Product References
The astrocyte-produced growth factor HB-EGF limits autoimmune CNS pathology.
Nature immunology
Linnerbauer M,Lößlein L,Vandrey O,Peter A,Han Y,Tsaktanis T,Wogram E,Needhamsen M,Kular L,Nagel L,Zissler J,Andert M,Meszaros L,Hanspach J,Zuber F,Naumann UJ,Diebold M,Wheeler MA,Beyer T,Nirschl L,Cirac A,Laun FB,Günther C,Winkler J,Bäuerle T,Jagodic M,Hemmer B,Prinz M,Quintana FJ,Rothhammer V
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Mar 01 00:00:00 UTC 2024
Osimertinib Covalently Binds to CD34 and Eliminates Myeloid Leukemia Stem/Progenitor Cells.
Cancer research
Xia L,Liu JY,Yang MY,Zhang XH,Jiang Y,Yin QQ,Luo CH,Liu HC,Kang ZJ,Zhang CT,Gao BB,Zhou AW,Cai HY,Waller EK,Yan JS,Lu Y
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Feb 01 00:00:00 UTC 2024
Spleen-targeted neoantigen DNA vaccine for personalized immunotherapy of hepatocellular carcinoma.
EMBO molecular medicine
Wu M,Luo Z,Cai Z,Mao Q,Li Z,Li H,Zhang C,Zhang Y,Zhong A,Wu L,Liu X
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Wed Oct 11 00:00:00 UTC 2023
VEGF-A in serum protects against memory impairment in APP/PS1 transgenic mice by blocking neutrophil infiltration.
Molecular psychiatry
Qi F,Zuo Z,Hu K,Wang R,Wu T,Liu H,Tang J,Wang Q,Xie Y,Tan L,Yang Y,Zhang X,Zheng J,Xu J,Yao Z,Wang S,Wu LJ,Guo K
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Sun Oct 01 00:00:00 UTC 2023
Fibroblastic reticular cells in lymph node potentiate white adipose tissue beiging through neuro-immune crosstalk in male mice.
Nature communications
Cheong LY,Wang B,Wang Q,Jin L,Kwok KHM,Wu X,Shu L,Lin H,Chung SK,Cheng KKY,Hoo RLC,Xu A
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Mar 03 00:00:00 UTC 2023
Old age promotes retinal fibrosis in choroidal neovascularization through circulating fibrocytes and profibrotic macrophages.
Journal of neuroinflammation
Yi C,Liu J,Deng W,Luo C,Qi J,Chen M,Xu H
14-0451-82 was used in Immunohistochemistry-immunofluorescence to investigate the effect of ageing on subretinal fibrosis secondary to choroidal neovascularization and the mechanism of action.
Thu Feb 23 00:00:00 UTC 2023
Macrophagic AMPKα1 orchestrates regenerative inflammation induced by glucocorticoids.
EMBO reports
Caratti G,Desgeorges T,Juban G,Stifel U,Fessard A,Koenen M,Caratti B,Théret M,Skurk C,Chazaud B,Tuckermann JP,Mounier R
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Feb 06 00:00:00 UTC 2023
Tumor-suppressive role of the musculoaponeurotic fibrosarcoma gene in colorectal cancer.
iScience
Itakura H,Hata T,Okuzaki D,Takeda K,Iso K,Qian Y,Morimoto Y,Adachi T,Hirose H,Yokoyama Y,Ogino T,Miyoshi N,Takahashi H,Uemura M,Mizushima T,Hinoi T,Mori M,Doki Y,Eguchi H,Yamamoto H
14-0451-82 was used in Immunohistochemistry to investigate whether these microRNAs inhibit colorectal tumorigenesis in CPC;Apc mice, which are prone to colon and rectal polyps.
Fri Apr 21 00:00:00 UTC 2023
Targeting myocardial equilibrative nucleoside transporter ENT1 provides cardioprotection by enhancing myeloid Adora2b signaling.
JCI insight
Ruan W,Li J,Choi S,Ma X,Liang Y,Nair R,Yuan X,Mills TW,Eltzschig HK
14-0451-82 was used in Flow cytometry/Cell sorting to reveal a previously unrecognized role for myocyte-specific ENT1 in cardioprotection by enhancing myeloid-dependent Adora2b signaling during reperfusion.
Thu Jun 08 00:00:00 UTC 2023
Topical Diacerein Decreases Skin and Splenic CD11c+ Dendritic Cells in Psoriasis.
International journal of molecular sciences
Brunner SM,Ramspacher A,Rieser C,Leitner J,Heil H,Ablinger M,Tevini J,Wimmer M,Koller A,Piñón Hofbauer J,Felder TK,Bauer JW,Kofler B,Lang R,Wally V
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Feb 21 00:00:00 UTC 2023
Toll-like Receptor Signaling-deficient Cells Enhance Antitumor Activity of Cell-based Immunotherapy by Increasing Tumor Homing.
Cancer research communications
Morales-Molina A,Rodriguez-Milla MÁ,Gambera S,Cejalvo T,de Andrés B,Gaspar ML,García-Castro J
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Wed Mar 01 00:00:00 UTC 2023
Myc-dependent dedifferentiation of Gata6+ epidermal cells resembles reversal of terminal differentiation.
Nature cell biology
Bernabé-Rubio M,Ali S,Bhosale PG,Goss G,Mobasseri SA,Tapia-Rojo R,Zhu T,Hiratsuka T,Battilocchi M,Tomás IM,Ganier C,Garcia-Manyes S,Watt FM
14-0451-82 was used in Immunohistochemistry to elucidate the molecular basis of epidermal dedifferentiation, which may be generally applicable to adult tissues.
Sun Oct 01 00:00:00 UTC 2023
siRNA-Mediated MELK Knockdown Induces Accelerated Wound Healing with Increased Collagen Deposition.
International journal of molecular sciences
Szymanski L,Lewicki S,Markiewicz T,Cierniak S,Tassan JP,Kubiak JZ
14-0451-82 was used in Immunocytochemistry to evaluate the potential of MELK silencing to accelerate wound healing.
Tue Jan 10 00:00:00 UTC 2023
BRCA1 deficiency in mature CD8+ T lymphocytes impairs antitumor immunity.
Journal for immunotherapy of cancer
Wu B,Qi L,Chiang HC,Pan H,Zhang X,Greenbaum A,Stark E,Wang LJ,Chen Y,Haddad BR,Clagett D,Isaacs C,Elledge R,Horvath A,Hu Y,Li R
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Wed Feb 01 00:00:00 UTC 2023
CD11c+ microglia promote white matter repair after ischemic stroke.
Cell death & disease
Jia J,Zheng L,Ye L,Chen J,Shu S,Xu S,Bao X,Xia S,Liu R,Xu Y,Zhang M
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Feb 24 00:00:00 UTC 2023
Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zhang Y,Liu T,Deng Z,Fang W,Zhang X,Zhang S,Wang M,Luo S,Meng Z,Liu J,Sukhova GK,Li D,McKenzie ANJ,Libby P,Shi GP,Guo J
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Wed Mar 01 00:00:00 UTC 2023
Abnormal adipogenic signaling in the bone marrow mesenchymal stem cells contributes to supportive microenvironment for leukemia development.
Cell communication and signaling : CCS
Sabbah R,Saadi S,Shahar-Gabay T,Gerassy S,Yehudai-Resheff S,Zuckerman T
14-0451-82 was used in Immunohistochemistry to show that AML-induced adipocytes were the dominant component of the tumor microenvironment, providing preferential support to leukemia cell survival and proliferation.
Tue Oct 10 00:00:00 UTC 2023
The polarization of microglia and infiltrated macrophages in the injured mice spinal cords: a dynamic analysis.
PeerJ
Li JL,Fu GQ,Wang YY,Bian MM,Xu YM,Zhang L,Chen YQ,Zhang N,Ding SQ,Wang R,Fang R,Tang J,Hu JG,Lü HZ
14-0451-82 was used in Immunohistochemistry-immunofluorescence to study if M1 cells in injured spinal cords were mainly derived from MG rather than infiltrating Mø.
Tue Feb 28 00:00:00 UTC 2023
Senolytic elimination of Cox2-expressing senescent cells inhibits the growth of premalignant pancreatic lesions.
Gut
Kolodkin-Gal D,Roitman L,Ovadya Y,Azazmeh N,Assouline B,Schlesinger Y,Kalifa R,Horwitz S,Khalatnik Y,Hochner-Ger A,Imam A,Demma JA,Winter E,Benyamini H,Elgavish S,Khatib AA,Meir K,Atlan K,Pikarsky E,Parnas O,Dor Y,Zamir G,Ben-Porath I,Krizhanovsky V
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Tue Feb 01 00:00:00 UTC 2022
The ZIP8/SIRT1 axis regulates alveolar progenitor cell renewal in aging and idiopathic pulmonary fibrosis.
The Journal of clinical investigation
Liang J,Huang G,Liu X,Taghavifar F,Liu N,Wang Y,Deng N,Yao C,Xie T,Kulur V,Dai K,Burman A,Rowan SC,Weigt SS,Belperio J,Stripp B,Parks WC,Jiang D,Noble PW
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Wed Jun 01 00:00:00 UTC 2022
Interleukin-10 genetically modified clinical-grade mesenchymal stromal cells markedly reinforced functional recovery after spinal cord injury via directing alternative activation of macrophages.
Cellular & molecular biology letters
Gao T,Huang F,Wang W,Xie Y,Wang B
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Mar 17 00:00:00 UTC 2022
BEX1 is a critical determinant of viral myocarditis.
PLoS pathogens
Martens CR,Dorn LE,Kenney AD,Bansal SS,Yount JS,Accornero F
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Feb 01 00:00:00 UTC 2022
Trappc9 Deficiency Impairs the Plasticity of Stem Cells.
International journal of molecular sciences
Usman M,Li Y,Ke Y,Chhetri G,Islam MA,Wang Z,Li X
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunocytochemistry
Thu Apr 28 00:00:00 UTC 2022
GPR92 activation in islet macrophages controls β cell function in a diet-induced obesity model.
The Journal of clinical investigation
de Souza CO,Paschoal VA,Sun X,Vishvanath L,Zhang Q,Shao M,Onodera T,Chen S,Joffin N,Bueno LM,Gupta RK,Oh DY
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Nov 01 00:00:00 UTC 2022
Mineralocorticoid receptor antagonists and glucocorticoids differentially affect skeletal muscle inflammation and pathology in muscular dystrophy.
JCI insight
Howard ZM,Gomatam CK,Rabolli CP,Lowe J,Piepho AB,Bansal SS,Accornero F,Rafael-Fortney JA
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Oct 10 00:00:00 UTC 2022
Comparative analysis of thoracic and abdominal aortic aneurysms across the segment and species at the single-cell level.
Frontiers in pharmacology
Wu H,Xie C,Wang R,Cheng J,Xu Q,Zhao H
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Feb 02 00:00:00 UTC 2023
Microglial angiotensin type 2 receptors mediate sex-specific expression of inflammatory cytokines independently of circulating estrogen.
Glia
Garrido-Gil P,Pedrosa MA,Garcia-Garrote M,Pequeño-Valtierra A,Rodríguez-Castro J,García-Souto D,Rodríguez-Pérez AI,Labandeira-Garcia JL
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Dec 01 00:00:00 UTC 2022
Hematopoietic-Mesenchymal Signals Regulate the Properties of Mesenchymal Stem Cells.
International journal of molecular sciences
Kanazawa S,Okada H,Riu D,Mabuchi Y,Akazawa C,Iwata J,Hoshi K,Hikita A
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Jul 26 00:00:00 UTC 2022
Identification of CD157-Positive Vascular Endothelial Stem Cells in Mouse Retinal and Choroidal Vessels: Fluorescence-Activated Cell Sorting Analysis.
Investigative ophthalmology & visual science
Wakabayashi T,Naito H,Iba T,Nishida K,Takakura N
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Apr 01 00:00:00 UTC 2022
Gene-selective transcription promotes the inhibition of tissue reparative macrophages by TNF.
Life science alliance
Dichtl S,Sanin DE,Koss CK,Willenborg S,Petzold A,Tanzer MC,Dahl A,Kabat AM,Lindenthal L,Zeitler L,Satzinger S,Strasser A,Mann M,Roers A,Eming SA,El Kasmi KC,Pearce EJ,Murray PJ
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Apr 01 00:00:00 UTC 2022
Intranasal delivery of a small-molecule ErbB inhibitor promotes recovery from acute and late-stage CNS inflammation.
JCI insight
Linnerbauer M,Lößlein L,Vandrey O,Tsaktanis T,Beer A,Naumann UJ,Panier F,Beyer T,Nirschl L,Kuramatsu JB,Winkler J,Quintana FJ,Rothhammer V
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Apr 08 00:00:00 UTC 2022
A Point Mutation R122C in RUNX3 Promotes the Expansion of Isthmus Stem Cells and Inhibits Their Differentiation in the Stomach.
Cellular and molecular gastroenterology and hepatology
Douchi D,Yamamura A,Matsuo J,Lee JW,Nuttonmanit N,Melissa Lim YH,Suda K,Shimura M,Chen S,Pang S,Kohu K,Kaneko M,Kiyonari H,Kaneda A,Yoshida H,Taniuchi I,Osato M,Yang H,Unno M,Bok-Yan So J,Yeoh KG,Chuang LSH,Bae SC,Ito Y
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Mon Apr 18 00:00:00 UTC 2022
Tumor collection/processing under physioxia uncovers highly relevant signaling networks and drug sensitivity.
Science advances
Kumar B,Adebayo AK,Prasad M,Capitano ML,Wang R,Bhat-Nakshatri P,Anjanappa M,Simpson E,Chen D,Liu Y,Schilder JM,Colter AB,Maguire C,Temm CJ,Sandusky G,Doud EH,Wijeratne AB,Mosley AL,Broxmeyer HE,Nakshatri H
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Jan 14 00:00:00 UTC 2022
The RNA-binding protein IMP2 drives a stromal-Th17 cell circuit in autoimmune neuroinflammation.
JCI insight
Bechara R,Amatya N,Majumder S,Zhou C,Li Y,Liu Q,McGeachy MJ,Gaffen SL
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Feb 08 00:00:00 UTC 2022
The RNA-binding protein IMP2 drives a stromal-Th17 cell circuit in autoimmune neuroinflammation.
JCI insight
Bechara R,Amatya N,Majumder S,Zhou C,Li Y,Liu Q,McGeachy MJ,Gaffen SL
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Feb 08 00:00:00 UTC 2022
Candida tropicalis Infection Modulates the Gut Microbiome and Confers Enhanced Susceptibility to Colitis in Mice.
Cellular and molecular gastroenterology and hepatology
Di Martino L,De Salvo C,Buela KA,Hager C,Ghannoum M,Osme A,Buttò L,Bamias G,Pizarro TT,Cominelli F
14-0451-82 was used in Flow Cytometry to determine the effects and mechanisms of action of Candida tropicalis on intestinal inflammation and injury in mouse models.
Mon Apr 04 00:00:00 UTC 2022
Induction of Gastric Cancer by Successive Oncogenic Activation in the Corpus.
Gastroenterology
Douchi D,Yamamura A,Matsuo J,Melissa Lim YH,Nuttonmanit N,Shimura M,Suda K,Chen S,Pang S,Kohu K,Abe T,Shioi G,Kim G,Shabbir A,Srivastava S,Unno M,Bok-Yan So J,Teh M,Yeoh KG,Chuang LSH,Ito Y
14-0451-82 was used in Immunohistochemistry to investigate whether pepsinogen C (PGC) transcript-expressing cells represent the cellular origin of metaplasia and cancer using a novel Pgc-specific CreERT2 recombinase mouse model.
Wed Dec 01 00:00:00 UTC 2021
Induction of alarmin S100A8/A9 mediates activation of aberrant neutrophils in the pathogenesis of COVID-19.
Cell host & microbe
Guo Q,Zhao Y,Li J,Liu J,Yang X,Guo X,Kuang M,Xia H,Zhang Z,Cao L,Luo Y,Bao L,Wang X,Wei X,Deng W,Wang N,Chen L,Chen J,Zhu H,Gao R,Qin C,Wang X,You F
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Wed Feb 10 00:00:00 UTC 2021
Stage-specific action of Runx1 and GATA3 controls silencing of PU.1 expression in mouse pro-T cells.
The Journal of experimental medicine
Hosokawa H,Koizumi M,Masuhara K,Romero-Wolf M,Tanaka T,Nakayama T,Rothenberg EV
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Aug 02 00:00:00 UTC 2021
Hepatic Mitochondrial SAB Deletion or Knockdown Alleviates Diet-Induced Metabolic Syndrome, Steatohepatitis, and Hepatic Fibrosis.
Hepatology (Baltimore, Md.)
Win S,Min RWM,Zhang J,Kanel G,Wanken B,Chen Y,Li M,Wang Y,Suzuki A,Aung FWM,Murray SF,Aghajan M,Than TA,Kaplowitz N
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Wed Dec 01 00:00:00 UTC 2021
Uptake and trafficking of different sized PLGA nanoparticles by dendritic cells in imiquimod-induced psoriasis-like mice model.
Acta pharmaceutica Sinica. B
Lin Z,Xi L,Chen S,Tao J,Wang Y,Chen X,Li P,Wang Z,Zheng Y
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Apr 01 00:00:00 UTC 2021
Mapping the origin and fate of myeloid cells in distinct compartments of the eye by single-cell profiling.
The EMBO journal
Wieghofer P,Hagemeyer N,Sankowski R,Schlecht A,Staszewski O,Amann L,Gruber M,Koch J,Hausmann A,Zhang P,Boneva S,Masuda T,Hilgendorf I,Goldmann T,Böttcher C,Priller J,Rossi FM,Lange C,Prinz M
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Mar 15 00:00:00 UTC 2021
Ablation of lysozyme M-positive cells prevents aircraft noise-induced vascular damage without improving cerebral side effects.
Basic research in cardiology
Frenis K,Helmstädter J,Ruan Y,Schramm E,Kalinovic S,Kröller-Schön S,Bayo Jimenez MT,Hahad O,Oelze M,Jiang S,Wenzel P,Sommer CJ,Frauenknecht KBM,Waisman A,Gericke A,Daiber A,Münzel T,Steven S
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Apr 30 00:00:00 UTC 2021
Photoreceptor protection by mesenchymal stem cell transplantation identifies exosomal MiR-21 as a therapeutic for retinal degeneration.
Cell death and differentiation
Deng CL,Hu CB,Ling ST,Zhao N,Bao LH,Zhou F,Xiong YC,Chen T,Sui BD,Yu XR,Hu CH
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Mar 01 00:00:00 UTC 2021
Loss of p53 in mesenchymal stem cells promotes alteration of bone remodeling through negative regulation of osteoprotegerin.
Cell death and differentiation
Velletri T,Huang Y,Wang Y,Li Q,Hu M,Xie N,Yang Q,Chen X,Chen Q,Shou P,Gan Y,Candi E,Annicchiarico-Petruzzelli M,Agostini M,Yang H,Melino G,Shi Y,Wang Y
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Jan 01 00:00:00 UTC 2021
Decreased antiviral immune response within the central nervous system of aged mice is associated with increased lethality of West Nile virus encephalitis.
Aging cell
Funk KE,Arutyunov AD,Desai P,White JP,Soung AL,Rosen SF,Diamond MS,Klein RS
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Sun Aug 01 00:00:00 UTC 2021
Deletion of mTOR in liver epithelial cells enhances hepatic metastasis of colon cancer.
The Journal of pathology
Jiao L,Eickhoff R,Egners A,Jumpertz S,Roth J,Erdem M,Kroh A,Duimel H,López-Iglesias C,Caro P,Heij LR,Schmeding M,Meierhofer D,Neumann UP,Cramer T
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Mon Nov 01 00:00:00 UTC 2021
Anti-adipogenic signals at the onset of obesity-related inflammation in white adipose tissue.
Cellular and molecular life sciences : CMLS
Caputo T,Tran VDT,Bararpour N,Winkler C,Aguileta G,Trang KB,Giordano Attianese GMP,Wilson A,Thomas A,Pagni M,Guex N,Desvergne B,Gilardi F
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Jan 01 00:00:00 UTC 2021
RANKL from bone marrow adipose lineage cells promotes osteoclast formation and bone loss.
EMBO reports
Hu Y,Li X,Zhi X,Cong W,Huang B,Chen H,Wang Y,Li Y,Wang L,Fang C,Guo J,Liu Y,Cui J,Cao L,Weng W,Zhou Q,Wang S,Chen X,Su J
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Jul 05 00:00:00 UTC 2021
Macrophage polarization by MSC-derived CXCL12 determines tumor growth.
Cellular & molecular biology letters
Babazadeh S,Nassiri SM,Siavashi V,Sahlabadi M,Hajinasrollah M,Zamani-Ahmadmahmudi M
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Sat Jun 26 00:00:00 UTC 2021
The effects of postmortem delay on mouse and human microglia gene expression.
Glia
Heng Y,Dubbelaar ML,Marie SKN,Boddeke EWGM,Eggen BJL
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Apr 01 00:00:00 UTC 2021
Intrinsic DNA damage repair deficiency results in progressive microglia loss and replacement.
Glia
Zhang X,Heng Y,Kooistra SM,van Weering HRJ,Brummer ML,Gerrits E,Wesseling EM,Brouwer N,Nijboer TW,Dubbelaar ML,Boddeke EWGM,Eggen BJL
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Mar 01 00:00:00 UTC 2021
Intercellular Interactions of an Adipogenic CXCL12-Expressing Stromal Cell Subset in Murine Bone Marrow.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Matsushita Y,Chu AKY,Ono W,Welch JD,Ono N
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunocytochemistry
Tue Jun 01 00:00:00 UTC 2021
Intercellular Interactions of an Adipogenic CXCL12-Expressing Stromal Cell Subset in Murine Bone Marrow.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Matsushita Y,Chu AKY,Ono W,Welch JD,Ono N
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunocytochemistry
Tue Jun 01 00:00:00 UTC 2021
Macrophage LAMTOR1 Deficiency Prevents Dietary Obesity and Insulin Resistance Through Inflammation-Induced Energy Expenditure.
Frontiers in cell and developmental biology
Ying L,Zhang M,Ma X,Si Y,Li X,Su J,Yin J,Bao Y
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Jun 08 00:00:00 UTC 2021
VX-765 reduces neuroinflammation after spinal cord injury in mice.
Neural regeneration research
Chen J,Chen YQ,Shi YJ,Ding SQ,Shen L,Wang R,Wang QY,Zha C,Ding H,Hu JG,Lü HZ
14-0451-82 was used in Immunohistochemistry to suggest that VX-765 can reduce neuroinflammation and improve nerve function recovery after spinal cord injury by inhibiting caspase-1/interleukin-1β/interleukin-18.
Wed Sep 01 00:00:00 UTC 2021
A novel Cytochrome P450 26A1 expressing NK cell subset at the mouse maternal-foetal interface.
Journal of cellular and molecular medicine
Wei DP,Li DD,Gu AQ,Ji WH,Yang Y,Peng JP
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunocytochemistry
Mon Feb 01 00:00:00 UTC 2021
Maternal Cripto is required for proper uterine decidualization and peri-implantation uterine remodeling.
Biology of reproduction
Shafiei S,Farah O,Dufort D
14-0451-82 was used in Immunohistochemistry-immunofluorescence to investigate Cripto's role in female reproduction.
Fri May 07 00:00:00 UTC 2021
Alterations of macrophage and neutrophil content in skeletal muscle of aged versus young mice.
Muscle & nerve
Kawanishi N,Machida S
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Apr 01 00:00:00 UTC 2021
Differential activation of Ca2+ influx channels modulate stem cell potency, their proliferation/viability and tissue regeneration.
