Product References
Spleen-targeted neoantigen DNA vaccine for personalized immunotherapy of hepatocellular carcinoma.
EMBO molecular medicine
Wu M,Luo Z,Cai Z,Mao Q,Li Z,Li H,Zhang C,Zhang Y,Zhong A,Wu L,Liu X
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed Oct 11 00:00:00 EDT 2023
Fibroblastic reticular cells in lymph node potentiate white adipose tissue beiging through neuro-immune crosstalk in male mice.
Nature communications
Cheong LY,Wang B,Wang Q,Jin L,Kwok KHM,Wu X,Shu L,Lin H,Chung SK,Cheng KKY,Hoo RLC,Xu A
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Mar 03 00:00:00 EST 2023
Calcaratarin D, a labdane diterpenoid, attenuates mouse asthma via modulating alveolar macrophage function.
British journal of pharmacology
Liao W,Foo HYC,Tran TNQ,Chai CLL,Wong WSF
25-0451-82 was used in Flow cytometry/Cell sorting to demonstrate for the first time that CalD is a novel anti-inflammatory natural compound for allergic asthma that modulates AM function.
Sat Apr 01 00:00:00 EDT 2023
Human serum albumin promotes self-renewal and expansion of umbilical cord blood CD34+ hematopoietic stem/progenitor cells.
Annals of translational medicine
Hua J,Jiao T,Qiao Y,Zhang S,Xiao T,Zhang Y,Yan J
25-0451-82 was used in Flow Cytometry to find that HSA was beneficial to maintaining CD34+ cell expansion and short-term colony formation in vitro and optimizing multilineage reconstitution in immunodeficient mice in vivo.
Tue Jan 31 00:00:00 EST 2023
Hypercapnia alters stroma-derived Wnt production to limit β-catenin signaling and proliferation in AT2 cells.
JCI insight
Dada LA,Welch LC,Magnani ND,Ren Z,Han H,Brazee PL,Celli D,Flozak AS,Weng A,Herrerias MM,Kryvenko V,Vadász I,Runyan CE,Abdala-Valencia H,Shigemura M,Casalino-Matsuda SM,Misharin AV,Budinger GRS,Gottardi CJ,Sznajder JI
25-0451-82 was used in Flow cytometry/Cell sorting to show that constitutive activation of β-catenin signaling in AT2 cells or treatment of organoid cultures with recombinant WNT3A protein bypasses the inhibitory effects of hypercapnia. Inhibition of AT2 proliferation in hypercapnic patients may contribute to impaired lung repair after injury, preventing sealing of the epithelial barrier, increasing lung flooding, ventilator dependency and mortality..
Wed Feb 22 00:00:00 EST 2023
Macrophagic AMPKα1 orchestrates regenerative inflammation induced by glucocorticoids.
EMBO reports
Caratti G,Desgeorges T,Juban G,Stifel U,Fessard A,Koenen M,Caratti B,Théret M,Skurk C,Chazaud B,Tuckermann JP,Mounier R
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Feb 06 00:00:00 EST 2023
Macrophagic AMPKα1 orchestrates regenerative inflammation induced by glucocorticoids.
EMBO reports
Caratti G,Desgeorges T,Juban G,Stifel U,Fessard A,Koenen M,Caratti B,Théret M,Skurk C,Chazaud B,Tuckermann JP,Mounier R
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Feb 06 00:00:00 EST 2023
Targeting myocardial equilibrative nucleoside transporter ENT1 provides cardioprotection by enhancing myeloid Adora2b signaling.
JCI insight
Ruan W,Li J,Choi S,Ma X,Liang Y,Nair R,Yuan X,Mills TW,Eltzschig HK
25-0451-82 was used in Flow cytometry/Cell sorting to reveal a previously unrecognized role for myocyte-specific ENT1 in cardioprotection by enhancing myeloid-dependent Adora2b signaling during reperfusion.
Thu Jun 08 00:00:00 EDT 2023
Topical Diacerein Decreases Skin and Splenic CD11c+ Dendritic Cells in Psoriasis.
International journal of molecular sciences
Brunner SM,Ramspacher A,Rieser C,Leitner J,Heil H,Ablinger M,Tevini J,Wimmer M,Koller A,Piñón Hofbauer J,Felder TK,Bauer JW,Kofler B,Lang R,Wally V
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Feb 21 00:00:00 EST 2023
Role of PDGFRA+ cells and a CD55+ PDGFRALo fraction in the gastric mesenchymal niche.
Nature communications
Manieri E,Tie G,Malagola E,Seruggia D,Madha S,Maglieri A,Huang K,Fujiwara Y,Zhang K,Orkin SH,Wang TC,He R,McCarthy N,Shivdasani RA
25-0451-82 was used in Flow Cytometry to shed light on spatial, molecular, and functional organization of gastric mesenchyme and the spectrum of signaling sources for epithelial support.
Sat Dec 02 00:00:00 EST 2023
A newly-synthesized compound CP-07 alleviates microglia-mediated neuroinflammation and ischemic brain injury via inhibiting STAT3 phosphorylation.
Journal of translational internal medicine
Guo M,Cao Q,Xia S,Cao X,Chen J,Qian Y,Bao X,Xu Y
25-0451-82 was used in Flow cytometry/Cell sorting to show that a newly synthesized compound, CP-07, could effectively reduce the inflammatory responses in LPS-stimulated BV2 cells and primary mouse microglia, and overproduction of cytokines in middle cerebral artery occlusion mouse models by inhibiting STAT3 phosphorylation, leading to a neuroprotective effect on I/R brain injury.
Sat Jul 01 00:00:00 EDT 2023
BRCA1 deficiency in mature CD8+ T lymphocytes impairs antitumor immunity.
Journal for immunotherapy of cancer
Wu B,Qi L,Chiang HC,Pan H,Zhang X,Greenbaum A,Stark E,Wang LJ,Chen Y,Haddad BR,Clagett D,Isaacs C,Elledge R,Horvath A,Hu Y,Li R
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2023
CD11c+ microglia promote white matter repair after ischemic stroke.
Cell death & disease
Jia J,Zheng L,Ye L,Chen J,Shu S,Xu S,Bao X,Xia S,Liu R,Xu Y,Zhang M
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Feb 24 00:00:00 EST 2023
Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zhang Y,Liu T,Deng Z,Fang W,Zhang X,Zhang S,Wang M,Luo S,Meng Z,Liu J,Sukhova GK,Li D,McKenzie ANJ,Libby P,Shi GP,Guo J
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2023
Assessing the effects of aging on the renal endothelial cell landscape using single-cell RNA sequencing.
Frontiers in genetics
Li M,Wang D,Liu Z,Huang Y,Zhang Q,Pan C,Lin Y,Sun L,Zheng Y
25-0451-82 was used in Flow cytometry/Cell sorting to create a transcriptome atlas of murine renal ECs and identify transcriptomic changes that occur during aging.
Tue May 23 00:00:00 EDT 2023
Group 2 innate lymphoid cells protect mouse heart from myocardial infarction injury via interleukin 5, eosinophils, and dendritic cells.
Cardiovascular research
Liu T,Meng Z,Liu J,Li J,Zhang Y,Deng Z,Luo S,Wang M,Huang Q,Zhang S,Fendt P,Devouassoux J,Li D,McKenzie ANJ,Nahrendorf M,Libby P,Guo J,Shi GP
25-0451-82 was used in Flow cytometry/Cell sorting to reveal an indirect cardiac reparative role of ILC2 in post-MI hearts via the IL5, EOS, and DC mechanism.
Tue May 02 00:00:00 EDT 2023
Targeting adrenergic receptors to mitigate invariant natural killer T cells-induced acute liver injury.
iScience
Gonzatti MB,Freire BM,Antunes MM,de Menezes GB,Talbot J,Peron JPS,Basso AS,Keller AC
25-0451-82 was used in Flow Cytometry to suggest that the modulation of the adrenergic signaling can be a complementary approach to αGC-based immunotherapy to mitigate iNKT-induced liver injury without compromising its antitumoral activity.
Fri Oct 20 00:00:00 EDT 2023
Senolytic elimination of Cox2-expressing senescent cells inhibits the growth of premalignant pancreatic lesions.
Gut
Kolodkin-Gal D,Roitman L,Ovadya Y,Azazmeh N,Assouline B,Schlesinger Y,Kalifa R,Horwitz S,Khalatnik Y,Hochner-Ger A,Imam A,Demma JA,Winter E,Benyamini H,Elgavish S,Khatib AA,Meir K,Atlan K,Pikarsky E,Parnas O,Dor Y,Zamir G,Ben-Porath I,Krizhanovsky V
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Immunohistochemistry
Tue Feb 01 00:00:00 EST 2022
The ZIP8/SIRT1 axis regulates alveolar progenitor cell renewal in aging and idiopathic pulmonary fibrosis.
The Journal of clinical investigation
Liang J,Huang G,Liu X,Taghavifar F,Liu N,Wang Y,Deng N,Yao C,Xie T,Kulur V,Dai K,Burman A,Rowan SC,Weigt SS,Belperio J,Stripp B,Parks WC,Jiang D,Noble PW
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed Jun 01 00:00:00 EDT 2022
Interleukin-10 genetically modified clinical-grade mesenchymal stromal cells markedly reinforced functional recovery after spinal cord injury via directing alternative activation of macrophages.
Cellular & molecular biology letters
Gao T,Huang F,Wang W,Xie Y,Wang B
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Mar 17 00:00:00 EDT 2022
BEX1 is a critical determinant of viral myocarditis.
PLoS pathogens
Martens CR,Dorn LE,Kenney AD,Bansal SS,Yount JS,Accornero F
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Feb 01 00:00:00 EST 2022
BEX1 is a critical determinant of viral myocarditis.
PLoS pathogens
Martens CR,Dorn LE,Kenney AD,Bansal SS,Yount JS,Accornero F
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Feb 01 00:00:00 EST 2022
GPR92 activation in islet macrophages controls β cell function in a diet-induced obesity model.
The Journal of clinical investigation
de Souza CO,Paschoal VA,Sun X,Vishvanath L,Zhang Q,Shao M,Onodera T,Chen S,Joffin N,Bueno LM,Gupta RK,Oh DY
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2022
Mineralocorticoid receptor antagonists and glucocorticoids differentially affect skeletal muscle inflammation and pathology in muscular dystrophy.
