Product References
Cathepsin S inhibition in dendritic cells prevents Th17 cell differentiation in perivascular adipose tissues following vascular injury in diabetic rats.
Journal of biochemical and molecular toxicology
Peng H,Lv Y,Li C,Cheng Z,He S,Wang C,Liu J
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Fri Sep 01 00:00:00 EDT 2023
Purinergic receptor P2Y12 boosts autoimmune hepatitis through hexokinase 2-dependent glycolysis in T cells.
International journal of biological sciences
Zhuang W,Liu X,Liu G,Lv J,Qin H,Wang C,Xie L,Saimaier K,Han S,Shi C,Hua Q,Zhang R,Du C
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Thu Aug 03 00:00:00 EDT 2023
Rapamycin improves Graves' orbitopathy by suppressing CD4+ cytotoxic T lymphocytes.
JCI insight
Zhang M,Chong KK,Chen ZY,Guo H,Liu YF,Kang YY,Li YJ,Shi TT,Lai KK,He MQ,Ye K,Kahaly GJ,Shi BY,Wang Y
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Wed Feb 08 00:00:00 EST 2023
Single-cell RNA sequencing reveals the molecular features of peripheral blood immune cells in children, adults and centenarians.
Frontiers in immunology
Zhong J,Ding R,Jiang H,Li L,Wan J,Feng X,Chen M,Peng L,Li X,Lin J,Yang H,Wang M,Li Q,Chen Q
25-0049-42 was used in Flow cytometry/Cell sorting to profile peripheral blood mononuclear cells (PBMCs) of multiple age groups.
Mon Jan 30 00:00:00 EST 2023
Single-cell RNA sequencing reveals the molecular features of peripheral blood immune cells in children, adults and centenarians.
Frontiers in immunology
Zhong J,Ding R,Jiang H,Li L,Wan J,Feng X,Chen M,Peng L,Li X,Lin J,Yang H,Wang M,Li Q,Chen Q
25-0049-42 was used in Flow cytometry/Cell sorting to profile peripheral blood mononuclear cells (PBMCs) of multiple age groups.
Mon Jan 30 00:00:00 EST 2023
Single-cell profiling of healthy human kidney reveals features of sex-based transcriptional programs and tissue-specific immunity.
Nature communications
McEvoy CM,Murphy JM,Zhang L,Clotet-Freixas S,Mathews JA,An J,Karimzadeh M,Pouyabahar D,Su S,Zaslaver O,Röst H,Arambewela R,Liu LY,Zhang S,Lawson KA,Finelli A,Wang B,MacParland SA,Bader GD,Konvalinka A,Crome SQ
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Sat Dec 10 00:00:00 EST 2022
Decoding the pathogenesis of Diamond-Blackfan anemia using single-cell RNA-seq.
Cell discovery
Wang B,Wang C,Wan Y,Gao J,Ma Y,Zhang Y,Tong J,Zhang Y,Liu J,Chang L,Xu C,Shen B,Chen Y,Jiang E,Kurita R,Nakamura Y,Lim KC,Engel JD,Zhou J,Cheng T,Zhu X,Zhu P,Shi L
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Tue May 10 00:00:00 EDT 2022
Effects of the Antidiabetic Drugs Evogliptin and Sitagliptin on the Immune Function of CD26/DPP4 in Th1 Cells.
Biomolecules & therapeutics
Yoon H,Sung JH,Song MJ
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Mon Mar 01 00:00:00 EST 2021
DNAM1 and TIGIT balance the T cell response, with low T cell TIGIT expression corresponding to inflammation in psoriatic disease.
Immunotherapy advances
Jacobs ME,Pouw JN,Olde Nordkamp MA,Radstake TRDJ,Leijten EFA,Boes M
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Murlentamab, a Low Fucosylated Anti-Müllerian Hormone Type II Receptor (AMHRII) Antibody, Exhibits Anti-Tumor Activity through Tumor-Associated Macrophage Reprogrammation and T Cell Activation.
Cancers
Prat M,Salon M,Allain T,Dubreuil O,Noël G,Preisser L,Jean B,Cassard L,Lemée F,Tabah-Fish I,Pipy B,Jeannin P,Prost JF,Barret JM,Coste A
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Tue Apr 13 00:00:00 EDT 2021
Characterization and modulation of anti-αβTCR antibodies and their respective binding sites at the βTCR chain to enrich engineered T cells.
