Wed Sep 23 00:00:00 UTC 2020
Tumor microenvironment remodeling by an engineered oncolytic adenovirus results in improved outcome from PD-L1 inhibition.
Oncoimmunology
Cervera-Carrascon V,Quixabeira DCA,Santos JM,Havunen R,Zafar S,Hemminki O,Heiniö C,Munaro E,Siurala M,Sorsa S,Mirtti T,Järvinen P,Mildh M,Nisen H,Rannikko A,Anttila M,Kanerva A,Hemminki A
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Fri May 22 00:00:00 UTC 2020
Critical role of WNK1 in MYC-dependent early mouse thymocyte development.
eLife
Köchl R,Vanes L,Llorian Sopena M,Chakravarty P,Hartweger H,Fountain K,White A,Cowan J,Anderson G,Tybulewicz VL
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Wed Oct 14 00:00:00 UTC 2020
Analysis of Myeloid Cells in Mouse Tissues with Flow Cytometry.
STAR protocols
Liu Z,Gu Y,Shin A,Zhang S,Ginhoux F
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Fri Jun 19 00:00:00 UTC 2020
Macrophage Sphingosine 1-Phosphate Receptor 2 Blockade Attenuates Liver Inflammation and Fibrogenesis Triggered by NLRP3 Inflammasome.
Frontiers in immunology
Hou L,Yang L,Chang N,Zhao X,Zhou X,Dong C,Liu F,Yang L,Li L
17-0031 was used in Flow cytometry/Cell sorting to show that targeting macrophage S1PR2 retarded liver inflammation and fibrogenesis via downregulating NLRP3 inflammasome.
Thu Apr 01 00:00:00 UTC 2021
Epigenetic Protection of Vertebrate Lymphoid Progenitor Cells by Dnmt1.
iScience
Iwanami N,Takeshita K,Lawir DF,Suetake I,Tajima S,Sikora K,Trancoso I,ÓMeara C,Siamishi I,Takahama Y,Furutani-Seiki M,Kondoh H,Yonezawa Y,Schorpp M,Boehm T
17-0031 was used in Flow cytometry/Cell sorting to identify new recessive dnmt1 alleles in medaka and zebrafish and, guided by the structures of mutant proteins, generated a recessive variant of mouse Dnmt1.
Fri Jul 24 00:00:00 UTC 2020
Deciphering CD4+ T cell specificity using novel MHC-TCR chimeric receptors.
Nature immunology
Kisielow J,Obermair FJ,Kopf M
17-0031 was used in Flow cytometry/Cell sorting to describe a platform for the discovery of MHC class II epitopes based on the screening of engineered reporter cells expressing novel pMHC-TCR (MCR) hybrid molecules carrying cDNA-derived peptides.
Wed May 01 00:00:00 UTC 2019
Engulfment of mast cell secretory granules on skin inflammation boosts dendritic cell migration and priming efficiency.
The Journal of allergy and clinical immunology
Dudeck J,Froebel J,Kotrba J,Lehmann CHK,Dudziak D,Speier S,Nedospasov SA,Schraven B,Dudeck A
17-0031 was used in Flow cytometry/Cell sorting to show peripheral mast cells can modify dendritic cell functionality to influence lymphoid tissue-borne adaptive immunity.
Wed May 01 00:00:00 UTC 2019
CHK1 dosage in germinal center B cells controls humoral immunity.
Cell death and differentiation
Schoeler K,Jakic B,Heppke J,Soratroi C,Aufschnaiter A,Hermann-Kleiter N,Villunger A,Labi V
17-0031-82 was used in Immunohistochemistry-immunofluorescence to show that the DNA damage response regulator Checkpoint kinase 1 (CHK1) is essential for GC B cell survival.
Sun Dec 01 00:00:00 UTC 2019
Low-Dose Apatinib Optimizes Tumor Microenvironment and Potentiates Antitumor Effect of PD-1/PD-L1 Blockade in Lung Cancer.
Cancer immunology research
Zhao S,Ren S,Jiang T,Zhu B,Li X,Zhao C,Jia Y,Shi J,Zhang L,Liu X,Qiao M,Chen X,Su C,Yu H,Zhou C,Zhang J,Camidge DR,Hirsch FR
17-0031 was used in Flow cytometry/Cell sorting to analyze the impact of apatinib, a smallmolecule VEGFR2-TKI, on the TME in murine Lewis lung carcinoma (LLC) models at different doses alone and in combination with an anti–PD-L1.
Mon Apr 01 00:00:00 UTC 2019
Cell-intrinsic depletion of Aml1-ETO-expressing pre-leukemic hematopoietic stem cells by K-Ras activating mutation.
Haematologica
Di Genua C,Norfo R,Rodriguez-Meira A,Wen WX,Drissen R,Booth CAG,Povinelli B,Repapi E,Gray N,Carrelha J,Kettyle LM,Jamieson L,Neo WH,Thongjuea S,Nerlov C,Mead AJ
17-0031 was used in Flow cytometry/Cell sorting to study the mechanism behind absence of KRAS signalling mutations in pre-malignant hematopoietic stem cell compartments.
Fri Nov 01 00:00:00 UTC 2019
1,2,3,4,6-Penta-O-galloyl-β-d-glucose modulates perivascular inflammation and prevents vascular dysfunction in angiotensin II-induced hypertension.
British journal of pharmacology
Mikolajczyk TP,Nosalski R,Skiba DS,Koziol J,Mazur M,Justo-Junior AS,Kowalczyk P,Kusmierczyk Z,Schramm-Luc A,Luc K,Maffia P,Graham D,Kiss AK,Naruszewicz M,Guzik TJ
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Sat Jun 01 00:00:00 UTC 2019
Inhibition of AIM2 inflammasome-mediated pyroptosis by Andrographolide contributes to amelioration of radiation-induced lung inflammation and fibrosis.
Cell death & disease
Gao J,Peng S,Shan X,Deng G,Shen L,Sun J,Jiang C,Yang X,Chang Z,Sun X,Feng F,Kong L,Gu Y,Guo W,Xu Q,Sun Y
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Fri Dec 20 00:00:00 UTC 2019
CD160 serves as a negative regulator of NKT cells in acute hepatic injury.
Nature communications
Kim TJ,Park G,Kim J,Lim SA,Kim J,Im K,Shin MH,Fu YX,Del Rio ML,Rodriguez-Barbosa JI,Yee C,Suh KS,Kim SJ,Ha SJ,Lee KM
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Mon Jul 22 00:00:00 UTC 2019
Sex Differences in Mouse Popliteal Lymph Nodes.
Scientific reports
Dill-Garlow R,Chen KE,Walker AM
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Wed Jan 30 00:00:00 UTC 2019
Tpl2 Protects Against Fulminant Hepatitis Through Mobilization of Myeloid-Derived Suppressor Cells.
Frontiers in immunology
Xu J,Pei S,Wang Y,Liu J,Qian Y,Huang M,Zhang Y,Xiao Y
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Wed Oct 14 00:00:00 UTC 2020
STAT1 signaling shields T cells from NK cell-mediated cytotoxicity.
Nature communications
Kang YH,Biswas A,Field M,Snapper SB
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Fri Feb 22 00:00:00 UTC 2019
Myeloid Cells Restrict MCMV and Drive Stress-Induced Extramedullary Hematopoiesis through STAT1.
Cell reports
Gawish R,Bulat T,Biaggio M,Lassnig C,Bago-Horvath Z,Macho-Maschler S,Poelzl A,Simonović N,Prchal-Murphy M,Rom R,Amenitsch L,Ferrarese L,Kornhoff J,Lederer T,Svinka J,Eferl R,Bosmann M,Kalinke U,Stoiber D,Sexl V,Krmpotić A,Jonjić S,Müller M,Strobl B
17-0031 was used in Flow cytometry/Cell sorting to provide genetic evidence that signaling through STAT1 in myeloid cells is required to restrict MCMV at early time points post-infection and to induce compensatory hematopoiesis in the spleen.
Tue Feb 26 00:00:00 UTC 2019
Orphan Nuclear Receptor NR2F6 Suppresses T Follicular Helper Cell Accumulation through Regulation of IL-21.
Cell reports
Olson WJ,Jakic B,Labi V,Schoeler K,Kind M,Klepsch V,Baier G,Hermann-Kleiter N
17-0031-82 was used in Immunohistochemistry to investigate the effects of orphan nuclear receptor NR2F6 on accumulation and survival of T follicular helper cells.
Tue Sep 10 00:00:00 UTC 2019
Maternal vaccination and protective immunity against Zika virus vertical transmission.
Nature communications
Shan C,Xie X,Luo H,Muruato AE,Liu Y,Wakamiya M,La JH,Chung JM,Weaver SC,Wang T,Shi PY
17-0031-82 was used in Flow cytometry/Cell sorting to suggest that, besides vaccinating non-pregnant individuals, 3'UTR-?10-LAV may also be considered for maternal vaccination.
Thu Dec 12 00:00:00 UTC 2019
Restricted Expression of the Thymoproteasome Is Required for Thymic Selection and Peripheral Homeostasis of CD8+ T Cells.
Cell reports
Tomaru U,Konno S,Miyajima S,Kimoto R,Onodera M,Kiuchi S,Murata S,Ishizu A,Kasahara M
17-0031 was used in Flow cytometry/Cell sorting to find that thymoproteasomes are essential for positive selection but that the subsequent change in peptide repertoire in the medulla is also crucial for thymic selection and that β5t-derived peptide must be confined to the thymus to avoid autoimmunity in peripheral tissues.
Tue Jan 15 00:00:00 UTC 2019
The T Cell Antigen Receptor α Transmembrane Domain Coordinates Triggering through Regulation of Bilayer Immersion and CD3 Subunit Associations.
Immunity
Brazin KN,Mallis RJ,Boeszoermenyi A,Feng Y,Yoshizawa A,Reche PA,Kaur P,Bi K,Hussey RE,Duke-Cohan JS,Song L,Wagner G,Arthanari H,Lang MJ,Reinherz EL
17-0031 was used in Flow cytometry/Cell sorting to suggest that mechanical forces applied during pMHC ligation initiate T cell activation via a dissociative mechanism, shifting disposition of those basic sidechains to rearrange TCR complex membrane topology and weaken TCRαβ and CD3 associations.