NPJ Regenerative medicine
Ahamad N,Sun Y,Nascimento Da Conceicao V,Xavier Paul Ezhilan CRD,Natarajan M,Singh BB
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Wed Oct 20 00:00:00 UTC 2021
Differential activation of Ca2+ influx channels modulate stem cell potency, their proliferation/viability and tissue regeneration.
NPJ Regenerative medicine
Ahamad N,Sun Y,Nascimento Da Conceicao V,Xavier Paul Ezhilan CRD,Natarajan M,Singh BB
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Wed Oct 20 00:00:00 UTC 2021
Cellular and physiological circadian mechanisms drive diurnal cell proliferation and expansion of white adipose tissue.
Nature communications
Ribas-Latre A,Santos RB,Fekry B,Tamim YM,Shivshankar S,Mohamed AMT,Baumgartner C,Kwok C,Gebhardt C,Rivera A,Gao Z,Sun K,Heiker JT,Snyder BE,Kolonin MG,Eckel-Mahan KL
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunocytochemistry
Wed Jun 09 00:00:00 UTC 2021
Increased Levels of IL-16 in the Central Nervous System during Neuroinflammation Are Associated with Infiltrating Immune Cells and Resident Glial Cells.
Biology
Hridi SU,Barbour M,Wilson C,Franssen AJ,Harte T,Bushell TJ,Jiang HR
14-0451-82 was used in Immunohistochemistry (Frozen) to investigate the correlation between interleukin 16 levels and neuroinflammation severity using an experimental autoimmune encephalomyelitis mouse model.
Thu May 27 00:00:00 UTC 2021
Increased Levels of IL-16 in the Central Nervous System during Neuroinflammation Are Associated with Infiltrating Immune Cells and Resident Glial Cells.
Biology
Hridi SU,Barbour M,Wilson C,Franssen AJ,Harte T,Bushell TJ,Jiang HR
14-0451-82 was used in Immunohistochemistry (Frozen) to investigate the correlation between interleukin 16 levels and neuroinflammation severity using an experimental autoimmune encephalomyelitis mouse model.
Thu May 27 00:00:00 UTC 2021
The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism.
eLife
Roy A,Tomaz da Silva M,Bhat R,Bohnert KR,Iwawaki T,Kumar A
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Nov 23 00:00:00 UTC 2021
VISTA regulates microglia homeostasis and myelin phagocytosis, and is associated with MS lesion pathology.
Acta neuropathologica communications
Borggrewe M,Kooistra SM,Wesseling EM,Gierschek FL,Brummer ML,Nowak EC,Medeiros-Furquim T,Otto TA,Lee SW,Noelle RJ,Eggen BJL,Laman JD
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Tue May 18 00:00:00 UTC 2021
The Absence of Extracellular Cold-Inducible RNA-Binding Protein (eCIRP) Promotes Pro-Angiogenic Microenvironmental Conditions and Angiogenesis in Muscle Tissue Ischemia.
International journal of molecular sciences
Kübler M,Beck S,Peffenköver LL,Götz P,Ishikawa-Ankerhold H,Preissner KT,Fischer S,Lasch M,Deindl E
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunocytochemistry
Tue Aug 31 00:00:00 UTC 2021
Distinct skeletal stem cell types orchestrate long bone skeletogenesis.
eLife
Ambrosi TH,Sinha R,Steininger HM,Hoover MY,Murphy MP,Koepke LS,Wang Y,Lu WJ,Morri M,Neff NF,Weissman IL,Longaker MT,Chan CK
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Jul 19 00:00:00 UTC 2021
C3 Deficiency Leads to Increased Angiogenesis and Elevated Pro-Angiogenic Leukocyte Recruitment in Ischemic Muscle Tissue.
International journal of molecular sciences
Götz P,Braumandl A,Kübler M,Kumaraswami K,Ishikawa-Ankerhold H,Lasch M,Deindl E
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Fri May 28 00:00:00 UTC 2021
Absence of Cold-Inducible RNA-Binding Protein (CIRP) Promotes Angiogenesis and Regeneration of Ischemic Tissue by Inducing M2-Like Macrophage Polarization.
Biomedicines
Kübler M,Beck S,Fischer S,Götz P,Kumaraswami K,Ishikawa-Ankerhold H,Lasch M,Deindl E
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Wed Apr 07 00:00:00 UTC 2021
Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury.
Nature communications
Jin H,Liu K,Tang J,Huang X,Wang H,Zhang Q,Zhu H,Li Y,Pu W,Zhao H,He L,Li Y,Zhang S,Zhang Z,Zhao Y,Qin Y,Pflanz S,Kasmi KEI,Zhang W,Liu Z,Ginhoux F,Ji Y,He B,Wang L,Zhou B
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry (PFA fixed)
Mon May 17 00:00:00 UTC 2021
PTENα functions as an immune suppressor and promotes immune resistance in PTEN-mutant cancer.
Nature communications
Sun Y,Lu D,Yin Y,Song J,Liu Y,Hao W,Qi F,Zhang G,Zhang X,Liu L,Lin Z,Liang H,Zhao X,Jin Y,Yin Y
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Aug 26 00:00:00 UTC 2021
Cardiac-derived TGF-β1 confers resistance to diet-induced obesity through the regulation of adipocyte size and function.
Molecular metabolism
Longenecker JZ,Petrosino JM,Martens CR,Hinger SA,Royer CJ,Dorn LE,Branch DA,Serrano J,Stanford KI,Kyriazis GA,Baskin KK,Accornero F
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Wed Dec 01 00:00:00 UTC 2021
Differential neurovirulence of Usutu virus lineages in mice and neuronal cells.
Journal of neuroinflammation
Clé M,Constant O,Barthelemy J,Desmetz C,Martin MF,Lapeyre L,Cadar D,Savini G,Teodori L,Monaco F,Schmidt-Chanasit J,Saiz JC,Gonzales G,Lecollinet S,Beck C,Gosselet F,Van de Perre P,Foulongne V,Salinas S,Simonin Y
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Wed Jan 06 00:00:00 UTC 2021
Transcriptional Network Analysis Reveals the Role of miR-223-5p During Diabetic Corneal Epithelial Regeneration.
Frontiers in molecular biosciences
Zhang Y,Dou S,Qi X,Zhang Z,Qiao Y,Wang Y,Xie J,Jiang H,Zhang B,Zhou Q,Wang Q,Xie L
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunocytochemistry
Thu Apr 13 00:00:00 UTC 2023
Cytochrome P450 26A1 Modulates the Polarization of Uterine Macrophages During the Peri-Implantation Period.
Frontiers in immunology
Ji WH,Li DD,Wei DP,Gu AQ,Yang Y,Peng JP
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Feb 10 00:00:00 UTC 2022
A molybdenum oxide-based degradable nanosheet for combined chemo-photothermal therapy to improve tumor immunosuppression and suppress distant tumors and lung metastases.
Journal of nanobiotechnology
Qiu N,Yang X,Zhang Y,Zhang J,Ji J,Zhang Y,Kong X,Xi Y,Liu D,Ye L,Zhai G
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Sun Dec 19 00:00:00 UTC 2021
Early Adolescence Prefrontal Cortex Alterations in Female Rats Lacking Dopamine Transporter.
Biomedicines
Illiano P,Leo D,Gainetdinov RR,Pardo M
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Western Blot
Fri Feb 05 00:00:00 UTC 2021
Quantitative in vivo assessment of amyloid-beta phagocytic capacity in an Alzheimer's disease mouse model.
STAR protocols
Lau SF,Wu W,Seo H,Fu AKY,Ip NY
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Mar 19 00:00:00 UTC 2021
Differential chromatin binding of the lung lineage transcription factor NKX2-1 resolves opposing murine alveolar cell fates in vivo.
Nature communications
Little DR,Lynch AM,Yan Y,Akiyama H,Kimura S,Chen J
14-0451-85 was used in Immunohistochemistry (PFA fixed) to report that the cell-type-specific function of NKX2-1 is attributed to its differential chromatin binding that is acquired or retained during development in coordination with partner transcriptional factors.
Tue May 04 00:00:00 UTC 2021
Mice with induced pulmonary morbidities display severe lung inflammation and mortality following exposure to SARS-CoV-2.
JCI insight
Falach R,Bar-On L,Lazar S,Kadar T,Mazor O,Aftalion M,Gur D,Evgy Y,Shifman O,Aminov T,Israeli O,Cohen-Gihon I,Zaide G,Gutman H,Vagima Y,Makdasi E,Stein D,Rosenfeld R,Alcalay R,Zahavy E,Levy H,Glinert I,Ben-Shmuel A,Israely T,Melamed S,Politi B,Achdout H,Yitzhaki S,Kronman C,Sabo T
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Jun 22 00:00:00 UTC 2021
Suppression of mucosal Th17 memory responses by acellular pertussis vaccines enhances nasal Bordetella pertussis carriage.
NPJ vaccines
Dubois V,Chatagnon J,Thiriard A,Bauderlique-Le Roy H,Debrie AS,Coutte L,Locht C
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Jan 08 00:00:00 UTC 2021
Synergistic immunotherapy of glioblastoma by dual targeting of IL-6 and CD40.
Nature communications
Yang F,He Z,Duan H,Zhang D,Li J,Yang H,Dorsey JF,Zou W,Nabavizadeh SA,Bagley SJ,Abdullah K,Brem S,Zhang L,Xu X,Byrne KT,Vonderheide RH,Gong Y,Fan Y
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Jun 08 00:00:00 UTC 2021
The effect of fingolimod on regulatory T cells in a mouse model of brain ischaemia.
Journal of neuroinflammation
Malone K,Diaz Diaz AC,Shearer JA,Moore AC,Waeber C
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Sat Jan 30 00:00:00 UTC 2021
NOX4 regulates macrophage apoptosis resistance to induce fibrotic progression.
The Journal of biological chemistry
Larson-Casey JL,Gu L,Kang J,Dhyani A,Carter AB
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Jul 01 00:00:00 UTC 2021
A decrease in NAD+ contributes to the loss of osteoprogenitors and bone mass with aging.
NPJ aging and mechanisms of disease
Kim HN,Ponte F,Warren A,Ring R,Iyer S,Han L,Almeida M
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Apr 01 00:00:00 UTC 2021
Therapeutic Potential of Mesenchymal Stem Cells in a Pre-Clinical Model of Diabetic Kidney Disease and Obesity.
International journal of molecular sciences
Sávio-Silva C,Soinski-Sousa PE,Simplício-Filho A,Bastos RMC,Beyerstedt S,Rangel ÉB
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Feb 04 00:00:00 UTC 2021
Inflammatory resolution and vascular barrier restoration after retinal ischemia reperfusion injury.
Journal of neuroinflammation
Abcouwer SF,Shanmugam S,Muthusamy A,Lin CM,Kong D,Hager H,Liu X,Antonetti DA
14-0451-82 was used in Immunohistochemistry to suggest that iBRB restoration occurs as TJ complexes are reorganized and that resolution of inflammation and restoration of the iBRB following retinal IR injury are functionally linked.
Thu Aug 26 00:00:00 UTC 2021
Use of a Self-Delivering Anti-CCL3 FANA Oligonucleotide as an Innovative Approach to Target Inflammation after Spinal Cord Injury.
eNeuro
Pelisch N,Rosas Almanza J,Stehlik KE,Aperi BV,Kroner A
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Jun 18 00:00:00 UTC 2021
T cell-depleting nanoparticles ameliorate bone loss by reducing activated T cells and regulating the Treg/Th17 balance.
Bioactive materials
Yang X,Zhou F,Yuan P,Dou G,Liu X,Liu S,Wang X,Jin R,Dong Y,Zhou J,Lv Y,Deng Z,Liu S,Chen X,Han Y,Jin Y
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Oct 01 00:00:00 UTC 2021
Chondrocytes in the resting zone of the growth plate are maintained in a Wnt-inhibitory environment.
eLife
Hallett SA,Matsushita Y,Ono W,Sakagami N,Mizuhashi K,Tokavanich N,Nagata M,Zhou A,Hirai T,Kronenberg HM,Ono N
14-0451-82 was used in Flow Cytometry to conclude that slow-cycling chondrocytes are maintained in a Wnt-inhibitory environment within the resting zone, unraveling a novel mechanism regulating maintenance and differentiation of PTHrP+ skeletal stem cells of the postnatal growth plate.
Mon Jul 26 00:00:00 UTC 2021
Placenta-Expanded Stromal Cell Therapy in a Rodent Model of Simulated Weightlessness.
Cells
Rubinstein L,Paul AM,Houseman C,Abegaz M,Tabares Ruiz S,O'Neil N,Kunis G,Ofir R,Cohen J,Ronca AE,Globus RK,Tahimic CGT
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Apr 19 00:00:00 UTC 2021
Apoptotic vesicles restore liver macrophage homeostasis to counteract type 2 diabetes.
Journal of extracellular vesicles
Zheng C,Sui B,Zhang X,Hu J,Chen J,Liu J,Wu D,Ye Q,Xiang L,Qiu X,Liu S,Deng Z,Zhou J,Liu S,Shi S,Jin Y
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Sat May 01 00:00:00 UTC 2021
Integrated OMICs unveil the bone-marrow microenvironment in human leukemia.
Cell reports
Passaro D,Garcia-Albornoz M,Diana G,Chakravarty P,Ariza-McNaughton L,Batsivari A,Borràs-Eroles C,Abarrategi A,Waclawiczek A,Ombrato L,Malanchi I,Gribben J,Bonnet D
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue May 11 00:00:00 UTC 2021
Epinephrine Production in Th17 Cells and Experimental Autoimmune Encephalitis.
Frontiers in immunology
Yang P,Tian H,Zou YR,Chambon P,Ichinose H,Honig G,Diamond B,Kim SJ
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Jul 05 00:00:00 UTC 2021
Epinephrine Production in Th17 Cells and Experimental Autoimmune Encephalitis.
Frontiers in immunology
Yang P,Tian H,Zou YR,Chambon P,Ichinose H,Honig G,Diamond B,Kim SJ
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Jul 05 00:00:00 UTC 2021
Obesity-Activated Lung Stromal Cells Promote Myeloid Lineage Cell Accumulation and Breast Cancer Metastasis.
Cancers
Hillers-Ziemer LE,Williams AE,Janquart A,Grogan C,Thompson V,Sanchez A,Arendt LM
14-0451-82 was used in Flow Cytometry to suggest that prior to tumor formation, obesity alters the lung microenvironment, creating niches conducive to metastatic growth.
Sun Feb 28 00:00:00 UTC 2021
STING activation normalizes the intraperitoneal vascular-immune microenvironment and suppresses peritoneal carcinomatosis of colon cancer.
Journal for immunotherapy of cancer
Lee SJ,Yang H,Kim WR,Lee YS,Lee WS,Kong SJ,Lee HJ,Kim JH,Cheon J,Kang B,Chon HJ,Kim C
14-0451-82 was used in Flow Cytometry to elucidate the immune-evasion mechanisms during the peritoneal carcinomatosis of colon cancer and developed a novel immunotherapy by activating the stimulator of interferon genes (STING) pathway.
Tue Jun 01 00:00:00 UTC 2021
Determining the effect of aging, recovery time, and post-stroke memantine treatment on delayed thalamic gliosis after cortical infarct.
Scientific reports
Kim GS,Stephenson JM,Al Mamun A,Wu T,Goss MG,Min JW,Li J,Liu F,Marrelli SP
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Jun 15 00:00:00 UTC 2021
Systemic administration of β-glucan induces immune training in microglia.
Journal of neuroinflammation
Heng Y,Zhang X,Borggrewe M,van Weering HRJ,Brummer ML,Nijboer TW,Joosten LAB,Netea MG,Boddeke EWGM,Laman JD,Eggen BJL
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Feb 22 00:00:00 UTC 2021
Visceral adipose tissue imparts peripheral macrophage influx into the hypothalamus.
Journal of neuroinflammation
Chen KE,Lainez NM,Nair MG,Coss D
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Jun 21 00:00:00 UTC 2021
Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation.
Nature
Jiao H,Wachsmuth L,Kumari S,Schwarzer R,Lin J,Eren RO,Fisher A,Lane R,Young GR,Kassiotis G,Kaiser WJ,Pasparakis M
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Wed Apr 01 00:00:00 UTC 2020
Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation.
Nature
Jiao H,Wachsmuth L,Kumari S,Schwarzer R,Lin J,Eren RO,Fisher A,Lane R,Young GR,Kassiotis G,Kaiser WJ,Pasparakis M
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Wed Apr 01 00:00:00 UTC 2020
Macrophages Maintain Epithelium Integrity by Limiting Fungal Product Absorption.
Cell
Chikina AS,Nadalin F,Maurin M,San-Roman M,Thomas-Bonafos T,Li XV,Lameiras S,Baulande S,Henri S,Malissen B,Lacerda Mariano L,Barbazan J,Blander JM,Iliev ID,Matic Vignjevic D,Lennon-Duménil AM
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Oct 15 00:00:00 UTC 2020
Regenerative Metaplastic Clones in COPD Lung Drive Inflammation and Fibrosis.
Cell
Rao W,Wang S,Duleba M,Niroula S,Goller K,Xie J,Mahalingam R,Neupane R,Liew AA,Vincent M,Okuda K,O'Neal WK,Boucher RC,Dickey BF,Wechsler ME,Ibrahim O,Engelhardt JF,Mertens TCJ,Wang W,Jyothula SSK,Crum CP,Karmouty-Quintana H,Parekh KR,Metersky ML,McKeon FD,Xian W
14-0451-85 was used in Immunohistochemistry (Paraffin) to inundate COPD lungs by three variant progenitors epigenetically committed to distinct metaplastic lesions.
Thu May 14 00:00:00 UTC 2020
Transdifferentiation of tumor infiltrating innate lymphoid cells during progression of colorectal cancer.
Cell research
Wang S,Qu Y,Xia P,Chen Y,Zhu X,Zhang J,Wang G,Tian Y,Ying J,Fan Z
14-0451-82 was used in Flow Cytometry to profile tumor infiltrating innate lymphoid cells in colorectal cancer at early and late stages.
Wed Jul 01 00:00:00 UTC 2020
The Cytokine TGF-β Induces Interleukin-31 Expression from Dermal Dendritic Cells to Activate Sensory Neurons and Stimulate Wound Itching.
Immunity
Xu J,Zanvit P,Hu L,Tseng PY,Liu N,Wang F,Liu O,Zhang D,Jin W,Guo N,Han Y,Yin J,Cain A,Hoon MA,Wang S,Chen W
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Aug 18 00:00:00 UTC 2020
Microglial microRNAs mediate sex-specific responses to tau pathology.
Nature neuroscience
Kodama L,Guzman E,Etchegaray JI,Li Y,Sayed FA,Zhou L,Zhou Y,Zhan L,Le D,Udeochu JC,Clelland CD,Cheng Z,Yu G,Li Q,Kosik KS,Gan L
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Sat Feb 01 00:00:00 UTC 2020
Decreased lymphatic HIF-2α accentuates lymphatic remodeling in lymphedema.
The Journal of clinical investigation
Jiang X,Tian W,Granucci EJ,Tu AB,Kim D,Dahms P,Pasupneti S,Peng G,Kim Y,Lim AH,Espinoza FH,Cribb M,Dixon JB,Rockson SG,Semenza GL,Nicolls MR
14-0451 was used in Immunohistochemistry to investigate the role of the Hif2a in lymphatic endothelial cells and its contribution to disease parthenogenesis when it is dysregulated.
Thu Oct 01 00:00:00 UTC 2020
Exposure to diesel exhaust particles increases susceptibility to invasive pneumococcal disease.
The Journal of allergy and clinical immunology
Shears RK,Jacques LC,Naylor G,Miyashita L,Khandaker S,Lebre F,Lavelle EC,Grigg J,French N,Neill DR,Kadioglu A
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Wed Apr 01 00:00:00 UTC 2020
Modulation of the functions of myeloid-derived suppressor cells : a new strategy of hydrogen sulfide anti-cancer effects.
British journal of pharmacology
De Cicco P,Ercolano G,Rubino V,Terrazzano G,Ruggiero G,Cirino G,Ianaro A
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Sat Feb 01 00:00:00 UTC 2020
Membrane expression of the estrogen receptor ERα is required for intercellular communications in the mammary epithelium.
Development (Cambridge, England)
Gagniac L,Rusidzé M,Boudou F,Cagnet S,Adlanmerini M,Jeannot P,Gaide N,Giton F,Besson A,Weyl A,Gourdy P,Raymond-Letron I,Arnal JF,Brisken C,Lenfant F
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Wed Mar 11 00:00:00 UTC 2020
Dysfunction of B Cell Leading to Failure of Immunoglobulin Response Is Ameliorated by Dietary Silk Peptide in 14-Month-Old C57BL/6 Mice.
Frontiers in nutrition
Chei S,Oh HJ,Lee K,Jin H,Lee JY,Lee BY
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Dec 18 00:00:00 UTC 2020
Sema3A and HIF1α co-overexpressed iPSC-MSCs/HA scaffold facilitates the repair of calvarial defect in a mouse model.
Journal of cellular physiology
Li J,Wang T,Li C,Wang Z,Wang P,Zheng L
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Oct 01 00:00:00 UTC 2020
Detection of Synaptic Proteins in Microglia by Flow Cytometry.
Frontiers in molecular neuroscience
Brioschi S,d'Errico P,Amann LS,Janova H,Wojcik SM,Meyer-Luehmann M,Rajendran L,Wieghofer P,Paolicelli RC,Biber K
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Nov 03 00:00:00 UTC 2020
Upregulation of Extracellular Vesicles-Encapsulated miR-132 Released From Mesenchymal Stem Cells Attenuates Ischemic Neuronal Injury by Inhibiting Smad2/c-jun Pathway via Acvr2b Suppression.
Frontiers in cell and developmental biology
Feng B,Meng L,Luan L,Fang Z,Zhao P,Zhao G
14-0451 was used in Flow cytometry/Cell sorting to demonstrate that activin receptor type IIB expression is inhibited by miR-132 from mesenchymal stem cells which attenuates ischemic neuronal injury.
Fri Mar 26 00:00:00 UTC 2021
Extracellular adenosine enhances the ability of PMNs to kill Streptococcus pneumoniae by inhibiting IL-10 production.
Journal of leukocyte biology
Siwapornchai N,Lee JN,Tchalla EYI,Bhalla M,Yeoh JH,Roggensack SE,Leong JM,Bou Ghanem EN
14-0451-82 was used in Flow Cytometry to explore why the antimicrobial efficacy of polymorphonuclear leukocytes declines over the course of infection.
Tue Sep 01 00:00:00 UTC 2020
Quantitative single-cell interactomes in normal and virus-infected mouse lungs.
Disease models & mechanisms
Cain MP,Hernandez BJ,Chen J
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunocytochemistry
Fri Jun 26 00:00:00 UTC 2020
Quantitative single-cell interactomes in normal and virus-infected mouse lungs.
Disease models & mechanisms
Cain MP,Hernandez BJ,Chen J
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunocytochemistry
Fri Jun 26 00:00:00 UTC 2020
Secreted Phospholipase A2 Group X Acts as an Adjuvant for Type 2 Inflammation, Leading to an Allergen-Specific Immune Response in the Lung.
Journal of immunology (Baltimore, Md. : 1950)
Ogden HL,Lai Y,Nolin JD,An D,Frevert CW,Gelb MH,Altemeier WA,Hallstrand TS
14-0451-82 was used in Flow Cytometry to demonstrate that exogenous and endogenous sPLA2s play an important role in peripheral sensitization, resulting in airway responses to inhaled Ags.
Mon Jun 15 00:00:00 UTC 2020
Extracellular HMGB-1 activates inflammatory signaling in tendon cells and tissues.