Molecular therapy. Methods & clinical development
Kierkels GJJ,van Diest E,Hernández-López P,Scheper W,de Bruin ACM,Frijlink E,Aarts-Riemens T,van Dooremalen SFJ,Beringer DX,Oostvogels R,Kramer L,Straetemans T,Uckert W,Sebestyén Z,Kuball J
25-0049-42 was used in Flow Cytometry to engineer an antibody that targets an extended mutated interface of 9 amino acids in the TCRβ chain constant domain and provides the opportunity to further develop depletion strategies of engineered immune cells.
Fri Sep 10 00:00:00 EDT 2021
Characterization and modulation of anti-αβTCR antibodies and their respective binding sites at the βTCR chain to enrich engineered T cells.
Molecular therapy. Methods & clinical development
Kierkels GJJ,van Diest E,Hernández-López P,Scheper W,de Bruin ACM,Frijlink E,Aarts-Riemens T,van Dooremalen SFJ,Beringer DX,Oostvogels R,Kramer L,Straetemans T,Uckert W,Sebestyén Z,Kuball J
25-0049-42 was used in Flow Cytometry to engineer an antibody that targets an extended mutated interface of 9 amino acids in the TCRβ chain constant domain and provides the opportunity to further develop depletion strategies of engineered immune cells.
Fri Sep 10 00:00:00 EDT 2021
Bispecific T-Cell Engaging Antibodies Against MUC16 Demonstrate Efficacy Against Ovarian Cancer in Monotherapy and in Combination With PD-1 and VEGF Inhibition.
Frontiers in immunology
Yeku OO,Rao TD,Laster I,Kononenko A,Purdon TJ,Wang P,Cui Z,Liu H,Brentjens RJ,Spriggs D
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Thu Oct 21 00:00:00 EDT 2021
Identification of two HLA-A*0201 immunogenic epitopes of lactate dehydrogenase C (LDHC): potential novel targets for cancer immunotherapy.
Cancer immunology, immunotherapy : CII
Thomas R,Shaath H,Naik A,Toor SM,Elkord E,Decock J
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2020
HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment.
Journal of Cancer
Kim YD,Park SM,Ha HC,Lee AR,Won H,Cha H,Cho S,Cho JM
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2020
Involvement of natural killer cells in the pathogenesis of endometriosis in patients with pelvic pain.
The Journal of international medical research
He J,Xu Y,Yi M,Gu C,Zhu Y,Hu G
25-0049 was used in Flow cytometry/Cell sorting to investigate the involvement of immune cells in the pathogenesis of endometriosis progression by analyzing blood samples from patients with stable disease and those with pelvic pain.
Wed Jul 01 00:00:00 EDT 2020
Involvement of natural killer cells in the pathogenesis of endometriosis in patients with pelvic pain.
The Journal of international medical research
He J,Xu Y,Yi M,Gu C,Zhu Y,Hu G
25-0049 was used in Flow cytometry/Cell sorting to investigate the involvement of immune cells in the pathogenesis of endometriosis progression by analyzing blood samples from patients with stable disease and those with pelvic pain.
Wed Jul 01 00:00:00 EDT 2020
Standardized 11-color flow cytometry panel for the functional phenotyping of human T regulatory cells.
Journal of biological methods
Manuszak C,Brainard M,Thrash E,Hodi FS,Severgnini M
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2020
MicroRNA‑155 inhibits the proliferation of CD8+ T cells via upregulating regulatory T cells in vitiligo.
Molecular medicine reports
Lv M,Li Z,Liu J,Lin F,Zhang Q,Li Z,Wang Y,Wang K,Xu Y
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
Two phase kinetics of the inflammatory response from hepatocyte-peripheral blood mononuclear cell interactions.
Scientific reports
Beringer A,Molle J,Bartosch B,Miossec P
25-0049 was used in Flow cytometry/Cell sorting to study the role of interactions between non and activated human peripheral blood mononuclear cells and human hepatoma HepaRG cells in the inflammatory response.
Mon Jun 10 00:00:00 EDT 2019
RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses.