JCI insight
Howard ZM,Gomatam CK,Rabolli CP,Lowe J,Piepho AB,Bansal SS,Accornero F,Rafael-Fortney JA
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Oct 10 00:00:00 EDT 2022
Comparative analysis of thoracic and abdominal aortic aneurysms across the segment and species at the single-cell level.
Frontiers in pharmacology
Wu H,Xie C,Wang R,Cheng J,Xu Q,Zhao H
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Feb 02 00:00:00 EST 2023
Microglial angiotensin type 2 receptors mediate sex-specific expression of inflammatory cytokines independently of circulating estrogen.
Glia
Garrido-Gil P,Pedrosa MA,Garcia-Garrote M,Pequeño-Valtierra A,Rodríguez-Castro J,García-Souto D,Rodríguez-Pérez AI,Labandeira-Garcia JL
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2022
Hematopoietic-Mesenchymal Signals Regulate the Properties of Mesenchymal Stem Cells.
International journal of molecular sciences
Kanazawa S,Okada H,Riu D,Mabuchi Y,Akazawa C,Iwata J,Hoshi K,Hikita A
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Jul 26 00:00:00 EDT 2022
Hematopoietic-Mesenchymal Signals Regulate the Properties of Mesenchymal Stem Cells.
International journal of molecular sciences
Kanazawa S,Okada H,Riu D,Mabuchi Y,Akazawa C,Iwata J,Hoshi K,Hikita A
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Jul 26 00:00:00 EDT 2022
Gene-selective transcription promotes the inhibition of tissue reparative macrophages by TNF.
Life science alliance
Dichtl S,Sanin DE,Koss CK,Willenborg S,Petzold A,Tanzer MC,Dahl A,Kabat AM,Lindenthal L,Zeitler L,Satzinger S,Strasser A,Mann M,Roers A,Eming SA,El Kasmi KC,Pearce EJ,Murray PJ
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Apr 01 00:00:00 EDT 2022
Intranasal delivery of a small-molecule ErbB inhibitor promotes recovery from acute and late-stage CNS inflammation.
JCI insight
Linnerbauer M,Lößlein L,Vandrey O,Tsaktanis T,Beer A,Naumann UJ,Panier F,Beyer T,Nirschl L,Kuramatsu JB,Winkler J,Quintana FJ,Rothhammer V
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Apr 08 00:00:00 EDT 2022
OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage.
Nature
Wu XS,He XY,Ipsaro JJ,Huang YH,Preall JB,Ng D,Shue YT,Sage J,Egeblad M,Joshua-Tor L,Vakoc CR
25-0451-82 was used in Flow cytometry/Cell sorting to reveal that the POU2F3-OCA-T complex is the master regulator of tuft cell identity and a molecular vulnerability of tuft-cell-like small-cell lung cancer.
Fri Jul 01 00:00:00 EDT 2022
Tumor collection/processing under physioxia uncovers highly relevant signaling networks and drug sensitivity.
Science advances
Kumar B,Adebayo AK,Prasad M,Capitano ML,Wang R,Bhat-Nakshatri P,Anjanappa M,Simpson E,Chen D,Liu Y,Schilder JM,Colter AB,Maguire C,Temm CJ,Sandusky G,Doud EH,Wijeratne AB,Mosley AL,Broxmeyer HE,Nakshatri H
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Jan 14 00:00:00 EST 2022
Tumor collection/processing under physioxia uncovers highly relevant signaling networks and drug sensitivity.
Science advances
Kumar B,Adebayo AK,Prasad M,Capitano ML,Wang R,Bhat-Nakshatri P,Anjanappa M,Simpson E,Chen D,Liu Y,Schilder JM,Colter AB,Maguire C,Temm CJ,Sandusky G,Doud EH,Wijeratne AB,Mosley AL,Broxmeyer HE,Nakshatri H
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Jan 14 00:00:00 EST 2022
The RNA-binding protein IMP2 drives a stromal-Th17 cell circuit in autoimmune neuroinflammation.
JCI insight
Bechara R,Amatya N,Majumder S,Zhou C,Li Y,Liu Q,McGeachy MJ,Gaffen SL
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Feb 08 00:00:00 EST 2022
P140 Peptide Leads to Clearance of Autoreactive Lymphocytes and Normalizes Immune Response in Lupus-Prone Mice.
Frontiers in immunology
Schall N,Talamini L,Wilhelm M,Jouvin-Marche E,Muller S
25-0451-82 was used in Flow cytometry/Cell sorting to suggest that P140 belongs to a new family of non-immunosuppressive immunoregulators that do not correct T and B cell abnormalities but rather contribute to the clearance of deleterious T and B cells.
Tue Jun 21 00:00:00 EDT 2022
Myeloid mineralocorticoid receptors contribute to skeletal muscle repair in muscular dystrophy and acute muscle injury.
American journal of physiology. Cell physiology
Howard ZM,Rastogi N,Lowe J,Hauck JS,Ingale P,Gomatam C,Gomez-Sanchez CE,Gomez-Sanchez EP,Bansal SS,Rafael-Fortney JA
25-0451-82 was used in Flow cytometry/Cell sorting to support important contributions of myeloid MR signaling to skeletal muscle repair in acute and chronic injuries and highlight the useful information gained from cell-specific genetic knockouts to delineate mechanisms of pharmacological efficacy.
Tue Mar 01 00:00:00 EST 2022
RAGE Inhibitors as Alternatives to Dexamethasone for Managing Cerebral Edema Following Brain Tumor Surgery.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Liu S,Song Y,Zhang IY,Zhang L,Gao H,Su Y,Yang Y,Yin S,Zheng Y,Ren L,Yin HH,Pillai R,Nath A,Medina EF,Cosgrove PA,Bild AH,Badie B
25-0451-82 was used in Flow cytometry/Cell sorting to study the role of the receptor for advanced glycation end products (RAGE) and its ligands on inflammatory responses to neurosurgical injury in mice and humans.
Tue Mar 01 00:00:00 EST 2022
Induction of alarmin S100A8/A9 mediates activation of aberrant neutrophils in the pathogenesis of COVID-19.
Cell host & microbe
Guo Q,Zhao Y,Li J,Liu J,Yang X,Guo X,Kuang M,Xia H,Zhang Z,Cao L,Luo Y,Bao L,Wang X,Wei X,Deng W,Wang N,Chen L,Chen J,Zhu H,Gao R,Qin C,Wang X,You F
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed Feb 10 00:00:00 EST 2021
Stage-specific action of Runx1 and GATA3 controls silencing of PU.1 expression in mouse pro-T cells.
The Journal of experimental medicine
Hosokawa H,Koizumi M,Masuhara K,Romero-Wolf M,Tanaka T,Nakayama T,Rothenberg EV
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
Stage-specific action of Runx1 and GATA3 controls silencing of PU.1 expression in mouse pro-T cells.
The Journal of experimental medicine
Hosokawa H,Koizumi M,Masuhara K,Romero-Wolf M,Tanaka T,Nakayama T,Rothenberg EV
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
Uptake and trafficking of different sized PLGA nanoparticles by dendritic cells in imiquimod-induced psoriasis-like mice model.
Acta pharmaceutica Sinica. B
Lin Z,Xi L,Chen S,Tao J,Wang Y,Chen X,Li P,Wang Z,Zheng Y
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Mapping the origin and fate of myeloid cells in distinct compartments of the eye by single-cell profiling.
The EMBO journal
Wieghofer P,Hagemeyer N,Sankowski R,Schlecht A,Staszewski O,Amann L,Gruber M,Koch J,Hausmann A,Zhang P,Boneva S,Masuda T,Hilgendorf I,Goldmann T,Böttcher C,Priller J,Rossi FM,Lange C,Prinz M
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Mar 15 00:00:00 EDT 2021
Ablation of lysozyme M-positive cells prevents aircraft noise-induced vascular damage without improving cerebral side effects.
Basic research in cardiology
Frenis K,Helmstädter J,Ruan Y,Schramm E,Kalinovic S,Kröller-Schön S,Bayo Jimenez MT,Hahad O,Oelze M,Jiang S,Wenzel P,Sommer CJ,Frauenknecht KBM,Waisman A,Gericke A,Daiber A,Münzel T,Steven S
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Apr 30 00:00:00 EDT 2021
Photoreceptor protection by mesenchymal stem cell transplantation identifies exosomal MiR-21 as a therapeutic for retinal degeneration.
Cell death and differentiation
Deng CL,Hu CB,Ling ST,Zhao N,Bao LH,Zhou F,Xiong YC,Chen T,Sui BD,Yu XR,Hu CH
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Mar 01 00:00:00 EST 2021
Loss of p53 in mesenchymal stem cells promotes alteration of bone remodeling through negative regulation of osteoprotegerin.
Cell death and differentiation
Velletri T,Huang Y,Wang Y,Li Q,Hu M,Xie N,Yang Q,Chen X,Chen Q,Shou P,Gan Y,Candi E,Annicchiarico-Petruzzelli M,Agostini M,Yang H,Melino G,Shi Y,Wang Y
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Decreased antiviral immune response within the central nervous system of aged mice is associated with increased lethality of West Nile virus encephalitis.
Aging cell
Funk KE,Arutyunov AD,Desai P,White JP,Soung AL,Rosen SF,Diamond MS,Klein RS
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Sun Aug 01 00:00:00 EDT 2021
Anti-adipogenic signals at the onset of obesity-related inflammation in white adipose tissue.
Cellular and molecular life sciences : CMLS
Caputo T,Tran VDT,Bararpour N,Winkler C,Aguileta G,Trang KB,Giordano Attianese GMP,Wilson A,Thomas A,Pagni M,Guex N,Desvergne B,Gilardi F
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Anti-adipogenic signals at the onset of obesity-related inflammation in white adipose tissue.
Cellular and molecular life sciences : CMLS
Caputo T,Tran VDT,Bararpour N,Winkler C,Aguileta G,Trang KB,Giordano Attianese GMP,Wilson A,Thomas A,Pagni M,Guex N,Desvergne B,Gilardi F
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
RANKL from bone marrow adipose lineage cells promotes osteoclast formation and bone loss.