Therapeutic advances in chronic disease
Zhang C,Gu X,Zhao G,Wang W,Shao J,Zhu J,Yuan T,Sun J,Nie D,Zhou Y
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Sun Apr 17 00:00:00 UTC 2022
Virtual measurements of paracellular permeability and chronic inflammation via color coded pixel-wise T1 mapping.
American journal of physiology. Renal physiology
Singh N,Zabbarova I,Ikeda Y,Maranchie J,Chermansky C,Foley L,Hitchens TK,Yoshimura N,Kanai A,Kaufman J,Tyagi P
14-0451-82 was used in Immunohistochemistry to assess whether quantitative T1 relaxometry can measure permeability, chronic inflammation and mural thickening of mouse bladder wall.
Tue Sep 01 00:00:00 UTC 2020
Tissue Inhibitor of Metalloproteinases-2 Mediates Kidney Injury during Sepsis.
Nephron
Wen X,Zhang J,Wan X,Frank AA,Qu X,Kellum JA
14-0451 was used in Immunohistochemistry-immunofluorescence to propose that urinary tissue inhibitor of metalloproteinases-2 mediates sepsis-associated acute kidney injury and appears to be a viable drug target.
Tue Oct 26 00:00:00 UTC 2021
Resveratrol rescues TNF‑α‑induced inhibition of osteogenesis in human periodontal ligament stem cells via the ERK1/2 pathway.
Molecular medicine reports
Yuan J,Wang X,Ma D,Gao H,Zheng D,Zhang J
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri May 01 00:00:00 UTC 2020
Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity.
Nature communications
von Roemeling CA,Wang Y,Qie Y,Yuan H,Zhao H,Liu X,Yang Z,Yang M,Deng W,Bruno KA,Chan CK,Lee AS,Rosenfeld SS,Yun K,Johnson AJ,Mitchell DA,Jiang W,Kim BYS
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Fri Mar 20 00:00:00 UTC 2020
Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity.
Nature communications
von Roemeling CA,Wang Y,Qie Y,Yuan H,Zhao H,Liu X,Yang Z,Yang M,Deng W,Bruno KA,Chan CK,Lee AS,Rosenfeld SS,Yun K,Johnson AJ,Mitchell DA,Jiang W,Kim BYS
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Fri Mar 20 00:00:00 UTC 2020
Study of Usutu virus neuropathogenicity in mice and human cellular models.
PLoS neglected tropical diseases
Clé M,Barthelemy J,Desmetz C,Foulongne V,Lapeyre L,Bolloré K,Tuaillon E,Erkilic N,Kalatzis V,Lecollinet S,Beck C,Pirot N,Glasson Y,Gosselet F,Alvarez Martinez MT,Van de Perre P,Salinas S,Simonin Y
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Wed Apr 01 00:00:00 UTC 2020
Zika Virus Infection Promotes Local Inflammation, Cell Adhesion Molecule Upregulation, and Leukocyte Recruitment at the Blood-Brain Barrier.
mBio
Clé M,Desmetz C,Barthelemy J,Martin MF,Constant O,Maarifi G,Foulongne V,Bolloré K,Glasson Y,De Bock F,Blaquiere M,Dehouck L,Pirot N,Tuaillon E,Nisole S,Najioullah F,Van de Perre P,Cabié A,Marchi N,Gosselet F,Simonin Y,Salinas S
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Tue Aug 04 00:00:00 UTC 2020
Zika Virus Infection Promotes Local Inflammation, Cell Adhesion Molecule Upregulation, and Leukocyte Recruitment at the Blood-Brain Barrier.
mBio
Clé M,Desmetz C,Barthelemy J,Martin MF,Constant O,Maarifi G,Foulongne V,Bolloré K,Glasson Y,De Bock F,Blaquiere M,Dehouck L,Pirot N,Tuaillon E,Nisole S,Najioullah F,Van de Perre P,Cabié A,Marchi N,Gosselet F,Simonin Y,Salinas S
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Tue Aug 04 00:00:00 UTC 2020
Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers.
Nature communications
Okazaki K,Anzawa H,Liu Z,Ota N,Kitamura H,Onodera Y,Alam MM,Matsumaru D,Suzuki T,Katsuoka F,Tadaka S,Motoike I,Watanabe M,Hayasaka K,Sakurada A,Okada Y,Yamamoto M,Suzuki T,Kinoshita K,Sekine H,Motohashi H
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Nov 20 00:00:00 UTC 2020
Eosinophils improve cardiac function after myocardial infarction.
Nature communications
Liu J,Yang C,Liu T,Deng Z,Fang W,Zhang X,Li J,Huang Q,Liu C,Wang Y,Yang D,Sukhova GK,Lindholt JS,Diederichsen A,Rasmussen LM,Li D,Newton G,Luscinskas FW,Liu L,Libby P,Wang J,Guo J,Shi GP
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Wed Dec 16 00:00:00 UTC 2020
TEX15 is an essential executor of MIWI2-directed transposon DNA methylation and silencing.
Nature communications
Schöpp T,Zoch A,Berrens RV,Auchynnikava T,Kabayama Y,Vasiliauskaitė L,Rappsilber J,Allshire RC,O'Carroll D
14-0451-82 was used in Flow Cytometry to show that TEX15 is an essential executor of mammalian PIWI-interacting RNA-directed DNA methylation.
Mon Jul 27 00:00:00 UTC 2020
CRID3, a blocker of apoptosis associated speck like protein containing a card, ameliorates murine spinal cord injury by improving local immune microenvironment.
Journal of neuroinflammation
Chen YQ,Wang SN,Shi YJ,Chen J,Ding SQ,Tang J,Shen L,Wang R,Ding H,Hu JG,Lü HZ
14-0451-85 was used in Immunohistochemistry (Frozen) to study the effect of CRID3 on the local microenvironment and the possible role in neuroprotection following spinal cord injury.
Sat Aug 29 00:00:00 UTC 2020
Ly6cLo non-classical monocytes promote resolution of rhesus rotavirus-mediated perinatal hepatic inflammation.
Scientific reports
Alkhani A,Levy CS,Tsui M,Rosenberg KA,Polovina K,Mattis AN,Mack M,Van Dyken S,Wang BM,Maher JJ,Nijagal A
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Apr 28 00:00:00 UTC 2020
Stromal CCL2 Signaling Promotes Mammary Tumor Fibrosis through Recruitment of Myeloid-Lineage Cells.
Cancers
Kuziel G,Thompson V,D'Amato JV,Arendt LM
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Jul 28 00:00:00 UTC 2020
Targeting the Wnt signaling pathway through R-spondin 3 identifies an anti-fibrosis treatment strategy for multiple organs.
PloS one
Zhang M,Haughey M,Wang NY,Blease K,Kapoun AM,Couto S,Belka I,Hoey T,Groza M,Hartke J,Bennett B,Cain J,Gurney A,Benish B,Castiglioni P,Drew C,Lachowicz J,Carayannopoulos L,Nathan SD,Distler J,Brenner DA,Hariharan K,Cho H,Xie W
14-0451-82 was used in Immunohistochemistry to provide an anti-fibrotic strategy for targeting the Wnt/β-catenin pathway through RSPO3 blockade and support that OMP-131R10 could be an important therapeutic agent for fibrosis.
Tue Jul 07 00:00:00 UTC 2020
Small GTPase RAB6 deficiency promotes alveolar progenitor cell renewal and attenuates PM2.5-induced lung injury and fibrosis.
Cell death & disease
Yang L,Liu G,Li X,Xia Z,Wang Y,Lin W,Zhang W,Zhang W,Li X
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Sun Oct 04 00:00:00 UTC 2020
Interferon Alpha Favors Macrophage Infection by Visceral Leishmania Species Through Upregulation of Sialoadhesin Expression.
Frontiers in immunology
Van Bockstal L,Bulté D,Van den Kerkhof M,Dirkx L,Mabille D,Hendrickx S,Delputte P,Maes L,Caljon G
14-0451-82 was used in Flow Cytometry to assess the impact of type I IFN on macrophage infection with L. infantum and L. donovani and the implication of sialoadhesin as an IFN-inducible surface receptor.
Fri Apr 02 00:00:00 UTC 2021
A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation.
Nature communications
Kim JM,Yang YS,Park KH,Ge X,Xu R,Li N,Song M,Chun H,Bok S,Charles JF,Filhol-Cochet O,Boldyreff B,Dinter T,Yu PB,Kon N,Gu W,Takarada T,Greenblatt MB,Shim JH
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri May 08 00:00:00 UTC 2020
Analysis of the immune response to sciatic nerve injury identifies efferocytosis as a key mechanism of nerve debridement.
eLife
Kalinski AL,Yoon C,Huffman LD,Duncker PC,Kohen R,Passino R,Hafner H,Johnson C,Kawaguchi R,Carbajal KS,Jara JS,Hollis E,Geschwind DH,Segal BM,Giger RJ
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Wed Dec 02 00:00:00 UTC 2020
Resolvin D1 supports skeletal myofiber regeneration via actions on myeloid and muscle stem cells.
JCI insight
Markworth JF,Brown LA,Lim E,Floyd C,Larouche J,Castor-Macias JA,Sugg KB,Sarver DC,Macpherson PC,Davis C,Aguilar CA,Maddipati KR,Brooks SV
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Sep 17 00:00:00 UTC 2020
Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations.
Journal of neuroinflammation
Lowe PP,Morel C,Ambade A,Iracheta-Vellve A,Kwiatkowski E,Satishchandran A,Furi I,Cho Y,Gyongyosi B,Catalano D,Lefebvre E,Fischer L,Seyedkazemi S,Schafer DP,Szabo G
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Oct 09 00:00:00 UTC 2020
Increased FGF-23 levels are linked to ineffective erythropoiesis and impaired bone mineralization in myelodysplastic syndromes.
JCI insight
Weidner H,Baschant U,Lademann F,Ledesma Colunga MG,Balaian E,Hofbauer C,Misof BM,Roschger P,Blouin S,Richards WG,Platzbecker U,Hofbauer LC,Rauner M
14-0451-82 was used in Flow Cytometry to identify FGF-23 as a link between altered bone structure and ineffective erythropoiesis in MDS with the prospects of a targeted therapeutic intervention.
Thu Aug 06 00:00:00 UTC 2020
Regorafenib combined with PD1 blockade increases CD8 T-cell infiltration by inducing CXCL10 expression in hepatocellular carcinoma.
Journal for immunotherapy of cancer
Shigeta K,Matsui A,Kikuchi H,Klein S,Mamessier E,Chen IX,Aoki S,Kitahara S,Inoue K,Shigeta A,Hato T,Ramjiawan RR,Staiculescu D,Zopf D,Fiebig L,Hobbs GS,Quaas A,Dima S,Popescu I,Huang P,Munn LL,Cobbold M,Goyal L,Zhu AX,Jain RK,Duda DG
14-0451-82 was used in Flow Cytometry to conclude that judicious regorafenib/anti-PD1 combination therapy can inhibit tumor growth and increase survival by normalizing tumor vasculature and increasing intratumoral CXCR3+CD8 T-cell infiltration through elevated CXCL10 expression in HCC cells.
Sun Nov 01 00:00:00 UTC 2020
Delayed microglial depletion after spinal cord injury reduces chronic inflammation and neurodegeneration in the brain and improves neurological recovery in male mice.
Theranostics
Li Y,Ritzel RM,Khan N,Cao T,He J,Lei Z,Matyas JJ,Sabirzhanov B,Liu S,Li H,Stoica BA,Loane DJ,Faden AI,Wu J
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Jun 01 00:00:00 UTC 2021
Inhibition of formyl peptide receptors improves the outcome in a mouse model of Alzheimer disease.
Journal of neuroinflammation
Schröder N,Schaffrath A,Welter JA,Putzka T,Griep A,Ziegler P,Brandt E,Samer S,Heneka MT,Kaddatz H,Zhan J,Kipp E,Pufe T,Tauber SC,Kipp M,Brandenburg LO
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Apr 24 00:00:00 UTC 2020
Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target.
JCI insight
Pierini S,Tanyi JL,Simpkins F,George E,Uribe-Herranz M,Drapkin R,Burger R,Morgan MA,Facciabene A
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Aug 20 00:00:00 UTC 2020
Butyrophilin-like proteins display combinatorial diversity in selecting and maintaining signature intraepithelial γδ T cell compartments.
Nature communications
Jandke A,Melandri D,Monin L,Ushakov DS,Laing AG,Vantourout P,East P,Nitta T,Narita T,Takayanagi H,Feederle R,Hayday A
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Jul 28 00:00:00 UTC 2020
Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models.
Communications biology
Waaler J,Mygland L,Tveita A,Strand MF,Solberg NT,Olsen PA,Aizenshtadt A,Fauskanger M,Lund K,Brinch SA,Lycke M,Dybing E,Nygaard V,Bøe SL,Heintz KM,Hovig E,Hammarström C,Corthay A,Krauss S
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Apr 24 00:00:00 UTC 2020
Targeted lymphodepletion with a CD45-directed antibody radioconjugate as a novel conditioning regimen prior to adoptive cell therapy.
Oncotarget
Dawicki W,Allen KJH,Garg R,Geoghegan EM,Berger MS,Ludwig DL,Dadachova E
14-0451-85 was used in Flow Cytometry to investigate the effect of anti-CD45 radioimmunotherapy lymphodepletion on immune cell types and on tumor control in a model of adoptive cell therapy.
Tue Sep 29 00:00:00 UTC 2020
PPARγ inhibition boosts efficacy of PD-L1 Checkpoint Blockade Immunotherapy against Murine Melanoma in a sexually dimorphic manner.
International journal of biological sciences
Wu B,Sun X,Yuan B,Ge F,Gupta HB,Chiang HC,Li J,Hu Y,Curiel TJ,Li R
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Aug 23 00:00:00 UTC 2021
A Synthetic Small Molecule F240B Decreases NLRP3 Inflammasome Activation by Autophagy Induction.
Frontiers in immunology
Wu CH,Gan CH,Li LH,Chang JC,Chen ST,Menon MP,Cheng SM,Yang SP,Ho CL,Chernikov OV,Lin CH,Lam Y,Hua KF
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Wed Jun 23 00:00:00 UTC 2021
CNS Immune Profiling in a Dengue Virus-Infected Immunocompetent Outbred ICR Mice Strain.
Frontiers in cellular and infection microbiology
Shen TJ,Chen CL,Jhan MK,Tseng PC,Lin CF
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Jun 17 00:00:00 UTC 2021
Osterix-Cre marks distinct subsets of CD45- and CD45+ stromal populations in extra-skeletal tumors with pro-tumorigenic characteristics.
eLife
Ricci B,Tycksen E,Celik H,Belle JI,Fontana F,Civitelli R,Faccio R
14-0451-85 was used in Immunohistochemistry (Paraffin), Immunohistochemistry to find Osx transcript and Osx protein expression early during hematopoiesis, in subsets of hematopoietic stem cells and multipotent progenitor populations.
Wed Aug 05 00:00:00 UTC 2020
Osterix-Cre marks distinct subsets of CD45- and CD45+ stromal populations in extra-skeletal tumors with pro-tumorigenic characteristics.
eLife
Ricci B,Tycksen E,Celik H,Belle JI,Fontana F,Civitelli R,Faccio R
14-0451-85 was used in Immunohistochemistry (Paraffin), Immunohistochemistry to find Osx transcript and Osx protein expression early during hematopoiesis, in subsets of hematopoietic stem cells and multipotent progenitor populations.
Wed Aug 05 00:00:00 UTC 2020
Apoptotic bodies derived from mesenchymal stem cells promote cutaneous wound healing via regulating the functions of macrophages.
Stem cell research & therapy
Liu J,Qiu X,Lv Y,Zheng C,Dong Y,Dou G,Zhu B,Liu A,Wang W,Zhou J,Liu S,Liu S,Gao B,Jin Y
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Nov 27 00:00:00 UTC 2020
Phosphatase SHP1 impedes mesenchymal stromal cell immunosuppressive capacity modulated by JAK1/STAT3 and P38 signals.
Cell & bioscience
Jiang M,Ye J,Wang X,Li N,Wang Y,Shi Y
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Apr 14 00:00:00 UTC 2022
Mesenchymal Stromal Cell-Derived Exosomes Contribute to Epithelial Regeneration in Experimental Inflammatory Bowel Disease.
Cellular and molecular gastroenterology and hepatology
Barnhoorn MC,Plug L,Jonge ESMM,Molenkamp D,Bos E,Schoonderwoerd MJA,Corver WE,van der Meulen-de Jong AE,Verspaget HW,Hawinkels LJAC
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon May 10 00:00:00 UTC 2021
Chronic Inflammation Directs an Olfactory Stem Cell Functional Switch from Neuroregeneration to Immune Defense.
Cell stem cell
Chen M,Reed RR,Lane AP
14-0451 was used in Immunohistochemistry to establish a mechanism whereby chronic rhinosinusitis inflammation causes a functional switch of neuroepithelial stem cells from regeneration to immune defense.
Thu Oct 03 00:00:00 UTC 2019
Bone marrow dendritic cells regulate hematopoietic stem/progenitor cell trafficking.
The Journal of clinical investigation
Zhang J,Supakorndej T,Krambs JR,Rao M,Abou-Ezzi G,Ye RY,Li S,Trinkaus K,Link DC
14-0451 was used in Flow cytometry/Cell sorting to show that HSPC mobilization after cDC ablation is attenuated in mice lacking CXCR2 expression.
Tue Apr 30 00:00:00 UTC 2019
RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury.
Cell death and differentiation
Krishna-Subramanian S,Singer S,Armaka M,Banales JM,Holzer K,Schirmacher P,Walczak H,Kollias G,Pasparakis M,Kondylis V
14-0451 was used in Immunohistochemistry to study the role of cell death on liver disease progression.
Sun Dec 01 00:00:00 UTC 2019
Gut microbiota regulates lacteal integrity by inducing VEGF-C in intestinal villus macrophages.
EMBO reports
Suh SH,Choe K,Hong SP,Jeong SH,Mäkinen T,Kim KS,Alitalo K,Surh CD,Koh GY,Song JH
14-0451-82 was used in Flow Cytometry to explore whether and how the gut microbiota regulates the integrity of the lacteal, a blunt-ended, long, tube-like lymphatic vessel located in the center of each intestinal villus that provides a unique route for drainage of absorbed lipids from the small intestine.
Mon Apr 01 00:00:00 UTC 2019
The ROP16III-dependent early immune response determines the subacute CNS immune response and type III Toxoplasma gondii survival.
PLoS pathogens
Tuladhar S,Kochanowsky JA,Bhaskara A,Ghotmi Y,Chandrasekaran S,Koshy AA
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Oct 01 00:00:00 UTC 2019
Distinct Tie2 tyrosine phosphorylation sites dictate phenotypic switching in endothelial progenitor cells.
Journal of cellular physiology
Siavashi V,Nassiri SM,Rahbarghazi R,Mohseni Z,Sharifi AM
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Wed May 01 00:00:00 UTC 2019
Protumoral bone marrow-derived cells migrate via Gβγ-dependent signaling pathways and exhibit a complex repertoire of RhoGEFs.
Journal of cell communication and signaling
Cervantes-Villagrana RD,Color-Aparicio VM,Reyes-Cruz G,Vázquez-Prado J
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Sat Jun 01 00:00:00 UTC 2019
Critical Adverse Impact of IL-6 in Acute Pneumovirus Infection.
Journal of immunology (Baltimore, Md. : 1950)
Percopo CM,Ma M,Brenner TA,Krumholz JO,Break TJ,Laky K,Rosenberg HF
14-0451 was used in Flow cytometry/Cell sorting to examine the role of the pleiotropic cytokine IL-6 in acute infection with pneumonia virus of mice.
Fri Feb 01 00:00:00 UTC 2019
Antiallodynic Effects of Cannabinoid Receptor 2 (CB2R) Agonists on Retrovirus Infection-Induced Neuropathic Pain.
Pain research & management
Sheng WS,Chauhan P,Hu S,Prasad S,Lokensgard JR
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Dec 16 00:00:00 UTC 2019
Antitumor and immunomodulatory effects of a novel multitarget inhibitor, CS2164, in mouse hepatocellular carcinoma models.
Anti-cancer drugs
Zhou Y,Fu C,Kong Y,Pan D,Wang Y,Huang S,Li Z,Ning Z,Lu X,Shan S,Xin L
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Oct 01 00:00:00 UTC 2019
Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis.
eLife
Walsh CM,Hill RZ,Schwendinger-Schreck J,Deguine J,Brock EC,Kucirek N,Rifi Z,Wei J,Gronert K,Brem RB,Barton GM,Bautista DM
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Mon Oct 21 00:00:00 UTC 2019
Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis.
eLife
Walsh CM,Hill RZ,Schwendinger-Schreck J,Deguine J,Brock EC,Kucirek N,Rifi Z,Wei J,Gronert K,Brem RB,Barton GM,Bautista DM
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Mon Oct 21 00:00:00 UTC 2019
CSF1R antagonism limits local restimulation of antiviral CD8+ T cells during viral encephalitis.
Journal of neuroinflammation
Funk KE,Klein RS
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Jan 31 00:00:00 UTC 2019
Autophagy regulates inflammatory programmed cell death via turnover of RHIM-domain proteins.
eLife
Lim J,Park H,Heisler J,Maculins T,Roose-Girma M,Xu M,Mckenzie B,van Lookeren Campagne M,Newton K,Murthy A
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Jul 09 00:00:00 UTC 2019
The microRNAs miR-204 and miR-211 maintain joint homeostasis and protect against osteoarthritis progression.
Nature communications
Huang J,Zhao L,Fan Y,Liao L,Ma PX,Xiao G,Chen D
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Jun 28 00:00:00 UTC 2019
Discrete viral E2 lysine residues and scavenger receptor MARCO are required for clearance of circulating alphaviruses.
eLife
Carpentier KS,Davenport BJ,Haist KC,McCarthy MK,May NA,Robison A,Ruckert C,Ebel GD,Morrison TE
14-0451-82 was used in Flow Cytometry to reveal a previously unrecognized innate immune pathway that controls alphavirus viremia and dissemination in vertebrate hosts, ultimately influencing disease severity and likely transmission efficiency.
Wed Oct 09 00:00:00 UTC 2019
MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment.
Journal for immunotherapy of cancer
Fang DD,Tang Q,Kong Y,Wang Q,Gu J,Fang X,Zou P,Rong T,Wang J,Yang D,Zhai Y
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Nov 28 00:00:00 UTC 2019
Muscularis Propria Macrophages Alter the Proportion of Nitrergic but Not Cholinergic Gastric Myenteric Neurons.
Cellular and molecular gastroenterology and hepatology
Cipriani G,Terhaar ML,Eisenman ST,Ji S,Linden DR,Wright AM,Sha L,Ordog T,Szurszewski JH,Gibbons SJ,Farrugia G
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Jun 04 00:00:00 UTC 2019
Exposure to Cigarette Smoke Augments Post-ischemic Brain Injury and Inflammation via Mobilization of Neutrophils and Monocytes.
Frontiers in immunology
Li H,Li X,Gao S,Wang D,Gao X,Li Y,Wang X,Cui Z,Ma H,Liu Q,Li M
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Sep 28 00:00:00 UTC 2020
Prim-O-glucosylcimifugin enhances the antitumour effect of PD-1 inhibition by targeting myeloid-derived suppressor cells.
Journal for immunotherapy of cancer
Gao W,Zhang X,Yang W,Dou D,Zhang H,Tang Y,Zhong W,Meng J,Bai Y,Liu Y,Yang L,Chen S,Liu H,Yang C,Sun T
14-0451-82 was used in Flow Cytometry to investigate if a potential option for enhancing the efficacy of PD-1 inhibitors in clinical applications exists.
Wed Aug 28 00:00:00 UTC 2019
Pyruvate kinase M2 is requisite for Th1 and Th17 differentiation.