Cell
Bradley T,Peppa D,Pedroza-Pacheco I,Li D,Cain DW,Henao R,Venkat V,Hora B,Chen Y,Vandergrift NA,Overman RG,Edwards RW,Woods CW,Tomaras GD,Ferrari G,Ginsburg GS,Connors M,Cohen MS,Moody MA,Borrow P,Haynes BF
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Thu Oct 04 00:00:00 EDT 2018
CXCL4 is a novel inducer of human Th17 cells and correlates with IL-17 and IL-22 in psoriatic arthritis.
European journal of immunology
Affandi AJ,Silva-Cardoso SC,Garcia S,Leijten EFA,van Kempen TS,Marut W,van Roon JAG,Radstake TRDJ
25-0049 was used in Flow cytometry/Cell sorting to study whether CXCL4 plays a direct role in the induction of IL-17 production by human CD4+ T cells.
Thu Mar 01 00:00:00 EST 2018
The Effects of High Mobility Group Box-1 Protein on Peripheral Treg/Th17 Balance in Patients with Atherosclerosis.
Acta Cardiologica Sinica
Ding JW,Zhou T,Zheng XX,Wang XA,Tong XH,Luo CY,Zhang ZQ,Yu B
25-0049 was used in Flow cytometry/Cell sorting to explore the mechanism of regulatory T cell/Th17 imbalance and the role of high mobility group box-1 protein on the balance in atherosclerosis.
Sat Sep 01 00:00:00 EDT 2018
Non-neutralizing Antibodies Alter the Course of HIV-1 Infection In Vivo.
Cell
Horwitz JA,Bar-On Y,Lu CL,Fera D,Lockhart AAK,Lorenzi JCC,Nogueira L,Golijanin J,Scheid JF,Seaman MS,Gazumyan A,Zolla-Pazner S,Nussenzweig MC
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Thu Aug 10 00:00:00 EDT 2017
Blocking the recruitment of naive CD4+ T cells reverses immunosuppression in breast cancer.
Cell research
Su S,Liao J,Liu J,Huang D,He C,Chen F,Yang L,Wu W,Chen J,Lin L,Zeng Y,Ouyang N,Cui X,Yao H,Su F,Huang JD,Lieberman J,Liu Q,Song E
25-0049 was used in Flow cytometry/Cell sorting to demonstrate that blocking PITPNM3 recognition of CCL18 could be an attractive immunotherapy aproach for treating breast cancer.
Sat Apr 01 00:00:00 EDT 2017
Accelerated resolution of inflammation underlies sex differences in inflammatory responses in humans.
The Journal of clinical investigation
Rathod KS,Kapil V,Velmurugan S,Khambata RS,Siddique U,Khan S,Van Eijl S,Gee LC,Bansal J,Pitrola K,Shaw C,D'Acquisto F,Colas RA,Marelli-Berg F,Dalli J,Ahluwalia A
25-0049 was used in Flow cytometry/Cell sorting to investigate whether inflammation and components of the inflammatory response are altered in females compared with males.
Tue Jan 03 00:00:00 EST 2017
Impact of Enhancer of Zeste Homolog 2 on T Helper Cell-Mediated Allergic Rhinitis.
Frontiers in immunology
Hou TY,Chen MR,Chou YC,Kan PC,Tsai YT,Cha TL
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Protein kinase CK2 controls T-cell polarization through dendritic cell activation in response to contact sensitizers.
Journal of leukocyte biology
de Bourayne M,Gallais Y,El Ali Z,Rousseau P,Damiens MH,Cochet C,Filhol O,Chollet-Martin S,Pallardy M,Kerdine-Römer S
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Decidual T Cells Exhibit a Highly Differentiated Phenotype and Demonstrate Potential Fetal Specificity and a Strong Transcriptional Response to IFN.
Journal of immunology (Baltimore, Md. : 1950)
Powell RM,Lissauer D,Tamblyn J,Beggs A,Cox P,Moss P,Kilby MD
25-0049 was used in Flow cytometry/Cell sorting to investigate the specificity and regulation of CD4+ and CD8+ T cells obtained from human third trimester decidua and demonstrated that decidual CD4+ and CD8+ T cells exhibit a highly differentiated effector memory phenotype in comparison with peripheral blood.