EMBO reports
Hu Y,Li X,Zhi X,Cong W,Huang B,Chen H,Wang Y,Li Y,Wang L,Fang C,Guo J,Liu Y,Cui J,Cao L,Weng W,Zhou Q,Wang S,Chen X,Su J
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Macrophage polarization by MSC-derived CXCL12 determines tumor growth.
Cellular & molecular biology letters
Babazadeh S,Nassiri SM,Siavashi V,Sahlabadi M,Hajinasrollah M,Zamani-Ahmadmahmudi M
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Sat Jun 26 00:00:00 EDT 2021
The effects of postmortem delay on mouse and human microglia gene expression.
Glia
Heng Y,Dubbelaar ML,Marie SKN,Boddeke EWGM,Eggen BJL
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Intrinsic DNA damage repair deficiency results in progressive microglia loss and replacement.
Glia
Zhang X,Heng Y,Kooistra SM,van Weering HRJ,Brummer ML,Gerrits E,Wesseling EM,Brouwer N,Nijboer TW,Dubbelaar ML,Boddeke EWGM,Eggen BJL
25-0451 was used in Flow cytometry/Cell sorting to study when Ercc1 was specifically deleted from Cx3cr1-expressing cells, changes in microglia morphology and immune responses at different times after deletion were determined.
Mon Mar 01 00:00:00 EST 2021
Intrinsic DNA damage repair deficiency results in progressive microglia loss and replacement.
Glia
Zhang X,Heng Y,Kooistra SM,van Weering HRJ,Brummer ML,Gerrits E,Wesseling EM,Brouwer N,Nijboer TW,Dubbelaar ML,Boddeke EWGM,Eggen BJL
25-0451 was used in Flow cytometry/Cell sorting to study when Ercc1 was specifically deleted from Cx3cr1-expressing cells, changes in microglia morphology and immune responses at different times after deletion were determined.
Mon Mar 01 00:00:00 EST 2021
Intercellular Interactions of an Adipogenic CXCL12-Expressing Stromal Cell Subset in Murine Bone Marrow.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Matsushita Y,Chu AKY,Ono W,Welch JD,Ono N
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Jun 01 00:00:00 EDT 2021
Macrophage LAMTOR1 Deficiency Prevents Dietary Obesity and Insulin Resistance Through Inflammation-Induced Energy Expenditure.
Frontiers in cell and developmental biology
Ying L,Zhang M,Ma X,Si Y,Li X,Su J,Yin J,Bao Y
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Jun 08 00:00:00 EDT 2021
Exploiting a Rose Bengal-bearing, oxygen-producing nanoparticle for SDT and associated immune-mediated therapeutic effects in the treatment of pancreatic cancer.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
Nicholas D,Nesbitt H,Farrell S,Logan K,McMullin E,Gillan T,Kelly P,O'Rourke D,Porter S,Thomas K,O'Hagan BMG,Nomikou N,Callan B,Callan JF,McHale AP
25-0451-82 was used in Flow cytometry/Cell sorting to describe a robust means of preparing a pH-sensitive polymethacrylate-coated CaO2 nanoparticle that is capable of transiently alleviating tumour hypoxia.
Tue Jun 01 00:00:00 EDT 2021
Alterations of macrophage and neutrophil content in skeletal muscle of aged versus young mice.
Muscle & nerve
Kawanishi N,Machida S
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Construction of a 3D brain extracellular matrix model to study the interaction between microglia and T cells in co-culture.
The European journal of neuroscience
Frühauf M,Zeitschel U,Höfling C,Ullm F,Rabiger FV,Alber G,Pompe T,Müller U,Roßner S
25-0451 was used in Flow cytometry/Cell sorting to indicate that biomimetic 3D matrices allow for co-cultivation and activation of primary microglia and T cells and provide useful tools to study their interaction in vitro.
Tue Jun 01 00:00:00 EDT 2021
Differential activation of Ca2+ influx channels modulate stem cell potency, their proliferation/viability and tissue regeneration.
NPJ Regenerative medicine
Ahamad N,Sun Y,Nascimento Da Conceicao V,Xavier Paul Ezhilan CRD,Natarajan M,Singh BB
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed Oct 20 00:00:00 EDT 2021
Suppression of mucosal Th17 memory responses by acellular pertussis vaccines enhances nasal Bordetella pertussis carriage.
NPJ vaccines
Dubois V,Chatagnon J,Thiriard A,Bauderlique-Le Roy H,Debrie AS,Coutte L,Locht C
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Jan 08 00:00:00 EST 2021
Synergistic immunotherapy of glioblastoma by dual targeting of IL-6 and CD40.
Nature communications
Yang F,He Z,Duan H,Zhang D,Li J,Yang H,Dorsey JF,Zou W,Nabavizadeh SA,Bagley SJ,Abdullah K,Brem S,Zhang L,Xu X,Byrne KT,Vonderheide RH,Gong Y,Fan Y
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Jun 08 00:00:00 EDT 2021
The effect of fingolimod on regulatory T cells in a mouse model of brain ischaemia.
Journal of neuroinflammation
Malone K,Diaz Diaz AC,Shearer JA,Moore AC,Waeber C
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Sat Jan 30 00:00:00 EST 2021
NOX4 regulates macrophage apoptosis resistance to induce fibrotic progression.
The Journal of biological chemistry
Larson-Casey JL,Gu L,Kang J,Dhyani A,Carter AB
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Jul 01 00:00:00 EDT 2021
The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism.
eLife
Roy A,Tomaz da Silva M,Bhat R,Bohnert KR,Iwawaki T,Kumar A
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Nov 23 00:00:00 EST 2021
A decrease in NAD+ contributes to the loss of osteoprogenitors and bone mass with aging.
NPJ aging and mechanisms of disease
Kim HN,Ponte F,Warren A,Ring R,Iyer S,Han L,Almeida M
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Therapeutic Potential of Mesenchymal Stem Cells in a Pre-Clinical Model of Diabetic Kidney Disease and Obesity.
International journal of molecular sciences
Sávio-Silva C,Soinski-Sousa PE,Simplício-Filho A,Bastos RMC,Beyerstedt S,Rangel ÉB
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Feb 04 00:00:00 EST 2021
Use of a Self-Delivering Anti-CCL3 FANA Oligonucleotide as an Innovative Approach to Target Inflammation after Spinal Cord Injury.
eNeuro
Pelisch N,Rosas Almanza J,Stehlik KE,Aperi BV,Kroner A
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Jun 18 00:00:00 EDT 2021
T cell-depleting nanoparticles ameliorate bone loss by reducing activated T cells and regulating the Treg/Th17 balance.
Bioactive materials
Yang X,Zhou F,Yuan P,Dou G,Liu X,Liu S,Wang X,Jin R,Dong Y,Zhou J,Lv Y,Deng Z,Liu S,Chen X,Han Y,Jin Y
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Oct 01 00:00:00 EDT 2021
Regulatory T-cells inhibit microglia-induced pain hypersensitivity in female mice.
eLife
Kuhn JA,Vainchtein ID,Braz J,Hamel K,Bernstein M,Craik V,Dahlgren MW,Ortiz-Carpena J,Molofsky AB,Molofsky AV,Basbaum AI
25-0451-82 was used in Flow Cytometry to conclude that sexual dimorphism in the contribution of microglia to pain results from Treg-mediated suppression of microglial activation and pain hypersensitivity in female mice.
Fri Oct 15 00:00:00 EDT 2021
Regulatory T-cells inhibit microglia-induced pain hypersensitivity in female mice.
eLife
Kuhn JA,Vainchtein ID,Braz J,Hamel K,Bernstein M,Craik V,Dahlgren MW,Ortiz-Carpena J,Molofsky AB,Molofsky AV,Basbaum AI
25-0451-82 was used in Flow Cytometry to conclude that sexual dimorphism in the contribution of microglia to pain results from Treg-mediated suppression of microglial activation and pain hypersensitivity in female mice.
Fri Oct 15 00:00:00 EDT 2021
Placenta-Expanded Stromal Cell Therapy in a Rodent Model of Simulated Weightlessness.
Cells
Rubinstein L,Paul AM,Houseman C,Abegaz M,Tabares Ruiz S,O'Neil N,Kunis G,Ofir R,Cohen J,Ronca AE,Globus RK,Tahimic CGT
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Apr 19 00:00:00 EDT 2021
Apoptotic vesicles restore liver macrophage homeostasis to counteract type 2 diabetes.
Journal of extracellular vesicles
Zheng C,Sui B,Zhang X,Hu J,Chen J,Liu J,Wu D,Ye Q,Xiang L,Qiu X,Liu S,Deng Z,Zhou J,Liu S,Shi S,Jin Y
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
Distinct skeletal stem cell types orchestrate long bone skeletogenesis.
eLife
Ambrosi TH,Sinha R,Steininger HM,Hoover MY,Murphy MP,Koepke LS,Wang Y,Lu WJ,Morri M,Neff NF,Weissman IL,Longaker MT,Chan CK
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Jul 19 00:00:00 EDT 2021
Integrated OMICs unveil the bone-marrow microenvironment in human leukemia.
Cell reports
Passaro D,Garcia-Albornoz M,Diana G,Chakravarty P,Ariza-McNaughton L,Batsivari A,Borràs-Eroles C,Abarrategi A,Waclawiczek A,Ombrato L,Malanchi I,Gribben J,Bonnet D
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue May 11 00:00:00 EDT 2021
PTENα functions as an immune suppressor and promotes immune resistance in PTEN-mutant cancer.
Nature communications
Sun Y,Lu D,Yin Y,Song J,Liu Y,Hao W,Qi F,Zhang G,Zhang X,Liu L,Lin Z,Liang H,Zhao X,Jin Y,Yin Y
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Aug 26 00:00:00 EDT 2021
Cardiac-derived TGF-β1 confers resistance to diet-induced obesity through the regulation of adipocyte size and function.
Molecular metabolism
Longenecker JZ,Petrosino JM,Martens CR,Hinger SA,Royer CJ,Dorn LE,Branch DA,Serrano J,Stanford KI,Kyriazis GA,Baskin KK,Accornero F
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed Dec 01 00:00:00 EST 2021
Cardiac-derived TGF-β1 confers resistance to diet-induced obesity through the regulation of adipocyte size and function.