JCI insight
Kono M,Maeda K,Stocton-Gavanescu I,Pan W,Umeda M,Katsuyama E,Burbano C,Orite SYK,Vukelic M,Tsokos MG,Yoshida N,Tsokos GC
14-0451 was used in Flow cytometry/Cell sorting to demonstrate that CaMK4 binds to PKM2 and promotes its activity, which is requisite for Th1 and Th17 differentiation.
Thu Jun 20 00:00:00 UTC 2019
FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy.
eLife
Diaz Osterman CJ,Ozmadenci D,Kleinschmidt EG,Taylor KN,Barrie AM,Jiang S,Bean LM,Sulzmaier FJ,Jean C,Tancioni I,Anderson K,Uryu S,Cordasco EA,Li J,Chen XL,Fu G,Ojalill M,Rappu P,Heino J,Mark AM,Xu G,Fisch KM,Kolev VN,Weaver DT,Pachter JA,Győrffy B,McHale MT,Connolly DC,Molinolo A,Stupack DG,Schlaepfer DD
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Sep 03 00:00:00 UTC 2019
Extracellular matrix turnover and inflammation in chemically-induced TMJ arthritis mouse models.
PloS one
Morel M,Ruscitto A,Pylawka S,Reeve G,Embree MC
14-0451 was used in Immunohistochemistry to provide two methods of chemically induced TMJ inflammatory arthritis through a condyle explant model and intra-articular injection model that replicate findings seen in synovial fluid of human patients, which can be used for further studies delineating the mechanisms underlying TMJ pathology.
Tue Mar 10 00:00:00 UTC 2020
IL-21 Controls ILC3 Cytokine Production and Promotes a Protective Phenotype in a Mouse Model of Colitis.
ImmunoHorizons
Poholek CH,Dulson SJ,Zajac AJ,Harrington LE
14-0451 was used in Flow cytometry/Cell sorting to reveal a novel role for IL-21 in shaping innate lymphoid cell responses in the intestine and provide one mechanism by which effector CD4 T cells can influence innate immunity.
Tue Jun 04 00:00:00 UTC 2019
PDGFRα+ stromal adipocyte progenitors transition into epithelial cells during lobulo-alveologenesis in the murine mammary gland.
Nature communications
Joshi PA,Waterhouse PD,Kasaian K,Fang H,Gulyaeva O,Sul HS,Boutros PC,Khokha R
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Apr 15 00:00:00 UTC 2019
Growth Factor Screening in Dystrophic Muscles Reveals PDGFB/PDGFRB-Mediated Migration of Interstitial Stem Cells.
International journal of molecular sciences
Camps J,Grosemans H,Gijsbers R,Maes C,Sampaolesi M
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Mar 05 00:00:00 UTC 2019
Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.
Cell
Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Jun 28 00:00:00 UTC 2018
Chanzyme TRPM7 Mediates the Ca2+ Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation.
Immunity
Schappe MS,Szteyn K,Stremska ME,Mendu SK,Downs TK,Seegren PV,Mahoney MA,Dixit S,Krupa JK,Stipes EJ,Rogers JS,Adamson SE,Leitinger N,Desai BN
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Jan 16 00:00:00 UTC 2018
E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor.
Immunity
Li Q,Li D,Zhang X,Wan Q,Zhang W,Zheng M,Zou L,Elly C,Lee JH,Liu YC
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Feb 20 00:00:00 UTC 2018
Rapid chromatin repression by Aire provides precise control of immune tolerance.
Nature immunology
Koh AS,Miller EL,Buenrostro JD,Moskowitz DM,Wang J,Greenleaf WJ,Chang HY,Crabtree GR
14-0451 was used in Flow cytometry/Cell sorting to demonstrate that Brg1 and Aire fine-tune the expression of tissue-specific genes at levels that prevent toxicity yet promote immune tolerance.
Thu Feb 01 00:00:00 UTC 2018
Muscle Satellite Cell Cross-Talk with a Vascular Niche Maintains Quiescence via VEGF and Notch Signaling.
Cell stem cell
Verma M,Asakura Y,Murakonda BSR,Pengo T,Latroche C,Chazaud B,McLoon LK,Asakura A
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Oct 04 00:00:00 UTC 2018
Endothelial cells in the innate response to allergens and initiation of atopic asthma.
The Journal of clinical investigation
Asosingh K,Weiss K,Queisser K,Wanner N,Yin M,Aronica M,Erzurum S
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Mon Jul 02 00:00:00 UTC 2018
Fas ligand promotes an inducible TLR-dependent model of cutaneous lupus-like inflammation.
The Journal of clinical investigation
Mande P,Zirak B,Ko WC,Taravati K,Bride KL,Brodeur TY,Deng A,Dresser K,Jiang Z,Ettinger R,Fitzgerald KA,Rosenblum MD,Harris JE,Marshak-Rothstein A
14-0451 was used in Flow cytometry/Cell sorting to provide a relevant system for exploring the pathophysiology of cutaneous lupus erythematosus (CLE) as well as the negative regulatory role of TLR9.
Mon Jul 02 00:00:00 UTC 2018
Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart.
The Journal of clinical investigation
Fu X,Khalil H,Kanisicak O,Boyer JG,Vagnozzi RJ,Maliken BD,Sargent MA,Prasad V,Valiente-Alandi I,Blaxall BC,Molkentin JD
14-0451 was used in Immunohistochemistry to analyse and classify resident cardiac fibroblast dynamics during myocardial infarction injury and stable scar formation.
Tue May 01 00:00:00 UTC 2018
Lysyl oxidase like-2 contributes to renal fibrosis in Col4α3/Alport mice.
Kidney international
Cosgrove D,Dufek B,Meehan DT,Delimont D,Hartnett M,Samuelson G,Gratton MA,Phillips G,MacKenna DA,Bain G
14-0451 was used in Immunohistochemistry-immunofluorescence to conclude that LOXL2 plays an important role in promoting both glomerular and interstitial pathogenesis associated with Alport syndrome in mice.
Wed Aug 01 00:00:00 UTC 2018
Defective germline reprogramming rewires the spermatogonial transcriptome.
Nature structural & molecular biology
Vasiliauskaitė L,Berrens RV,Ivanova I,Carrieri C,Reik W,Enright AJ,O'Carroll D
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue May 01 00:00:00 UTC 2018
The E3 ligase VHL controls alveolar macrophage function via metabolic-epigenetic regulation.
The Journal of experimental medicine
Zhang W,Li Q,Li D,Li J,Aki D,Liu YC
14-0451 was used in Flow cytometry/Cell sorting to show VHL regulates alveolar macrophages and acts as a crucial egulatory factor in lung inflammation and fibrosis.
Mon Dec 03 00:00:00 UTC 2018
11 Beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis.
Journal of autoimmunity
Hardy RS,Fenton C,Croft AP,Naylor AJ,Begum R,Desanti G,Buckley CD,Lavery G,Cooper MS,Raza K
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Wed Aug 01 00:00:00 UTC 2018
Glucagon-like peptide 1 receptor signaling attenuates respiratory syncytial virus-induced type 2 responses and immunopathology.
The Journal of allergy and clinical immunology
Bloodworth MH,Rusznak M,Pfister CC,Zhang J,Bastarache L,Calvillo SA,Chappell JD,Boyd KL,Toki S,Newcomb DC,Stier MT,Zhou W,Goleniewska K,Moore ML,Hartert TV,Niswender KD,Peebles RS
14-0451 was used in Flow cytometry/Cell sorting to investigate the effect of activating the GLP-1R signalling pathway on mice mimicking severe respiratory infection.
Wed Aug 01 00:00:00 UTC 2018
Seed-induced Aβ deposition is modulated by microglia under environmental enrichment in a mouse model of Alzheimer's disease.
The EMBO journal
Ziegler-Waldkirch S,d'Errico P,Sauer JF,Erny D,Savanthrapadian S,Loreth D,Katzmarski N,Blank T,Bartos M,Prinz M,Meyer-Luehmann M
14-0451 was used in Flow cytometry/Cell sorting to study the impact and functional consequences of induced AB deposits on neurons in Alzheimer's disease.
Wed Jan 17 00:00:00 UTC 2018
Ex Vivo Selection of Transduced Hematopoietic Stem Cells for Gene Therapy of β-Hemoglobinopathies.
Molecular therapy : the journal of the American Society of Gene Therapy
Bhukhai K,de Dreuzy E,Giorgi M,Colomb C,Negre O,Denaro M,Gillet-Legrand B,Cheuzeville J,Paulard A,Trebeden-Negre H,Borwornpinyo S,Sii-Felice K,Maouche L,Down JD,Leboulch P,Payen E
14-0451 was used in Flow cytometry/Cell sorting to propose a procedure for complete selection and preservation of tranduced hematopoietic stem cells for human clinical applications.
Wed Feb 07 00:00:00 UTC 2018
Inhibition of the JNK/MAPK signaling pathway by myogenesis-associated miRNAs is required for skeletal muscle development.
Cell death and differentiation
Xie SJ,Li JH,Chen HF,Tan YY,Liu SR,Zhang Y,Xu H,Yang JH,Liu S,Zheng LL,Huang MB,Guo YH,Zhang Q,Zhou H,Qu LH
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Sat Sep 01 00:00:00 UTC 2018
Tumor-associated neutrophils suppress pro-tumoral IL-17+ γδ T cells through induction of oxidative stress.
PLoS biology
Mensurado S,Rei M,Lança T,Ioannou M,Gonçalves-Sousa N,Kubo H,Malissen M,Papayannopoulos V,Serre K,Silva-Santos B
14-0451 was used in Flow cytometry/Cell sorting to study the role of tumour-associated neutrophils in the regulation of γδ17 T-cell responses in the tumour microenvironment.
Tue May 01 00:00:00 UTC 2018
Humanized Mice Engrafted With Human HSC Only or HSC and Thymus Support Comparable HIV-1 Replication, Immunopathology, and Responses to ART and Immune Therapy.
Frontiers in immunology
Cheng L,Ma J,Li G,Su L
14-0451 was used in Flow cytometry/Cell sorting to report that NRG-hu Thy/HSC and NRG-hu HSC mice support similar HIV-1 infection and similar HIV-1 immunopathology; and HIV-1 replication responds similarly to cART and IFNAR blockade therapies.
Fri Jun 14 00:00:00 UTC 2019
Shared and independent functions of aPKCλ and Par3 in skin tumorigenesis.
Oncogene
Vorhagen S,Kleefisch D,Persa OD,Graband A,Schwickert A,Saynisch M,Leitges M,Niessen CM,Iden S
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunofluorescence
Sat Sep 01 00:00:00 UTC 2018
Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities.
The Journal of cell biology
Casey AE,Sinha A,Singhania R,Livingstone J,Waterhouse P,Tharmapalan P,Cruickshank J,Shehata M,Drysdale E,Fang H,Kim H,Isserlin R,Bailey S,Medina T,Deblois G,Shiah YJ,Barsyte-Lovejoy D,Hofer S,Bader G,Lupien M,Arrowsmith C,Knapp S,De Carvalho D,Berman H,Boutros PC,Kislinger T,Khokha R
14-0451 was used in Flow cytometry/Cell sorting to investigate the normal cell composition of the mammary epithelium by profiling primary cell epigenomes, transcriptomes and proteomes.
Mon Aug 06 00:00:00 UTC 2018
VISTA expression by microglia decreases during inflammation and is differentially regulated in CNS diseases.
Glia
Borggrewe M,Grit C,Den Dunnen WFA,Burm SM,Bajramovic JJ,Noelle RJ,Eggen BJL,Laman JD
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Sat Dec 01 00:00:00 UTC 2018
Protease-activated receptor-2 signaling through β-arrestin-2 mediates Alternaria alkaline serine protease-induced airway inflammation.
American journal of physiology. Lung cellular and molecular physiology
Yee MC,Nichols HL,Polley D,Saifeddine M,Pal K,Lee K,Wilson EH,Daines MO,Hollenberg MD,Boitano S,DeFea KA
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Sat Dec 01 00:00:00 UTC 2018
Prophylactic Antiheparanase Activity by PG545 Is Antiviral In Vitro and Protects against Ross River Virus Disease in Mice.
Antimicrobial agents and chemotherapy
Supramaniam A,Liu X,Ferro V,Herrero LJ
14-0451 was used in Flow cytometry/Cell sorting to describe both prophylactic and therapeutic treatment with PG545, a low-molecular-weight heparan sulfate mimetic, for arthritogenic alphaviral infection.
Sun Apr 01 00:00:00 UTC 2018
Choroidal pericytes promote subretinal fibrosis after experimental photocoagulation.
Disease models & mechanisms
Luo X,Yang S,Liang J,Zhai Y,Shen M,Sun J,Feng Y,Lu X,Zhu H,Wang F,Sun X
Mon Apr 23 00:00:00 UTC 2018
CCR7 on CD4+ T Cells Plays a Crucial Role in the Induction of Experimental Autoimmune Encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950)
Belikan P,Bühler U,Wolf C,Pramanik GK,Gollan R,Zipp F,Siffrin V
14-0451 was used in Flow cytometry/Cell sorting to indicate a crucial role of CCR7 in neuroinflammation during the priming of autoimmune CD4+ T cells but not in the CNS.
Sun Apr 15 00:00:00 UTC 2018
The Atypical Chemokine Receptor Ackr2 Constrains NK Cell Migratory Activity and Promotes Metastasis.
Journal of immunology (Baltimore, Md. : 1950)
Hansell CAH,Fraser AR,Hayes AJ,Pingen M,Burt CL,Lee KM,Medina-Ruiz L,Brownlie D,Macleod MKL,Burgoyne P,Wilson GJ,Nibbs RJB,Graham GJ
14-0451 was used in Flow cytometry/Cell sorting to determine the role of Ackr2 in metastasis.
Mon Oct 15 00:00:00 UTC 2018
MyD88 is required for satellite cell-mediated myofiber regeneration in dystrophin-deficient mdx mice.
Human molecular genetics
Gallot YS,Straughn AR,Bohnert KR,Xiong G,Hindi SM,Kumar A
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Oct 01 00:00:00 UTC 2018
Isolation of a unique hepatic stellate cell population expressing integrin α8 from embryonic mouse livers.
Developmental dynamics : an official publication of the American Association of Anatomists
Ogawa T,Li Y,Lua I,Hartner A,Asahina K
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunofluorescence
Fri Jun 01 00:00:00 UTC 2018
Simultaneous Inhibition of MEK and Hh Signaling Reduces Pancreatic Cancer Metastasis.
Cancers
Gu D,Lin H,Zhang X,Fan Q,Chen S,Shahda S,Liu Y,Sun J,Xie J
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Fri Oct 26 00:00:00 UTC 2018
Nur77 variants solely comprising the amino-terminal domain activate hypoxia-inducible factor-1α and affect bone marrow homeostasis in mice and humans.
The Journal of biological chemistry
Koenis DS,Medzikovic L,Vos M,Beldman TJ,van Loenen PB,van Tiel CM,Hamers AAJ,Otermin Rubio I,de Waard V,de Vries CJM
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Fri Sep 28 00:00:00 UTC 2018
Nur77 variants solely comprising the amino-terminal domain activate hypoxia-inducible factor-1α and affect bone marrow homeostasis in mice and humans.
The Journal of biological chemistry
Koenis DS,Medzikovic L,Vos M,Beldman TJ,van Loenen PB,van Tiel CM,Hamers AAJ,Otermin Rubio I,de Waard V,de Vries CJM
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Fri Sep 28 00:00:00 UTC 2018
A patient derived xenograft model of cervical cancer and cervical dysplasia.
PloS one
Larmour LI,Cousins FL,Teague JA,Deane JA,Jobling TW,Gargett CE
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunofluorescence
Fri Mar 29 00:00:00 UTC 2019
A patient derived xenograft model of cervical cancer and cervical dysplasia.
PloS one
Larmour LI,Cousins FL,Teague JA,Deane JA,Jobling TW,Gargett CE
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunofluorescence
Fri Mar 29 00:00:00 UTC 2019
MT4-MMP deficiency increases patrolling monocyte recruitment to early lesions and accelerates atherosclerosis.
Nature communications
Clemente C,Rius C,Alonso-Herranz L,Martín-Alonso M,Pollán Á,Camafeita E,Martínez F,Mota RA,Núñez V,Rodríguez C,Seiki M,Martínez-González J,Andrés V,Ricote M,Arroyo AG
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Mar 02 00:00:00 UTC 2018
mTOR Modulates CD8+ T Cell Differentiation in Mice with Invasive Pulmonary Aspergillosis.
Open life sciences
Wang H,Xiao Y,Su L,Cui N,Liu D
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Jan 01 00:00:00 UTC 2018
Lsd1 regulates skeletal muscle regeneration and directs the fate of satellite cells.
Nature communications
Tosic M,Allen A,Willmann D,Lepper C,Kim J,Duteil D,Schüle R
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Jan 25 00:00:00 UTC 2018
Diet-Induced Obesity Elicits Macrophage Infiltration and Reduction in Spine Density in the Hypothalami of Male but Not Female Mice.
Frontiers in immunology
Lainez NM,Jonak CR,Nair MG,Ethell IM,Wilson EH,Carson MJ,Coss D
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Wed Sep 25 00:00:00 UTC 2019
Adipocyte hypertrophy and lipid dynamics underlie mammary gland remodeling after lactation.
Nature communications
Zwick RK,Rudolph MC,Shook BA,Holtrup B,Roth E,Lei V,Van Keymeulen A,Seewaldt V,Kwei S,Wysolmerski J,Rodeheffer MS,Horsley V
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Sep 04 00:00:00 UTC 2018
ATF3 Sustains IL-22-Induced STAT3 Phosphorylation to Maintain Mucosal Immunity Through Inhibiting Phosphatases.
Frontiers in immunology
Glal D,Sudhakar JN,Lu HH,Liu MC,Chiang HY,Liu YC,Cheng CF,Shui JW
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Sep 26 00:00:00 UTC 2019
Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow.
Nature communications
Xu C,Gao X,Wei Q,Nakahara F,Zimmerman SE,Mar J,Frenette PS
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Jun 22 00:00:00 UTC 2018
Rap1 deficiency-provoked paracrine dysfunction impairs immunosuppressive potency of mesenchymal stem cells in allograft rejection of heart transplantation.
Cell death & disease
Ding Y,Liang X,Zhang Y,Yi L,Shum HC,Chen Q,Chan BP,Fan H,Liu Z,Tergaonkar V,Qi Z,Tse HF,Lian Q
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Wed Mar 07 00:00:00 UTC 2018
Partial depletion of CD206-positive M2-like macrophages induces proliferation of beige progenitors and enhances browning after cold stimulation.
Scientific reports
Igarashi Y,Nawaz A,Kado T,Bilal M,Kuwano T,Yamamoto S,Sasahara M,Jiuxiang X,Inujima A,Koizumi K,Imura J,Shibahara N,Usui I,Fujisaka S,Tobe K
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Oct 01 00:00:00 UTC 2018
CD157 Marks Tissue-Resident Endothelial Stem Cells with Homeostatic and Regenerative Properties.
Cell stem cell
Wakabayashi T,Naito H,Suehiro JI,Lin Y,Kawaji H,Iba T,Kouno T,Ishikawa-Kato S,Furuno M,Takara K,Muramatsu F,Weizhen J,Kidoya H,Ishihara K,Hayashizaki Y,Nishida K,Yoder MC,Takakura N
14-0451-82 was used in Flow cytometry/Cell sorting to show that tissue-resident VESCs display self-renewal capacity and that vascular regeneration potential exists in peripheral blood vessels.
Thu Mar 01 00:00:00 UTC 2018
Differential cytokine contributions of perivascular haematopoietic stem cell niches.
Nature cell biology
Asada N,Kunisaki Y,Pierce H,Wang Z,Fernandez NF,Birbrair A,Ma'ayan A,Frenette PS
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Wed Mar 01 00:00:00 UTC 2017
A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.
The Journal of clinical investigation
Berlato C,Khan MN,Schioppa T,Thompson R,Maniati E,Montfort A,Jangani M,Canosa M,Kulbe H,Hagemann UB,Duncan AR,Fletcher L,Wilkinson RW,Powles T,Quezada SA,Balkwill FR
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Wed Mar 01 00:00:00 UTC 2017
Impaired SUMOylation of nuclear receptor LRH-1 promotes nonalcoholic fatty liver disease.
The Journal of clinical investigation
Stein S,Lemos V,Xu P,Demagny H,Wang X,Ryu D,Jimenez V,Bosch F,Lüscher TF,Oosterveer MH,Schoonjans K
14-0451 was used in Immunohistochemistry to suggest that compromised SUMOylation of LRH-1 promotes the development of NAFLD under lipogenic conditions through regulation of OSBPL3.
Wed Feb 01 00:00:00 UTC 2017
Bispecific antibody targets multiple Pseudomonas aeruginosa evasion mechanisms in the lung vasculature.
The Journal of clinical investigation
Thanabalasuriar A,Surewaard BG,Willson ME,Neupane AS,Stover CK,Warrener P,Wilson G,Keller AE,Sellman BR,DiGiandomenico A,Kubes P
14-0451 was used in Flow cytometry/Cell sorting to highlight the need to block multiple evasion and subversion mechanisms in tandem to kill P. aeruginosa.
Thu Jun 01 00:00:00 UTC 2017
TGF-β1 modulates microglial phenotype and promotes recovery after intracerebral hemorrhage.
The Journal of clinical investigation
Taylor RA,Chang CF,Goods BA,Hammond MD,Mac Grory B,Ai Y,Steinschneider AF,Renfroe SC,Askenase MH,McCullough LD,Kasner SE,Mullen MT,Hafler DA,Love JC,Sansing LH
14-0451 was used in Flow cytometry/Cell sorting to investigate the specific responses of microglia following intracerebral haemorrhage with the aim of identifying pathways that may aid in recovery after brain injury.
Tue Jan 03 00:00:00 UTC 2017
Mast cells acquire MHCII from dendritic cells during skin inflammation.
The Journal of experimental medicine
Dudeck J,Medyukhina A,Fröbel J,Svensson CM,Kotrba J,Gerlach M,Gradtke AC,Schröder B,Speier S,Figge MT,Dudeck A
14-0451 was used in Flow cytometry/Cell sorting to identify an innate intercellular communication arming resident mast cells with key dendritic cell(DC) functions that might contribute to the acute defence potential during critical periods of migration-based DC absence.
Mon Dec 04 00:00:00 UTC 2017
Oncolytic Adenovirus and Tumor-Targeting Immune Modulatory Therapy Improve Autologous Cancer Vaccination.
Cancer research
Jiang H,Rivera-Molina Y,Gomez-Manzano C,Clise-Dwyer K,Bover L,Vence LM,Yuan Y,Lang FF,Toniatti C,Hossain MB,Fueyo J
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Sat Jul 15 00:00:00 UTC 2017
Sigma-1 receptors control immune-driven peripheral opioid analgesia during inflammation in mice.
Proceedings of the National Academy of Sciences of the United States of America
Tejada MA,Montilla-García A,Cronin SJ,Cikes D,Sánchez-Fernández C,González-Cano R,Ruiz-Cantero MC,Penninger JM,Vela JM,Baeyens JM,Cobos EJ
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Aug 01 00:00:00 UTC 2017
CD73 regulates anti-inflammatory signaling between apoptotic cells and endotoxin-conditioned tissue macrophages.
Cell death and differentiation
Murphy PS,Wang J,Bhagwat SP,Munger JC,Janssen WJ,Wright TW,Elliott MR
14-0451 was used in Flow cytometry/Cell sorting to show that, in RAW264.7 cells, ectopic expression of both A2a and CD73 was required for TNF suppression by apoptotic cells.
Wed Mar 01 00:00:00 UTC 2017
DNA damage and senescence in osteoprogenitors expressing Osx1 may cause their decrease with age.