Wed Nov 15 00:00:00 EST 2017
CXCL13-producing TFH cells link immune suppression and adaptive memory in human breast cancer.
JCI insight
Gu-Trantien C,Migliori E,Buisseret L,de Wind A,Brohée S,Garaud S,Noël G,Dang Chi VL,Lodewyckx JN,Naveaux C,Duvillier H,Goriely S,Larsimont D,Willard-Gallo K
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Fri Jun 02 00:00:00 EDT 2017
IL-21 restricts T follicular regulatory T cell proliferation through Bcl-6 mediated inhibition of responsiveness to IL-2.
Nature communications
Jandl C,Liu SM,Cañete PF,Warren J,Hughes WE,Vogelzang A,Webster K,Craig ME,Uzel G,Dent A,Stepensky P,Keller B,Warnatz K,Sprent J,King C
25-0049 was used in Flow cytometry/Cell sorting to identify a mechanism by which IL-21 reinforces humoural immunity by influencing the phenotype of T follicular cells to limit their expansion.
Fri Mar 17 00:00:00 EDT 2017
Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity.
Science translational medicine
Dendrou CA,Cortes A,Shipman L,Evans HG,Attfield KE,Jostins L,Barber T,Kaur G,Kuttikkatte SB,Leach OA,Desel C,Faergeman SL,Cheeseman J,Neville MJ,Sawcer S,Compston A,Johnson AR,Everett C,Bell JI,Karpe F,Ultsch M,Eigenbrot C,McVean G,Fugger L
25-0049 was used in Flow cytometry/Cell sorting to reveal a protective homozygous effect that defined a signalling optimum between autoimmunity and immunodeficiency and identified TYK2 as a potential drug target for autoimmune disorders.
Wed Nov 02 00:00:00 EDT 2016
Remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions.
Proceedings of the National Academy of Sciences of the United States of America
Jönsson P,Southcombe JH,Santos AM,Huo J,Fernandes RA,McColl J,Lever M,Evans EJ,Hudson A,Chang VT,Hanke T,Godkin A,Dunne PD,Horrocks MH,Palayret M,Screaton GR,Petersen J,Rossjohn J,Fugger L,Dushek O,Xu XN,Davis SJ,Klenerman D
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Tue May 17 00:00:00 EDT 2016
Role of podoplanin in the high interleukin-17A secretion resulting from interactions between activated lymphocytes and psoriatic skin-derived mesenchymal cells.
Clinical and experimental immunology
Noack M,Ndongo-Thiam N,Miossec P
25-0049-42 was used in Flow cytometry/Cell sorting to study the interactions of skin-derived fibroblasts with peripheral blood mononuclear cells (PBMC) with a focus on the Th17 pathway and to identify a mechanism which leads to a high interleukin (IL)-17 secretion.
Sat Oct 01 00:00:00 EDT 2016
Interaction among activated lymphocytes and mesenchymal cells through podoplanin is critical for a high IL-17 secretion.
Arthritis research & therapy
Noack M,Ndongo-Thiam N,Miossec P
25-0049 was used in Flow cytometry/Cell sorting to study interactions between synoviocytes from rheumatoid arthritis patients and peripheral blood mononuclear cells, and their effect on the Th17 pathway during chronic inflammation.
Thu Jun 23 00:00:00 EDT 2016
CD28 family of receptors on T cells in chronic HBV infection: Expression characteristics, clinical significance and correlations with PD-1 blockade.
Molecular medicine reports
Tang ZS,Hao YH,Zhang EJ,Xu CL,Zhou Y,Zheng X,Yang DL
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Equilibrium of Treg/Th17 cells of peripheral blood in syphilitic patients with sero-resistance.
Experimental and therapeutic medicine
Zhao J,Ma J,Zhang X,Li Q,Yang X
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Wed Jun 01 00:00:00 EDT 2016
Tuning of AKT-pathway by Nef and its blockade by protease inhibitors results in limited recovery in latently HIV infected T-cell line.