Tue Nov 20 00:00:00 UTC 2018
E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor.
Immunity
Li Q,Li D,Zhang X,Wan Q,Zhang W,Zheng M,Zou L,Elly C,Lee JH,Liu YC
17-0031 was used in Immunohistochemistry to indicate that the VHL-HIF-glycolysis axis is essential for the late-stage maturation and function of ILC2s via targeting IL-33-ST2 pathway.
Tue Feb 20 00:00:00 UTC 2018
Effector CD4 T cells with progenitor potential mediate chronic intestinal inflammation.
The Journal of experimental medicine
Shin B,Kress RL,Kramer PA,Darley-Usmar VM,Bellis SL,Harrington LE
17-0031 was used in Flow cytometry/Cell sorting to indicate that the chronicity of T cell-mediated inflammation is perpetuated by specific effector CD4 T cells with stem-like properties.
Mon Jul 02 00:00:00 UTC 2018
11 Beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis.
Journal of autoimmunity
Hardy RS,Fenton C,Croft AP,Naylor AJ,Begum R,Desanti G,Buckley CD,Lavery G,Cooper MS,Raza K
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Wed Aug 01 00:00:00 UTC 2018
Role of Hepatic Deposited Immunoglobulin G in the Pathogenesis of Liver Damage in Systemic Lupus Erythematosus.
Frontiers in immunology
Fang X,Zaman MH,Guo X,Ding H,Xie C,Zhang X,Deng GM
17-0031 was used in Flow cytometry/Cell sorting to investigate the role of hepatic deposited immunoglobulin G in systemic lupus erythematosus-derived liver damage.
Wed Nov 20 00:00:00 UTC 2019
Expansion of commensal fungus Wallemia mellicola in the gastrointestinal mycobiota enhances the severity of allergic airway disease in mice.
PLoS pathogens
Skalski JH,Limon JJ,Sharma P,Gargus MD,Nguyen C,Tang J,Coelho AL,Hogaboam CM,Crother TR,Underhill DM
17-0031 was used in Flow cytometry/Cell sorting to investigate the effects of the population expansion of commensal fungus Wallemia mellicola without overgrowth of the total fungal community.
Sat Sep 01 00:00:00 UTC 2018
Gli3 in fetal thymic epithelial cells promotes thymocyte positive selection and differentiation by repression of Shh.
Development (Cambridge, England)
Solanki A,Yanez DC,Ross S,Lau CI,Papaioannou E,Li J,Saldaña JI,Crompton T
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Wed Jan 31 00:00:00 UTC 2018
On-target and direct modulation of alloreactive T cells by a nanoparticle carrying MHC alloantigen, regulatory molecules and CD47 in a murine model of alloskin transplantation.
Drug delivery
Shahzad KA,Wan X,Zhang L,Pei W,Zhang A,Younis M,Wang W,Shen C
17-0031 was used in Flow cytometry/Cell sorting to examine the direct and antigen-specific modulation on T cells by nanoparticles and combined use of multiple regulatory molecules.
Thu Nov 01 00:00:00 UTC 2018
Granulocyte-macrophage colony-stimulating factor neuroprotective activities in Alzheimer's disease mice.
Journal of neuroimmunology
Kiyota T,Machhi J,Lu Y,Dyavarshetty B,Nemati M,Yokoyama I,Mosley RL,Gendelman HE
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Fri Jun 15 00:00:00 UTC 2018
Protective function of Bu Shen Huo Xue formula on the immunity of B6AF1 mice with experimental autoimmune premature ovarian failure.
Experimental and therapeutic medicine
Wang P,Lu Y,Chen S,Chen Y,Hu C,Zuo Y
17-0031-82 was used in Flow Cytometry to evaluate the immunoprotective effects of Bu Shen Huo Xue formula on premature ovarian failure and the underlying mechanisms.
Sun Apr 01 00:00:00 UTC 2018
Sipa1 deficiency unleashes a host-immune mechanism eradicating chronic myelogenous leukemia-initiating cells.
Nature communications
Xu Y,Ikeda S,Sumida K,Yamamoto R,Tanaka H,Minato N
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Fri Mar 02 00:00:00 UTC 2018
A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment.
eLife
Ng KK,Yui MA,Mehta A,Siu S,Irwin B,Pease S,Hirose S,Elowitz MB,Rothenberg EV,Kueh HY
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Tue Nov 20 00:00:00 UTC 2018
ADAMTS1 protease is required for a balanced immune cell repertoire and tumour inflammatory response.
Scientific reports
Rodríguez-Baena FJ,Redondo-García S,Peris-Torres C,Martino-Echarri E,Fernández-Rodríguez R,Plaza-Calonge MDC,Anderson P,Rodríguez-Manzaneque JC
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Thu Aug 30 00:00:00 UTC 2018
Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias.
Nature communications
Chaudhury S,O'Connor C,Cañete A,Bittencourt-Silvestre J,Sarrou E,Prendergast Á,Choi J,Johnston P,Wells CA,Gibson B,Keeshan K
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Tue Dec 11 00:00:00 UTC 2018
Retinoid-Sensitive Epigenetic Regulation of the Hoxb Cluster Maintains Normal Hematopoiesis and Inhibits Leukemogenesis.
Cell stem cell
Qian P,De Kumar B,He XC,Nolte C,Gogol M,Ahn Y,Chen S,Li Z,Xu H,Perry JM,Hu D,Tao F,Zhao M,Han Y,Hall K,Peak A,Paulson A,Zhao C,Venkatraman A,Box A,Perera A,Haug JS,Parmely T,Li H,Krumlauf R,Li L
17-0031 was used in Flow cytometry/Cell sorting to demonstrate roles for retinoid signaling and the DERARE in maintaining HSCs and preventing leukemogenesis by coordinate regulation of Hoxb genes.
Thu May 03 00:00:00 UTC 2018
Group 2 Innate Lymphoid Cells Attenuate Inflammatory Arthritis and Protect from Bone Destruction in Mice.
Cell reports
Omata Y,Frech M,Primbs T,Lucas S,Andreev D,Scholtysek C,Sarter K,Kindermann M,Yeremenko N,Baeten DL,Andreas N,Kamradt T,Bozec A,Ramming A,Krönke G,Wirtz S,Schett G,Zaiss MM
17-0031 was used in Immunohistochemistry to elucidate the role of group 2 innate lymphoid cells in arthritis.
Tue Jul 03 00:00:00 UTC 2018
Hematopoietic stem cells can differentiate into restricted myeloid progenitors before cell division in mice.
Nature communications
Grinenko T,Eugster A,Thielecke L,Ramasz B,Krüger A,Dietz S,Glauche I,Gerbaulet A,von Bonin M,Basak O,Clevers H,Chavakis T,Wielockx B
17-0031 was used in Flow cytometry/Cell sorting to study the mechanisms that control fate decision in adult haematopoietic stem cells.s.
Tue May 15 00:00:00 UTC 2018
Nuclear receptor NR2F6 inhibition potentiates responses to PD-L1/PD-1 cancer immune checkpoint blockade.
Nature communications
Klepsch V,Hermann-Kleiter N,Do-Dinh P,Jakic B,Offermann A,Efremova M,Sopper S,Rieder D,Krogsdam A,Gamerith G,Perner S,Tzankov A,Trajanoski Z,Wolf D,Baier G
17-0031 was used in Flow cytometry/Cell sorting to define NR2F6 as an intracellular immune checkpoint with potential as a therapeutic target in cancer treatment.
Wed Apr 18 00:00:00 UTC 2018
Indoleamine 2 3-dioxygenase knockout limits angiotensin II-induced aneurysm in low density lipoprotein receptor-deficient mice fed with high fat diet.
PloS one
Metghalchi S,Vandestienne M,Haddad Y,Esposito B,Dairou J,Tedgui A,Mallat Z,Potteaux S,Taleb S
17-0031 was used in Flow cytometry/Cell sorting to show that the knockout of IDO prevented VSMC apoptosis in AngII -treated Ldlr-/- mice fed with HFD, suggesting a detrimental role of IDO in AAA formation and thus would be an important target for the treatment of aneurysm.
Fri Jun 22 00:00:00 UTC 2018
Transcription factors early growth response gene (Egr) 2 and 3 control inflammatory responses of tolerant T cells.
Immunity, inflammation and disease
Omodho B,Miao T,Symonds ALJ,Singh R,Li S,Wang P
Fri Jun 01 00:00:00 UTC 2018
CD9+ Regulatory B Cells Induce T Cell Apoptosis via IL-10 and Are Reduced in Severe Asthmatic Patients.
Frontiers in immunology
Brosseau C,Durand M,Colas L,Durand E,Foureau A,Cheminant MA,Bouchaud G,Castan L,Klein M,Magnan A,Brouard S
17-0031 was used in Flow cytometry/Cell sorting to study CD9+ B cell defects in causing lack of regulation of inflammation in patients with severe asthma.
Fri Oct 25 00:00:00 UTC 2019
Myc Cooperates with Ras by Programming Inflammation and Immune Suppression.
Cell
Kortlever RM,Sodir NM,Wilson CH,Burkhart DL,Pellegrinet L,Brown Swigart L,Littlewood TD,Evan GI
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Thu Nov 30 00:00:00 UTC 2017
A Viral Immunoevasin Controls Innate Immunity by Targeting the Prototypical Natural Killer Cell Receptor Family.
Cell
Aguilar OA,Berry R,Rahim MMA,Reichel JJ,Popović B,Tanaka M,Fu Z,Balaji GR,Lau TNH,Tu MM,Kirkham CL,Mahmoud AB,Mesci A,Krmpotić A,Allan DSJ,Makrigiannis AP,Jonjić S,Rossjohn J,Carlyle JR
17-0031 was used in Flow cytometry/Cell sorting to identify a viral ligand for the inhibitory and activating NKR-P1 receptors.
Thu Mar 23 00:00:00 UTC 2017
Interleukin-33-Activated Islet-Resident Innate Lymphoid Cells Promote Insulin Secretion through Myeloid Cell Retinoic Acid Production.