Molecular metabolism
Longenecker JZ,Petrosino JM,Martens CR,Hinger SA,Royer CJ,Dorn LE,Branch DA,Serrano J,Stanford KI,Kyriazis GA,Baskin KK,Accornero F
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed Dec 01 00:00:00 EST 2021
Determining the effect of aging, recovery time, and post-stroke memantine treatment on delayed thalamic gliosis after cortical infarct.
Scientific reports
Kim GS,Stephenson JM,Al Mamun A,Wu T,Goss MG,Min JW,Li J,Liu F,Marrelli SP
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Jun 15 00:00:00 EDT 2021
Cytochrome P450 26A1 Modulates the Polarization of Uterine Macrophages During the Peri-Implantation Period.
Frontiers in immunology
Ji WH,Li DD,Wei DP,Gu AQ,Yang Y,Peng JP
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Feb 10 00:00:00 EST 2022
A molybdenum oxide-based degradable nanosheet for combined chemo-photothermal therapy to improve tumor immunosuppression and suppress distant tumors and lung metastases.
Journal of nanobiotechnology
Qiu N,Yang X,Zhang Y,Zhang J,Ji J,Zhang Y,Kong X,Xi Y,Liu D,Ye L,Zhai G
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Sun Dec 19 00:00:00 EST 2021
Visceral adipose tissue imparts peripheral macrophage influx into the hypothalamus.
Journal of neuroinflammation
Chen KE,Lainez NM,Nair MG,Coss D
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Jun 21 00:00:00 EDT 2021
Quantitative in vivo assessment of amyloid-beta phagocytic capacity in an Alzheimer's disease mouse model.
STAR protocols
Lau SF,Wu W,Seo H,Fu AKY,Ip NY
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Mar 19 00:00:00 EDT 2021
Bone marrow sinusoidal endothelium controls terminal erythroid differentiation and reticulocyte maturation.
Nature communications
Heil J,Olsavszky V,Busch K,Klapproth K,de la Torre C,Sticht C,Sandorski K,Hoffmann J,Schönhaber H,Zierow J,Winkler M,Schmid CD,Staniczek T,Daniels DE,Frayne J,Metzgeroth G,Nowak D,Schneider S,Neumaier M,Weyer V,Groden C,Gröne HJ,Richter K,Mogler C,Taketo MM,Schledzewski K,Géraud C,Goerdt S,Koch PS
25-0451-82 was used in Flow Cytometry to show that bone marrow sinusoidal endothelial cells actively control erythropoiesis.
Mon Nov 29 00:00:00 EST 2021
Mice with induced pulmonary morbidities display severe lung inflammation and mortality following exposure to SARS-CoV-2.
JCI insight
Falach R,Bar-On L,Lazar S,Kadar T,Mazor O,Aftalion M,Gur D,Evgy Y,Shifman O,Aminov T,Israeli O,Cohen-Gihon I,Zaide G,Gutman H,Vagima Y,Makdasi E,Stein D,Rosenfeld R,Alcalay R,Zahavy E,Levy H,Glinert I,Ben-Shmuel A,Israely T,Melamed S,Politi B,Achdout H,Yitzhaki S,Kronman C,Sabo T
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Jun 22 00:00:00 EDT 2021
LMO2 is essential to maintain the ability of progenitors to differentiate into T-cell lineage in mice.
eLife
Hirano KI,Hosokawa H,Koizumi M,Endo Y,Yahata T,Ando K,Hozumi K
25-0451-82 was used in Flow Cytometry to highlight LMO2 as a crucial player in the survival and maintenance of T-lineage potential in T-cell progenitors via the regulation of the expression of Bcl11a and Tcf7.
Thu Aug 12 00:00:00 EDT 2021
Novel TGFβ Inhibitors Ameliorate Oral Squamous Cell Carcinoma Progression and Improve the Antitumor Immune Response of Anti-PD-L1 Immunotherapy.
Molecular cancer therapeutics
Ludwig N,Wieteska Ł,Hinck CS,Yerneni SS,Azambuja JH,Bauer RJ,Reichert TE,Hinck AP,Whiteside TL
25-0451-82 was used in Flow cytometry/Cell sorting to study two novel TGFβ inhibitors as mono or combinatorial therapy with anti-PD-L1 antibodies (α-PD-L1 Ab) in a murine oral squamous cell carcinoma (OSCC) model to demonstrate that the inhibitors promote antitumor immune responses, alone and in combination with α-PD-L1 Abs.
Tue Jun 01 00:00:00 EDT 2021
Assessing Lupus-Like Disease in Murine Model Systems.
Current protocols
Lee HY,Celhar T,Fairhurst AM
25-0451-82 was used in Flow Cytometry to evaluate the underlying immunological features of the disease, as a more sensitive strategy to understand the disease itself and the mechanisms of potential novel therapeutics.
Mon Nov 01 00:00:00 EDT 2021
Protocols for endothelial cell isolation from mouse tissues: brain, choroid, lung, and muscle.
STAR protocols
Conchinha NV,Sokol L,Teuwen LA,Veys K,Dumas SJ,Meta E,García-Caballero M,Geldhof V,Chen R,Treps L,Borri M,de Zeeuw P,Falkenberg KD,Dubois C,Parys M,de Rooij LPMH,Rohlenova K,Goveia J,Schoonjans L,Dewerchin M,Eelen G,Li X,Kalucka J,Carmeliet P
25-0451-82 was used in Flow Cytometry to describe a rapid and reproducible blood vessel EC purification established for scRNA sequencing from murine tissues using mechanical and enzymatic digestion.
Fri Sep 17 00:00:00 EDT 2021
VISTA regulates microglia homeostasis and myelin phagocytosis, and is associated with MS lesion pathology.
Acta neuropathologica communications
Borggrewe M,Kooistra SM,Wesseling EM,Gierschek FL,Brummer ML,Nowak EC,Medeiros-Furquim T,Otto TA,Lee SW,Noelle RJ,Eggen BJL,Laman JD
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Immunohistochemistry
Tue May 18 00:00:00 EDT 2021
Hlf Expression Marks Early Emergence of Hematopoietic Stem Cell Precursors With Adult Repopulating Potential and Fate.
Frontiers in cell and developmental biology
Tang W,He J,Huang T,Bai Z,Wang C,Wang H,Yang R,Ni Y,Hou J,Wang J,Zhou J,Yao Y,Gong Y,Hou S,Liu B,Lan Y
25-0451-82 was used in Flow cytometry/Cell sorting to develop an Hlf-tdTomato reporter mouse model and detected Hlf-tdTomato expression exclusively in the hematopoietic cells including part of the immunophenotypic CD45- and CD45+ pre-HSCs in the embryonic day (E) 10.5 AGM region.
Fri Oct 01 00:00:00 EDT 2021
Epinephrine Production in Th17 Cells and Experimental Autoimmune Encephalitis.
Frontiers in immunology
Yang P,Tian H,Zou YR,Chambon P,Ichinose H,Honig G,Diamond B,Kim SJ
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Systemic administration of β-glucan induces immune training in microglia.
Journal of neuroinflammation
Heng Y,Zhang X,Borggrewe M,van Weering HRJ,Brummer ML,Nijboer TW,Joosten LAB,Netea MG,Boddeke EWGM,Laman JD,Eggen BJL
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Feb 22 00:00:00 EST 2021
Single-Cell Transcriptome Atlas of Murine Endothelial Cells.
Cell
Kalucka J,de Rooij LPMH,Goveia J,Rohlenova K,Dumas SJ,Meta E,Conchinha NV,Taverna F,Teuwen LA,Veys K,García-Caballero M,Khan S,Geldhof V,Sokol L,Chen R,Treps L,Borri M,de Zeeuw P,Dubois C,Karakach TK,Falkenberg KD,Parys M,Yin X,Vinckier S,Du Y,Fenton RA,Schoonjans L,Dewerchin M,Eelen G,Thienpont B,Lin L,Bolund L,Li X,Luo Y,Carmeliet P
25-0451-82 was used in Flow Cytometry to create a detailed atlas of >32,000 single-endothelial cell transcriptomes.
Thu Feb 20 00:00:00 EST 2020
Macrophages Maintain Epithelium Integrity by Limiting Fungal Product Absorption.
Cell
Chikina AS,Nadalin F,Maurin M,San-Roman M,Thomas-Bonafos T,Li XV,Lameiras S,Baulande S,Henri S,Malissen B,Lacerda Mariano L,Barbazan J,Blander JM,Iliev ID,Matic Vignjevic D,Lennon-Duménil AM
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Oct 15 00:00:00 EDT 2020
The Cytokine TGF-β Induces Interleukin-31 Expression from Dermal Dendritic Cells to Activate Sensory Neurons and Stimulate Wound Itching.
Immunity
Xu J,Zanvit P,Hu L,Tseng PY,Liu N,Wang F,Liu O,Zhang D,Jin W,Guo N,Han Y,Yin J,Cain A,Hoon MA,Wang S,Chen W
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Aug 18 00:00:00 EDT 2020
Osteopontin Expression Identifies a Subset of Recruited Macrophages Distinct from Kupffer Cells in the Fatty Liver.
Immunity
Remmerie A,Martens L,Thoné T,Castoldi A,Seurinck R,Pavie B,Roels J,Vanneste B,De Prijck S,Vanhockerhout M,Binte Abdul Latib M,Devisscher L,Hoorens A,Bonnardel J,Vandamme N,Kremer A,Borghgraef P,Van Vlierberghe H,Lippens S,Pearce E,Saeys Y,Scott CL
25-0451 was used in Flow cytometry/Cell sorting to highlight considerable heterogeneity within the macrophage pool and suggest a need for more specific macrophage targeting strategies in metabolic-associated fatty liver disease (MAFLD).
Tue Sep 15 00:00:00 EDT 2020
Microglial microRNAs mediate sex-specific responses to tau pathology.
Nature neuroscience
Kodama L,Guzman E,Etchegaray JI,Li Y,Sayed FA,Zhou L,Zhou Y,Zhan L,Le D,Udeochu JC,Clelland CD,Cheng Z,Yu G,Li Q,Kosik KS,Gan L
25-0451 was used in Flow cytometry/Cell sorting to demonstrate that microglial microRNA expression differs in males and females and that loss of microRNAs leads to sex-specific changes in the microglial transcriptome and tau pathology in mice.