Scientific reports
Kumar A,Abbas W,Colin L,Khan KA,Bouchat S,Varin A,Larbi A,Gatot JS,Kabeya K,Vanhulle C,Delacourt N,Pasquereau S,Coquard L,Borch A,König R,Clumeck N,De Wit S,Rohr O,Rouzioux C,Fulop T,Van Lint C,Herbein G
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Thu Apr 14 00:00:00 EDT 2016
Lack of T Cell Response to iPSC-Derived Retinal Pigment Epithelial Cells from HLA Homozygous Donors.
Stem cell reports
Sugita S,Iwasaki Y,Makabe K,Kimura T,Futagami T,Suegami S,Takahashi M
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Tue Oct 11 00:00:00 EDT 2016
Cyclosporine A immunosuppression drives catastrophic squamous cell carcinoma through IL-22.
JCI insight
Abikhair M,Mitsui H,Yanofsky V,Roudiani N,Ovits C,Bryan T,Oberyszyn TM,Tober KL,Gonzalez J,Krueger JG,Felsen D,Carucci JA
25-0049 was used in Flow cytometry/Cell sorting to study how blockade of the IL-22 axis may be developed as a viable therapeutic option for catastrophic SCC.
Thu Jun 02 00:00:00 EDT 2016
Atezolizumab in combination with bevacizumab enhances antigen-specific T-cell migration in metastatic renal cell carcinoma.
Nature communications
Wallin JJ,Bendell JC,Funke R,Sznol M,Korski K,Jones S,Hernandez G,Mier J,He X,Hodi FS,Denker M,Leveque V,Cañamero M,Babitski G,Koeppen H,Ziai J,Sharma N,Gaire F,Chen DS,Waterkamp D,Hegde PS,McDermott DF
25-0049 was used in Flow cytometry/Cell sorting to suggest that the anti-VEGF and anti-PD-L1 combination improves antigen-specific T-cell migration.
Tue Aug 30 00:00:00 EDT 2016
Antitumor immunity triggered by melphalan is potentiated by melanoma cell surface-associated calreticulin.
Cancer research
Dudek-Perić AM,Ferreira GB,Muchowicz A,Wouters J,Prada N,Martin S,Kiviluoto S,Winiarska M,Boon L,Mathieu C,van den Oord J,Stas M,Gougeon ML,Golab J,Garg AD,Agostinis P
25-0049 was used in Flow cytometry/Cell sorting to illustrate how melphalan triggers inflammatory cell death that can be leveraged by immunomodulators.
Wed Apr 15 00:00:00 EDT 2015
Liposomal Glutathione Supplementation Restores TH1 Cytokine Response to Mycobacterium tuberculosis Infection in HIV-Infected Individuals.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Ly J,Lagman M,Saing T,Singh MK,Tudela EV,Morris D,Anderson J,Daliva J,Ochoa C,Patel N,Pearce D,Venketaraman V
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2015
Distinct patterns of intratumoral immune cell infiltrates in patients with HPV-associated compared to non-virally induced head and neck squamous cell carcinoma.
Oncoimmunology
Partlová S,Bouček J,Kloudová K,Lukešová E,Zábrodský M,Grega M,Fučíková J,Truxová I,Tachezy R,Špíšek R,Fialová A
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Thu Jan 01 00:00:00 EST 2015
dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis.
Nature communications
Lim S,Kim WJ,Kim YH,Lee S,Koo JH,Lee JA,Yoon H,Kim DH,Park HJ,Kim HM,Lee HG,Yun Kim J,Lee JU,Hun Shin J,Kyun Kim L,Doh J,Kim H,Lee SK,Bothwell ALM,Suh M,Choi JM
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Tue Sep 15 00:00:00 EDT 2015
Investigating the causes for decreased levels of glutathione in individuals with type II diabetes.
PloS one
Lagman M,Ly J,Saing T,Kaur Singh M,Vera Tudela E,Morris D,Chi PT,Ochoa C,Sathananthan A,Venketaraman V
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Wed Dec 30 00:00:00 EST 2015
NF-κB, p38 MAPK, ERK1/2, mTOR, STAT3 and increased glycolysis regulate stability of paricalcitol/dexamethasone-generated tolerogenic dendritic cells in the inflammatory environment.
Oncotarget
Dáňová K,Klapetková A,Kayserová J,Šedivá A,Špíšek R,Jelínková LP
25-0049 was used in Flow cytometry/Cell sorting to investigate the signalling pathways regulating the properties of tolerogenic dendritic cells in the inflammatory environment.