Immunity
Dalmas E,Lehmann FM,Dror E,Wueest S,Thienel C,Borsigova M,Stawiski M,Traunecker E,Lucchini FC,Dapito DH,Kallert SM,Guigas B,Pattou F,Kerr-Conte J,Maechler P,Girard JP,Konrad D,Wolfrum C,Böni-Schnetzler M,Finke D,Donath MY
17-0031 was used in Flow cytometry/Cell sorting to provide evidence that an immunometabolic crosstalk between islet-derived IL-33, ILC2s, and myeloid cells fosters insulin secretion.
Tue Nov 21 00:00:00 UTC 2017
Autoreactive T Cells and Chronic Fungal Infection Drive Esophageal Carcinogenesis.
Cell host & microbe
Zhu F,Willette-Brown J,Song NY,Lomada D,Song Y,Xue L,Gray Z,Zhao Z,Davis SR,Sun Z,Zhang P,Wu X,Zhan Q,Richie ER,Hu Y
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Wed Apr 12 00:00:00 UTC 2017
Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia.
Nature immunology
Fang J,Bolanos LC,Choi K,Liu X,Christie S,Akunuru S,Kumar R,Wang D,Chen X,Greis KD,Stoilov P,Filippi MD,Maciejewski JP,Garcia-Manero G,Weirauch MT,Salomonis N,Geiger H,Zheng Y,Starczynowski DT
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Wed Feb 01 00:00:00 UTC 2017
A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.
The Journal of clinical investigation
Berlato C,Khan MN,Schioppa T,Thompson R,Maniati E,Montfort A,Jangani M,Canosa M,Kulbe H,Hagemann UB,Duncan AR,Fletcher L,Wilkinson RW,Powles T,Quezada SA,Balkwill FR
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Wed Mar 01 00:00:00 UTC 2017
PTEN drives Th17 cell differentiation by preventing IL-2 production.
The Journal of experimental medicine
Kim HS,Jang SW,Lee W,Kim K,Sohn H,Hwang SS,Lee GR
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Mon Nov 06 00:00:00 UTC 2017
Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation.
The Journal of experimental medicine
Miao T,Symonds ALJ,Singh R,Symonds JD,Ogbe A,Omodho B,Zhu B,Li S,Wang P
17-0031 was used in Flow cytometry/Cell sorting to define a fundamental function of Egr2 and Egr3, operating as a checkpoint controlling the transition between clonal expansion and differentiation of effector T cells.
Mon Jun 05 00:00:00 UTC 2017
RIG-I antiviral signaling drives interleukin-23 production and psoriasis-like skin disease.
EMBO molecular medicine
Zhu H,Lou F,Yin Q,Gao Y,Sun Y,Bai J,Xu Z,Liu Z,Cai W,Ke F,Zhang L,Zhou H,Wang H,Wang G,Chen X,Zhang H,Wang Z,Ginhoux F,Lu C,Su B,Wang H
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Mon May 01 00:00:00 UTC 2017
RIG-I antiviral signaling drives interleukin-23 production and psoriasis-like skin disease.
EMBO molecular medicine
Zhu H,Lou F,Yin Q,Gao Y,Sun Y,Bai J,Xu Z,Liu Z,Cai W,Ke F,Zhang L,Zhou H,Wang H,Wang G,Chen X,Zhang H,Wang Z,Ginhoux F,Lu C,Su B,Wang H
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Mon May 01 00:00:00 UTC 2017
Profiling MHC II immunopeptidome of blood-stage malaria reveals that cDC1 control the functionality of parasite-specific CD4 T cells.
EMBO molecular medicine
Draheim M,Wlodarczyk MF,Crozat K,Saliou JM,Alayi TD,Tomavo S,Hassan A,Salvioni A,Demarta-Gatsi C,Sidney J,Sette A,Dalod M,Berry A,Silvie O,Blanchard N
17-0031 was used in Flow cytometry/Cell sorting to establish the immunodominance hierarchy of 14 MHC II ligands derived from conserved parasite proteins.
Wed Nov 01 00:00:00 UTC 2017
PI3Kγ Activates Integrin α4 and Promotes Immune Suppressive Myeloid Cell Polarization during Tumor Progression.
Cancer immunology research
Foubert P,Kaneda MM,Varner JA
17-0031 was used in Flow cytometry/Cell sorting to highlight PI3Kγ and integrin α4 as targets for the design of cancer therapeutics.
Wed Nov 01 00:00:00 UTC 2017
An Antigen-Presenting and Apoptosis-Inducing Polymer Microparticle Prolongs Alloskin Graft Survival by Selectively and Markedly Depleting Alloreactive CD8+ T Cells.
Frontiers in immunology
Wang W,Shahzad KA,Li M,Zhang A,Zhang L,Xu T,Wan X,Shen C
17-0031 was used in Flow cytometry/Cell sorting to document the high potential of PLGA MP-based KaAPCs as a novel antigen-specific immunotherapy for allograft rejection and autoimmune disorder.
Wed Nov 20 00:00:00 UTC 2019
MyD88 signaling in dendritic cells and the intestinal epithelium controls immunity against intestinal infection with C. rodentium.
PLoS pathogens
Friedrich C,Mamareli P,Thiemann S,Kruse F,Wang Z,Holzmann B,Strowig T,Sparwasser T,Lochner M
17-0031 was used in Flow cytometry/Cell sorting to suggest that MyD88 signaling in DC and IEC is both essential and sufficient to induce a full spectrum of host responses upon intestinal infection with C. rodentium.
Mon May 01 00:00:00 UTC 2017
Hydrogen-Rich Water Ameliorates Total Body Irradiation-Induced Hematopoietic Stem Cell Injury by Reducing Hydroxyl Radical.
Oxidative medicine and cellular longevity
Zhang J,Xue X,Han X,Li Y,Lu L,Li D,Fan S
Thu Mar 16 00:00:00 UTC 2017
Betulin from Hedyotis hedyotidea ameliorates concanavalin A-induced and T cell-mediated autoimmune hepatitis in mice.
Acta pharmacologica Sinica
Zhou YQ,Weng XF,Dou R,Tan XS,Zhang TT,Fang JB,Wu XW
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Wed Feb 01 00:00:00 UTC 2017
T cell-dependent antigen adjuvanted with DOTAP-CpG-B but not DOTAP-CpG-A induces robust germinal center responses and high affinity antibodies in mice.
European journal of immunology
Akkaya M,Akkaya B,Sheehan PW,Miozzo P,Pena M,Qi CF,Manzella-Lapeira J,Bolland S,Pierce SK
17-0031 was used in Flow cytometry/Cell sorting to compare the outcome of immunisation with the T-cell dependent antigen, NP-conjugated to chicken gamma globulin adjuvanted, with CpG-A or CpG-B, alone or conjugated with the cationic lipid carrier, DOTAP.
Wed Nov 01 00:00:00 UTC 2017
Cytochrome P450 26A1 modulates natural killer cells in mouse early pregnancy.
Journal of cellular and molecular medicine
Meng CY,Li ZY,Fang WN,Song ZH,Yang DD,Li DD,Yang Y,Peng JP
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Sat Apr 01 00:00:00 UTC 2017
Isolation of cell type-specific apoptotic bodies by fluorescence-activated cell sorting.
Scientific reports
Atkin-Smith GK,Paone S,Zanker DJ,Duan M,Phan TK,Chen W,Hulett MD,Poon IK
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Fri Jan 06 00:00:00 UTC 2017
The major targets of acute norovirus infection are immune cells in the gut-associated lymphoid tissue.
Nature microbiology
Grau KR,Roth AN,Zhu S,Hernandez A,Colliou N,DiVita BB,Philip DT,Riffe C,Giasson B,Wallet SM,Mohamadzadeh M,Karst SM
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Fri Dec 01 00:00:00 UTC 2017
Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity.
Nature communications
Zamarin D,Holmgaard RB,Ricca J,Plitt T,Palese P,Sharma P,Merghoub T,Wolchok JD,Allison JP
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Mon Feb 13 00:00:00 UTC 2017
Lithocholic acid controls adaptive immune responses by inhibition of Th1 activation through the Vitamin D receptor.
PloS one
Pols TWH,Puchner T,Korkmaz HI,Vos M,Soeters MR,de Vries CJM
17-0031 was used in Flow cytometry/Cell sorting to study the mechanism by which lithocholic acid controls adaptive immunity.
Mon Sep 11 00:00:00 UTC 2017
Smac mimetics and oncolytic viruses synergize in driving anticancer T-cell responses through complementary mechanisms.
Nature communications
Kim DS,Dastidar H,Zhang C,Zemp FJ,Lau K,Ernst M,Rakic A,Sikdar S,Rajwani J,Naumenko V,Balce DR,Ewanchuk BW,Tailor P,Yates RM,Jenne C,Gafuik C,Mahoney DJ
17-0031 was used in Flow cytometry/Cell sorting to show that SMC and OV therapies combination also synergize in vivo by promoting anticancer immunity through an increase in CD8(+) T-cell response.
Thu Aug 24 00:00:00 UTC 2017
Heavy Chain-Hyaluronan/Pentraxin 3 from Amniotic Membrane Suppresses Inflammation and Scarring in Murine Lacrimal Gland and Conjunctiva of Chronic Graft-versus-Host Disease.
Scientific reports
Ogawa Y,He H,Mukai S,Imada T,Nakamura S,Su CW,Mahabole M,Tseng SC,Tsubota K
17-0031 was used in Immunohistochemistry to help prove the concept that subcutaneous and subconjunctival injection of HC-HA/PTX3 is a novel approach to prevent dry eye disease caused by cGVHD.
Mon Feb 06 00:00:00 UTC 2017
Rutin-Enriched Extract from Coriandrum sativum L. Ameliorates Ionizing Radiation-Induced Hematopoietic Injury.
International journal of molecular sciences
Han X,Xue X,Zhao Y,Li Y,Liu W,Zhang J,Fan S
17-0031 was used in Flow cytometry/Cell sorting to demonstrate that rutin-enriched coriander extract is able to ameliorate ionising radiation-induced haematopoietic injury partly by reducing ionising radiation-induced oxidative stress.
Sat Apr 29 00:00:00 UTC 2017
Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome.
Cell
Chudnovskiy A,Mortha A,Kana V,Kennard A,Ramirez JD,Rahman A,Remark R,Mogno I,Ng R,Gnjatic S,Amir ED,Solovyov A,Greenbaum B,Clemente J,Faith J,Belkaid Y,Grigg ME,Merad M
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Thu Oct 06 00:00:00 UTC 2016
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.