Aging cell
Kim HN,Chang J,Shao L,Han L,Iyer S,Manolagas SC,O'Brien CA,Jilka RL,Zhou D,Almeida M
Tue Aug 01 00:00:00 UTC 2017
Obesity reversibly depletes the basal cell population and enhances mammary epithelial cell estrogen receptor alpha expression and progenitor activity.
Breast cancer research : BCR
Chamberlin T,D'Amato JV,Arendt LM
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Wed Nov 29 00:00:00 UTC 2017
Early IL-6 signalling promotes IL-27 dependent maturation of regulatory T cells in the lungs and resolution of viral immunopathology.
PLoS pathogens
Pyle CJ,Uwadiae FI,Swieboda DP,Harker JA
14-0451-82 was used in Flow Cytometry to show that during respiratory virus infection the prototypic inflammatory cytokine IL-6 is a critical anti-inflammatory regulator of viral induced immunopathology in the respiratory tract through its induction of IL-27.
Fri Sep 01 00:00:00 UTC 2017
Depletion of microglia exacerbates postischemic inflammation and brain injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Jin WN,Shi SX,Li Z,Li M,Wood K,Gonzales RJ,Liu Q
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Jun 01 00:00:00 UTC 2017
An atypical role for the myeloid receptor Mincle in central nervous system injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Arumugam TV,Manzanero S,Furtado M,Biggins PJ,Hsieh YH,Gelderblom M,MacDonald KP,Salimova E,Li YI,Korn O,Dewar D,Macrae IM,Ashman RB,Tang SC,Rosenthal NA,Ruitenberg MJ,Magnus T,Wells CA
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Jun 01 00:00:00 UTC 2017
Role of Triggering Receptor Expressed on Myeloid Cell-1 Expression in Mammalian Target of Rapamycin Modulation of CD8+ T-cell Differentiation during the Immune Response to Invasive Pulmonary Aspergillosis.
Chinese medical journal
Cui N,Wang H,Su LX,Zhang JH,Long Y,Liu DW
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Sat May 20 00:00:00 UTC 2017
Cornea lymphatics drive the CD8+ T-cell response to herpes simplex virus-1.
Immunology and cell biology
Gurung HR,Carr MM,Carr DJ
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Sun Jan 01 00:00:00 UTC 2017
Dimethyl fumarate treatment after traumatic brain injury prevents depletion of antioxidative brain glutathione and confers neuroprotection.
Journal of neurochemistry
Krämer T,Grob T,Menzel L,Hirnet T,Griemert E,Radyushkin K,Thal SC,Methner A,Schaefer MKE
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Fri Dec 01 00:00:00 UTC 2017
Cytochrome P450 26A1 modulates natural killer cells in mouse early pregnancy.
Journal of cellular and molecular medicine
Meng CY,Li ZY,Fang WN,Song ZH,Yang DD,Li DD,Yang Y,Peng JP
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Sat Apr 01 00:00:00 UTC 2017
β3-Adrenergic Regulation of EPC Features Through Manipulation of the Bone Marrow MSC Niche.
Journal of cellular biochemistry
Vafaei R,Nassiri SM,Siavashi V
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Dec 01 00:00:00 UTC 2017
The common parasite Toxoplasma gondii induces prostatic inflammation and microglandular hyperplasia in a mouse model.
The Prostate
Colinot DL,Garbuz T,Bosland MC,Wang L,Rice SE,Sullivan WJ,Arrizabalaga G,Jerde TJ
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Sat Jul 01 00:00:00 UTC 2017
Reduced Expression of VAMP8 in Lacrimal Gland Affected by Chronic Graft-versus-Host Disease.
Journal of ophthalmology
Fukui M,Ogawa Y,Mukai S,Kamoi M,Asato T,Kawakami Y,Tsubota K
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunofluorescence
Thu Mar 10 00:00:00 UTC 2022
Heavy Chain-Hyaluronan/Pentraxin 3 from Amniotic Membrane Suppresses Inflammation and Scarring in Murine Lacrimal Gland and Conjunctiva of Chronic Graft-versus-Host Disease.
Scientific reports
Ogawa Y,He H,Mukai S,Imada T,Nakamura S,Su CW,Mahabole M,Tseng SC,Tsubota K
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Mon Feb 06 00:00:00 UTC 2017
The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration.
eLife
Xiong G,Hindi SM,Mann AK,Gallot YS,Bohnert KR,Cavener DR,Whittemore SR,Kumar A
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Mar 23 00:00:00 UTC 2017
Blocking CTLA-4 while priming with a whole cell vaccine reshapes the oligoclonal T cell infiltrate and eradicates tumors in an orthotopic glioma model.
Oncoimmunology
Field CS,Hunn MK,Ferguson PM,Ruedl C,Ancelet LR,Hermans IF
14-0451 was used in Flow cytometry/Cell sorting to study the effect of the checkpoint blockade on the efficacy of responses induced with a whole tumour-cell vaccine.
Tue Jan 12 00:00:00 UTC 2021
microRNA-449a modulates medullary thymic epithelial cell differentiation.
Scientific reports
Chen P,Zhang H,Sun X,Hu Y,Jiang W,Liu Z,Liu S,Zhang X
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Nov 21 00:00:00 UTC 2017
Tristetraprolin expression by keratinocytes controls local and systemic inflammation.
JCI insight
Andrianne M,Assabban A,La C,Mogilenko D,Salle DS,Fleury S,Doumont G,Van Simaeys G,Nedospasov SA,Blackshear PJ,Dombrowicz D,Goriely S,Van Maele L
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Jun 02 00:00:00 UTC 2017
The Interleukin (IL)-1R1 pathway is a critical negative regulator of PyMT-mediated mammary tumorigenesis and pulmonary metastasis.
Oncoimmunology
Dagenais M,Dupaul-Chicoine J,Douglas T,Champagne C,Morizot A,Saleh M
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Jan 12 00:00:00 UTC 2021
Zoledronate suppressed angiogenesis and osteogenesis by inhibiting osteoclasts formation and secretion of PDGF-BB.
PloS one
Gao SY,Zheng GS,Wang L,Liang YJ,Zhang SE,Lao XM,Li K,Liao GQ
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Sep 18 00:00:00 UTC 2017
Irgm1 coordinately regulates autoimmunity and host defense at select mucosal surfaces.
JCI insight
Azzam KM,Madenspacher JH,Cain DW,Lai L,Gowdy KM,Rai P,Janardhan K,Clayton N,Cunningham W,Jensen H,Patel PS,Kearney JF,Taylor GA,Fessler MB
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Aug 17 00:00:00 UTC 2017
Cardiosphere-Derived Cells Require Endoglin for Paracrine-Mediated Angiogenesis.
Stem cell reports
Redgrave RE,Tual-Chalot S,Davison BJ,Singh E,Hall D,Amirrasouli MM,Gilchrist D,Medvinsky A,Arthur HM
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue May 09 00:00:00 UTC 2017
Acute inflammation regulates neuroregeneration through the NF-κB pathway in olfactory epithelium.
Proceedings of the National Academy of Sciences of the United States of America
Chen M,Reed RR,Lane AP
14-0451-82 was used in Immunohistochemistry-immunofluorescence to show that the repair of neuroepithelium after lesioning is accompanied by an acute, but self-limited, inflammatory process.
Tue Jul 25 00:00:00 UTC 2017
An asthma-associated IL4R variant exacerbates airway inflammation by promoting conversion of regulatory T cells to TH17-like cells.
Nature medicine
Massoud AH,Charbonnier LM,Lopez D,Pellegrini M,Phipatanakul W,Chatila TA
14-0451 was used in Flow cytometry/Cell sorting to identify a previously unknown mechanism for the development of TH17 cell inflammation in genetically prone individuals.
Thu Sep 01 00:00:00 UTC 2016
The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity.
Cell
Moroishi T,Hayashi T,Pan WW,Fujita Y,Holt MV,Qin J,Carson DA,Guan KL
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunofluorescence
Thu Dec 01 00:00:00 UTC 2016
Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation.
Nature immunology
Monticelli LA,Buck MD,Flamar AL,Saenz SA,Tait Wojno ED,Yudanin NA,Osborne LC,Hepworth MR,Tran SV,Rodewald HR,Shah H,Cross JR,Diamond JM,Cantu E,Christie JD,Pearce EL,Artis D
14-0451 was used in Flow cytometry/Cell sorting to identify Arg1 as a key regulator of group 2 innate lymphoid cell bioenergetics that control proliferative capacity and pro-inflammatory functions.
Wed Jun 01 00:00:00 UTC 2016
Classical dendritic cells are required for dietary antigen-mediated induction of peripheral T(reg) cells and tolerance.
Nature immunology
Esterházy D,Loschko J,London M,Jove V,Oliveira TY,Mucida D
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Sun May 01 00:00:00 UTC 2016
Oligodendrocyte death results in immune-mediated CNS demyelination.
Nature neuroscience
Traka M,Podojil JR,McCarthy DP,Miller SD,Popko B
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Jan 01 00:00:00 UTC 2016
Tissue-Specific Cell Cycle Indicator Reveals Unexpected Findings for Cardiac Myocyte Proliferation.
Circulation research
Hirai M,Chen J,Evans SM
14-0451 was used in Immunohistochemistry to highlight advantages of a cardiac myocyte-specific cell cycle reporter for studies of cardiac myocyte cell cycle regulation.
Fri Jan 08 00:00:00 UTC 2016
The breast tumor microenvironment alters the phenotype and function of natural killer cells.
Cellular & molecular immunology
Krneta T,Gillgrass A,Chew M,Ashkar AA
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Sep 01 00:00:00 UTC 2016
Inhibition of SHP2 ameliorates the pathogenesis of systemic lupus erythematosus.
The Journal of clinical investigation
Wang J,Mizui M,Zeng LF,Bronson R,Finnell M,Terhorst C,Kyttaris VC,Tsokos GC,Zhang ZY,Kontaridis MI
14-0451 was used in Flow cytometry/Cell sorting to explore the effect of inhibiting SHP2 on T cell activation, ERK/MAPK signalling and the production of cytokines associated with organ damage in sufferers of systemic lupus erythematosus.
Wed Jun 01 00:00:00 UTC 2016
Non-Cell-Autonomous Regulation of Prostate Epithelial Homeostasis by Androgen Receptor.
Molecular cell
Zhang B,Kwon OJ,Henry G,Malewska A,Wei X,Zhang L,Brinkley W,Zhang Y,Castro PD,Titus M,Chen R,Sayeeduddin M,Raj GV,Mauck R,Roehrborn C,Creighton CJ,Strand DW,Ittmann MM,Xin L
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Sep 15 00:00:00 UTC 2016
Endothelin A receptor activation on mesangial cells initiates Alport glomerular disease.
Kidney international
Dufek B,Meehan DT,Delimont D,Cheung L,Gratton MA,Phillips G,Song W,Liu S,Cosgrove D
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunofluorescence
Mon Aug 01 00:00:00 UTC 2016
Lymphatic Contribution to the Cellular Niche in Heterotopic Ossification.
Annals of surgery
Loder S,Agarwal S,Sorkin M,Breuler C,Li J,Peterson J,Gardenier J,Hsieh HH,Wang SC,Mehrara BJ,Levi B
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Dec 01 00:00:00 UTC 2016
Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America
Nishio M,Sugimachi K,Goto H,Wang J,Morikawa T,Miyachi Y,Takano Y,Hikasa H,Itoh T,Suzuki SO,Kurihara H,Aishima S,Leask A,Sasaki T,Nakano T,Nishina H,Nishikawa Y,Sekido Y,Nakao K,Shin-Ya K,Mimori K,Suzuki A
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunofluorescence
Tue Jan 05 00:00:00 UTC 2016
Overexpression of PIK3CA in murine head and neck epithelium drives tumor invasion and metastasis through PDK1 and enhanced TGFβ signaling.
Oncogene
Du L,Chen X,Cao Y,Lu L,Zhang F,Bornstein S,Li Y,Owens P,Malkoski S,Said S,Jin F,Kulesz-Martin M,Gross N,Wang XJ,Lu SL
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Thu Sep 01 00:00:00 UTC 2016
Group 2 innate lymphoid cells utilize the IRF4-IL-9 module to coordinate epithelial cell maintenance of lung homeostasis.
Mucosal immunology
Mohapatra A,Van Dyken SJ,Schneider C,Nussbaum JC,Liang HE,Locksley RM
14-0451 was used in Flow cytometry/Cell sorting to study how ILC2s link alveolar function to regulation of airway flow, revealing a key interaction between resident lymphoid and structural cells that might underlie similar organisational hierarchies in other organs.
Fri Jan 01 00:00:00 UTC 2016
CD11c(+) monocyte/macrophages promote chronic Helicobacter hepaticus-induced intestinal inflammation through the production of IL-23.
Mucosal immunology
Arnold IC,Mathisen S,Schulthess J,Danne C,Hegazy AN,Powrie F
14-0451 was used in Flow cytometry/Cell sorting to investigate the mechanism by which IL-23 produced by CD11c+ monocytes/macrophages promotes chronic Helicobacter hepaticus-induced intestinal inflammation.
Tue Mar 01 00:00:00 UTC 2016
IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid.
PLoS pathogens
Naujoks J,Tabeling C,Dill BD,Hoffmann C,Brown AS,Kunze M,Kempa S,Peter A,Mollenkopf HJ,Dorhoi A,Kershaw O,Gruber AD,Sander LE,Witzenrath M,Herold S,Nerlich A,Hocke AC,van Driel I,Suttorp N,Bedoui S,Hilbi H,Trost M,Opitz B
14-0451 was used in Flow cytometry/Cell sorting to explore the overall role IFNs play in inducing substantial remodeling of bacterial vacuoles and in stimulating production of IRG1-derived itaconic acid which targets intravacuolar pathogens.
Mon Feb 01 00:00:00 UTC 2016
The Mouse Cytomegalovirus Gene m42 Targets Surface Expression of the Protein Tyrosine Phosphatase CD45 in Infected Macrophages.
PLoS pathogens
Thiel N,Keyser KA,Lemmermann NA,Oduro JD,Wagner K,Elsner C,Halenius A,Lenac Roviš T,Brinkmann MM,Jonjić S,Cicin-Sain L,Messerle M
14-0451 was used in Flow cytometry/Cell sorting to demonstrate that the down-modulation of CD45 expression in MCMV-infected myeloid cells represents a novel pathway of virus-host interaction.
Thu Dec 01 00:00:00 UTC 2016
Dynamic spatio-temporal contribution of single β5t+ cortical epithelial precursors to the thymus medulla.
European journal of immunology
Mayer CE,Žuklys S,Zhanybekova S,Ohigashi I,Teh HY,Sansom SN,Shikama-Dorn N,Hafen K,Macaulay IC,Deadman ME,Ponting CP,Takahama Y,Holländer GA
14-0451 was used in Flow cytometry/Cell sorting to reveal the spatio-temporal dynamics that control the growth of the thymic medulla.
Fri Apr 01 00:00:00 UTC 2016
Analysis of Bone-Cartilage-Stromal Progenitor Populations in Trauma Induced and Genetic Models of Heterotopic Ossification.
Stem cells (Dayton, Ohio)
Agarwal S,Loder SJ,Sorkin M,Li S,Shrestha S,Zhao B,Mishina Y,James AW,Levi B
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Wed Jun 01 00:00:00 UTC 2016
Analysis of Bone-Cartilage-Stromal Progenitor Populations in Trauma Induced and Genetic Models of Heterotopic Ossification.
Stem cells (Dayton, Ohio)
Agarwal S,Loder SJ,Sorkin M,Li S,Shrestha S,Zhao B,Mishina Y,James AW,Levi B
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Wed Jun 01 00:00:00 UTC 2016
Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency.
Journal of immunology (Baltimore, Md. : 1950)
Menendez CM,Jinkins JK,Carr DJ
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Aug 15 00:00:00 UTC 2016
Regulatory T Cells Control Th2-Dominant Murine Autoimmune Gastritis.
Journal of immunology (Baltimore, Md. : 1950)
Harakal J,Rival C,Qiao H,Tung KS
14-0451-82 was used in Flow Cytometry to suggest that Tregs maintain physiological tolerance to clinically relevant gastric autoantigens, and Th2 responses can be a pathogenic mechanism in AIG.
Fri Jul 01 00:00:00 UTC 2016
Deletion of 5-Lipoxygenase in the Tumor Microenvironment Promotes Lung Cancer Progression and Metastasis through Regulating T Cell Recruitment.
Journal of immunology (Baltimore, Md. : 1950)
Poczobutt JM,Nguyen TT,Hanson D,Li H,Sippel TR,Weiser-Evans MC,Gijon M,Murphy RC,Nemenoff RA
14-0451 was used in Flow cytometry/Cell sorting to reveal an antitumorigenic role for 5-LO products in the microenvironment during lung cancer progression through T cell regulation.
Fri Jan 15 00:00:00 UTC 2016
ECM-Dependence of Endothelial Progenitor Cell Features.
Journal of cellular biochemistry
Siavashi V,Nassiri SM,Rahbarghazi R,Vafaei R,Sariri R
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Aug 01 00:00:00 UTC 2016
Effects of nerve growth factor and basic fibroblast growth factor dual gene modification on rat bone marrow mesenchymal stem cell differentiation into neuron-like cells in vitro.
Molecular medicine reports
Hu Y,Zhang Y,Tian K,Xun C,Wang S,Lv D
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Jan 01 00:00:00 UTC 2016
A flow cytometric approach to analyzing mature and progenitor endothelial cells following traumatic brain injury.
Journal of neuroscience methods
Assis-Nascimento P,Umland O,Cepero ML,Liebl DJ
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Apr 01 00:00:00 UTC 2016
Heterogeneous fibroblasts underlie age-dependent tertiary lymphoid tissues in the kidney.
JCI insight
Sato Y,Mii A,Hamazaki Y,Fujita H,Nakata H,Masuda K,Nishiyama S,Shibuya S,Haga H,Ogawa O,Shimizu A,Narumiya S,Kaisho T,Arita M,Yanagisawa M,Miyasaka M,Sharma K,Minato N,Kawamoto H,Yanagita M
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Thu Jul 21 00:00:00 UTC 2016
Heterogeneous fibroblasts underlie age-dependent tertiary lymphoid tissues in the kidney.
JCI insight
Sato Y,Mii A,Hamazaki Y,Fujita H,Nakata H,Masuda K,Nishiyama S,Shibuya S,Haga H,Ogawa O,Shimizu A,Narumiya S,Kaisho T,Arita M,Yanagisawa M,Miyasaka M,Sharma K,Minato N,Kawamoto H,Yanagita M
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Thu Jul 21 00:00:00 UTC 2016
A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis.
Nature communications
Jeric I,Maurer G,Cavallo AL,Raguz J,Desideri E,Tarkowski B,Parrini M,Fischer I,Zatloukal K,Baccarini M
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Wed Dec 21 00:00:00 UTC 2016
Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis.
Nature communications
Ruhland MK,Loza AJ,Capietto AH,Luo X,Knolhoff BL,Flanagan KC,Belt BA,Alspach E,Leahy K,Luo J,Schaffer A,Edwards JR,Longmore G,Faccio R,DeNardo DG,Stewart SA
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Wed Jun 08 00:00:00 UTC 2016
A New Mouse Model That Spontaneously Develops Chronic Liver Inflammation and Fibrosis.
PloS one
Fransén-Pettersson N,Duarte N,Nilsson J,Lundholm M,Mayans S,Larefalk Å,Hannibal TD,Hansen L,Schmidt-Christensen A,Ivars F,Cardell S,Palmqvist R,Rozell B,Holmberg D
14-0451 was used in Immunohistochemistry to establish a new mouse model which spontaneously develops progressive inflammation and fibrosis in multiple organs.
Mon Jul 24 00:00:00 UTC 2017
Brain trauma elicits non-canonical macrophage activation states.
Journal of neuroinflammation
Kim CC,Nakamura MC,Hsieh CL
14-0451 was used in Flow cytometry/Cell sorting to investigate the novel activation states involved in the early macrophage response to traumatic brain injury.
Tue May 24 00:00:00 UTC 2016
Targeting VEGF-A in myeloid cells enhances natural killer cell responses to chemotherapy and ameliorates cachexia.
Nature communications
Klose R,Krzywinska E,Castells M,Gotthardt D,Putz EM,Kantari-Mimoun C,Chikdene N,Meinecke AK,Schrödter K,Helfrich I,Fandrey J,Sexl V,Stockmann C
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Aug 19 00:00:00 UTC 2016
Proteomics analysis reveals a Th17-prone cell population in presymptomatic graft-versus-host disease.
JCI insight
Li W,Liu L,Gomez A,Zhang J,Ramadan A,Zhang Q,Choi SW,Zhang P,Greenson JK,Liu C,Jiang D,Virts E,Kelich SL,Chu HW,Flynn R,Blazar BR,Hanenberg H,Hanash S,Paczesny S
14-0451 was used in Flow cytometry/Cell sorting to discover an ICOS-stimulated, Th17-prone CD4(+)CD146(+)CCR5(+) T cell subset that may serve as an early gastrointestinal graft-versus-host-disease biomarker.
Thu May 05 00:00:00 UTC 2016
Requirement of Stat3 Signaling in the Postnatal Development of Thymic Medullary Epithelial Cells.
PLoS genetics
Satoh R,Kakugawa K,Yasuda T,Yoshida H,Sibilia M,Katsura Y,Levi B,Abramson J,Koseki Y,Koseki H,van Ewijk W,Hollander GA,Kawamoto H
14-0451 was used in Flow cytometry/Cell sorting to demonstrate that Stat3-mediated signals via EGF-R determine medullary thymic epithelial cell cellularity and architectural organisation, and hence the size of the medulla.
Fri Jan 01 00:00:00 UTC 2016
Vectorization in an oncolytic vaccinia virus of an antibody, a Fab and a scFv against programmed cell death -1 (PD-1) allows their intratumoral delivery and an improved tumor-growth inhibition.
Oncoimmunology
Kleinpeter P,Fend L,Thioudellet C,Geist M,Sfrontato N,Koerper V,Fahrner C,Schmitt D,Gantzer M,Remy-Ziller C,Brandely R,Villeval D,Rittner K,Silvestre N,Erbs P,Zitvogel L,Quéméneur E,Préville X,Marchand JB
14-0451 was used in Flow cytometry/Cell sorting to develop a method to vectorise a hamster monoclonal IgG against murine PD-1 in Western Reserve oncolytic vaccina virus.
Tue Jan 12 00:00:00 UTC 2021
Protein Kinase D2 Protects against Acute Colitis Induced by Dextran Sulfate Sodium in Mice.
Scientific reports
Xiong J,Zhou MF,Wang YD,Chen LP,Xu WF,Wang YD,Deng F,Liu SD
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Sep 23 00:00:00 UTC 2016
Loss of the Ubiquitin-conjugating Enzyme UBE2W Results in Susceptibility to Early Postnatal Lethality and Defects in Skin, Immune, and Male Reproductive Systems.
The Journal of biological chemistry
Wang B,Merillat SA,Vincent M,Huber AK,Basrur V,Mangelberger D,Zeng L,Elenitoba-Johnson K,Miller RA,Irani DN,Dlugosz AA,Schnell S,Scaglione KM,Paulson HL
14-0451 was used in Flow cytometry/Cell sorting to establish that UBE2W is an important protein for early postnatal survival and the normal functioning of multiple organ systems.
Fri Feb 05 00:00:00 UTC 2016
Stat3 Signaling Promotes Survival And Maintenance Of Medullary Thymic Epithelial Cells.
PLoS genetics
Lomada D,Jain M,Bolner M,Reeh KA,Kang R,Reddy MC,DiGiovanni J,Richie ER
14-0451 was used in Flow cytometry/Cell sorting to demonstrate that in addition to the NFkB pathway, Stat3-mediated signals play an essential role in regulating mTEC cellularity and medullary region homeostasis.