Wed Jun 10 00:00:00 EDT 2015
Improved Natural Killer cell activity and retained anti-tumor CD8(+) T cell responses contribute to the induction of a pathological complete response in HER2-positive breast cancer patients undergoing neoadjuvant chemotherapy.
Journal of translational medicine
Muraro E,Comaro E,Talamini R,Turchet E,Miolo G,Scalone S,Militello L,Lombardi D,Spazzapan S,Perin T,Massarut S,Crivellari D,Dolcetti R,Martorelli D
25-0049 was used in Flow cytometry/Cell sorting to indicate that maintenance of functional T cell responses against selected antigens and improvement of NK cell proficiency during NC are probably critical requirements for pCR induction.
Sat Jun 27 00:00:00 EDT 2015
Immune response to JC virus T antigen in patients with and without colorectal neoplasia.
Gut microbes
Butcher LD,Garcia M,Arnold M,Ueno H,Goel A,Boland CR
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Tue Jul 01 00:00:00 EDT 2014
OMIP-022: Comprehensive assessment of antigen-specific human T-cell functionality and memory.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Graves AJ,Padilla MG,Hokey DA
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Tue Jul 01 00:00:00 EDT 2014
Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3⁺ regulatory T cells.
Nature immunology
Pierson W,Cauwe B,Policheni A,Schlenner SM,Franckaert D,Berges J,Humblet-Baron S,Schönefeldt S,Herold MJ,Hildeman D,Strasser A,Bouillet P,Lu LF,Matthys P,Freitas AA,Luther RJ,Weaver CT,Dooley J,Gray DH,Liston A
25-0049 was used in Flow cytometry/Cell sorting to study the regulation of the Foxp3+ T cell pool by proliferation and apoptosis, and specifically the role of antiapoptoic Mcl-1 in T cell survival.
Sun Sep 01 00:00:00 EDT 2013
ROS-induced autophagy in cancer cells assists in evasion from determinants of immunogenic cell death.
Autophagy
Garg AD,Dudek AM,Ferreira GB,Verfaillie T,Vandenabeele P,Krysko DV,Mathieu C,Agostinis P
25-0049 was used in Flow cytometry/Cell sorting to unravel a role for ROS-induced autophagy in weakening functional interaction between dying cancer cells and the immune system.
Sun Sep 01 00:00:00 EDT 2013
Human regulatory T cells kill tumor cells through granzyme-dependent cytotoxicity upon retargeting with a bispecific antibody.
Cancer immunology research
Choi BD,Gedeon PC,Herndon JE,Archer GE,Reap EA,Sanchez-Perez L,Mitchell DA,Bigner DD,Sampson JH
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Sun Sep 01 00:00:00 EDT 2013
Neuropilin-1 expression characterizes T follicular helper (Tfh) cells activated during B cell differentiation in human secondary lymphoid organs.
PloS one
Renand A,Milpied P,Rossignol J,Bruneau J,Lemonnier F,Dussiot M,Coulon S,Hermine O
25-0049 was used in Flow cytometry/Cell sorting to characterise Nrp1-expressing T cells in human secondary lymphoid organs.
Mon Feb 23 00:00:00 EST 2015
Increased frequencies of Th22 cells as well as Th17 cells in the peripheral blood of patients with ankylosing spondylitis and rheumatoid arthritis.
PloS one
Zhang L,Li YG,Li YH,Qi L,Liu XG,Yuan CZ,Hu NW,Ma DX,Li ZF,Yang Q,Li W,Li JM
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Fri Jul 27 00:00:00 EDT 2012
ChIP-on-chip analysis identifies IL-22 as direct target gene of ectopically expressed FOXP3 transcription factor in human T cells.
BMC genomics
Jeron A,Hansen W,Ewert F,Buer J,Geffers R,Bruder D
25-0049 was used in Flow cytometry/Cell sorting to analyse human FOXP3 ectopically expressed in a Jurkat T-cell line under resting and mitogen-stimulated conditions to identify its direct target genes.
Mon Dec 17 00:00:00 EST 2012
Upregulation of programmed death-1 on T cells and programmed death ligand-1 on monocytes in septic shock patients.