Cell
Damgaard RB,Walker JA,Marco-Casanova P,Morgan NV,Titheradge HL,Elliott PR,McHale D,Maher ER,McKenzie ANJ,Komander D
17-0031 was used in Flow cytometry/Cell sorting to study how OTULIN may be critical in restraining life-threatening spontaneous inflammation and maintaining immune homeostasis.
Thu Aug 25 00:00:00 UTC 2016
Antitumor adaptive immunity remains intact following inhibition of autophagy and antimalarial treatment.
The Journal of clinical investigation
Starobinets H,Ye J,Broz M,Barry K,Goldsmith J,Marsh T,Rostker F,Krummel M,Debnath J
17-0031 was used in Flow cytometry/Cell sorting to evaluate how autophagy inhibition impacts the antitumor immune response in immune-competent mouse models of melanoma and mammary cancer.
Thu Dec 01 00:00:00 UTC 2016
Autophagy deficiency in myeloid cells increases susceptibility to obesity-induced diabetes and experimental colitis.
Autophagy
Lee HY,Kim J,Quan W,Lee JC,Kim MS,Kim SH,Bae JW,Hur KY,Lee MS
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Tue Aug 02 00:00:00 UTC 2016
Peptidoglycan-linked protein A promotes T cell-dependent antibody expansion during Staphylococcus aureus infection.
Proceedings of the National Academy of Sciences of the United States of America
Kim HK,Falugi F,Missiakas DM,Schneewind O
17-0031 was used in Flow cytometry/Cell sorting to suggest that staphylococcal protein A cross-linking of VH3 idiotype BCRs and activation via attached peptidoglycan are determinants of staphylococcal escape from adaptive immune responses.
Tue May 17 00:00:00 UTC 2016
Lung epithelium and myeloid cells cooperate to clear acute pneumococcal infection.
Mucosal immunology
Dudek M,Puttur F,Arnold-Schrauf C,Kühl AA,Holzmann B,Henriques-Normark B,Berod L,Sparwasser T
17-0031 was used in Flow cytometry/Cell sorting to investigate the extent to which MyD88 signaling is required to control S. pneumoniae infection, showing that lung epithelium and myeloid cells cooperate to clear infection.
Thu Sep 01 00:00:00 UTC 2016
Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency.
Journal of immunology (Baltimore, Md. : 1950)
Menendez CM,Jinkins JK,Carr DJ
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Mon Aug 15 00:00:00 UTC 2016
Treatment with Interleukin-7 Restores Host Defense against Pneumocystis in CD4+ T-Lymphocyte-Depleted Mice.
Infection and immunity
Ruan S,Samuelson DR,Assouline B,Morre M,Shellito JE
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Fri Jan 01 00:00:00 UTC 2016
Protectin D1 reduces concanavalin A-induced liver injury by inhibiting NF-κB-mediated CX3CL1/CX3CR1 axis and NLR family, pyrin domain containing 3 inflammasome activation.
Molecular medicine reports
Ren J,Meng S,Yan B,Yu J,Liu J
17-0031 was used in Flow cytometry/Cell sorting to show that protectin D1 reduces concanavalin A-induced liver injury.
Fri Apr 01 00:00:00 UTC 2016
A New Model to Study the Role of Arachidonic Acid in Colon Cancer Pathophysiology.
Cancer prevention research (Philadelphia, Pa.)
Fan YY,Callaway E,M Monk J,S Goldsby J,Yang P,Vincent L,S Chapkin R
17-0031 was used in Flow cytometry/Cell sorting to develop a novel model for the study of arachidonic acid in colon cancer pathophysiology.
Thu Sep 01 00:00:00 UTC 2016
Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency.
Stem cell reports
Mucci A,Kunkiel J,Suzuki T,Brennig S,Glage S,Kühnel MP,Ackermann M,Happle C,Kuhn A,Schambach A,Trapnell BC,Hansen G,Moritz T,Lachmann N
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Tue Aug 09 00:00:00 UTC 2016
Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis.
Nature communications
Ruhland MK,Loza AJ,Capietto AH,Luo X,Knolhoff BL,Flanagan KC,Belt BA,Alspach E,Leahy K,Luo J,Schaffer A,Edwards JR,Longmore G,Faccio R,DeNardo DG,Stewart SA
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Wed Jun 08 00:00:00 UTC 2016
The dual role of NK cells in antitumor reactions triggered by ionizing radiation in combination with hyperthermia.
Oncoimmunology
Finkel P,Frey B,Mayer F,Bösl K,Werthmöller N,Mackensen A,Gaipl US,Ullrich E
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Wed Jun 01 00:00:00 UTC 2016
The ER membrane-anchored ubiquitin ligase Hrd1 is a positive regulator of T-cell immunity.
Nature communications
Xu Y,Zhao F,Qiu Q,Chen K,Wei J,Kong Q,Gao B,Melo-Cardenas J,Zhang B,Zhang J,Song J,Zhang DD,Zhang J,Fan Y,Li H,Fang D
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Fri Jul 15 00:00:00 UTC 2016
Irradiation of necrotic cancer cells, employed for pulsing dendritic cells (DCs), potentiates DC vaccine-induced antitumor immunity against high-grade glioma.
Oncoimmunology
Vandenberk L,Garg AD,Verschuere T,Koks C,Belmans J,Beullens M,Agostinis P,De Vleeschouwer S,Van Gool SW
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Mon Feb 01 00:00:00 UTC 2016
Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy.
Nature communications
Chen Q,Xu L,Liang C,Wang C,Peng R,Liu Z
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Fri Oct 21 00:00:00 UTC 2016
A biodegradable killer microparticle to selectively deplete antigen-specific T cells in vitro and in vivo.
Oncotarget
Wang W,Fang K,Li MC,Chang D,Shahzad KA,Xu T,Zhang L,Gu N,Shen CL
17-0031 was used in Flow cytometry/Cell sorting to investigate whether poly(lactic-co-glycolic acid) polyesters can covalently load antigen and mAb to generate killer microparticles able to deplete antigen-specific T cells.
Tue Mar 15 00:00:00 UTC 2016
Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke.
Nature communications
Szalay G,Martinecz B,Lénárt N,Környei Z,Orsolits B,Judák L,Császár E,Fekete R,West BL,Katona G,Rózsa B,Dénes Á
17-0031 was used in Flow cytometry/Cell sorting to investigate the influence of microglia on neuronal activity and survival in the injured brain in vivo.
Tue May 03 00:00:00 UTC 2016
Adjuvanted multi-epitope vaccines protect HLA-A*11:01 transgenic mice against Toxoplasma gondii.
JCI insight
El Bissati K,Chentoufi AA,Krishack PA,Zhou Y,Woods S,Dubey JP,Vang L,Lykins J,Broderick KE,Mui E,Suzuki Y,Sa Q,Bi S,Cardona N,Verma SK,Fraczek L,Reardon CA,Sidney J,Alexander J,Sette A,Vedvick T,Fox C,Guderian JA,Reed S,Roberts CW,McLeod R
17-0031 was used in Flow cytometry/Cell sorting to develop multi-epitope DNA or protein vaccines with TLR4 ligand emulsion adjuvant to protect against Toxoplasma gondii.
Thu Sep 22 00:00:00 UTC 2016
Reprogramming mouse fibroblasts into engraftable myeloerythroid and lymphoid progenitors.
Nature communications
Cheng H,Ang HY,A El Farran C,Li P,Fang HT,Liu TM,Kong SL,Chin ML,Ling WY,Lim EK,Li H,Huber T,Loh KM,Loh YH,Lim B
17-0031 was used in Flow cytometry/Cell sorting to demonstrate how it is possible to reprogram mouse embryonic fibroblasts into engraftable blood progenitors.
Mon Nov 21 00:00:00 UTC 2016
Antigen presenting cell abnormalities in the Cln3(-/-) mouse model of juvenile neuronal ceroid lipofuscinosis.
Biochimica et biophysica acta
Hersrud SL,Kovács AD,Pearce DA
17-0031 was used in Flow cytometry/Cell sorting to show that CLN3 deficiency alters antigen presenting cells, which can contribute to the autoimmune response in juvenile neuronal ceroid lipofuscinosis.
Fri Jul 01 00:00:00 UTC 2016
Apoptotic cells trigger a membrane-initiated pathway to increase ABCA1.
The Journal of clinical investigation
Fond AM,Lee CS,Schulman IG,Kiss RS,Ravichandran KS
17-0031 was used in Flow cytometry/Cell sorting to identify a membrane-initiated pathway that is triggered by apoptotic cells to enhance ABCA1 within engulfing phagocytes.
Wed Jul 01 00:00:00 UTC 2015
Flow-induced protein kinase A-CREB pathway acts via BMP signaling to promote HSC emergence.
The Journal of experimental medicine
Kim PG,Nakano H,Das PP,Chen MJ,Rowe RG,Chou SS,Ross SJ,Sakamoto KM,Zon LI,Schlaeger TM,Orkin SH,Nakano A,Daley GQ
17-0031 was used in Flow cytometry/Cell sorting to identify a novel signalling pathway that regulates haematopoietic stem cell emergence in the aorta-gonad-mesonephros.
Mon May 04 00:00:00 UTC 2015
Blocking stroke-induced immunodeficiency increases CNS antigen-specific autoreactivity but does not worsen functional outcome after experimental stroke.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Römer C,Engel O,Winek K,Hochmeister S,Zhang T,Royl G,Klehmet J,Dirnagl U,Meisel C,Meisel A
Wed May 20 00:00:00 UTC 2015
A tumor lysate is an effective vaccine antigen for the stimulation of CD4(+) T-cell function and subsequent induction of antitumor immunity mediated by CD8(+) T cells.
Cancer biology & therapy
Kawahara M,Takaku H
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Mon Sep 12 00:00:00 UTC 2016
Modulatory Effects of Astragalus Polysaccharides on T-Cell Polarization in Mice with Polymicrobial Sepsis.
Mediators of inflammation
Hou YC,Wu JM,Wang MY,Wu MH,Chen KY,Yeh SL,Lin MT
17-0031 was used in Flow cytometry/Cell sorting to demonstrate that appropriate dosage of APS reduces Treg populations and elicits a more balanced Th1/Th2 response to attenuate sepsis-induced immunosuppression.