Fri Jan 01 00:00:00 UTC 2016
Preparation of Single Cell Suspensions from Mouse Aorta.
Bio-protocol
Hu D,Yin C,Mohanta SK,Weber C,Habenicht AJ
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Sun Jun 05 00:00:00 UTC 2016
Irradiation of necrotic cancer cells, employed for pulsing dendritic cells (DCs), potentiates DC vaccine-induced antitumor immunity against high-grade glioma.
Oncoimmunology
Vandenberk L,Garg AD,Verschuere T,Koks C,Belmans J,Beullens M,Agostinis P,De Vleeschouwer S,Van Gool SW
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Feb 01 00:00:00 UTC 2016
Trogocytosis-associated cell to cell spread of intracellular bacterial pathogens.
eLife
Steele S,Radlinski L,Taft-Benz S,Brunton J,Kawula TH
14-0451 was used in Flow cytometry/Cell sorting to study trogocytosis-associated cell to cell spread of intracellular bacterial pathogens.
Sat Jan 23 00:00:00 UTC 2016
Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine.
Scientific reports
Ochi T,Feng Y,Kitamoto S,Nagao-Kitamoto H,Kuffa P,Atarashi K,Honda K,Teitelbaum DH,Kamada N
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Wed Jun 15 00:00:00 UTC 2016
LTβR controls thymic portal endothelial cells for haematopoietic progenitor cell homing and T-cell regeneration.
Nature communications
Shi Y,Wu W,Chai Q,Li Q,Hou Y,Xia H,Ren B,Xu H,Guo X,Jin C,Lv M,Wang Z,Fu YX,Zhu M
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Aug 05 00:00:00 UTC 2016
Parent stem cells can serve as niches for their daughter cells.
Nature
Pardo-Saganta A,Tata PR,Law BM,Saez B,Chow RD,Prabhu M,Gridley T,Rajagopal J
14-0451 was used in Immunohistochemistry to describe a signalling relay from adult mammalian progenitor cells and reveal it to be necessary for daughter cell maintenance.
Thu Jul 30 00:00:00 UTC 2015
CXCR3 chemokine receptor enables local CD8(+) T cell migration for the destruction of virus-infected cells.
Immunity
Hickman HD,Reynoso GV,Ngudiankama BF,Cush SS,Gibbs J,Bennink JR,Yewdell JW
14-0451 was used in Flow cytometry/Cell sorting to investigate how CD8(+) T cells locate virus-infected cells within tissues, showing that the CXCR3 chemokine receptor enables migration for the destruction of virus-infected cells.
Tue Mar 17 00:00:00 UTC 2015
CXCR3 chemokine receptor enables local CD8(+) T cell migration for the destruction of virus-infected cells.
Immunity
Hickman HD,Reynoso GV,Ngudiankama BF,Cush SS,Gibbs J,Bennink JR,Yewdell JW
14-0451 was used in Flow cytometry/Cell sorting to investigate how CD8(+) T cells locate virus-infected cells within tissues, showing that the CXCR3 chemokine receptor enables migration for the destruction of virus-infected cells.
Tue Mar 17 00:00:00 UTC 2015
Inhibition of the TNF Family Cytokine RANKL Prevents Autoimmune Inflammation in the Central Nervous System.
Immunity
Guerrini MM,Okamoto K,Komatsu N,Sawa S,Danks L,Penninger JM,Nakashima T,Takayanagi H
14-0451-82 was used in Flow Cytometry to show that receptor activator of nuclear factor-κB (NF-κB) ligand (RANKL) on T cells regulates C-C type chemokine ligand 20 (CCL20) production by astrocytes and T cell localization in the CNS.
Tue Dec 15 00:00:00 UTC 2015
Host microbiota constantly control maturation and function of microglia in the CNS.
Nature neuroscience
Erny D,Hrabě de Angelis AL,Jaitin D,Wieghofer P,Staszewski O,David E,Keren-Shaul H,Mahlakoiv T,Jakobshagen K,Buch T,Schwierzeck V,Utermöhlen O,Chun E,Garrett WS,McCoy KD,Diefenbach A,Staeheli P,Stecher B,Amit I,Prinz M
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Wed Jul 01 00:00:00 UTC 2015
Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cells.
The Journal of clinical investigation
Gori JL,Butler JM,Chan YY,Chandrasekaran D,Poulos MG,Ginsberg M,Nolan DJ,Elemento O,Wood BL,Adair JE,Rafii S,Kiem HP
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Mar 02 00:00:00 UTC 2015
Neutrophil-related factors as biomarkers in EAE and MS.
The Journal of experimental medicine
Rumble JM,Huber AK,Krishnamoorthy G,Srinivasan A,Giles DA,Zhang X,Wang L,Segal BM
14-0451 was used in Flow cytometry/Cell sorting to provide evidence of neutrophil involvement in MS and the animal model EAE, and suggest neutrophil-related molecules as an alternative source of novel biomarkers and therapeutic targets in MS.
Mon Jan 12 00:00:00 UTC 2015
Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus.
EMBO molecular medicine
Herbst S,Shah A,Mazon Moya M,Marzola V,Jensen B,Reed A,Birrell MA,Saijo S,Mostowy S,Shaunak S,Armstrong-James D
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Sun Mar 01 00:00:00 UTC 2015
Curing mice with large tumors by locally delivering combinations of immunomodulatory antibodies.
Clinical cancer research : an official journal of the American Association for Cancer Research
Dai M,Yip YY,Hellstrom I,Hellstrom KE
14045182 was used in flow cytometry to test the efficacy of combining different monoclonal antibodies to treat cancer
Sun Mar 01 00:00:00 UTC 2015
β-catenin promotes regulatory T-cell responses in tumors by inducing vitamin A metabolism in dendritic cells.
Cancer research
Hong Y,Manoharan I,Suryawanshi A,Majumdar T,Angus-Hill ML,Koni PA,Manicassamy B,Mellor AL,Munn DH,Manicassamy S
14-0451 was used in Flow cytometry/Cell sorting to show that dendritic cells in the tumour microenvironment acquire the ability to metabolise vitamin A to produce retinoic acid, driving immune tolerance.
Sun Feb 15 00:00:00 UTC 2015
Tracking and Functional Characterization of Epithelial-Mesenchymal Transition and Mesenchymal Tumor Cells during Prostate Cancer Metastasis.
Cancer research
Ruscetti M,Quach B,Dadashian EL,Mulholland DJ,Wu H
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Wed Jul 01 00:00:00 UTC 2015
Atypical chemokine receptor 1 deficiency reduces atherogenesis in ApoE-knockout mice.
Cardiovascular research
Wan W,Liu Q,Lionakis MS,Marino AP,Anderson SA,Swamydas M,Murphy PM
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Jun 01 00:00:00 UTC 2015
The transcription factor ATF2 promotes melanoma metastasis by suppressing protein fucosylation.
Science signaling
Lau E,Feng Y,Claps G,Fukuda MN,Perlina A,Donn D,Jilaveanu L,Kluger H,Freeze HH,Ronai ZA
14-0451 was used in Immunofluorescence to study how inhibiting PKCε or ATF2 or increasing protein fucosylation in tumor cells may improve clinical outcome in melanoma patients.
Tue Dec 08 00:00:00 UTC 2015
Brahma is required for cell cycle arrest and late muscle gene expression during skeletal myogenesis.
EMBO reports
Albini S,Coutinho Toto P,Dall'Agnese A,Malecova B,Cenciarelli C,Felsani A,Caruso M,Bultman SJ,Puri PL
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunofluorescence
Sat Aug 01 00:00:00 UTC 2015
The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma.
eLife
Krah NM,De La O JP,Swift GH,Hoang CQ,Willet SG,Chen Pan F,Cash GM,Bronner MP,Wright CV,MacDonald RJ,Murtaugh LC
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunofluorescence
Tue Jul 07 00:00:00 UTC 2015
Transcription factor c-Rel plays a crucial role in driving anti-CD40-mediated innate colitis.
Mucosal immunology
Visekruna A,Linnerz T,Martinic V,Vachharajani N,Hartmann S,Harb H,Joeris T,Pfefferle PI,Hofer MJ,Steinhoff U
14-0451 was used in Flow cytometry/Cell sorting to investigate the role c-Rel plays in regulating innate lymphoid cells which induce anti-CD40-mediated innate colitis in mice.
Sun Mar 01 00:00:00 UTC 2015
IL-1β in eosinophil-mediated small intestinal homeostasis and IgA production.
Mucosal immunology
Jung Y,Wen T,Mingler MK,Caldwell JM,Wang YH,Chaplin DD,Lee EH,Jang MH,Woo SY,Seoh JY,Miyasaka M,Rothenberg ME
14-0451 was used in Flow cytometry/Cell sorting to show that eosinophils are required for mucosal production of IgA and development of Peyer's patches in the gut.
Wed Jul 01 00:00:00 UTC 2015
Commensal enteric bacteria lipopolysaccharide impairs host defense against disseminated Candida albicans fungal infection.
Mucosal immunology
Jiang TT,Chaturvedi V,Ertelt JM,Xin L,Clark DR,Kinder JM,Way SS
14-0451 was used in Flow cytometry/Cell sorting to study susceptibility against Candida albicans fungal infectiong following eradication of commensal enteric bacteria, showing loss of commensal bacteria enhances antifungal immunity through robust systemic expansion of Ly6G(hi)Ly6C(int) neutrophils, suggesting that enteric bacteria restrains activation of some immune components.
Wed Jul 01 00:00:00 UTC 2015
Transcriptional Pathways in cPGI2-Induced Adipocyte Progenitor Activation for Browning.
Frontiers in endocrinology
Bayindir I,Babaeikelishomi R,Kocanova S,Sousa IS,Lerch S,Hardt O,Wild S,Bosio A,Bystricky K,Herzig S,Vegiopoulos A
14-0451 was used in Flow cytometry/Cell sorting to develop models for the mechanistic investigation of progenitor-mediated beige/brite adipocyte differentiation.
Tue Sep 08 00:00:00 UTC 2015
Dendritic Cell-Based Vaccines that Utilize Myeloid Rather than Plasmacytoid Cells Offer a Superior Survival Advantage in Malignant Glioma.
Journal of immunology (Baltimore, Md. : 1950)
Dey M,Chang AL,Miska J,Wainwright DA,Ahmed AU,Balyasnikova IV,Pytel P,Han Y,Tobias A,Zhang L,Qiao J,Lesniak MS
14-0451 was used in Flow cytometry/Cell sorting to compare the ability of myeloid and plasmacytoid dendritic cells to generate effective antiglioma immunity.
Wed Jul 01 00:00:00 UTC 2015
Ly6C(high) monocytes control cerebral toxoplasmosis.
Journal of immunology (Baltimore, Md. : 1950)
Biswas A,Bruder D,Wolf SA,Jeron A,Mack M,Heimesaat MM,Dunay IR
14-0451 was used in Flow cytometry/Cell sorting to indicate the critical importance of recruited Ly6C monocytes upon cerebral toxoplasmosis.
Wed Apr 01 00:00:00 UTC 2015
Cutting edge: NF-κB p65 and c-Rel control epidermal development and immune homeostasis in the skin.
Journal of immunology (Baltimore, Md. : 1950)
Grinberg-Bleyer Y,Dainichi T,Oh H,Heise N,Klein U,Schmid RM,Hayden MS,Ghosh S
14-0451-82 was used in Flow Cytometry to analyse the function of canonical NF-κB in the epidermis using CRE-mediated deletion of p65 and c-Rel in keratinocytes.
Sun Mar 15 00:00:00 UTC 2015
Canonical wnt signaling in dendritic cells regulates Th1/Th17 responses and suppresses autoimmune neuroinflammation.
Journal of immunology (Baltimore, Md. : 1950)
Suryawanshi A,Manoharan I,Hong Y,Swafford D,Majumdar T,Taketo MM,Manicassamy B,Koni PA,Thangaraju M,Sun Z,Mellor AL,Munn DH,Manicassamy S
14-0451 was used in Flow cytometry/Cell sorting to study the factors in the tissue microenvironment and signalling networks critical for programming dendritic cells to control chronic inflammation and promote tolerance, showing that Th1/Th17 responses are regulated by canonical Wnt signalling in dendritic cells and suppresses autoimmune neuroinflammation.
Wed Apr 01 00:00:00 UTC 2015
Inhibition of System Xc(-) Transporter Attenuates Autoimmune Inflammatory Demyelination.
Journal of immunology (Baltimore, Md. : 1950)
Evonuk KS,Baker BJ,Doyle RE,Moseley CE,Sestero CM,Johnston BP,De Sarno P,Tang A,Gembitsky I,Hewett SJ,Weaver CT,Raman C,DeSilva TM
14-0451 was used in Flow cytometry/Cell sorting to investigate the link between inflammation and glutamate dysregulation in EAE, showing that inhibition of system Xc(-) transporter attenuates autoimmune inflammatory demyelination.
Wed Jul 15 00:00:00 UTC 2015
Conditional immortalization of primary adipocyte precursor cells.
Adipocyte
Church C,Brown M,Rodeheffer MS
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Aug 10 00:00:00 UTC 2015
Nonadherent culture method downregulates stem cell antigen-1 expression in mouse bone marrow mesenchymal stem cells.
Experimental and therapeutic medicine
Deng B,Deng W,Xiao P,Zeng K,Zhang S,Zhang H,Deng DY,Yang Y
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Wed Jul 01 00:00:00 UTC 2015
Endothelial Gata5 transcription factor regulates blood pressure.
Nature communications
Messaoudi S,He Y,Gutsol A,Wight A,Hébert RL,Vilmundarson RO,Makrigiannis AP,Chalmers J,Hamet P,Tremblay J,McPherson R,Stewart AFR,Touyz RM,Nemer M
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Nov 30 00:00:00 UTC 2015
Endothelial Gata5 transcription factor regulates blood pressure.
Nature communications
Messaoudi S,He Y,Gutsol A,Wight A,Hébert RL,Vilmundarson RO,Makrigiannis AP,Chalmers J,Hamet P,Tremblay J,McPherson R,Stewart AFR,Touyz RM,Nemer M
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Nov 30 00:00:00 UTC 2015
Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors.
PloS one
Tähtinen S,Kaikkonen S,Merisalo-Soikkeli M,Grönberg-Vähä-Koskela S,Kanerva A,Parviainen S,Vähä-Koskela M,Hemminki A
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Apr 28 00:00:00 UTC 2016
Doxil synergizes with cancer immunotherapies to enhance antitumor responses in syngeneic mouse models.
Neoplasia (New York, N.Y.)
Rios-Doria J,Durham N,Wetzel L,Rothstein R,Chesebrough J,Holoweckyj N,Zhao W,Leow CC,Hollingsworth R
14-0451 was used in Flow cytometry/Cell sorting to investigate the ability of doxorubicin and liposomal doxorubicin to enhance the antitumor response of different cancer immunotherapies in mouse models.
Sat Aug 01 00:00:00 UTC 2015
Distinct in vitro properties of embryonic and extraembryonic fibroblast-like cells are reflected in their in vivo behavior following grafting in the adult mouse brain.
Cell transplantation
Costa R,Bergwerf I,Santermans E,De Vocht N,Praet J,Daans J,Le Blon D,Hoornaert C,Reekmans K,Hens N,Goossens H,Berneman Z,Parolini O,Alviano F,Ponsaerts P
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Nov 16 00:00:00 UTC 2015
Aberrant activation of NF-κB signaling in mammary epithelium leads to abnormal growth and ductal carcinoma in situ.
BMC cancer
Barham W,Chen L,Tikhomirov O,Onishko H,Gleaves L,Stricker TP,Blackwell TS,Yull FE
14-0451 was used in Flow cytometry/Cell sorting to determine if activation of NF-κB in mammary epithelium could play a role in the formation of hyperplastic ductal lesions.
Wed Sep 30 00:00:00 UTC 2015
Evaluation of the BDCA2-DTR Transgenic Mouse Model in Chronic and Acute Inflammation.
PloS one
Mandl M,Drechsler M,Jansen Y,Neideck C,Noels H,Faussner A,Soehnlein O,Weber C,Döring Y
14-0451 was used in Flow cytometry/Cell sorting to investigate how continuous diphtheria toxin-induced pDC depletion in Apoe-/- BDCA2-DTR mice receiving a high-fat diet (HFD) for 4 weeks did not alter lesion size or composition.
Sun May 08 00:00:00 UTC 2016
The Nuclear Orphan Receptor NR2F6 Is a Central Checkpoint for Cancer Immune Surveillance.
Cell reports
Hermann-Kleiter N,Klepsch V,Wallner S,Siegmund K,Klepsch S,Tuzlak S,Villunger A,Kaminski S,Pfeifhofer-Obermair C,Gruber T,Wolf D,Baier G
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Sep 29 00:00:00 UTC 2015
Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1.
PloS one
Szulzewsky F,Pelz A,Feng X,Synowitz M,Markovic D,Langmann T,Holtman IR,Wang X,Eggen BJ,Boddeke HW,Hambardzumyan D,Wolf SA,Kettenmann H
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Jan 12 00:00:00 UTC 2016
CCR7-dependent trafficking of RORγ⁺ ILCs creates a unique microenvironment within mucosal draining lymph nodes.
Nature communications
Mackley EC,Houston S,Marriott CL,Halford EE,Lucas B,Cerovic V,Filbey KJ,Maizels RM,Hepworth MR,Sonnenberg GF,Milling S,Withers DR
14-0451 was used in Flow cytometry/Cell sorting to investigate whether group 3 innate lymphoid cells migrate from their mucosal and peripheral sites to local draining secondary lymphoid tissues.
Fri Jan 09 00:00:00 UTC 2015
Targeted Gene Correction in Osteopetrotic-Induced Pluripotent Stem Cells for the Generation of Functional Osteoclasts.
Stem cell reports
Neri T,Muggeo S,Paulis M,Caldana ME,Crisafulli L,Strina D,Focarelli ML,Faggioli F,Recordati C,Scaramuzza S,Scanziani E,Mantero S,Buracchi C,Sobacchi C,Lombardo A,Naldini L,Vezzoni P,Villa A,Ficara F
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Oct 13 00:00:00 UTC 2015
Cardiac telocytes and fibroblasts in primary culture: different morphologies and immunophenotypes.
PloS one
Bei Y,Zhou Q,Fu S,Lv D,Chen P,Chen Y,Wang F,Xiao J
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Wed Nov 11 00:00:00 UTC 2015
Deficient Natural Killer Dendritic Cell Responses Underlay the Induction of Theiler's Virus-Induced Autoimmunity.
mBio
Chastain EM,Getts DR,Miller SD
14-0451 was used in Flow cytometry/Cell sorting to determine that disease-susceptible SJL/J mice lacked a unique innate immune population, which plays a role in early CNS virus clearance.
Tue Aug 04 00:00:00 UTC 2015
Galectin-3 deficiency exacerbates hyperglycemia and the endothelial response to diabetes.
Cardiovascular diabetology
Darrow AL,Shohet RV
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Sat Jun 06 00:00:00 UTC 2015
Diet and specific microbial exposure trigger features of environmental enteropathy in a novel murine model.
Nature communications
Brown EM,Wlodarska M,Willing BP,Vonaesch P,Han J,Reynolds LA,Arrieta MC,Uhrig M,Scholz R,Partida O,Borchers CH,Sansonetti PJ,Finlay BB
14-0451 was used in Flow cytometry/Cell sorting to provide evidence indicating that both diet and microbes combine to contribute to the aetiology of environmental enteropathy.
Tue Aug 04 00:00:00 UTC 2015
Roles of lymphatic endothelial cells expressing peripheral tissue antigens in CD4 T-cell tolerance induction.
Nature communications
Rouhani SJ,Eccles JD,Riccardi P,Peske JD,Tewalt EF,Cohen JN,Liblau R,Mäkinen T,Engelhard VH
14-0451 was used in Flow cytometry/Cell sorting to demonstrate that when β-galactosidase (β-gal) is expressed in LECs, β-gal-specific CD8 T cells undergo deletion via the PD-1/PD-L1 and LAG-3/MHC-II pathways.
Fri Apr 10 00:00:00 UTC 2015
Conditional overexpression of TGFβ1 promotes pulmonary inflammation, apoptosis and mortality via TGFβR2 in the developing mouse lung.
Respiratory research
Sureshbabu A,Syed MA,Boddupalli CS,Dhodapkar MV,Homer RJ,Minoo P,Bhandari V
14-0451 was used in Flow cytometry/Cell sorting to investigate the mechanisms responsible for TGFβ1-induced inflammatory signals leading to abnormal alveolarization, showing that it promotes pulmonary inflammation, apoptosis and mortality via TGFβR2.
Fri Jan 16 00:00:00 UTC 2015
Multi-spectral fluorescent reporter influenza viruses (Color-flu) as powerful tools for in vivo studies.
Nature communications
Fukuyama S,Katsura H,Zhao D,Ozawa M,Ando T,Shoemaker JE,Ishikawa I,Yamada S,Neumann G,Watanabe S,Kitano H,Kawaoka Y
14-0451 was used in Flow cytometry/Cell sorting to investigate influenza pathogenesis using influenza viruses expressing fluorescent proteins of different colours.
Wed Mar 25 00:00:00 UTC 2015
Reprogramming human endothelial cells to haematopoietic cells requires vascular induction.
Nature
Sandler VM,Lis R,Liu Y,Kedem A,James D,Elemento O,Butler JM,Scandura JM,Rafii S
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Jul 17 00:00:00 UTC 2014
Transmigrating neutrophils shape the mucosal microenvironment through localized oxygen depletion to influence resolution of inflammation.
Immunity
Campbell EL,Bruyninckx WJ,Kelly CJ,Glover LE,McNamee EN,Bowers BE,Bayless AJ,Scully M,Saeedi BJ,Golden-Mason L,Ehrentraut SF,Curtis VF,Burgess A,Garvey JF,Sorensen A,Nemenoff R,Jedlicka P,Taylor CT,Kominsky DJ,Colgan SP
14-0451 was used in Flow cytometry/Cell sorting to investigate whether transmigrating neutrophils influence the transcriptional profile of the surrounding mucosa.
Thu Jan 16 00:00:00 UTC 2014
CD4+ T cells promote the transition from hypertrophy to heart failure during chronic pressure overload.
Circulation
Laroumanie F,Douin-Echinard V,Pozzo J,Lairez O,Tortosa F,Vinel C,Delage C,Calise D,Dutaur M,Parini A,Pizzinat N
14-0451 was used in Immunohistochemistry-immunofluorescence to investigate the involvement of T cells in the progression to heart failure using a transverse aortic constriction (TAC) model.
Tue May 27 00:00:00 UTC 2014
Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells.
Nature immunology
Mahmud SA,Manlove LS,Schmitz HM,Xing Y,Wang Y,Owen DL,Schenkel JM,Boomer JS,Green JM,Yagita H,Chi H,Hogquist KA,Farrar MA
14-0451 was used in Flow cytometry/Cell sorting to study the role of TNF receptors in the thymic development of Treg cells..
Thu May 01 00:00:00 UTC 2014
Developmental heterogeneity of cardiac fibroblasts does not predict pathological proliferation and activation.
Circulation research
Ali SR,Ranjbarvaziri S,Talkhabi M,Zhao P,Subat A,Hojjat A,Kamran P,Müller AM,Volz KS,Tang Z,Red-Horse K,Ardehali R
14-0451 was used in Flow cytometry/Cell sorting to study the developmental origins of cardiac fibroblasts and characterise their corresponding phenotypes, to aid in determining the proliferation rates of each developmental subset.
Fri Sep 12 00:00:00 UTC 2014
Developmental heterogeneity of cardiac fibroblasts does not predict pathological proliferation and activation.