Sat Feb 01 00:00:00 EST 2020
Exposure to diesel exhaust particles increases susceptibility to invasive pneumococcal disease.
The Journal of allergy and clinical immunology
Shears RK,Jacques LC,Naylor G,Miyashita L,Khandaker S,Lebre F,Lavelle EC,Grigg J,French N,Neill DR,Kadioglu A
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Modulation of the functions of myeloid-derived suppressor cells : a new strategy of hydrogen sulfide anti-cancer effects.
British journal of pharmacology
De Cicco P,Ercolano G,Rubino V,Terrazzano G,Ruggiero G,Cirino G,Ianaro A
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Sat Feb 01 00:00:00 EST 2020
Critical role of OX40 in drug-induced acute liver injury.
British journal of pharmacology
Zhang C,Jin H,Wang Y,Li C,Zhao X,Li Y,Shi W,Tian Y,Xu H,Tian D,Liu K,Jia J,Sun G,Zhang D
25-0451-82 was used in Flow Cytometry to show that OX40 is a key molecule that promotes both pro-inflammatory macrophage and CD4+ T-cell function, exacerbating paracetamol-induced liver injury.
Wed Jul 01 00:00:00 EDT 2020
Notch2 complements Notch1 to mediate inductive signaling that initiates early T cell development.
The Journal of cell biology
Romero-Wolf M,Shin B,Zhou W,Koizumi M,Rothenberg EV,Hosokawa H
25-0451 was used in Flow cytometry/Cell sorting to define a distinct mechanism of Notch signal response that distinguishes the initial stages of murine T cell development.
Mon Oct 05 00:00:00 EDT 2020
Membrane expression of the estrogen receptor ERα is required for intercellular communications in the mammary epithelium.
Development (Cambridge, England)
Gagniac L,Rusidzé M,Boudou F,Cagnet S,Adlanmerini M,Jeannot P,Gaide N,Giton F,Besson A,Weyl A,Gourdy P,Raymond-Letron I,Arnal JF,Brisken C,Lenfant F
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed Mar 11 00:00:00 EDT 2020
A genetic system for tissue-specific inhibition of cell proliferation.
Development (Cambridge, England)
Pu W,Han X,He L,Li Y,Huang X,Zhang M,Lv Z,Yu W,Wang QD,Cai D,Wang J,Sun R,Fei J,Ji Y,Nie Y,Zhou B
25-0451-82 was used in Immunohistochemistry (PFA fixed) to validate the use of ip21-GFP mice as a new genetic tool for cell lineage-specific inhibition of cell proliferation in vivo.
Mon Feb 17 00:00:00 EST 2020
Dysfunction of B Cell Leading to Failure of Immunoglobulin Response Is Ameliorated by Dietary Silk Peptide in 14-Month-Old C57BL/6 Mice.
Frontiers in nutrition
Chei S,Oh HJ,Lee K,Jin H,Lee JY,Lee BY
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Dec 18 00:00:00 EST 2020
Sema3A and HIF1α co-overexpressed iPSC-MSCs/HA scaffold facilitates the repair of calvarial defect in a mouse model.
Journal of cellular physiology
Li J,Wang T,Li C,Wang Z,Wang P,Zheng L
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Detection of Synaptic Proteins in Microglia by Flow Cytometry.
Frontiers in molecular neuroscience
Brioschi S,d'Errico P,Amann LS,Janova H,Wojcik SM,Meyer-Luehmann M,Rajendran L,Wieghofer P,Paolicelli RC,Biber K
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Nov 03 00:00:00 EST 2020
Extracellular HMGB-1 activates inflammatory signaling in tendon cells and tissues.
Therapeutic advances in chronic disease
Zhang C,Gu X,Zhao G,Wang W,Shao J,Zhu J,Yuan T,Sun J,Nie D,Zhou Y
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Sun Apr 17 00:00:00 EDT 2022
Resveratrol rescues TNF‑α‑induced inhibition of osteogenesis in human periodontal ligament stem cells via the ERK1/2 pathway.
Molecular medicine reports
Yuan J,Wang X,Ma D,Gao H,Zheng D,Zhang J
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers.
Nature communications
Okazaki K,Anzawa H,Liu Z,Ota N,Kitamura H,Onodera Y,Alam MM,Matsumaru D,Suzuki T,Katsuoka F,Tadaka S,Motoike I,Watanabe M,Hayasaka K,Sakurada A,Okada Y,Yamamoto M,Suzuki T,Kinoshita K,Sekine H,Motohashi H
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Nov 20 00:00:00 EST 2020
Eosinophils improve cardiac function after myocardial infarction.
Nature communications
Liu J,Yang C,Liu T,Deng Z,Fang W,Zhang X,Li J,Huang Q,Liu C,Wang Y,Yang D,Sukhova GK,Lindholt JS,Diederichsen A,Rasmussen LM,Li D,Newton G,Luscinskas FW,Liu L,Libby P,Wang J,Guo J,Shi GP
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed Dec 16 00:00:00 EST 2020
Ly6cLo non-classical monocytes promote resolution of rhesus rotavirus-mediated perinatal hepatic inflammation.
Scientific reports
Alkhani A,Levy CS,Tsui M,Rosenberg KA,Polovina K,Mattis AN,Mack M,Van Dyken S,Wang BM,Maher JJ,Nijagal A
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Apr 28 00:00:00 EDT 2020
Stromal CCL2 Signaling Promotes Mammary Tumor Fibrosis through Recruitment of Myeloid-Lineage Cells.
Cancers
Kuziel G,Thompson V,D'Amato JV,Arendt LM
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Jul 28 00:00:00 EDT 2020
Small GTPase RAB6 deficiency promotes alveolar progenitor cell renewal and attenuates PM2.5-induced lung injury and fibrosis.
Cell death & disease
Yang L,Liu G,Li X,Xia Z,Wang Y,Lin W,Zhang W,Zhang W,Li X
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Sun Oct 04 00:00:00 EDT 2020
A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation.
Nature communications
Kim JM,Yang YS,Park KH,Ge X,Xu R,Li N,Song M,Chun H,Bok S,Charles JF,Filhol-Cochet O,Boldyreff B,Dinter T,Yu PB,Kon N,Gu W,Takarada T,Greenblatt MB,Shim JH
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri May 08 00:00:00 EDT 2020
Analysis of the immune response to sciatic nerve injury identifies efferocytosis as a key mechanism of nerve debridement.
eLife
Kalinski AL,Yoon C,Huffman LD,Duncker PC,Kohen R,Passino R,Hafner H,Johnson C,Kawaguchi R,Carbajal KS,Jara JS,Hollis E,Geschwind DH,Segal BM,Giger RJ
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed Dec 02 00:00:00 EST 2020
Resolvin D1 supports skeletal myofiber regeneration via actions on myeloid and muscle stem cells.
JCI insight
Markworth JF,Brown LA,Lim E,Floyd C,Larouche J,Castor-Macias JA,Sugg KB,Sarver DC,Macpherson PC,Davis C,Aguilar CA,Maddipati KR,Brooks SV
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Sep 17 00:00:00 EDT 2020
Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations.
Journal of neuroinflammation
Lowe PP,Morel C,Ambade A,Iracheta-Vellve A,Kwiatkowski E,Satishchandran A,Furi I,Cho Y,Gyongyosi B,Catalano D,Lefebvre E,Fischer L,Seyedkazemi S,Schafer DP,Szabo G
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Oct 09 00:00:00 EDT 2020
Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations.
Journal of neuroinflammation
Lowe PP,Morel C,Ambade A,Iracheta-Vellve A,Kwiatkowski E,Satishchandran A,Furi I,Cho Y,Gyongyosi B,Catalano D,Lefebvre E,Fischer L,Seyedkazemi S,Schafer DP,Szabo G
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Oct 09 00:00:00 EDT 2020
Delayed microglial depletion after spinal cord injury reduces chronic inflammation and neurodegeneration in the brain and improves neurological recovery in male mice.
Theranostics
Li Y,Ritzel RM,Khan N,Cao T,He J,Lei Z,Matyas JJ,Sabirzhanov B,Liu S,Li H,Stoica BA,Loane DJ,Faden AI,Wu J
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Jun 01 00:00:00 EDT 2021
Inhibition of formyl peptide receptors improves the outcome in a mouse model of Alzheimer disease.
Journal of neuroinflammation
Schröder N,Schaffrath A,Welter JA,Putzka T,Griep A,Ziegler P,Brandt E,Samer S,Heneka MT,Kaddatz H,Zhan J,Kipp E,Pufe T,Tauber SC,Kipp M,Brandenburg LO
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Apr 24 00:00:00 EDT 2020
Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target.
JCI insight
Pierini S,Tanyi JL,Simpkins F,George E,Uribe-Herranz M,Drapkin R,Burger R,Morgan MA,Facciabene A
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Aug 20 00:00:00 EDT 2020
Butyrophilin-like proteins display combinatorial diversity in selecting and maintaining signature intraepithelial γδ T cell compartments.
Nature communications
Jandke A,Melandri D,Monin L,Ushakov DS,Laing AG,Vantourout P,East P,Nitta T,Narita T,Takayanagi H,Feederle R,Hayday A
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Jul 28 00:00:00 EDT 2020
Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models.
Communications biology
Waaler J,Mygland L,Tveita A,Strand MF,Solberg NT,Olsen PA,Aizenshtadt A,Fauskanger M,Lund K,Brinch SA,Lycke M,Dybing E,Nygaard V,Bøe SL,Heintz KM,Hovig E,Hammarström C,Corthay A,Krauss S
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Apr 24 00:00:00 EDT 2020
PPARγ inhibition boosts efficacy of PD-L1 Checkpoint Blockade Immunotherapy against Murine Melanoma in a sexually dimorphic manner.
International journal of biological sciences
Wu B,Sun X,Yuan B,Ge F,Gupta HB,Chiang HC,Li J,Hu Y,Curiel TJ,Li R
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Aug 23 00:00:00 EDT 2021
A Synthetic Small Molecule F240B Decreases NLRP3 Inflammasome Activation by Autophagy Induction.