Tue Sep 20 00:00:00 UTC 2016
Adjuvants may reduce in vivo transfection levels for DNA vaccination in mice leading to reduced antigen-specific CD8+ T cell responses.
Human vaccines & immunotherapeutics
Rose AH,Hoffmann FW,Hara JH,Urschitz J,Moisyadi S,Hoffmann PR,Bertino P
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Mon May 16 00:00:00 UTC 2016
Control of the Survival and Growth of Human Glioblastoma Grafted Into the Spinal Cord of Mice by Taking Advantage of Immunorejection.
Cell transplantation
Itakura G,Kobayashi Y,Nishimura S,Iwai H,Takano M,Iwanami A,Toyama Y,Okano H,Nakamura M
17-0031 was used in Flow cytometry/Cell sorting to establish a glioblastoma multiforme xenograft model mouse.
Mon Apr 11 00:00:00 UTC 2016
The Nuclear Orphan Receptor NR2F6 Is a Central Checkpoint for Cancer Immune Surveillance.
Cell reports
Hermann-Kleiter N,Klepsch V,Wallner S,Siegmund K,Klepsch S,Tuzlak S,Villunger A,Kaminski S,Pfeifhofer-Obermair C,Gruber T,Wolf D,Baier G
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Tue Sep 29 00:00:00 UTC 2015
Metronomic cyclophosphamide eradicates large implanted GL261 gliomas by activating antitumor Cd8+ T-cell responses and immune memory.
Oncoimmunology
Wu J,Waxman DJ
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Wed Apr 01 00:00:00 UTC 2015
Interleukin-25 Mediates Transcriptional Control of PD-L1 via STAT3 in Multipotent Human Mesenchymal Stromal Cells (hMSCs) to Suppress Th17 Responses.
Stem cell reports
Wang WB,Yen ML,Liu KJ,Hsu PJ,Lin MH,Chen PM,Sudhir PR,Chen CH,Chen CH,Sytwu HK,Yen BL
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Tue Sep 08 00:00:00 UTC 2015
A Multiple Antigenic Peptide Mimicking Peptidoglycan Induced T Cell Responses to Protect Mice from Systemic Infection with Staphylococcus aureus.
PloS one
Wang XY,Huang ZX,Chen YG,Lu X,Zhu P,Wen K,Fu N,Liu BY
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Tue May 24 00:00:00 UTC 2016
Antibiotics in neonatal life increase murine susceptibility to experimental psoriasis.
Nature communications
Zanvit P,Konkel JE,Jiao X,Kasagi S,Zhang D,Wu R,Chia C,Ajami NJ,Smith DP,Petrosino JF,Abbatiello B,Nakatsukasa H,Chen Q,Belkaid Y,Chen ZJ,Chen W
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Tue Sep 29 00:00:00 UTC 2015
Overexpression of IL-15 promotes tumor destruction via NK1.1+ cells in a spontaneous breast cancer model.
BMC cancer
Gillgrass AE,Chew MV,Krneta T,Ashkar AA
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Thu Apr 16 00:00:00 UTC 2015
PARP inhibition by olaparib or gene knockout blocks asthma-like manifestation in mice by modulating CD4(+) T cell function.
Journal of translational medicine
Ghonim MA,Pyakurel K,Ibba SV,Al-Khami AA,Wang J,Rodriguez P,Rady HF,El-Bahrawy AH,Lammi MR,Mansy MS,Al-Ghareeb K,Ramsay A,Ochoa A,Naura AS,Boulares AH
17-0031 was used in Flow cytometry/Cell sorting to examine the efficacy of olaparib in blocking established allergic airway inflammation and hyperresponsiveness similar to those observed in human asthma in animal models of the disease.
Tue Jul 14 00:00:00 UTC 2015
Immunostimulatory Effects Triggered by Enterococcus faecalis CECT7121 Probiotic Strain Involve Activation of Dendritic Cells and Interferon-Gamma Production.
PloS one
Molina MA,Díaz AM,Hesse C,Ginter W,Gentilini MV,Nuñez GG,Canellada AM,Sparwasser T,Berod L,Castro MS,Manghi MA
17-0031 was used in Flow cytometry/Cell sorting to elucidate the influence of E. faecalis CECT7121 on dendritic cells and the outcome of the immune responses.
Tue Apr 19 00:00:00 UTC 2016
Controlling immune rejection is a fail-safe system against potential tumorigenicity after human iPSC-derived neural stem cell transplantation.
PloS one
Itakura G,Kobayashi Y,Nishimura S,Iwai H,Takano M,Iwanami A,Toyama Y,Okano H,Nakamura M
17-0031 was used in Flow cytometry/Cell sorting to determine the feasibility of ablation of the tumors formed after hiPSC-NS/PC transplantation through immunoregulation.
Tue Dec 01 00:00:00 UTC 2015
Superantigens Modulate Bacterial Density during Staphylococcus aureus Nasal Colonization.
Toxins
Xu SX,Kasper KJ,Zeppa JJ,McCormick JK
17-0031 was used in Flow cytometry/Cell sorting to investigate how staphylococcal SAgs may be involved in regulating bacterial densities during nasal colonisation.
Fri May 22 00:00:00 UTC 2015
Sunitinib depletes myeloid-derived suppressor cells and synergizes with a cancer vaccine to enhance antigen-specific immune responses and tumor eradication.
Oncoimmunology
Draghiciu O,Nijman HW,Hoogeboom BN,Meijerhof T,Daemen T
17-0031 was used in Flow cytometry/Cell sorting to demonstrate that sunitinib can create a favourable microenvironment depleted of MDSCs, and act synergistically with a cancer vaccine, resulting in enhanced levels of active tumor-antigen specific CTLs.
Sun Mar 01 00:00:00 UTC 2015
Rhinovirus-induced IL-25 in asthma exacerbation drives type 2 immunity and allergic pulmonary inflammation.
Science translational medicine
Beale J,Jayaraman A,Jackson DJ,Macintyre JDR,Edwards MR,Walton RP,Zhu J,Man Ching Y,Shamji B,Edwards M,Westwick J,Cousins DJ,Yi Hwang Y,McKenzie A,Johnston SL,Bartlett NW
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Wed Oct 01 00:00:00 UTC 2014
Bacterial superantigens promote acute nasopharyngeal infection by Streptococcus pyogenes in a human MHC Class II-dependent manner.
PLoS pathogens
Kasper KJ,Zeppa JJ,Wakabayashi AT,Xu SX,Mazzuca DM,Welch I,Baroja ML,Kotb M,Cairns E,Cleary PP,Haeryfar SM,McCormick JK
17-0031 was used in Flow cytometry/Cell sorting to study how secreted superantigens contribute to the fitness and evolution of S. pyogenes.
Thu May 01 00:00:00 UTC 2014
Dietary gluten increases natural killer cell cytotoxicity and cytokine secretion.
European journal of immunology
Larsen J,Dall M,Antvorskov JC,Weile C,Engkilde K,Josefsen K,Buschard K
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Wed Oct 01 00:00:00 UTC 2014
CD41 is a reliable identification and activation marker for murine basophils in the steady state and during helminth and malarial infections.
European journal of immunology
Bakocevic N,Claser C,Yoshikawa S,Jones LA,Chew S,Goh CC,Malleret B,Larbi A,Ginhoux F,de Lafaille MC,Karasuyama H,Renia L,Ng LG
17-0031 was used in Flow cytometry/Cell sorting to study the CD41 expression within basophils from the blood during both steady state and malarial inections within mice.
Sun Jun 01 00:00:00 UTC 2014
Siglec-G deficiency leads to more severe collagen-induced arthritis and earlier onset of lupus-like symptoms in MRL/lpr mice.
Journal of immunology (Baltimore, Md. : 1950)
Bökers S,Urbat A,Daniel C,Amann K,Smith KG,Espéli M,Nitschke L
17-0031 was used in Flow cytometry/Cell sorting to study how loss of the inhibitory receptor Siglec-G led to a moderate exacerbation of disease severity and early onset in both collagen-induced arthritis and spontaneous lupus nephritis.
Tue Apr 01 00:00:00 UTC 2014
Functional effects of TGF-β1 on mesenchymal stem cell mobilization in cockroach allergen-induced asthma.
Journal of immunology (Baltimore, Md. : 1950)
Gao P,Zhou Y,Xian L,Li C,Xu T,Plunkett B,Huang SK,Wan M,Cao X
17-0031 was used in Flow cytometry/Cell sorting to investigate the role of TGF-β1 in mesenchymal stem cell migration in allergic asthma.
Thu May 15 00:00:00 UTC 2014
T Cell factor 1 represses CD8+ effector T cell formation and function.
Journal of immunology (Baltimore, Md. : 1950)
Tiemessen MM,Baert MR,Kok L,van Eggermond MC,van den Elsen PJ,Arens R,Staal FJ
17-0031 was used in Flow cytometry/Cell sorting to explore the role of the Wnt-responsive transcription factor T cell factor 1 in the initial phases of CD8(+) T effector cell formation.
Mon Dec 01 00:00:00 UTC 2014
A novel pro-angiogenic function for interferon-γ-secreting natural killer cells.
Investigative ophthalmology & visual science
Lee H,Schlereth SL,Park EY,Emami-Naeini P,Chauhan SK,Dana R
17-0031 was used in Flow cytometry/Cell sorting to explore the function of natural killer cells in inflammatory angiogenesis in mice.
Fri May 02 00:00:00 UTC 2014
Superantigens subvert the neutrophil response to promote abscess formation and enhance Staphylococcus aureus survival in vivo.
Infection and immunity
Xu SX,Gilmore KJ,Szabo PA,Zeppa JJ,Baroja ML,Haeryfar SM,McCormick JK
17-0031 was used in Flow cytometry/Cell sorting to study host immune responses to superantigen toxins released by S. aureus.
Mon Sep 01 00:00:00 UTC 2014
Role of IL-17 and TGF-β in peritoneal adhesion formation after surgical trauma.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
Wang G,Wu K,Li W,Zhao E,Shi L,Wang J,Shuai X,Cai K,Lu X,Tao K,Wang G
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Tue Jun 30 00:00:00 UTC 2015
Administration of the resveratrol analogues isorhapontigenin and heyneanol-A protects mice hematopoietic cells against irradiation injuries.
