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            • Primary Antibodies ›
            • CD44v4 Antibodies

            NeoBiotechnologies

            CD44v4 (Marker of Tumor Metastasis) Polyclonal Antibody

            View all (13) CD44v4 antibodies
            Datasheet
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            Datasheet
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            Cite CD44v4 (Marker of Tumor Metastasis) Polyclonal Antibody

            • Antibody Testing Data (1)
            Application
            CD44v4 (Marker of Tumor Metastasis) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Group 53 Created with Sketch.

            FIGURE: 1 / 1

            CD44v4 (Marker of Tumor Metastasis) Antibody (960-RBP15-P0) in IHC (P)

            Formalin-fixed, paraffin-embedded human Cervical Squamous Cell Carcinoma stained with CD44v4 Rabbit Polyclonal Antibody.
            View Product

            CD44v4 (Marker of Tumor Metastasis) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

            Product Details

            960-RBP15-P0

            Applications
            Tested Dilution
            Publications

            Immunohistochemistry (Paraffin) (IHC (P))

            Assay-dependent
            -

            Immunohistochemistry (PFA fixed) (IHC (PFA))

            1-2 µg/mL
            -
            Product Specifications

            Species Reactivity

            Human

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Recombinant fragment corresponding to the v4 domain of human CD44

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            200 µg/mL

            Purification

            Protein A

            Storage buffer

            PBS, pH 7.4, with 0.05% BSA

            Contains

            0.05% sodium azide

            Storage conditions

            4°C, do not freeze

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            Target Information

            CD44 cell surface antigen is a 100kDa glycoprotein widely expressed on human leucocytes, white matter of the brain and by some epithelial cells of the intestine and breast. Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues. CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion and migration. CD44 also participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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            Cite this product

            Bioinformatics

            Protein Aliases: AL133330.1; CD44; CD44 antigen; CD44 splice variant; CD44 var; CD44 variant; CD44v4; CDw44; cell surface glycoprotein CD44; chondroitin sulfate proteoglycan 8; ECMR-III; ECMRIII; Epican; Extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; H-CAM v4; hematopoietic cell E- and L-selectin ligand; Heparan sulfate proteoglycan; Hermes antigen; homing function and Indian blood group system; HUTCH-I; HUTCHI; Hyaluronate receptor; PGP I; PGP-1; PGP-I; Phagocytic glycoprotein 1; Phagocytic glycoprotein I; RP23-203N8.3; soluble CD44

            View more View less

            Gene Aliases: CD44; CDW44; CSPG8; ECMR-III; HCELL; HUTCH-I; IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1

            View more View less

            UniProt ID: (Human) P16070

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            Entrez Gene ID: (Human) 960

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            Function(s)

            cytokine receptor activity protein binding collagen binding hyaluronic acid binding transmembrane signal receptor

            Process(es)

            cell-matrix adhesion single organismal cell-cell adhesion extracellular matrix disassembly extracellular matrix organization hyaluronan catabolic process positive regulation of peptidyl-serine phosphorylation positive regulation of heterotypic cell-cell adhesion negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of DNA damage response, signal transduction by p53 class mediator cellular response to fibroblast growth factor stimulus positive regulation of peptidyl-tyrosine phosphorylation leukocyte migration cartilage development interferon-gamma-mediated signaling pathway positive regulation of ERK1 and ERK2 cascade monocyte aggregation positive regulation of monocyte aggregation negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
            It has to be done as per old AB suggested Products section.
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            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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