Frontiers in immunology
Wu CH,Gan CH,Li LH,Chang JC,Chen ST,Menon MP,Cheng SM,Yang SP,Ho CL,Chernikov OV,Lin CH,Lam Y,Hua KF
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed Jun 23 00:00:00 EDT 2021
CNS Immune Profiling in a Dengue Virus-Infected Immunocompetent Outbred ICR Mice Strain.
Frontiers in cellular and infection microbiology
Shen TJ,Chen CL,Jhan MK,Tseng PC,Lin CF
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Jun 17 00:00:00 EDT 2021
Apoptotic bodies derived from mesenchymal stem cells promote cutaneous wound healing via regulating the functions of macrophages.
Stem cell research & therapy
Liu J,Qiu X,Lv Y,Zheng C,Dong Y,Dou G,Zhu B,Liu A,Wang W,Zhou J,Liu S,Liu S,Gao B,Jin Y
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Nov 27 00:00:00 EST 2020
Phosphatase SHP1 impedes mesenchymal stromal cell immunosuppressive capacity modulated by JAK1/STAT3 and P38 signals.
Cell & bioscience
Jiang M,Ye J,Wang X,Li N,Wang Y,Shi Y
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Apr 14 00:00:00 EDT 2022
Defining the role of pulmonary endothelial cell heterogeneity in the response to acute lung injury.
eLife
Niethamer TK,Stabler CT,Leach JP,Zepp JA,Morley MP,Babu A,Zhou S,Morrisey EE
25-0451 was used in Flow cytometry/Cell sorting to identify that different subtypes of endothelial cells exist in capillaries, and that some may be able to perform slightly different jobs during lung recovery.
Mon Feb 24 00:00:00 EST 2020
Chronic expression of p16INK4a in the epidermis induces Wnt-mediated hyperplasia and promotes tumor initiation.
Nature communications
Azazmeh N,Assouline B,Winter E,Ruppo S,Nevo Y,Maly A,Meir K,Witkiewicz AK,Cohen J,Rizou SV,Pikarsky E,Luxenburg C,Gorgoulis VG,Ben-Porath I
25-0451 was used in Flow cytometry/Cell sorting to investigate the effect of prolonged expression of transgenic p16INK4a in the mouse epidermis and the pathways involved in this effect.
Mon Jun 01 00:00:00 EDT 2020
Enhancing chemotherapy response through augmented synthetic lethality by co-targeting nucleotide excision repair and cell-cycle checkpoints.
Nature communications
Kong YW,Dreaden EC,Morandell S,Zhou W,Dhara SS,Sriram G,Lam FC,Patterson JC,Quadir M,Dinh A,Shopsowitz KE,Varmeh S,Yilmaz ÖH,Lippard SJ,Reinhardt HC,Hemann MT,Hammond PT,Yaffe MB
25-0451 was used in Flow cytometry/Cell sorting to describe the concept of augmented synthetic lethality (ASL): depletion of a third gene product enhances a pre-existing synthetic lethal combination.
Mon Aug 17 00:00:00 EDT 2020
Macrophage NCOR1 Deficiency Ameliorates Myocardial Infarction and Neointimal Hyperplasia in Mice.
Journal of the American Heart Association
Du LJ,Sun JY,Zhang WC,Wang YL,Zhu H,Liu T,Gao MZ,Zheng C,Zhang YY,Liu Y,Liu Y,Shao S,Zhang XQ,Leng Q,Auwerx J,Duan SZ
25-0451 was used in Flow cytometry/Cell sorting to demonstrate that NCOR1 is a critical regulator of macrophage inflammation and proliferation and that deficiency of NCOR1 in macrophages attenuates MI and neointimal hyperplasia.
Tue Aug 04 00:00:00 EDT 2020
SPHK2-Generated S1P in CD11b+ Macrophages Blocks STING to Suppress the Inflammatory Function of Alveolar Macrophages.
Cell reports
Joshi JC,Joshi B,Rochford I,Rayees S,Akhter MZ,Baweja S,Chava KR,Tauseef M,Abdelkarim H,Natarajan V,Gaponenko V,Mehta D
25-0451 was used in Flow cytometry/Cell sorting to demonstrate the anti-inflammatory regulation of monocyte-derived macrophages by acting on type 1 interferon gene signalling.
Tue Mar 24 00:00:00 EDT 2020
CD103+ cDC1 and endogenous CD8+ T cells are necessary for improved CD40L-overexpressing CAR T cell antitumor function.
Nature communications
Kuhn NF,Lopez AV,Li X,Cai W,Daniyan AF,Brentjens RJ
25-0451 was used in Flow cytometry/Cell sorting to demonstrate the stimulatory effect of CD40L-overexpressing CAR T cells on innate and adaptive immune cells, and provide a rationale for using CD40L-overexpressing CAR T cells to improve immunotherapy responses.
Wed Dec 02 00:00:00 EST 2020
The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development.
Cell reports
Hsiao WY,Jung SM,Tang Y,Haley JA,Li R,Li H,Calejman CM,Sanchez-Gurmaches J,Hung CM,Luciano AK,DeMambro V,Wellen KE,Rosen CJ,Zhu LJ,Guertin DA
25-0451-82 was used in Flow Cytometry to uncover a critical role for mTORC2 in setting SWAT lipid handling capacity.
Tue Oct 06 00:00:00 EDT 2020
Bone metastasis is associated with acquisition of mesenchymal phenotype and immune suppression in a model of spontaneous breast cancer metastasis.
Scientific reports
Monteran L,Ershaid N,Sabah I,Fahoum I,Zait Y,Shani O,Cohen N,Eldar-Boock A,Satchi-Fainaro R,Erez N
25-0451 was used in Flow cytometry/Cell sorting to characterise the intrinsic changes in breast cancer cells that facilitate bone-tropism and found that they acquire mesenchymal and osteomimetic features.
Fri Aug 14 00:00:00 EDT 2020
Mitofusin 2 in Macrophages Links Mitochondrial ROS Production, Cytokine Release, Phagocytosis, Autophagy, and Bactericidal Activity.
Cell reports
Tur J,Pereira-Lopes S,Vico T,Marín EA,Muñoz JP,Hernández-Alvarez M,Cardona PJ,Zorzano A,Lloberas J,Celada A
25-0451 was used in Flow cytometry/Cell sorting to reveal an unexpected contribution of Mfn2 to ROS production and inflammation in macrophages.
Tue Aug 25 00:00:00 EDT 2020
Dynamics of Asymmetric and Symmetric Divisions of Muscle Stem Cells In Vivo and on Artificial Niches.
Cell reports
Evano B,Khalilian S,Le Carrou G,Almouzni G,Tajbakhsh S
25-0451 was used in Flow cytometry/Cell sorting to generate SNAP-tagged histone H3-reporter mice and find that, unlike fly germline stem cells, differential fate outcomes are associated with a symmetric distribution of the H3.1 and H3.3 histone variants in mouse muscle stem cells.
Tue Mar 10 00:00:00 EDT 2020
Osterix-Cre marks distinct subsets of CD45- and CD45+ stromal populations in extra-skeletal tumors with pro-tumorigenic characteristics.
eLife
Ricci B,Tycksen E,Celik H,Belle JI,Fontana F,Civitelli R,Faccio R
25-0451 was used in Flow cytometry/Cell sorting to find Osx transcript and Osx protein expression early during hematopoiesis, in subsets of hematopoietic stem cells and multipotent progenitor populations.
Wed Aug 05 00:00:00 EDT 2020
Distinct Waves from the Hemogenic Endothelium Give Rise to Layered Lymphoid Tissue Inducer Cell Ontogeny.
Cell reports
Simic M,Manosalva I,Spinelli L,Gentek R,Shayan RR,Siret C,Girard-Madoux M,Wang S,de Fabritus L,Verschoor J,Kerdiles YM,Bajenoff M,Stumm R,Golub R,van de Pavert SA
25-0451 was used in Flow cytometry/Cell sorting to identify a major contribution from embryonic hemogenic endothelium, but not the yolk sac, toward LTi progenitors.
Tue Aug 11 00:00:00 EDT 2020
Mesenchymal Stromal Cell-Derived Exosomes Contribute to Epithelial Regeneration in Experimental Inflammatory Bowel Disease.
Cellular and molecular gastroenterology and hepatology
Barnhoorn MC,Plug L,Jonge ESMM,Molenkamp D,Bos E,Schoonderwoerd MJA,Corver WE,van der Meulen-de Jong AE,Verspaget HW,Hawinkels LJAC
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon May 10 00:00:00 EDT 2021
Compartmentalized gut lymph node drainage dictates adaptive immune responses.
Nature
Esterházy D,Canesso MCC,Mesin L,Muller PA,de Castro TBR,Lockhart A,ElJalby M,Faria AMC,Mucida D
25-0451-82 was used in Flow Cytometry to show drainage of gut-draining lymph nodes can resolve conflicting tolerogenic and inflammatory intestinal responses by encouraging antigen targeting to specific gut segments.
Wed May 01 00:00:00 EDT 2019
Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche.
Immunity
Bonnardel J,T'Jonck W,Gaublomme D,Browaeys R,Scott CL,Martens L,Vanneste B,De Prijck S,Nedospasov SA,Kremer A,Van Hamme E,Borghgraef P,Toussaint W,De Bleser P,Mannaerts I,Beschin A,van Grunsven LA,Lambrecht BN,Taghon T,Lippens S,Elewaut D,Saeys Y,Guilliams M
25-0451-82 was used in Flow Cytometry to show that the Kupffer cell niche is composed of stellate cells, hepatocytes, and endothelial cells that together imprint the liver-specific macrophage identity.
Tue Oct 15 00:00:00 EDT 2019
Single-Cell Analysis Reveals Regulatory Gene Expression Dynamics Leading to Lineage Commitment in Early T Cell Development.
Cell systems
Zhou W,Yui MA,Williams BA,Yun J,Wold BJ,Cai L,Rothenberg EV
25-0451 was used in Flow cytometry/Cell sorting to imply that multilineage priming is integral to T cell specification.
Wed Oct 23 00:00:00 EDT 2019
The ROP16III-dependent early immune response determines the subacute CNS immune response and type III Toxoplasma gondii survival.
PLoS pathogens
Tuladhar S,Kochanowsky JA,Bhaskara A,Ghotmi Y,Chandrasekaran S,Koshy AA
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
Distinct Tie2 tyrosine phosphorylation sites dictate phenotypic switching in endothelial progenitor cells.