BioMed research international
Wang H,Yang YL,Zhang H,Yan H,Wu XJ,Zhang CZ
17-0031 was used in Flow cytometry/Cell sorting to examine if isorhapontigenin and heyneanol-A, two analogues of resveratrol, could mitigate IR-induced BM suppression.
Mon Mar 30 00:00:00 UTC 2015
Tim-3 negatively mediates natural killer cell function in LPS-induced endotoxic shock.
PloS one
Hou H,Liu W,Wu S,Lu Y,Peng J,Zhu Y,Lu Y,Wang F,Sun Z
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Mon Jul 06 00:00:00 UTC 2015
Autophagy is a critical regulator of memory CD8(+) T cell formation.
eLife
Puleston DJ,Zhang H,Powell TJ,Lipina E,Sims S,Panse I,Watson AS,Cerundolo V,Townsend AR,Klenerman P,Simon AK
17-0031 was used in Flow cytometry/Cell sorting to show that mice lacking the autophagy gene Atg7 in T cells failed to establish CD8(+) T cell memory to influenza and MCMV infection.
Tue Nov 11 00:00:00 UTC 2014
The nucleotide-binding leucine-rich repeat (NLR) family member NLRX1 mediates protection against experimental autoimmune encephalomyelitis and represses macrophage/microglia-induced inflammation.
The Journal of biological chemistry
Eitas TK,Chou WC,Wen H,Gris D,Robbins GR,Brickey J,Oyama Y,Ting JP
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Fri Feb 14 00:00:00 UTC 2014
HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis.
Blood
Franke K,Kalucka J,Mamlouk S,Singh RP,Muschter A,Weidemann A,Iyengar V,Jahn S,Wieczorek K,Geiger K,Muders M,Sykes AM,Poitz DM,Ripich T,Otto T,Bergmann S,Breier G,Baretton G,Fong GH,Greaves DR,Bornstein S,Chavakis T,Fandrey J,Gassmann M,Wielockx B
17-0031 was used in Flow cytometry/Cell sorting to study the regulatory effects of oxygen-sensitive prolyl hydroxylases on the process of erythropoiesis.
Thu Feb 21 00:00:00 UTC 2013
Group X secreted phospholipase A2 limits the development of atherosclerosis in LDL receptor-null mice.
Arteriosclerosis, thrombosis, and vascular biology
Ait-Oufella H,Herbin O,Lahoute C,Coatrieux C,Loyer X,Joffre J,Laurans L,Ramkhelawon B,Blanc-Brude O,Karabina S,Girard CA,Payré C,Yamamoto K,Binder CJ,Murakami M,Tedgui A,Lambeau G,Mallat Z
17-0031 was used in Flow cytometry/Cell sorting to study the proatherogenic properties of PLA2G10, a type of several secreted phospholipase A2.
Fri Mar 01 00:00:00 UTC 2013
B cells regulate neutrophilia during Mycobacterium tuberculosis infection and BCG vaccination by modulating the interleukin-17 response.
PLoS pathogens
Kozakiewicz L,Chen Y,Xu J,Wang Y,Dunussi-Joannopoulos K,Ou Q,Flynn JL,Porcelli SA,Jacobs WR,Chan J
17-0031 was used in Flow cytometry/Cell sorting to investigate the mechanisms by which B cells regulate the host neutrophilic response upon exposure to mycobacteria, showing that they do this by modulating the interleukin-17 response.
Tue Feb 18 00:00:00 UTC 2014
Distinct temporal requirements for Runx1 in hematopoietic progenitors and stem cells.
Development (Cambridge, England)
Tober J,Yzaguirre AD,Piwarzyk E,Speck NA
17-0031 was used in Flow cytometry/Cell sorting to study how the requirements for Runx1 in erythroid/myeloid progenitors and hematopoietic stem cell formation are temporally distinct.
Sun Sep 01 00:00:00 UTC 2013
Cbx4 regulates the proliferation of thymic epithelial cells and thymus function.
Development (Cambridge, England)
Liu B,Liu YF,Du YR,Mardaryev AN,Yang W,Chen H,Xu ZM,Xu CQ,Zhang XR,Botchkarev VA,Zhang Y,Xu GL
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Fri Feb 01 00:00:00 UTC 2013
Arrayed lentiviral barcoding for quantification analysis of hematopoietic dynamics.
Stem cells (Dayton, Ohio)
Grosselin J,Sii-Felice K,Payen E,Chretien S,Tronik-Le Roux D,Leboulch P
17-0031-82 was used in Flow Cytometry to demonstrate arrayed lentiviral barcoding as a versatile and powerful approach to deconvolute cell dynamics in vivo with applications in hematology, embryology, and cancer biology.
Tue Oct 01 00:00:00 UTC 2013
High frequencies of activated B cells and T follicular helper cells are correlated with disease activity in patients with new-onset rheumatoid arthritis.
Clinical and experimental immunology
Wang J,Shan Y,Jiang Z,Feng J,Li C,Ma L,Jiang Y
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Fri Nov 01 00:00:00 UTC 2013
The novel role of IL-7 ligation to IL-7 receptor in myeloid cells of rheumatoid arthritis and collagen-induced arthritis.
Journal of immunology (Baltimore, Md. : 1950)
Chen Z,Kim SJ,Chamberlain ND,Pickens SR,Volin MV,Volkov S,Arami S,Christman JW,Prabhakar BS,Swedler W,Mehta A,Sweiss N,Shahrara S
17-0031 was used in Flow cytometry/Cell sorting to study the role of IL7/IL7R in myeloid cells of rheumatoid arthritis and collagen induced arthritis.
Wed May 15 00:00:00 UTC 2013
Role of high endothelial venule-expressed heparan sulfate in chemokine presentation and lymphocyte homing.
Journal of immunology (Baltimore, Md. : 1950)
Tsuboi K,Hirakawa J,Seki E,Imai Y,Yamaguchi Y,Fukuda M,Kawashima H
17-0031 was used in Flow cytometry/Cell sorting to suggest that chemokine presentation by heparan sulfate on the surface of high endothelial venules facilitates lymphocyte homing.
Mon Jul 01 00:00:00 UTC 2013
n3 PUFAs reduce mouse CD4+ T-cell ex vivo polarization into Th17 cells.
The Journal of nutrition
Monk JM,Hou TY,Turk HF,McMurray DN,Chapkin RS
17-0031 was used in Flow cytometry/Cell sorting to discern the effect of n3 PUFAs on the CD4+ T-cells of mice.
Sun Sep 01 00:00:00 UTC 2013
Ontogeny and localization of the cells produce IL-2 in healthy animals.
Cytokine
Yamamoto M,Seki Y,Iwai K,Ko I,Martin A,Tsuji N,Miyagawa S,Love RB,Iwashima M
17-0031 was used in Flow cytometry/Cell sorting to study how a group of Tr1 cells may have additional roles in immune homeostasis through IL-2 production to aid in the maintenance of other regulatory T cells..
Fri Mar 01 00:00:00 UTC 2013
Myxomaviral Anti-Inflammatory Serpin Reduces Myeloid-Derived Suppressor Cells and Human Pancreatic Cancer Cell Growth in Mice.
Journal of cancer science & therapy
Zheng D,Chen H,Bartee MY,Williams J,Davids JA,Lomas DA,McFadden G,Lucas AR
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Mon Aug 19 00:00:00 UTC 2013
Us3 kinase encoded by herpes simplex virus 1 mediates downregulation of cell surface major histocompatibility complex class I and evasion of CD8+ T cells.
PloS one
Imai T,Koyanagi N,Ogawa R,Shindo K,Suenaga T,Sato A,Arii J,Kato A,Kiyono H,Arase H,Kawaguchi Y
17-0031 was used in Flow cytometry/Cell sorting to reveal that Us3 kinase activity is required for influencing cell surface expression for evasion of HSV-1-specific CD8(+) T cells.
Tue Apr 15 00:00:00 UTC 2014
Mast cells contribute to double-stranded RNA-induced augmentation of airway eosinophilia in a murine model of asthma.
Respiratory research
Kan-o K,Matsunaga Y,Fukuyama S,Moriwaki A,Hirai-Kitajima H,Yokomizo T,Aritake K,Urade Y,Nakanishi Y,Inoue H,Matsumoto K
17-0031 was used in Flow cytometry/Cell sorting to determine the role of mast cells in the virus-associated pathogenesis of asthma.
Mon Mar 04 00:00:00 UTC 2013
Resistance to malaria by enhanced phagocytosis of erythrocytes in LMP7-deficient mice.
PloS one
Duan X,Imai T,Chou B,Tu L,Himeno K,Suzue K,Hirai M,Taniguchi T,Okada H,Shimokawa C,Hisaeda H
17-0031 was used in Flow cytometry/Cell sorting to study how RBCs of LMP7-deficient mice were more likely to deform in response to infection with malaria parasites.
Tue Sep 17 00:00:00 UTC 2013
Partial depletion of regulatory T cells does not influence the inflammation caused by high dose hemi-body irradiation.
PloS one
Ma S,Richardson JA,Bitmansour A,Solberg TD,Pidikiti R,Song K,Stojadinovic S,Vitetta ES,Meyer JJ
17-0031 was used in Flow cytometry/Cell sorting to investigate the effects of partial depletion of regulatory T cells alongside ionizing radiation on inflammation and tissue injury in mice.
Mon Jul 29 00:00:00 UTC 2013
Rank signaling links the development of invariant γδ T cell progenitors and Aire(+) medullary epithelium.
Immunity
Roberts NA,White AJ,Jenkinson WE,Turchinovich G,Nakamura K,Withers DR,McConnell FM,Desanti GE,Benezech C,Parnell SM,Cunningham AF,Paolino M,Penninger JM,Simon AK,Nitta T,Ohigashi I,Takahama Y,Caamano JH,Hayday AC,Lane PJ,Jenkinson EJ,Anderson G
17-0031 was used in Flow cytometry/Cell sorting to study the temporal development of Vγ5(+) γδ T cells during thymus medulla formation.
Fri Mar 23 00:00:00 UTC 2012
Loss of T cell microRNA provides systemic protection against autoimmune pathology in mice.