Circulation research
Ali SR,Ranjbarvaziri S,Talkhabi M,Zhao P,Subat A,Hojjat A,Kamran P,Müller AM,Volz KS,Tang Z,Red-Horse K,Ardehali R
14-0451 was used in Flow cytometry/Cell sorting to study the developmental origins of cardiac fibroblasts and characterise their corresponding phenotypes, to aid in determining the proliferation rates of each developmental subset.
Fri Sep 12 00:00:00 UTC 2014
Resident fibroblast lineages mediate pressure overload-induced cardiac fibrosis.
The Journal of clinical investigation
Moore-Morris T,Guimarães-Camboa N,Banerjee I,Zambon AC,Kisseleva T,Velayoudon A,Stallcup WB,Gu Y,Dalton ND,Cedenilla M,Gomez-Amaro R,Zhou B,Brenner DA,Peterson KL,Chen J,Evans SM
14-0451 was used in Immunofluorescence to study the the origins of cardiac fibroblasts during development and in fibrosis.
Tue Jul 01 00:00:00 UTC 2014
Sex steroid blockade enhances thymopoiesis by modulating Notch signaling.
The Journal of experimental medicine
Velardi E,Tsai JJ,Holland AM,Wertheimer T,Yu VW,Zakrzewski JL,Tuckett AZ,Singer NV,West ML,Smith OM,Young LF,Kreines FM,Levy ER,Boyd RL,Scadden DT,Dudakov JA,van den Brink MR
14-0451 was used in Flow cytometry/Cell sorting to reveal a novel mechanism underlying improved thymic regeneration upon sex steroid ablation.
Mon Nov 17 00:00:00 UTC 2014
Inhibition of the immunoproteasome ameliorates experimental autoimmune encephalomyelitis.
EMBO molecular medicine
Basler M,Mundt S,Muchamuel T,Moll C,Jiang J,Groettrup M,Kirk CJ
14-0451 was used in Flow cytometry/Cell sorting to investigate the therapeutic efficacy of an immunoproteasome inhibitor, ONX 0914, in two different mouse models of multiple sclerosis.
Sat Feb 01 00:00:00 UTC 2014
Macrophages and β-cells are responsible for CXCR2-mediated neutrophil infiltration of the pancreas during autoimmune diabetes.
EMBO molecular medicine
Diana J,Lehuen A
14-0451 was used in Flow cytometry/Cell sorting to determine the cellular and molecular mechanisms leading to the recruitment of neutrophils in the pancreatic islets of non-obese diabetic mice.
Fri Aug 01 00:00:00 UTC 2014
Increased KIT inhibition enhances therapeutic efficacy in gastrointestinal stromal tumor.
Clinical cancer research : an official journal of the American Association for Cancer Research
Kim TS,Cavnar MJ,Cohen NA,Sorenson EC,Greer JB,Seifert AM,Crawley MH,Green BL,Popow R,Pillarsetty N,Veach DR,Ku AT,Rossi F,Besmer P,Antonescu CR,Zeng S,Dematteo RP
14-0451 was used in Flow cytometry/Cell sorting to explore the ability of PLX3397 to deplete tumour-associated macrophages in gastrointestinal stromal cancer models.
Thu May 01 00:00:00 UTC 2014
p53Ψ is a transcriptionally inactive p53 isoform able to reprogram cells toward a metastatic-like state.
Proceedings of the National Academy of Sciences of the United States of America
Senturk S,Yao Z,Camiolo M,Stiles B,Rathod T,Walsh AM,Nemajerova A,Lazzara MJ,Altorki NK,Krainer A,Moll UM,Lowe SW,Cartegni L,Sordella R
14-0451 was used in Flow cytometry/Cell sorting to describe a unique mode of p53 regulation involving alternative splicing of the TP53 gene.
Tue Aug 12 00:00:00 UTC 2014
p53Ψ is a transcriptionally inactive p53 isoform able to reprogram cells toward a metastatic-like state.
Proceedings of the National Academy of Sciences of the United States of America
Senturk S,Yao Z,Camiolo M,Stiles B,Rathod T,Walsh AM,Nemajerova A,Lazzara MJ,Altorki NK,Krainer A,Moll UM,Lowe SW,Cartegni L,Sordella R
14-0451 was used in Flow cytometry/Cell sorting to describe a unique mode of p53 regulation involving alternative splicing of the TP53 gene.
Tue Aug 12 00:00:00 UTC 2014
Cell-autonomous heparanase modulates self-renewal and migration in bone marrow-derived mesenchymal stem cells.
Journal of biomedical science
Cheng CC,Lee YH,Lin SP,Huangfu WC,Liu IH
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Mar 13 00:00:00 UTC 2014
Astrocytic transforming growth factor-beta signaling reduces subacute neuroinflammation after stroke in mice.
Glia
Cekanaviciute E,Fathali N,Doyle KP,Williams AM,Han J,Buckwalter MS
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Aug 01 00:00:00 UTC 2014
Dual oxidase 2 in lung epithelia is essential for hyperoxia-induced acute lung injury in mice.
Antioxidants & redox signaling
Kim MJ,Ryu JC,Kwon Y,Lee S,Bae YS,Yoon JH,Ryu JH
14-0451 was used in Functional assays to investigate the molecular mechanisms of ROS production in type II alveolar epithelial cells, showing that dual oxidase 2 is essential for hyperoxia-induced acute lung injury.
Sat Nov 01 00:00:00 UTC 2014
Paradoxical resistance to high-fat diet-induced obesity and altered macrophage polarization in mineralocorticoid receptor-overexpressing mice.
American journal of physiology. Endocrinology and metabolism
Kuhn E,Bourgeois C,Keo V,Viengchareun S,Muscat A,Meduri G,Le Menuet D,Fève B,Lombès M
14-0451 was used in Flow cytometry/Cell sorting to investigate the in vivo metabolic impact of the mineralocorticoid receptor (MR), showing that overexpression of MR leads to resistance to high-fat diet-induced obesity and altered macrophage polarisation.
Wed Jan 01 00:00:00 UTC 2014
Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing.
Stem cells (Dayton, Ohio)
Suga H,Rennert RC,Rodrigues M,Sorkin M,Glotzbach JP,Januszyk M,Fujiwara T,Longaker MT,Gurtner GC
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Thu May 01 00:00:00 UTC 2014
Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing.
Stem cells (Dayton, Ohio)
Suga H,Rennert RC,Rodrigues M,Sorkin M,Glotzbach JP,Januszyk M,Fujiwara T,Longaker MT,Gurtner GC
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Thu May 01 00:00:00 UTC 2014
Bone marrow mesenchymal stem cells provide an antibiotic-protective niche for persistent viable Mycobacterium tuberculosis that survive antibiotic treatment.
The American journal of pathology
Beamer G,Major S,Das B,Campos-Neto A
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Dec 01 00:00:00 UTC 2014
Cytokine-regulated neutrophil recruitment is required for brain but not spinal cord inflammation during experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950)
Simmons SB,Liggitt D,Goverman JM
14-0451 was used in Flow cytometry/Cell sorting to investigate the pathways that determine whether damage occurs in the brain or spinal cord in multiple sclerosis, showing that cytokine-regulated neutrophil recruitment is required for brain but not spinal cord.
Tue Jul 15 00:00:00 UTC 2014
Regulatory T cells dynamically regulate selectin ligand function during multiple challenge contact hypersensitivity.
Journal of immunology (Baltimore, Md. : 1950)
Abeynaike LD,Deane JA,Westhorpe CL,Chow Z,Alikhan MA,Kitching AR,Issekutz A,Hickey MJ
14-0451 was used in Immunohistochemistry on frozen tissues to study the rolling of endogenous regulatory T cells in dermal postcapillary venules.
Sat Nov 15 00:00:00 UTC 2014
IL-21 receptor signalling partially mediates Th2-mediated allergic airway responses.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
Lajoie S,Lewkowich I,Herman NS,Sproles A,Pesce JT,Wynn TA,Grusby MJ,Hamid Q,Wills-Karp M
14-0451 was used in Flow cytometry/Cell sorting to suggest that IL-21 plays an important role in the allergic diathesis by enhancing Th2 cytokine production through multiple mechanisms.
Tue Jul 01 00:00:00 UTC 2014
Negative selection by apoptosis enriches progenitors in naïve and expanded human umbilical cord blood grafts.
Bone marrow transplantation
Mizrahi K,Ash S,Peled T,Yaniv I,Stein J,Askenasy N
14-0451-82 was used in Flow cytometry/Cell sorting to evaluate the influence of TNF-α and Fas-ligand on viability and function of umbilical cord blood cells.
Tue Jul 01 00:00:00 UTC 2014
Apoptotic signaling through Fas and TNF receptors ameliorates GVHD in mobilized peripheral blood grafts.
Bone marrow transplantation
Mizrahi K,Yaniv I,Ash S,Stein J,Askenasy N
14-0451 was used in Flow cytometry/Cell sorting to assess the susceptibility of mobilised peripheral blood cells to spontaneous and receptor-induced apoptosis as a possible approach to GVHD prophylaxis.
Thu May 01 00:00:00 UTC 2014
Fgf2 improves functional recovery-decreasing gliosis and increasing radial glia and neural progenitor cells after spinal cord injury.
Brain and behavior
Goldshmit Y,Frisca F,Pinto AR,Pébay A,Tang JK,Siegel AL,Kaslin J,Currie PD
14-0451 was used in Flow cytometry/Cell sorting to demonstrate that early pharmacological intervention with Fgf2 following spinal cord injury is neuroprotective.
Sat Mar 01 00:00:00 UTC 2014
Identification of hematopoietic-specific regulatory elements from the CD45 gene and use for lentiviral tracking of transplanted cells.
Experimental hematology
Duong KL,Das S,Yu S,Barr JY,Jena S,Kim E,Zavazava N,Colgan JD,Xue HH,Levasseur DN
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Sep 01 00:00:00 UTC 2014
KN-93, an inhibitor of calcium/calmodulin-dependent protein kinase IV, promotes generation and function of Foxp3⁺ regulatory T cells in MRL/lpr mice.
Autoimmunity
Koga T,Mizui M,Yoshida N,Otomo K,Lieberman LA,Crispín JC,Tsokos GC
14-0451 was used in Flow cytometry/Cell sorting to investigate the mechanism of CaMK4 on Treg cells in systemic lupus erythematosus, showing that inhibition promotes generation and function of Foxp3+ Tregs.
Sat Nov 01 00:00:00 UTC 2014
No beneficial effect of general and specific anti-inflammatory therapies on aortic dilatation in Marfan mice.
PloS one
Franken R,Hibender S,den Hartog AW,Radonic T,de Vries CJ,Zwinderman AH,Groenink M,Mulder BJ,de Waard V
14-0451 was used in Immunohistochemistry to examine the efficacy of anti-inflammatory therapies in attenuating aortic root dilation in Marfan syndrome and compared effects to the main preventative agent, losartan.
Tue Jun 16 00:00:00 UTC 2015
A new animal model of spontaneous autoimmune peripheral polyneuropathy: implications for Guillain-Barré syndrome.
Acta neuropathologica communications
Yang M,Rainone A,Shi XQ,Fournier S,Zhang J
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Wed Jan 08 00:00:00 UTC 2014
Amniotic fluid stem cells prevent follicle atresia and rescue fertility of mice with premature ovarian failure induced by chemotherapy.
PloS one
Xiao GY,Liu IH,Cheng CC,Chang CC,Lee YH,Cheng WT,Wu SC
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu May 28 00:00:00 UTC 2015
Activation of NLRP3 inflammasome by crystalline structures via cell surface contact.
Scientific reports
Hari A,Zhang Y,Tu Z,Detampel P,Stenner M,Ganguly A,Shi Y
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Dec 02 00:00:00 UTC 2014
The indoleamine 2,3-dioxygenase pathway controls complement-dependent enhancement of chemo-radiation therapy against murine glioblastoma.
Journal for immunotherapy of cancer
Li M,Bolduc AR,Hoda MN,Gamble DN,Dolisca SB,Bolduc AK,Hoang K,Ashley C,McCall D,Rojiani AM,Maria BL,Rixe O,MacDonald TJ,Heeger PS,Mellor AL,Munn DH,Johnson TS
14-0451 was used in Immunohistochemistry to investigate whether Indoleamine 2,3-dioxygenase protects glioblastoma from the full effects of chemo-radiation therapy by preventing vascular activation and complement-dependent tumour destruction.
Wed Jul 23 00:00:00 UTC 2014
The nucleotide-binding leucine-rich repeat (NLR) family member NLRX1 mediates protection against experimental autoimmune encephalomyelitis and represses macrophage/microglia-induced inflammation.
The Journal of biological chemistry
Eitas TK,Chou WC,Wen H,Gris D,Robbins GR,Brickey J,Oyama Y,Ting JP
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Feb 14 00:00:00 UTC 2014
CD28 expression is required after T cell priming for helper T cell responses and protective immunity to infection.
eLife
Linterman MA,Denton AE,Divekar DP,Zvetkova I,Kane L,Ferreira C,Veldhoen M,Clare S,Dougan G,Espéli M,Smith KG
14-0451 was used in Flow cytometry/Cell sorting to determine the role for CD28 after T cell priming.
Mon Oct 27 00:00:00 UTC 2014
Intravenous immunoglobulin (IVIg) provides protection against endothelial cell dysfunction and death in ischemic stroke.
Experimental & translational stroke medicine
Widiapradja A,Santro T,Basta M,Sobey CG,Manzanero S,Arumugam TV
14-0451 was used in Flow cytometry/Cell sorting to study how intravenous immunoglobulin protects endothelial cells from ischaemic insult, supporting its use as a pharmacological intervention for stroke therapy.
Thu Jul 03 00:00:00 UTC 2014
Innate signaling promotes formation of regulatory nitric oxide-producing dendritic cells limiting T-cell expansion in experimental autoimmune myocarditis.
Circulation
Kania G,Siegert S,Behnke S,Prados-Rosales R,Casadevall A,Lüscher TF,Luther SA,Kopf M,Eriksson U,Blyszczuk P
14-0451 was used in Flow cytometry/Cell sorting to investigate how activation of innate pattern-recognition receptors is critical not only for disease induction but also for counterregulatory mechanisms, protecting the heart from exaggerated autoimmunity.
Tue Jun 11 00:00:00 UTC 2013
Anatomically restricted synergistic antiviral activities of innate and adaptive immune cells in the skin.
Cell host & microbe
Hickman HD,Reynoso GV,Ngudiankama BF,Rubin EJ,Magadán JG,Cush SS,Gibbs J,Molon B,Bronte V,Bennink JR,Yewdell JW
14-0451 was used in Flow cytometry/Cell sorting to explore the spatiotemporal organization between antiviral immune cells and vaccinia virus-infected murine cells.
Wed Feb 13 00:00:00 UTC 2013
Mast cell maturation is driven via a group III phospholipase A2-prostaglandin D2-DP1 receptor paracrine axis.
Nature immunology
Taketomi Y,Ueno N,Kojima T,Sato H,Murase R,Yamamoto K,Tanaka S,Sakanaka M,Nakamura M,Nishito Y,Kawana M,Kambe N,Ikeda K,Taguchi R,Nakamizo S,Kabashima K,Gelb MH,Arita M,Yokomizo T,Nakamura M,Watanabe K,Hirai H,Nakamura M,Okayama Y,Ra C,Aritake K,Urade Y,Morimoto K,Sugimoto Y,Shimizu T,Narumiya S,Hara S,Murakami M
14-0451 was used in Flow cytometry/Cell sorting to report that PLA2G3, a mammalian homolog of anaphylactic bee venom phospholipase A2, regulates mast cell maturation via a lipid mediator circuit.
Sat Jun 01 00:00:00 UTC 2013
Nrf2 regulates haematopoietic stem cell function.
Nature cell biology
Tsai JJ,Dudakov JA,Takahashi K,Shieh JH,Velardi E,Holland AM,Singer NV,West ML,Smith OM,Young LF,Shono Y,Ghosh A,Hanash AM,Tran HT,Moore MA,van den Brink MR
14-0451 was used in Flow cytometry/Cell sorting to investigate the link between Nrf2 and CXCR4, thought to partially contribute to the maintenance of haematopoietic stem cell function.
Fri Mar 01 00:00:00 UTC 2013
Inflammatory neovascularization during graft-versus-host disease is regulated by αv integrin and miR-100.
Blood
Leonhardt F,Grundmann S,Behe M,Bluhm F,Dumont RA,Braun F,Fani M,Riesner K,Prinz G,Hechinger AK,Gerlach UV,Dierbach H,Penack O,Schmitt-Gräff A,Finke J,Weber WA,Zeiser R
14-0451-82 was used in Flow Cytometry to identify negative regulation of GvHD-related neovascularization by miR-100.
Thu Apr 25 00:00:00 UTC 2013
A novel mouse model of atherosclerotic plaque instability for drug testing and mechanistic/therapeutic discoveries using gene and microRNA expression profiling.
Circulation research
Chen YC,Bui AV,Diesch J,Manasseh R,Hausding C,Rivera J,Haviv I,Agrotis A,Htun NM,Jowett J,Hagemeyer CE,Hannan RD,Bobik A,Peter K
14-0451 was used in Immunohistochemistry to develop and test therapeutic strategies aimed at preventing plaque rupture.
Fri Jul 19 00:00:00 UTC 2013
Blockade of NOX2 and STIM1 signaling limits lipopolysaccharide-induced vascular inflammation.
The Journal of clinical investigation
Gandhirajan RK,Meng S,Chandramoorthy HC,Mallilankaraman K,Mancarella S,Gao H,Razmpour R,Yang XF,Houser SR,Chen J,Koch WJ,Wang H,Soboloff J,Gill DL,Madesh M
14-0451 was used in Flow cytometry/Cell sorting to elucidate the molecular mechanisms behind the development of LPS-induced acute lung injury.
Fri Feb 01 00:00:00 UTC 2013
Mesenchymal stem cells attenuate ischemic acute kidney injury by inducing regulatory T cells through splenocyte interactions.
Kidney international
Hu J,Zhang L,Wang N,Ding R,Cui S,Zhu F,Xie Y,Sun X,Wu D,Hong Q,Li Q,Shi S,Liu X,Chen X
14-0451 was used in Flow cytometry/Cell sorting to study how mesenchymal stem cells ameliorate ischemic acute kidney injury by inducing regulatory T cells through interactions with splenocytes.
Sun Sep 01 00:00:00 UTC 2013
HDL and Glut1 inhibition reverse a hypermetabolic state in mouse models of myeloproliferative disorders.
The Journal of experimental medicine
Gautier EL,Westerterp M,Bhagwat N,Cremers S,Shih A,Abdel-Wahab O,Lütjohann D,Randolph GJ,Levine RL,Tall AR,Yvan-Charvet L
14-0451 was used in Flow cytometry/Cell sorting to investigate the underlying mechanisms leading to high metabolic rate in myeloproliferative disorders, showing that HDL and Glut1 inhibition reverse hypermetabolic state.
Mon Feb 11 00:00:00 UTC 2013
Avirulent Toxoplasma gondii generates therapeutic antitumor immunity by reversing immunosuppression in the ovarian cancer microenvironment.
Cancer research
Baird JR,Fox BA,Sanders KL,Lizotte PH,Cubillos-Ruiz JR,Scarlett UK,Rutkowski MR,Conejo-Garcia JR,Fiering S,Bzik DJ
14-0451 was used in Flow cytometry/Cell sorting to establish that cps preferentially invades tumour-associated antigen-presenting cells and restores their ability to trigger potent anti-tumour CD8(+) T-cell responses.
Mon Jul 01 00:00:00 UTC 2013
Motile invaded neutrophils in the small intestine of Toxoplasma gondii-infected mice reveal a potential mechanism for parasite spread.
Proceedings of the National Academy of Sciences of the United States of America
Coombes JL,Charsar BA,Han SJ,Halkias J,Chan SW,Koshy AA,Striepen B,Robey EA
14-0451 was used in Flow cytometry/Cell sorting to explore the parasite-host interaction between Toxoplasma gondii and intestinal immune cells.
Tue May 21 00:00:00 UTC 2013
Colonic patch and colonic SILT development are independent and differentially regulated events.
Mucosal immunology
Baptista AP,Olivier BJ,Goverse G,Greuter M,Knippenberg M,Kusser K,Domingues RG,Veiga-Fernandes H,Luster AD,Lugering A,Randall TD,Cupedo T,Mebius RE
14-0451 was used in Immunofluorescence to distinguish the different mechanisms responsible for the formation of two distinct colonic lymphoid tissues.
Wed May 01 00:00:00 UTC 2013
Unique features of naive CD8+ T cell activation by IL-2.
Journal of immunology (Baltimore, Md. : 1950)
Cho JH,Kim HO,Kim KS,Yang DH,Surh CD,Sprent J
14-0451 was used in in vitro experiments to demonstrate that IL-2 elicits a unique signaling pattern associated with strong lymphocyte-specific protein tyrosine kinase/JAK3-dependent activation of the PI3K/AKT pathway.
Sun Dec 01 00:00:00 UTC 2013
Interferon gamma causes olfactory dysfunction without concomitant neuroepithelial damage.
International forum of allergy & rhinology
Pozharskaya T,Lane AP
14-0451 was used in Immunohistochemistry to investigate the direct effect of IFN-γ on olfactory neuron function that may underlie olfactory loss in CRSsNP or viral infections.
Fri Nov 01 00:00:00 UTC 2013
The influence of T cell Ig mucin-3 signaling on central nervous system autoimmune disease is determined by the effector function of the pathogenic T cells.
Journal of immunology (Baltimore, Md. : 1950)
Lee SY,Goverman JM
14-0451 was used in Flow cytometry/Cell sorting to analyse the role of Tim-3 signalling within various innate immune cells on the development of experimental autoimmune encephalomyelitis.
Wed May 15 00:00:00 UTC 2013
Aurintricarboxylic acid ameliorates experimental autoimmune encephalomyelitis by blocking chemokine-mediated pathogenic cell migration and infiltration.
Journal of immunology (Baltimore, Md. : 1950)
Zhang F,Wei W,Chai H,Xie X
14-0451 was used in Immunofluorescence on frozen tissues to investigate the effect of aurintricarboxylic acid (ATA) on experimental autoimmune encephalomyelitis (EAE), showing that ATA ameliorates EAE by blocking chemokine-mediated pathogenic cell migration and infiltration.
Fri Feb 01 00:00:00 UTC 2013
Examining T cells at vaccine sites of tumor-bearing hosts provides insights to dysfunctional T-cell immunity.
Journal of immunotherapy (Hagerstown, Md. : 1997)
Barr KM,Jing W,Hallett WH,Gershan JA,Johnson BD
14-0451 was used in Flow cytometry/Cell sorting to examine immune effectors at vaccine sites to identify mechanisms responsible for the generation of ineffective antitumor immunity, providing insights to dysfunctional T-cell immunity.
Tue Jan 01 00:00:00 UTC 2013
Stromal cells participate in the murine esophageal mucosal injury response.
American journal of physiology. Gastrointestinal and liver physiology
Shaker A,Binkley J,Darwech I,Swietlicki E,McDonald K,Newberry R,Rubin DC
14-0451 was used in Flow cytometry/Cell sorting to study the involvement of esophageal mesenchymal cells expressing α-smooth muscle actin (α-SMA) and vimentin during esophageal injury and repair.
Mon Apr 01 00:00:00 UTC 2013
Reactive oxygen species and IRF1 stimulate IFNα production by proximal tubules during ischemic AKI.
American journal of physiology. Renal physiology
Winterberg PD,Wang Y,Lin KM,Hartono JR,Nagami GT,Zhou XJ,Shelton JM,Richardson JA,Lu CY
14-0451-82 was used in Magnetic cell separation to show that interferon regulatory factor 1 mediates reactive oxygen species signalling, generated during ischemic acute kidney injury and induces interferon-α production.