Journal of cellular physiology
Siavashi V,Nassiri SM,Rahbarghazi R,Mohseni Z,Sharifi AM
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed May 01 00:00:00 EDT 2019
Protumoral bone marrow-derived cells migrate via Gβγ-dependent signaling pathways and exhibit a complex repertoire of RhoGEFs.
Journal of cell communication and signaling
Cervantes-Villagrana RD,Color-Aparicio VM,Reyes-Cruz G,Vázquez-Prado J
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Sat Jun 01 00:00:00 EDT 2019
Antiallodynic Effects of Cannabinoid Receptor 2 (CB2R) Agonists on Retrovirus Infection-Induced Neuropathic Pain.
Pain research & management
Sheng WS,Chauhan P,Hu S,Prasad S,Lokensgard JR
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Dec 16 00:00:00 EST 2019
Antitumor and immunomodulatory effects of a novel multitarget inhibitor, CS2164, in mouse hepatocellular carcinoma models.
Anti-cancer drugs
Zhou Y,Fu C,Kong Y,Pan D,Wang Y,Huang S,Li Z,Ning Z,Lu X,Shan S,Xin L
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
CSF1R antagonism limits local restimulation of antiviral CD8+ T cells during viral encephalitis.
Journal of neuroinflammation
Funk KE,Klein RS
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Jan 31 00:00:00 EST 2019
Autophagy regulates inflammatory programmed cell death via turnover of RHIM-domain proteins.
eLife
Lim J,Park H,Heisler J,Maculins T,Roose-Girma M,Xu M,Mckenzie B,van Lookeren Campagne M,Newton K,Murthy A
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Jul 09 00:00:00 EDT 2019
The microRNAs miR-204 and miR-211 maintain joint homeostasis and protect against osteoarthritis progression.
Nature communications
Huang J,Zhao L,Fan Y,Liao L,Ma PX,Xiao G,Chen D
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Jun 28 00:00:00 EDT 2019
Neural anti-inflammatory action mediated by two types of acetylcholine receptors in the small intestine.
Scientific reports
Kimura H,Imura YK,Tomiyasu H,Mihara T,Kaji N,Ohno K,Unno T,Tanahashi Y,Jan TR,Tsubone H,Ozaki H,Hori M
25-0451 was used in Flow cytometry/Cell sorting to clarify the anti-inflammatory mechanism underlying the serotonin-4 receptor agonist, mosapride citrate-induced anti-inflammatory action on postoperative ileus.
Wed Apr 10 00:00:00 EDT 2019
MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment.
Journal for immunotherapy of cancer
Fang DD,Tang Q,Kong Y,Wang Q,Gu J,Fang X,Zou P,Rong T,Wang J,Yang D,Zhai Y
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Nov 28 00:00:00 EST 2019
Muscularis Propria Macrophages Alter the Proportion of Nitrergic but Not Cholinergic Gastric Myenteric Neurons.
Cellular and molecular gastroenterology and hepatology
Cipriani G,Terhaar ML,Eisenman ST,Ji S,Linden DR,Wright AM,Sha L,Ordog T,Szurszewski JH,Gibbons SJ,Farrugia G
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Jun 04 00:00:00 EDT 2019
Systematic testing and specificity mapping of alloantigen-specific chimeric antigen receptors in regulatory T cells.
JCI insight
Dawson NA,Lamarche C,Hoeppli RE,Bergqvist P,Fung VC,McIver E,Huang Q,Gillies J,Speck M,Orban PC,Bush JW,Mojibian M,Levings MK
25-0451 was used in Flow cytometry/Cell sorting to characterise and test alloantigen-specific chimeric antigen receptors in regulatory T cells.
Thu Mar 21 00:00:00 EDT 2019
Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis.
eLife
Walsh CM,Hill RZ,Schwendinger-Schreck J,Deguine J,Brock EC,Kucirek N,Rifi Z,Wei J,Gronert K,Brem RB,Barton GM,Bautista DM
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Oct 21 00:00:00 EDT 2019
Exposure to Cigarette Smoke Augments Post-ischemic Brain Injury and Inflammation via Mobilization of Neutrophils and Monocytes.
Frontiers in immunology
Li H,Li X,Gao S,Wang D,Gao X,Li Y,Wang X,Cui Z,Ma H,Liu Q,Li M
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2020
Bone-derived Nestin-positive mesenchymal stem cells improve cardiac function via recruiting cardiac endothelial cells after myocardial infarction.
Stem cell research & therapy
Lu D,Liao Y,Zhu SH,Chen QC,Xie DM,Liao JJ,Feng X,Jiang MH,He W
25-0451 was used in Flow cytometry/Cell sorting to show that Nestin is a useful marker for the identification of functional BMSCs and indicate that Nestin+ BMSCs could be a better therapeutic candidate for cardiac repair.
Sat Apr 27 00:00:00 EDT 2019
NLRP3 inflammasome in fibroblasts links tissue damage with inflammation in breast cancer progression and metastasis.
Nature communications
Ershaid N,Sharon Y,Doron H,Raz Y,Shani O,Cohen N,Monteran L,Leider-Trejo L,Ben-Shmuel A,Yassin M,Gerlic M,Ben-Baruch A,Pasmanik-Chor M,Apte R,Erez N
25-0451-82 was used in Flow Cytometry to find that fibroblasts sense damage-associated molecular patterns (DAMPs), and in response activate the NLRP3 inflammasome pathway, resulting in instigation of pro-inflammatory signalling and secretion of IL-1β.
Thu Sep 26 00:00:00 EDT 2019
Frontline Science: Abnormalities in the gut mucosa of non-obese diabetic mice precede the onset of type 1 diabetes.
Journal of leukocyte biology
Miranda MCG,Oliveira RP,Torres L,Aguiar SLF,Pinheiro-Rosa N,Lemos L,Guimarães MA,Reis D,Silveira T,Ferreira Ê,Moreira TG,Cara DC,Maioli TU,Kelsall BL,Carlos D,Faria AMC
25-0451-82 was used in Flow cytometry/Cell sorting to show that disorders in the intestinal mucosa of NOD mice can potentially interfere with the development of T1D due the close relationship between the gut and the pancreas.
Sun Sep 01 00:00:00 EDT 2019
Establishing a Link between Endothelial Cell Metabolism and Vascular Behaviour in a Type 1 Diabetes Mouse Model.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Silva C,Sampaio-Pinto V,Andrade S,Rodrigues I,Costa R,Guerreiro S,Carvalho E,Pinto-do-Ó P,Nascimento DS,Soares R
25-0451 was used in Flow cytometry/Cell sorting to study the angiogenic and metabolic gene expression profile of endothelial cells from a diabetes model.
Wed Apr 03 00:00:00 EDT 2019
FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy.
eLife
Diaz Osterman CJ,Ozmadenci D,Kleinschmidt EG,Taylor KN,Barrie AM,Jiang S,Bean LM,Sulzmaier FJ,Jean C,Tancioni I,Anderson K,Uryu S,Cordasco EA,Li J,Chen XL,Fu G,Ojalill M,Rappu P,Heino J,Mark AM,Xu G,Fisch KM,Kolev VN,Weaver DT,Pachter JA,Győrffy B,McHale MT,Connolly DC,Molinolo A,Stupack DG,Schlaepfer DD
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Sep 03 00:00:00 EDT 2019
Omega-3 Fatty Acids Activate Ciliary FFAR4 to Control Adipogenesis.
Cell
Hilgendorf KI,Johnson CT,Mezger A,Rice SL,Norris AM,Demeter J,Greenleaf WJ,Reiter JF,Kopinke D,Jackson PK
25-0451-82 was used in Flow Cytometry to investigate whether preadipocytes use their cilia to sense and respond to external cues to remodel white adipose tissue.
Wed Nov 27 00:00:00 EST 2019
Isolation and Culture of Microglia.
Current protocols in immunology
Bohlen CJ,Bennett FC,Bennett ML
25-0451 was used in Flow cytometry/Cell sorting to describe approaches for purification of microglia by fluorescence-activated cell sorting using microglia-specific surface markers and for enrichment of microglia by magnetic sorting and immunopanning.
Sat Jun 01 00:00:00 EDT 2019
PDGFRα+ stromal adipocyte progenitors transition into epithelial cells during lobulo-alveologenesis in the murine mammary gland.
Nature communications
Joshi PA,Waterhouse PD,Kasaian K,Fang H,Gulyaeva O,Sul HS,Boutros PC,Khokha R
25-0451 was used in Flow cytometry/Cell sorting to identify the transition of a PDGFRα+ mesenchymal cell population into mammary epithelial progenitors in mice.
Mon Apr 15 00:00:00 EDT 2019
PDGFRα+ stromal adipocyte progenitors transition into epithelial cells during lobulo-alveologenesis in the murine mammary gland.
Nature communications
Joshi PA,Waterhouse PD,Kasaian K,Fang H,Gulyaeva O,Sul HS,Boutros PC,Khokha R
25-0451 was used in Flow cytometry/Cell sorting to identify the transition of a PDGFRα+ mesenchymal cell population into mammary epithelial progenitors in mice.
Mon Apr 15 00:00:00 EDT 2019
Growth Factor Screening in Dystrophic Muscles Reveals PDGFB/PDGFRB-Mediated Migration of Interstitial Stem Cells.
International journal of molecular sciences
Camps J,Grosemans H,Gijsbers R,Maes C,Sampaolesi M
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Mar 05 00:00:00 EST 2019
Microbiota Depletion Impairs Thermogenesis of Brown Adipose Tissue and Browning of White Adipose Tissue.
Cell reports
Li B,Li L,Li M,Lam SM,Wang G,Wu Y,Zhang H,Niu C,Zhang X,Liu X,Hambly C,Jin W,Shui G,Speakman JR
25-0451 was used in Flow cytometry/Cell sorting to indicate that gut microbiota contributes to upregulated thermogenesis in the cold environment and that this may be partially mediated via butyrate.
Tue Mar 05 00:00:00 EST 2019
Bone marrow niche trafficking of miR-126 controls the self-renewal of leukemia stem cells in chronic myelogenous leukemia.