Journal of autoimmunity
Tian L,De Hertogh G,Fedeli M,Staats KA,Schonefeldt S,Humblet-Baron S,Van Den Bosch L,Dellabona P,Dooley J,Liston A
17-0031 was used in Flow cytometry/Cell sorting to elucidate the dominant effects of the T cell microRNA expression network and explore it as a potential therapeutic target for autoimmune diseases.
Wed Feb 01 00:00:00 UTC 2012
Characterization of an arachidonic acid-deficient (Fads1 knockout) mouse model.
Journal of lipid research
Fan YY,Monk JM,Hou TY,Callway E,Vincent L,Weeks B,Yang P,Chapkin RS
17-0031 was used in Flow cytometry/Cell sorting to determine the utility of antagonising tissue arachidonic acid (AA) levels as a novel approach to suppress AA-derived eicosanoids.
Sun Jul 01 00:00:00 UTC 2012
Pulmonary T cell activation in response to chronic particulate air pollution.
American journal of physiology. Lung cellular and molecular physiology
Deiuliis JA,Kampfrath T,Zhong J,Oghumu S,Maiseyeu A,Chen LC,Sun Q,Satoskar AR,Rajagopalan S
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Wed Feb 15 00:00:00 UTC 2012
The Thai phase III trial (RV144) vaccine regimen induces T cell responses that preferentially target epitopes within the V2 region of HIV-1 envelope.
Journal of immunology (Baltimore, Md. : 1950)
de Souza MS,Ratto-Kim S,Chuenarom W,Schuetz A,Chantakulkij S,Nuntapinit B,Valencia-Micolta A,Thelian D,Nitayaphan S,Pitisuttithum P,Paris RM,Kaewkungwal J,Michael NL,Rerks-Ngarm S,Mathieson B,Marovich M,Currier JR,Kim JH
17-0031 was used in Flow cytometry/Cell sorting to reveal T cell response of HIV-1 vaccine recipients was directed to a particular region of viral envelope.
Tue May 15 00:00:00 UTC 2012
TLR9 and MyD88 are crucial for the development of protective immunity to malaria.
Journal of immunology (Baltimore, Md. : 1950)
Gowda NM,Wu X,Gowda DC
17-0031 was used in Flow cytometry/Cell sorting to investigate TLR9 and MyD88 regulation of pro/anti-inflammatory cytokines in mice infected with Plasmodium yoelii.
Tue May 15 00:00:00 UTC 2012
Effect of the poly(ethylene glycol) (PEG) density on the access and uptake of particles by antigen-presenting cells (APCs) after subcutaneous administration.
Molecular pharmaceutics
Zhan X,Tran KK,Shen H
17-0031 was used in Flow cytometry/Cell sorting to study the effect of PEGylation on the lymphatic trafficking and accumulation of particles in draining lymph nodes.
Mon Dec 03 00:00:00 UTC 2012
Spontaneous autoimmune gastritis and hypochlorhydria are manifest in the ileitis-prone SAMP1/YitFcs mice.
American journal of physiology. Gastrointestinal and liver physiology
Ernst PB,Erickson LD,Loo WM,Scott KG,Wiznerowicz EB,Brown CC,Torres-Velez FJ,Alam MS,Black SG,McDuffie M,Feldman SH,Wallace JL,McKnight GW,Padol IT,Hunt RH,Tung KS
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Sun Jan 01 00:00:00 UTC 2012
Evaluation of Lassa virus vaccine immunogenicity in a CBA/J-ML29 mouse model.
Vaccine
Goicochea MA,Zapata JC,Bryant J,Davis H,Salvato MS,Lukashevich IS
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Tue Feb 14 00:00:00 UTC 2012
Host response signature to Staphylococcus aureus alpha-hemolysin implicates pulmonary Th17 response.
Infection and immunity
Frank KM,Zhou T,Moreno-Vinasco L,Hollett B,Garcia JG,Bubeck Wardenburg J
17-0031 was used in Flow cytometry/Cell sorting to evaluate the transcriptomic response to Hla-secreting staphylococci infection in humans.
Sat Sep 01 00:00:00 UTC 2012
MyD88-dependent recruitment of monocytes and dendritic cells required for protection from pulmonary Burkholderia mallei infection.
Infection and immunity
Goodyear A,Troyer R,Bielefeldt-Ohmann H,Dow S
17-0031 was used in Flow cytometry/Cell sorting to find that MyD88-/- mice were highly susceptible to pulmonary challenge with B. mallei and had significantly short survival times, increased bacterial burdens, and severe organ pathology compared to wild-type mice.
Sun Jan 01 00:00:00 UTC 2012
Species-specific activity of glycolipid ligands for invariant NKT cells.
Chembiochem : a European journal of chemical biology
Dangerfield EM,Cheng JM,Knight DA,Weinkove R,Dunbar PR,Hermans IF,Timmer MS,Stocker BL
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Mon Jun 18 00:00:00 UTC 2012
Loss of the methyl lysine effector protein PHF20 impacts the expression of genes regulated by the lysine acetyltransferase MOF.
The Journal of biological chemistry
Badeaux AI,Yang Y,Cardenas K,Vemulapalli V,Chen K,Kusewitt D,Richie E,Li W,Bedford MT
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Mon Jan 02 00:00:00 UTC 2012
Soluble MOG35-55/I-A(b) dimers ameliorate experimental autoimmune encephalomyelitis by reducing encephalitogenic T cells.
PloS one
Gong Y,Wang Z,Liang Z,Duan H,Ouyang L,Yu Q,Xu Z,Shen G,Weng X,Wu X
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Fri Jul 19 00:00:00 UTC 2013
Deleterious effect of the IL-23/IL-17A axis and γδT cells on left ventricular remodeling after myocardial infarction.
Journal of the American Heart Association
Yan X,Shichita T,Katsumata Y,Matsuhashi T,Ito H,Ito K,Anzai A,Endo J,Tamura Y,Kimura K,Fujita J,Shinmura K,Shen W,Yoshimura A,Fukuda K,Sano M
17-0031 was used in Flow cytometry/Cell sorting to explore potential immune pathways involved in left ventricular remodelling as possible preventative therapeutic options.
Mon Oct 01 00:00:00 UTC 2012
Increased synapse formation obtained by T cell epitopes containing a CxxC motif in flanking residues convert CD4+ T cells into cytolytic effectors.
PloS one
Carlier VA,VanderElst L,Janssens W,Jacquemin MG,Saint-Remy JM
17-0031 was used in Flow cytometry/Cell sorting to investigate the conditions under which cytolytic CD4+ T cells are elicited.
Tue Apr 02 00:00:00 UTC 2013
Essential role of peripheral node addressin in lymphocyte homing to nasal-associated lymphoid tissues and allergic immune responses.
The Journal of experimental medicine
Ohmichi Y,Hirakawa J,Imai Y,Fukuda M,Kawashima H
17-0031 was used in Flow cytometry/Cell sorting to demonstrate that PNAd is essential for lymphocyte homing to NALT and nasal allergic responses.
Mon May 09 00:00:00 UTC 2011
Magnetic-based purification of untouched mouse germinal center B cells for ex vivo manipulation and biochemical analysis.
Nature protocols
Cato MH,Yau IW,Rickert RC
17-0031 was used in Magnetic cell separation to provide a protocol for a novel magnetic bead separation scheme for the purification of mature B cells for biochemical assessment.
Thu Jun 09 00:00:00 UTC 2011
Sertoli cell-specific deletion of the androgen receptor compromises testicular immune privilege in mice.
Biology of reproduction
Meng J,Greenlee AR,Taub CJ,Braun RE
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Mon Aug 01 00:00:00 UTC 2011
Prevention of NKT cell activation accelerates cutaneous wound closure and alters local inflammatory signals.
The Journal of surgical research
Schneider DF,Palmer JL,Tulley JM,Kovacs EJ,Gamelli RL,Faunce DE
17-0031 was used in Flow cytometry/Cell sorting to explore the effects of purposefully inhibiting natural killer T cell activation on the response to injury.
Tue Nov 01 00:00:00 UTC 2011
An improved cell isolation method for flow cytometric and functional analyses of cutaneous wound leukocytes.
Journal of immunological methods
Brubaker AL,Schneider DF,Palmer JL,Faunce DE,Kovacs EJ
17-0031 was used in Flow cytometry/Cell sorting to develop a method for preparing wound cell suspensions for further study.
Fri Oct 28 00:00:00 UTC 2011
T cell-intrinsic and -extrinsic contributions of the IFNAR/STAT1-axis to thymocyte survival.
PloS one
Moro H,Otero DC,Tanabe Y,David M
17-0031 was used in Flow cytometry/Cell sorting to demonstrate that type I interferons and STAT1 play an important role in the survival of MHC class I-restricted T cells.
Fri Feb 03 00:00:00 UTC 2012
Rapid immunomagnetic negative enrichment of neutrophil granulocytes from murine bone marrow for functional studies in vitro and in vivo.
PloS one
Hasenberg M,Köhler A,Bonifatius S,Borucki K,Riek-Burchardt M,Achilles J,Männ L,Baumgart K,Schraven B,Gunzer M
17-0031 was used in Flow cytometry/Cell sorting to develop a novel protocol for isolating pure polymorphonuclear neutrophils from murine bone marrow.
Wed Feb 23 00:00:00 UTC 2011
Chronic cigarette smoke exposure generates pathogenic T cells capable of driving COPD-like disease in Rag2-/- mice.
American journal of respiratory and critical care medicine
Motz GT,Eppert BL,Wesselkamper SC,Flury JL,Borchers MT
17-0031 was used in Flow cytometry/Cell sorting to determine whether T cells are pathogenic in a chronic cigarette smoke-induced mouse model of chronic obstructive pulmonary disease.
Tue Jun 01 00:00:00 UTC 2010
TLR8 deficiency leads to autoimmunity in mice.
The Journal of clinical investigation
Demaria O,Pagni PP,Traub S,de Gassart A,Branzk N,Murphy AJ,Valenzuela DM,Yancopoulos GD,Flavell RA,Alexopoulou L
17-0031 was used in Flow cytometry/Cell sorting to explore the relationship between TLR8 and TLR7 and autoimmunity in mice.
Fri Oct 01 00:00:00 UTC 2010
T-cell recruitment and Th1 polarization in adipose tissue during diet-induced obesity in C57BL/6 mice.
Obesity (Silver Spring, Md.)