Critical care (London, England)
Zhang Y,Li J,Lou J,Zhou Y,Bo L,Zhu J,Zhu K,Wan X,Cai Z,Deng X
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Wed Dec 07 00:00:00 EST 2011
Uncoupling of proliferation and cytokines from suppression within the CD4+CD25+Foxp3+ T-cell compartment in the 1st year of human type 1 diabetes.
Diabetes
Hughson A,Bromberg I,Johnson B,Quataert S,Jospe N,Fowell DJ
25-0049 was used in Flow cytometry/Cell sorting to determine the relative proportions of effector and regulatory T cells in the CD4+CD25+Foxp3+ T-cell compartment in varying type 1 diabetes disease states.
Mon Aug 01 00:00:00 EDT 2011
A different immunologic profile characterizes patients with HER-2-overexpressing and HER-2-negative locally advanced breast cancer: implications for immune-based therapies.
Breast cancer research : BCR
Muraro E,Martorelli D,Turchet E,Miolo G,Scalone S,Comaro E,Talamini R,Mastorci K,Lombardi D,Perin T,Carbone A,Veronesi A,Crivellari D,Dolcetti R
25-0049 was used in Flow cytometry/Cell sorting to demonstrate that patients with HER2-overexpressing locally advanced breast cancer show more limited tumour-related immune suppression than HER2- patients.
Mon Jun 25 00:00:00 EDT 2012
Modulation of CD4+ T lymphocyte lineage outcomes with targeted, nanoparticle-mediated cytokine delivery.
Molecular pharmaceutics
Park J,Gao W,Whiston R,Strom TB,Metcalfe S,Fahmy TM
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Mon Feb 07 00:00:00 EST 2011
Differential expression of CD300a/c on human TH1 and TH17 cells.
BMC immunology
Simhadri VR,Mariano JL,Zhou Q,DeBell KE,Borrego F
25-0049 was used in Flow cytometry/Cell sorting to conclude that the CD300a/c receptors are differentially expressed on human TH1 and TH17 cells, and that their ligation is capable of modulating TCR mediated signals.
Wed Nov 02 00:00:00 EDT 2011
Human basophils express amphiregulin in response to T cell-derived IL-3.
The Journal of allergy and clinical immunology
Qi Y,Operario DJ,Oberholzer CM,Kobie JJ,Looney RJ,Georas SN,Mosmann TR
25-0049 was used in Flow cytometry/Cell sorting to identify the human peripheral blood cell population expressing amphiregulin, showing that human basophils express amphiregulin in response to T cell-derived IL-3.
Wed Dec 01 00:00:00 EST 2010
Human Th1 cells that express CD300a are polyfunctional and after stimulation up-regulate the T-box transcription factor eomesodermin.
PloS one
Narayanan S,Silva R,Peruzzi G,Alvarez Y,Simhadri VR,Debell K,Coligan JE,Borrego F
25-0049 was used in Flow cytometry/Cell sorting to investigate a subset within the CD4 T cell population defined by expression of the immunomodulatory receptor CD300a.
Thu May 13 00:00:00 EDT 2010
Sepsis-induced human lymphocyte apoptosis and cytokine production in "humanized" mice.
Journal of leukocyte biology
Unsinger J,McDonough JS,Shultz LD,Ferguson TA,Hotchkiss RS
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Sat Aug 01 00:00:00 EDT 2009
Fc receptor-like 3 protein expressed on IL-2 nonresponsive subset of human regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950)
Nagata S,Ise T,Pastan I
25-0049 was used in Flow cytometry/Cell sorting to study the effects of Foxp3 and IL-2 on FCRL3-/+ nTreg cell subsets.
Mon Jun 15 00:00:00 EDT 2009
B cells and monocytes from patients with active multiple sclerosis exhibit increased surface expression of both HERV-H Env and HERV-W Env, accompanied by increased seroreactivity.
Retrovirology
Brudek T,Christensen T,Aagaard L,Petersen T,Hansen HJ,Møller-Larsen A
Published figure using CD4 monoclonal antibody (Product # 25-0049-42) in Flow Cytometry
Mon Nov 16 00:00:00 EST 2009