Mon Jul 15 00:00:00 UTC 2013
CD38 controls the innate immune response against Listeria monocytogenes.
Infection and immunity
Lischke T,Heesch K,Schumacher V,Schneider M,Haag F,Koch-Nolte F,Mittrücker HW
14-0451 was used in Flow cytometry/Cell sorting to evaluate the key enzymes governing the innate immune response.
Fri Nov 01 00:00:00 UTC 2013
Canonical Wnt signaling promotes early hematopoietic progenitor formation and erythroid specification during embryonic stem cell differentiation.
PloS one
Tarafdar A,Dobbin E,Corrigan P,Freeburn R,Wheadon H
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunofluorescence
Tue Jul 29 00:00:00 UTC 2014
Endothelial Jagged-1 is necessary for homeostatic and regenerative hematopoiesis.
Cell reports
Poulos MG,Guo P,Kofler NM,Pinho S,Gutkin MC,Tikhonova A,Aifantis I,Frenette PS,Kitajewski J,Rafii S,Butler JM
14-0451 was used in Flow cytometry/Cell sorting to demonstrate that Jagged-1 expressed in the bone marrow vascular niche regulates homeostatic and regenerative haematopoiesis through a Notch-dependent mechanism.
Thu Sep 12 00:00:00 UTC 2013
Activation and crosstalk between TNF family receptors in umbilical cord blood cells is not responsible for loss of engraftment capacity following culture.
American journal of stem cells
Mizrahi K,Askenasy N
14-0451 was used in Flow cytometry/Cell sorting to assess crosstalk between the Fas, TNF and TRAIL receptors, to determine whether it contributes to increased mortality and decreased activity of UCB progenitors.
Tue Jan 07 00:00:00 UTC 2014
In vivo expansion of co-transplanted T cells impacts on tumor re-initiating activity of human acute myeloid leukemia in NSG mice.
PloS one
von Bonin M,Wermke M,Cosgun KN,Thiede C,Bornhauser M,Wagemaker G,Waskow C
14-0451 was used in Flow cytometry/Cell sorting to investigate the mechanisms behind the limitations of xenotransplantation assays of cells from leukaemia patients into immune compromised mice.
Tue Oct 22 00:00:00 UTC 2013
Gli1 deletion prevents Helicobacter-induced gastric metaplasia and expansion of myeloid cell subsets.
PloS one
El-Zaatari M,Kao JY,Tessier A,Bai L,Hayes MM,Fontaine C,Eaton KA,Merchant JL
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Sep 10 00:00:00 UTC 2013
Exercise reduces activation of microglia isolated from hippocampus and brain of aged mice.
Journal of neuroinflammation
Kohman RA,Bhattacharya TK,Wojcik E,Rhodes JS
14-0451-82 was used in Flow cytometry/Cell sorting to indicate that running-wheel access modulates microglia activation, but these effects vary by age, sex, and brain region.
Wed Sep 18 00:00:00 UTC 2013
The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis.
Nature medicine
Schmidt EP,Yang Y,Janssen WJ,Gandjeva A,Perez MJ,Barthel L,Zemans RL,Bowman JC,Koyanagi DE,Yunt ZX,Smith LP,Cheng SS,Overdier KH,Thompson KR,Geraci MW,Douglas IS,Pearse DB,Tuder RM
14-0451 was used in Flow cytometry/Cell sorting to elucidate the mechanisms by which glycocalyx loss occurs during sepsis, and how this allows for neutrophil adhesion within the pulmonary circulation.
Wed Aug 01 00:00:00 UTC 2012
Rank signaling links the development of invariant γδ T cell progenitors and Aire(+) medullary epithelium.
Immunity
Roberts NA,White AJ,Jenkinson WE,Turchinovich G,Nakamura K,Withers DR,McConnell FM,Desanti GE,Benezech C,Parnell SM,Cunningham AF,Paolino M,Penninger JM,Simon AK,Nitta T,Ohigashi I,Takahama Y,Caamano JH,Hayday AC,Lane PJ,Jenkinson EJ,Anderson G
14-0451 was used in Flow cytometry/Cell sorting to study the temporal development of Vγ5(+) γδ T cells during thymus medulla formation.
Fri Mar 23 00:00:00 UTC 2012
Prostaglandin E2 suppresses antifungal immunity by inhibiting interferon regulatory factor 4 function and interleukin-17 expression in T cells.
Immunity
Valdez PA,Vithayathil PJ,Janelsins BM,Shaffer AL,Williamson PR,Datta SK
14-0451 was used in Flow cytometry/Cell sorting to study the effect of prostaglandin E2 on the function of Th17 cells during differentiation.
Fri Apr 20 00:00:00 UTC 2012
Tumorigenic cells are common in mouse MPNSTs but their frequency depends upon tumor genotype and assay conditions.
Cancer cell
Buchstaller J,McKeever PE,Morrison SJ
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Feb 14 00:00:00 UTC 2012
Autophagy links inflammasomes to atherosclerotic progression.
Cell metabolism
Razani B,Feng C,Coleman T,Emanuel R,Wen H,Hwang S,Ting JP,Virgin HW,Kastan MB,Semenkovich CF
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunofluorescence
Wed Apr 04 00:00:00 UTC 2012
IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia.
Nature immunology
Wang Y,Szretter KJ,Vermi W,Gilfillan S,Rossini C,Cella M,Barrow AD,Diamond MS,Colonna M
14-0451 was used in Flow cytometry/Cell sorting to investigate whether IL-34 is responsible for the lack of Langerhans cells and microglia in CSF1R-deficient mice.
Sun Jun 24 00:00:00 UTC 2012
Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells.
Blood
Tewalt EF,Cohen JN,Rouhani SJ,Guidi CJ,Qiao H,Fahl SP,Conaway MR,Bender TP,Tung KS,Vella AT,Adler AJ,Chen L,Engelhard VH
14-0451 was used in Flow cytometry/Cell sorting to demonstrate that LECs mediate deletion only via programmed cell death-1 (PD-1) ligand 1.
Thu Dec 06 00:00:00 UTC 2012
Lung B cells promote early pathogen dissemination and hasten death from inhalation anthrax.
Mucosal immunology
Rayamajhi M,Delgado C,Condon TV,Riches DW,Lenz LL
14-0451 was used in Flow cytometry/Cell sorting to investigate mechanisms of Bacillus anthracis spore traffic from the lungs to the lung-draining lymph nodes in a mouse model of inhalation anthrax.
Sun Jul 01 00:00:00 UTC 2012
Etv2 is expressed in the yolk sac hematopoietic and endothelial progenitors and regulates Lmo2 gene expression.
Stem cells (Dayton, Ohio)
Koyano-Nakagawa N,Kweon J,Iacovino M,Shi X,Rasmussen TL,Borges L,Zirbes KM,Li T,Perlingeiro RC,Kyba M,Garry DJ
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Wed Aug 01 00:00:00 UTC 2012
Transgenic expression of interferon-γ in mouse stomach leads to inflammation, metaplasia, and dysplasia.
The American journal of pathology
Syu LJ,El-Zaatari M,Eaton KA,Liu Z,Tetarbe M,Keeley TM,Pero J,Ferris J,Wilbert D,Kaatz A,Zheng X,Qiao X,Grachtchouk M,Gumucio DL,Merchant JL,Samuelson LC,Dlugosz AA
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Sat Dec 01 00:00:00 UTC 2012
Epithelial expression of the cytosolic retinoid chaperone cellular retinol binding protein II is essential for in vivo imprinting of local gut dendritic cells by lumenal retinoids.
The American journal of pathology
McDonald KG,Leach MR,Brooke KWM,Wang C,Wheeler LW,Hanly EK,Rowley CW,Levin MS,Wagner M,Li E,Newberry RD
14-0451 was used in Flow cytometry/Cell sorting to study dendritic cell production of all-trans retinoic acid (ATRA) in vivo.
Thu Mar 01 00:00:00 UTC 2012
Intratumoral hu14.18-IL-2 (IC) induces local and systemic antitumor effects that involve both activated T and NK cells as well as enhanced IC retention.
Journal of immunology (Baltimore, Md. : 1950)
Yang RK,Kalogriopoulos NA,Rakhmilevich AL,Ranheim EA,Seo S,Kim K,Alderson KL,Gan J,Reisfeld RA,Gillies SD,Hank JA,Sondel PM
14-0451 was used in Immunohistochemistry to study how IT-IC resulted in increased numbers of activated T and NK cells within tumours, better IC retention in the tumour, enhanced inhibition of tumour growth, and improved survival compared with i.v.-IC.
Sat Sep 01 00:00:00 UTC 2012
A model of GAG/MIP-2/CXCR2 interfaces and its functional effects.
Biochemistry
Rajasekaran D,Keeler C,Syed MA,Jones MC,Harrison JK,Wu D,Bhandari V,Hodsdon ME,Lolis EJ
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Jul 17 00:00:00 UTC 2012
Tissue specific deletion of inhibitor of kappa B kinase 2 with OX40-Cre reveals the unanticipated expression from the OX40 locus in skin epidermis.
PloS one
Cornish GH,Tung SL,Marshall D,Ley S,Seddon BP
14-0451 was used in Immunofluorescence on frozen tissues to investigate the role of NF-κB signalling in post-activation T cells.
Fri Jun 29 00:00:00 UTC 2012
Delta-like ligand (DLL)1 expression in early mouse decidua and its localization to uterine natural killer cells.
PloS one
Degaki KY,Chen Z,Yamada AT,Croy BA
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunofluorescence
Tue Jun 25 00:00:00 UTC 2013
Cell type-associated differences in migration, survival, and immunogenicity following grafting in CNS tissue.
Cell transplantation
Praet J,Reekmans K,Lin D,De Vocht N,Bergwerf I,Tambuyzer B,Daans J,Hens N,Goossens H,Pauwels P,Berneman Z,Van der Linden A,Ponsaerts P
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Dec 06 00:00:00 UTC 2013
Kuppfer cells trigger nonalcoholic steatohepatitis development in diet-induced mouse model through tumor necrosis factor-α production.
The Journal of biological chemistry
Tosello-Trampont AC,Landes SG,Nguyen V,Novobrantseva TI,Hahn YS
14-0451 was used in Flow cytometry/Cell sorting to define the mechanisms that trigger nonalcoholic steatohepatitis.
Fri Nov 23 00:00:00 UTC 2012
Activation of MDL-1 (CLEC5A) on immature myeloid cells triggers lethal shock in mice.
The Journal of clinical investigation
Cheung R,Shen F,Phillips JH,McGeachy MJ,Cua DJ,Heyworth PG,Pierce RH
14-0451 was used in Flow cytometry/Cell sorting to identify the MDL-1/Syk/PI3K/Akt/eNOS pathway as a potential new target for the prevention of the progression of SIRS to shock.
Tue Nov 01 00:00:00 UTC 2011
Early interleukin 6 production by leukocytes during ischemic acute kidney injury is regulated by TLR4.
Kidney international
Chen J,Hartono JR,John R,Bennett M,Zhou XJ,Wang Y,Wu Q,Winterberg PD,Nagami GT,Lu CY
14-0451 was used in Immunopurification to study the regulation of leukocytes' early interleukin 6 production during ischemic acute kidney injury.
Thu Sep 01 00:00:00 UTC 2011
Coordinate regulation of tissue macrophage and dendritic cell population dynamics by CSF-1.
The Journal of experimental medicine
Tagliani E,Shi C,Nancy P,Tay CS,Pamer EG,Erlebacher A
14-0451 was used in Flow cytometry/Cell sorting to provide insight into the regulation of MΦ tissue densities under noninflammatory conditions and reveal a central role for CSF-1 in the coordination of MΦ and DC homeostasis.
Mon Aug 29 00:00:00 UTC 2011
Induction of potent anti-tumor responses while eliminating systemic side effects via liposome-anchored combinatorial immunotherapy.
Biomaterials
Kwong B,Liu H,Irvine DJ
14-0451 was used in Flow cytometry/Cell sorting to investigate whether systemic exposure to immuno-agonist compounds could be limited to local tumour tissue, showing that liposome-anchored combinatorial immunotherapy could induce potent anti-tumor response.
Mon Aug 01 00:00:00 UTC 2011
A role for leukocyte-derived IL-1RA in DC homeostasis revealed by increased susceptibility of IL-1RA-deficient mice to cutaneous leishmaniasis.
The Journal of investigative dermatology
Kautz-Neu K,Kostka SL,Dinges S,Iwakura Y,Udey MC,von Stebut E
14-0451 was used in an ELISA assay to suggest that in addition to effects on Th education, IL-1α/β signalling also modulates DC homeostasis with increased signalling, leading to down-modulation of IL-12 synthesis and worsened disease outcome after infection with Leishmania major.
Mon Aug 01 00:00:00 UTC 2011
A role for leukocyte-derived IL-1RA in DC homeostasis revealed by increased susceptibility of IL-1RA-deficient mice to cutaneous leishmaniasis.
The Journal of investigative dermatology
Kautz-Neu K,Kostka SL,Dinges S,Iwakura Y,Udey MC,von Stebut E
14-0451 was used in an ELISA assay to suggest that in addition to effects on Th education, IL-1α/β signalling also modulates DC homeostasis with increased signalling, leading to down-modulation of IL-12 synthesis and worsened disease outcome after infection with Leishmania major.
Mon Aug 01 00:00:00 UTC 2011
ER71 directs mesodermal fate decisions during embryogenesis.
Development (Cambridge, England)
Rasmussen TL,Kweon J,Diekmann MA,Belema-Bedada F,Song Q,Bowlin K,Shi X,Ferdous A,Li T,Kyba M,Metzger JM,Koyano-Nakagawa N,Garry DJ
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Nov 01 00:00:00 UTC 2011
The anti-tumor effect of resveratrol alone or in combination with immunotherapy in a neuroblastoma model.
Cancer immunology, immunotherapy : CII
Soto BL,Hank JA,Van De Voort TJ,Subramanian L,Polans AS,Rakhmilevich AL,Yang RK,Seo S,Kim K,Reisfeld RA,Gillies SD,Sondel PM
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunohistochemistry
Sun May 01 00:00:00 UTC 2011
Functional redundancy between thymic CD8α+ and Sirpα+ conventional dendritic cells in presentation of blood-derived lysozyme by MHC class II proteins.
Journal of immunology (Baltimore, Md. : 1950)
Atibalentja DF,Murphy KM,Unanue ER
14-0451 was used in Flow cytometry/Cell sorting to evaluate the presentation of blood-derived protein Ags by antigen presenting cells in the thymus.
Tue Feb 01 00:00:00 UTC 2011
Effect of topical azithromycin on corneal innate immune responses.
Investigative ophthalmology & visual science
Sadrai Z,Hajrasouliha AR,Chauhan S,Saban DR,Dastjerdi MH,Dana R
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Tue Apr 19 00:00:00 UTC 2011
Myeloid cells migrate in response to IL-24.
Cytokine
Buzas K,Oppenheim JJ,Zack Howard OM
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Thu Sep 01 00:00:00 UTC 2011
Localized delivery of interferon-β by Lactobacillus exacerbates experimental colitis.
PloS one
McFarland AP,Savan R,Wagage S,Addison A,Ramakrishnan K,Karwan M,Duong T,Young HA
14-0451 was used in Flow cytometry/Cell sorting to identify a correlation between the loss/down-regulation of IFNAR1 on DCs and exacerbation of colitis.
Fri Feb 18 00:00:00 UTC 2011
Clinical potential of intravenous neural stem cell delivery for treatment of neuroinflammatory disease in mice?
Cell transplantation
Reekmans KP,Praet J,De Vocht N,Tambuyzer BR,Bergwerf I,Daans J,Baekelandt V,Vanhoutte G,Goossens H,Jorens PG,Ysebaert DK,Chatterjee S,Pauwels P,Van Marck E,Berneman ZN,Van der Linden A,Ponsaerts P
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Fri Dec 09 00:00:00 UTC 2011
Progression of cancer from indolent to aggressive despite antigen retention and increased expression of interferon-gamma inducible genes.
Cancer immunity
Wu TH,Schreiber K,Arina A,Khodarev NN,Efimova EV,Rowley DA,Weichselbaum RR,Schreiber H
14-0451 was used in Flow cytometry/Cell sorting to characterize stepwise progression of an antigenic tumor and show that different mechanisms work to prevent tumor cell recognition and elimination.
Thu Jun 30 00:00:00 UTC 2011
Regulation of medullary thymic epithelial cell differentiation and function by the signaling protein Sin.
The Journal of experimental medicine
Danzl NM,Donlin LT,Alexandropoulos K
14-0451 was used in Flow cytometry/Cell sorting to reveal the role of the signalling protein Sin in the thymic stroma, specifically in medullary thymic epithelial cells.
Mon May 10 00:00:00 UTC 2010
CXCR4 signaling regulates metastasis of chemoresistant melanoma cells by a lymphatic metastatic niche.
Cancer research
Kim M,Koh YJ,Kim KE,Koh BI,Nam DH,Alitalo K,Kim I,Koh GY
14-0451 was used in Flow cytometry/Cell sorting to investigate the mechanisms responsible for the aggressive characteristics of malignant melanomas, showing that CXCR4 signaling regulates metastasis.
Wed Dec 15 00:00:00 UTC 2010
The natriuretic peptide/guanylyl cyclase--a system functions as a stress-responsive regulator of angiogenesis in mice.
The Journal of clinical investigation
Kuhn M,Völker K,Schwarz K,Carbajo-Lozoya J,Flögel U,Jacoby C,Stypmann J,van Eickels M,Gambaryan S,Hartmann M,Werner M,Wieland T,Schrader J,Baba HA
14-0451 was used in Immunohistochemistry on paraffin embedded tissues to identify a novel function of cardiac atrial natriuretic peptide and B-type natriuretic peptide as paracrine regulators of vascular regeneration.
Wed Jul 01 00:00:00 UTC 2009
Mice that overexpress human heat shock protein 27 have increased renal injury following ischemia reperfusion.
Kidney international
Chen SW,Kim M,Kim M,Song JH,Park SW,Wells D,Brown K,Belleroche Jd,D'Agati VD,Lee HT
14-0451 was used in Flow cytometry/Cell sorting to investigate increased renal injury in mice that overexpress human heat shock protein 27 following ischemia reperfusion.
Sun Mar 01 00:00:00 UTC 2009
Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development.
Hepatology (Baltimore, Md.)
Asahina K,Tsai SY,Li P,Ishii M,Maxson RE,Sucov HM,Tsukamoto H
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunofluorescence
Sun Mar 01 00:00:00 UTC 2009
The NOD/RIP2 pathway is essential for host defenses against Chlamydophila pneumoniae lung infection.
PLoS pathogens
Shimada K,Chen S,Dempsey PW,Sorrentino R,Alsabeh R,Slepenkin AV,Peterson E,Doherty TM,Underhill D,Crother TR,Arditi M
14-0451 was used in Flow cytometry/Cell sorting to investigate the role of the Nod/Rip2 pathway in responses to Chlamydophila pneumoniae infection, showing that it is essential for host defences against pneumonia.
Wed Apr 01 00:00:00 UTC 2009
Involvement of IQGAP3, a regulator of Ras/ERK-related cascade, in hepatocyte proliferation in mouse liver regeneration and development.
Journal of cellular physiology
Kunimoto K,Nojima H,Yamazaki Y,Yoshikawa T,Okanoue T,Tsukita S
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Immunofluorescence
Tue Sep 01 00:00:00 UTC 2009
Adenosine A2B receptors are highly expressed on murine type II alveolar epithelial cells.
American journal of physiology. Lung cellular and molecular physiology
Cagnina RE,Ramos SI,Marshall MA,Wang G,Frazier CR,Linden J
14-0451 was used in Functional assays to determine the sites of expression of the A(2B) receptor in the mouse lung, showing that they are highly expressed on murine type II alveolar epithelial cells.
Tue Sep 01 00:00:00 UTC 2009
Chemokine-like receptor-1 expression by central nervous system-infiltrating leukocytes and involvement in a model of autoimmune demyelinating disease.
Journal of immunology (Baltimore, Md. : 1950)
Graham KL,Zabel BA,Loghavi S,Zuniga LA,Ho PP,Sobel RA,Butcher EC
14-0451 was used in Flow cytometry/Cell sorting to investigate the involvement of chemokine-like receptor-1 in experimental autoimmune encephalomyelitis.
Sun Nov 15 00:00:00 UTC 2009
Peripheral dendritic cells are essential for both the innate and adaptive antiviral immune responses in the central nervous system.
Virology
Steel CD,Hahto SM,Ciavarra RP
14-0451-82 was used in Flow Cytometry to study the adaptive primary antiviral immune response in the CNS and the effect of dendritic cells upon this in vivo.
Sat Apr 25 00:00:00 UTC 2009
p21Cip1 modulates arterial wound repair through the stromal cell-derived factor-1/CXCR4 axis in mice.
The Journal of clinical investigation
Olive M,Mellad JA,Beltran LE,Ma M,Cimato T,Noguchi AC,San H,Childs R,Kovacic JC,Boehm M
14-0451 was used in Immunofluorescence on frozen tissues to show that p21Cip1 orchestrates the complex interactions between local vascular and circulating immune cells during vascular wound repair.
Sun Jun 01 00:00:00 UTC 2008
Th1 and Th2 cells form morphologically distinct immunological synapses.
Journal of immunology (Baltimore, Md. : 1950)
Thauland TJ,Koguchi Y,Wetzel SA,Dustin ML,Parker DC
14-0451 was used in Immunocytochemistry-immunoflourescence to indicate that the immunological synapse formed by Th1 and Th2 cells are distinct in structure.
Tue Jul 01 00:00:00 UTC 2008
Donor major histocompatibility complex class I expression determines the outcome of prenatal transplantation.
Journal of pediatric surgery
Durkin ET,Jones KA,Elnaggar D,Shaaban AF
14-0451 was used in Flow cytometry/Cell sorting to investigate whether donor cell MHC class I expression facilitates engraftment in prenatal allogeneic recipients, showing that it determines the outcome of prenatal transplantation.
Sun Jun 01 00:00:00 UTC 2008
Increased TSLP availability restores T- and B-cell compartments in adult IL-7 deficient mice.
Blood
Chappaz S,Flueck L,Farr AG,Rolink AG,Finke D
14-0451 was used in Flow cytometry/Cell sorting to investigate the role of TSLP in lymphopoiesis and immune cell development in IL-7-deficient mice.
Sat Dec 01 00:00:00 UTC 2007
Optimized isolation enables ex vivo analysis of microglia from various central nervous system regions.
Glia
de Haas AH,Boddeke HW,Brouwer N,Biber K
Published figure using CD45 monoclonal antibody (Product # 14-0451-82) in Flow Cytometry
Mon Oct 01 00:00:00 UTC 2007
Lateral compartmentalization of T cell receptor versus CD45 by galectin-N-glycan binding and microfilaments coordinate basal and activation signaling.
The Journal of biological chemistry
Chen IJ,Chen HL,Demetriou M
14-0451 was used in Immunofluorescence to investigate the role of the galectin lattice and actin cytoskeleton in controlling microdomain structure and coordinating signal transduction across the plasma membrane.
Fri Nov 30 00:00:00 UTC 2007
Role of T and NK cells and IL7/IL7r interactions during neonatal maturation of lymph nodes.
Proceedings of the National Academy of Sciences of the United States of America
Coles MC,Veiga-Fernandes H,Foster KE,Norton T,Pagakis SN,Seddon B,Kioussis D
14-0451 was used in Flow cytometry/Cell sorting to reveal a potential role for mature lymphocytes and IL7/IL7r interactions in postnatal lymph node development.
Tue Sep 05 00:00:00 UTC 2006