Strissel KJ,DeFuria J,Shaul ME,Bennett G,Greenberg AS,Obin MS
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Fri Oct 01 00:00:00 UTC 2010
BTN1A1, the mammary gland butyrophilin, and BTN2A2 are both inhibitors of T cell activation.
Journal of immunology (Baltimore, Md. : 1950)
Smith IA,Knezevic BR,Ammann JU,Rhodes DA,Aw D,Palmer DB,Mather IH,Trowsdale J
17-0031 was used in Flow cytometry/Cell sorting to confirm a coinhibitory role for mouse BTN1A1.
Thu Apr 01 00:00:00 UTC 2010
Chronic cigarette smoke exposure primes NK cell activation in a mouse model of chronic obstructive pulmonary disease.
Journal of immunology (Baltimore, Md. : 1950)
Motz GT,Eppert BL,Wortham BW,Amos-Kroohs RM,Flury JL,Wesselkamper SC,Borchers MT
17-0031 was used in Flow cytometry/Cell sorting to demonstrate an entirely novel mechanism of NK cell activation resulting from chronic cigarette smoke exposure.
Thu Apr 15 00:00:00 UTC 2010
Interleukin-6 contributes to age-related alteration of cytokine production by macrophages.
Mediators of inflammation
Gomez CR,Karavitis J,Palmer JL,Faunce DE,Ramirez L,Nomellini V,Kovacs EJ
17-0031 was used in Flow cytometry/Cell sorting to demonstrate in vitro that Interleukin-6 regulates age-related defects in splenic macrophages through alteration of proinflammatory cytokines.
Thu Nov 04 00:00:00 UTC 2010
Influence of 5 major Salmonella pathogenicity islands on NK cell depletion in mice infected with Salmonella enterica serovar Enteritidis.
BMC microbiology
Karasova D,Sebkova A,Havlickova H,Sisak F,Volf J,Faldyna M,Ondrackova P,Kummer V,Rychlik I
17-0031 was used in Flow cytometry/Cell sorting to investigate the colonisation and early immune response of Balb/C mice to infection with Salmonella Enteritidis and isogenic pathogenicity island free mutants.
Fri Mar 12 00:00:00 UTC 2010
Expression of the chemokine binding protein M3 promotes marked changes in the accumulation of specific leukocytes subsets within the intestine.
Gastroenterology
Shang L,Thirunarayanan N,Viejo-Borbolla A,Martin AP,Bogunovic M,Marchesi F,Unkeless JC,Ho Y,Furtado GC,Alcami A,Merad M,Mayer L,Lira SA
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Tue Sep 01 00:00:00 UTC 2009
Effect of polyI:C cotreatment on halothane-induced liver injury in mice.
Hepatology (Baltimore, Md.)
Cheng L,You Q,Yin H,Holt M,Franklin C,Ju C
17-0031 was used in Flow cytometry/Cell sorting to investigate the effect of viral infection on halothane-induced hepatotoxicity in mice using a viral RNA mimetic.
Thu Jan 01 00:00:00 UTC 2009
Tracking epitope-specific T cells.
Nature protocols
Moon JJ,Chu HH,Hataye J,Pagán AJ,Pepper M,McLachlan JB,Zell T,Jenkins MK
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Tue Jun 30 00:00:00 UTC 2009
Isolated CD39 expression on CD4+ T cells denotes both regulatory and memory populations.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Zhou Q,Yan J,Putheti P,Wu Y,Sun X,Toxavidis V,Tigges J,Kassam N,Enjyoji K,Robson SC,Strom TB,Gao W
17-0031 was used in Flow cytometry/Cell sorting to study how besides Tregs, CD39 is also expressed on pre-existing memory T cells of Th1-, Th2- and Th17-types with heightened alloreactivity.
Thu Oct 01 00:00:00 UTC 2009
Differential IL-23 requirement for IL-22 and IL-17A production during innate immunity against Salmonella enterica serovar Enteritidis.
International immunology
Siegemund S,Schütze N,Schulz S,Wolk K,Nasilowska K,Straubinger RK,Sabat R,Alber G
17-0031 was used in Flow cytometry/Cell sorting to study whether IL-22 and IL-17A production is initiated early in response to S. Enteritidis, showing that early production of IL-22 was dependent on IL-23, however IL-17A was only partially IL-23-dependent.
Fri May 01 00:00:00 UTC 2009
Dynamics of lung macrophage activation in response to helminth infection.
Journal of leukocyte biology
Siracusa MC,Reece JJ,Urban JF,Scott AL
17-0031 was used in Flow cytometry/Cell sorting to characterise the surface molecules, gene expression, and cell function of macrophages isolated from lung tissue after helminth infection.
Mon Dec 01 00:00:00 UTC 2008
Loss of extracellular superoxide dismutase leads to acute lung damage in the presence of ambient air: a potential mechanism underlying adult respiratory distress syndrome.
The American journal of pathology
Gongora MC,Lob HE,Landmesser U,Guzik TJ,Martin WD,Ozumi K,Wall SM,Wilson DS,Murthy N,Gravanis M,Fukai T,Harrison DG
17-0031 was used in Flow cytometry/Cell sorting to study the role of acute SOD3 reduction in lung injury.
Wed Oct 01 00:00:00 UTC 2008
Unique receptor repertoire in mouse uterine NK cells.
Journal of immunology (Baltimore, Md. : 1950)
Yadi H,Burke S,Madeja Z,Hemberger M,Moffett A,Colucci F
17-0031-82 was used in Flow Cytometry to define the receptor repertoire and phenotype of uterine NK cells at mid-gestation in mice.
Sat Nov 01 00:00:00 UTC 2008
p27 deficiency cooperates with Bcl-2 but not Bax to promote T-cell lymphoma.
PloS one
Cheng N,van de Wetering CI,Knudson CM
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Wed Apr 02 00:00:00 UTC 2008
Tumor growth decreases NK and B cells as well as common lymphoid progenitor.
PloS one
Richards J,McNally B,Fang X,Caligiuri MA,Zheng P,Liu Y
17-0031 was used in Flow cytometry/Cell sorting to analyse the effects of tumour growth on lymphopoiesis in mice.
Thu Sep 11 00:00:00 UTC 2008
Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity.
Immunity
Fritz JH,Le Bourhis L,Sellge G,Magalhaes JG,Fsihi H,Kufer TA,Collins C,Viala J,Ferrero RL,Girardin SE,Philpott DJ
17-0031 was used in Flow cytometry/Cell sorting to examine the role of the Nod1 receptor in the generation of adaptive immune responses.
Sun Apr 01 00:00:00 UTC 2007
Dendritic cells prime natural killer cells by trans-presenting interleukin 15.
Immunity
Lucas M,Schachterle W,Oberle K,Aichele P,Diefenbach A
17-0031 was used in Flow cytometry/Cell sorting to study an in vivo role of dendritic cells for the priming of natural killer cells by trans-presenting interleukin 15.
Sun Apr 01 00:00:00 UTC 2007
Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling.
Proceedings of the National Academy of Sciences of the United States of America
Tsuji M,Shinkura R,Kuroda K,Yabe D,Honjo T
17-0031-82 was used in Flow Cytometry to o investigate where and how Notch regulates early T cell differentiation by using specific up-regulation of Notch signaling by Mint knockout.
Tue Jan 30 00:00:00 UTC 2007
The mouse mammary carcinoma 4T1: characterization of the cellular landscape of primary tumours and metastatic tumour foci.
International journal of experimental pathology
DuPré SA,Redelman D,Hunter KW
Published figure using CD3e monoclonal antibody (Product # 17-0031-82) in Flow Cytometry
Mon Oct 01 00:00:00 UTC 2007
ADAM17 deficiency by mature neutrophils has differential effects on L-selectin shedding.
Blood
Li Y,Brazzell J,Herrera A,Walcheck B
17-0031 was used in Flow cytometry/Cell sorting to investigate the role of Adam17 in L-selectin shedding by mature neutrophils, showing that deficiency by mature neutrophils has differential effects on L-selectin shedding.
Sun Oct 01 00:00:00 UTC 2006
Tumor growth impedes natural-killer-cell maturation in the bone marrow.
Blood
Richards JO,Chang X,Blaser BW,Caligiuri MA,Zheng P,Liu Y
17-0031 was used in Flow cytometry/Cell sorting to demonstrate that tumour growth can impede functional maturation of NK cells, most likely by interrupting the requisite IL-15 signalling pathway.
Sat Jul 01 00:00:00 UTC 2006
HSP70 vaccine in combination with gene therapy with plasmid DNA encoding sPD-1 overcomes immune resistance and suppresses the progression of pulmonary metastatic melanoma.
International journal of cancer
Geng H,Zhang GM,Xiao H,Yuan Y,Li D,Zhang H,Qiu H,He YF,Feng ZH
Thu Jun 01 00:00:00 UTC 2006
Mast cells enhance T cell activation: Importance of mast cell-derived TNF.
Proceedings of the National Academy of Sciences of the United States of America
Nakae S,Suto H,Kakurai M,Sedgwick JD,Tsai M,Galli SJ
17-0031 was used in Functional assays to investigate the mechanisms by which mast cells influence T cells in T cell-mediated disorders, showing that they enhance activation.
Tue May 03 00:00:00 UTC 2005
Functional analysis of B and T lymphocyte attenuator engagement on CD4+ and CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950)
Krieg C,Han P,Stone R,Goularte OD,Kaye J
Tue Nov 15 00:00:00 UTC 2005
CCR5-deficient mice develop experimental autoimmune uveoretinitis in the context of a deviant effector response.
Investigative ophthalmology & visual science
Takeuchi A,Usui Y,Takeuchi M,Hattori T,Kezuka T,Suzuki J,Okunuki Y,Iwasaki T,Haino M,Matsushima K,Usui M
Sat Oct 01 00:00:00 UTC 2005
The extracellular human melanoma inhibitory activity (MIA) protein adopts an SH3 domain-like fold.
The EMBO journal
Stoll R,Renner C,Zweckstetter M,Brüggert M,Ambrosius D,Palme S,Engh RA,Golob M,Breibach I,Buettner R,Voelter W,Holak TA,Bosserhoff AK
17-0031 was used in Flow cytometry/Cell sorting to investigate the role of MIA in metastasis, showing that it adopts an SH3 domain-like fold.
Thu Feb 01 00:00:00 UTC 2001