Nature medicine
Zhang B,Nguyen LXT,Li L,Zhao D,Kumar B,Wu H,Lin A,Pellicano F,Hopcroft L,Su YL,Copland M,Holyoake TL,Kuo CJ,Bhatia R,Snyder DS,Ali H,Stein AS,Brewer C,Wang H,McDonald T,Swiderski P,Troadec E,Chen CC,Dorrance A,Pullarkat V,Yuan YC,Perrotti D,Carlesso N,Forman SJ,Kortylewski M,Kuo YH,Marcucci G
25-0451 was used in Flow cytometry/Cell sorting to demonstrate how bone marrow endothelial cells supply miR-126 to leukemia stem cells in chronic myelogenous leukemia which modulates their quiescence and self-renewal.
Tue May 01 00:00:00 EDT 2018
Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor.
Nature
Zacharias WJ,Frank DB,Zepp JA,Morley MP,Alkhaleel FA,Kong J,Zhou S,Cantu E,Morrisey EE
25-0451 was used in Flow cytometry/Cell sorting to identify the AEP lineage as an evolutionarily conserved alveolar progenitor that represents a new target for human lung regeneration strategies.
Thu Mar 08 00:00:00 EST 2018
Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.
Cell
Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Jun 28 00:00:00 EDT 2018
Chanzyme TRPM7 Mediates the Ca2+ Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation.
Immunity
Schappe MS,Szteyn K,Stremska ME,Mendu SK,Downs TK,Seegren PV,Mahoney MA,Dixit S,Krupa JK,Stipes EJ,Rogers JS,Adamson SE,Leitinger N,Desai BN
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Jan 16 00:00:00 EST 2018
E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor.
Immunity
Li Q,Li D,Zhang X,Wan Q,Zhang W,Zheng M,Zou L,Elly C,Lee JH,Liu YC
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Feb 20 00:00:00 EST 2018
Muscle Satellite Cell Cross-Talk with a Vascular Niche Maintains Quiescence via VEGF and Notch Signaling.
Cell stem cell
Verma M,Asakura Y,Murakonda BSR,Pengo T,Latroche C,Chazaud B,McLoon LK,Asakura A
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Oct 04 00:00:00 EDT 2018
A Combination of Ontogeny and CNS Environment Establishes Microglial Identity.
Neuron
Bennett FC,Bennett ML,Yaqoob F,Mulinyawe SB,Grant GA,Hayden Gephart M,Plowey ED,Barres BA
25-0451 was used in Flow cytometry/Cell sorting to disentangle how CNS environment and ontogeny specify microglial identity.
Wed Jun 27 00:00:00 EDT 2018
Defective germline reprogramming rewires the spermatogonial transcriptome.
Nature structural & molecular biology
Vasiliauskaitė L,Berrens RV,Ivanova I,Carrieri C,Reik W,Enright AJ,O'Carroll D
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue May 01 00:00:00 EDT 2018
Bone marrow-derived fibroblasts are a functionally distinct stromal cell population in breast cancer.
The Journal of experimental medicine
Raz Y,Cohen N,Shani O,Bell RE,Novitskiy SV,Abramovitz L,Levy C,Milyavsky M,Leider-Trejo L,Moses HL,Grisaru D,Erez N
25-0451-82 was used in Flow cytometry/Cell sorting to conclude that PDGFRα expression distinguishes two functionally unique CAF populations in breast tumors and metastases and may have important implications for patient stratification and precision therapeutics.
Mon Dec 03 00:00:00 EST 2018
11 Beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis.
Journal of autoimmunity
Hardy RS,Fenton C,Croft AP,Naylor AJ,Begum R,Desanti G,Buckley CD,Lavery G,Cooper MS,Raza K
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed Aug 01 00:00:00 EDT 2018
Inhibition of the JNK/MAPK signaling pathway by myogenesis-associated miRNAs is required for skeletal muscle development.
Cell death and differentiation
Xie SJ,Li JH,Chen HF,Tan YY,Liu SR,Zhang Y,Xu H,Yang JH,Liu S,Zheng LL,Huang MB,Guo YH,Zhang Q,Zhou H,Qu LH
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2018
VISTA expression by microglia decreases during inflammation and is differentially regulated in CNS diseases.
Glia
Borggrewe M,Grit C,Den Dunnen WFA,Burm SM,Bajramovic JJ,Noelle RJ,Eggen BJL,Laman JD
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Sat Dec 01 00:00:00 EST 2018
A dual genetic tracing system identifies diverse and dynamic origins of cardiac valve mesenchyme.
Development (Cambridge, England)
Liu K,Yu W,Tang M,Tang J,Liu X,Liu Q,Li Y,He L,Zhang L,Evans SM,Tian X,Lui KO,Zhou B
25-0451 was used in Flow cytometry to provide a proof-of-principle application of the Nigri-nox system for in vivo mouse genomic engineering.
Mon Sep 17 00:00:00 EDT 2018
Protease-activated receptor-2 signaling through β-arrestin-2 mediates Alternaria alkaline serine protease-induced airway inflammation.
American journal of physiology. Lung cellular and molecular physiology
Yee MC,Nichols HL,Polley D,Saifeddine M,Pal K,Lee K,Wilson EH,Daines MO,Hollenberg MD,Boitano S,DeFea KA
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Sat Dec 01 00:00:00 EST 2018
MyD88 is required for satellite cell-mediated myofiber regeneration in dystrophin-deficient mdx mice.
Human molecular genetics
Gallot YS,Straughn AR,Bohnert KR,Xiong G,Hindi SM,Kumar A
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2018
Simultaneous isolation of mesenchymal stem cells and endothelial progenitor cells derived from murine bone marrow.
Experimental and therapeutic medicine
Wang X,Zhao Z,Zhang H,Hou J,Feng W,Zhang M,Guo J,Xia J,Ge Q,Chen X,Wu X
25-0451 was used in Flow cytometry/Cell sorting to develop a method for the simultaneous isolation of homogenous populations of mesenchymal stem or stromal cells and endothelial progenitor cells from murine bone marrow.
Sat Dec 01 00:00:00 EST 2018
mTOR Modulates CD8+ T Cell Differentiation in Mice with Invasive Pulmonary Aspergillosis.
Open life sciences
Wang H,Xiao Y,Su L,Cui N,Liu D
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Jan 01 00:00:00 EST 2018
MT4-MMP deficiency increases patrolling monocyte recruitment to early lesions and accelerates atherosclerosis.
Nature communications
Clemente C,Rius C,Alonso-Herranz L,Martín-Alonso M,Pollán Á,Camafeita E,Martínez F,Mota RA,Núñez V,Rodríguez C,Seiki M,Martínez-González J,Andrés V,Ricote M,Arroyo AG
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Mar 02 00:00:00 EST 2018
Small-RNA sequencing identifies dynamic microRNA deregulation during skeletal muscle lineage progression.
Scientific reports
Castel D,Baghdadi MB,Mella S,Gayraud-Morel B,Marty V,Cavaillé J,Antoniewski C,Tajbakhsh S
25-0451 was used in Flow cytometry/Cell sorting to uncover a key resource for functional analyses of miRNAs in skeletal myogenesis and in the regulation of stem cell self-renewal and tissue homeostasis.
Fri Mar 09 00:00:00 EST 2018
Lsd1 regulates skeletal muscle regeneration and directs the fate of satellite cells.
Nature communications
Tosic M,Allen A,Willmann D,Lepper C,Kim J,Duteil D,Schüle R
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Jan 25 00:00:00 EST 2018
AMPK Activation Regulates LTBP4-Dependent TGF-β1 Secretion by Pro-inflammatory Macrophages and Controls Fibrosis in Duchenne Muscular Dystrophy.
Cell reports
Juban G,Saclier M,Yacoub-Youssef H,Kernou A,Arnold L,Boisson C,Ben Larbi S,Magnan M,Cuvellier S,Théret M,Petrof BJ,Desguerre I,Gondin J,Mounier R,Chazaud B
25-0451 was used in Flow cytometry/Cell sorting to conclude that an AMPK-LTBP4 axis in inflammatory macrophages controls the production of TGF-β1, which is further activated by and acts on fibroblastic cells, leading to fibrosis in DMD.
Tue Nov 20 00:00:00 EST 2018
Diet-Induced Obesity Elicits Macrophage Infiltration and Reduction in Spine Density in the Hypothalami of Male but Not Female Mice.
Frontiers in immunology
Lainez NM,Jonak CR,Nair MG,Ethell IM,Wilson EH,Carson MJ,Coss D
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed Sep 25 00:00:00 EDT 2019
Allograft dendritic cell p40 homodimers activate donor-reactive memory CD8+ T cells.
JCI insight
Tsuda H,Su CA,Tanaka T,Ayasoufi K,Min B,Valujskikh A,Fairchild RL
25-0451 was used in Flow cytometry/Cell sorting to study the mechanisms enhancing endogenous memory T cell activation to mediate tissue injury within the increased inflammatory environment of allografts subjected to prolonged cold ischaemic storage.
Thu Feb 22 00:00:00 EST 2018
Adipocyte hypertrophy and lipid dynamics underlie mammary gland remodeling after lactation.
Nature communications
Zwick RK,Rudolph MC,Shook BA,Holtrup B,Roth E,Lei V,Van Keymeulen A,Seewaldt V,Kwei S,Wysolmerski J,Rodeheffer MS,Horsley V
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Sep 04 00:00:00 EDT 2018
ATF3 Sustains IL-22-Induced STAT3 Phosphorylation to Maintain Mucosal Immunity Through Inhibiting Phosphatases.
Frontiers in immunology
Glal D,Sudhakar JN,Lu HH,Liu MC,Chiang HY,Liu YC,Cheng CF,Shui JW
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Sep 26 00:00:00 EDT 2019
NF1 heterozygosity fosters de novo tumorigenesis but impairs malignant transformation.
Nature communications
Brosseau JP,Liao CP,Wang Y,Ramani V,Vandergriff T,Lee M,Patel A,Ariizumi K,Le LQ
25-0451 was used in Flow cytometry/Cell sorting to study the role of the neurofibromatosis type 1 tumour suppressor gene in de novo tumorigenesis and malignant transformation.
Tue Nov 27 00:00:00 EST 2018
Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow.
Nature communications
Xu C,Gao X,Wei Q,Nakahara F,Zimmerman SE,Mar J,Frenette PS
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Jun 22 00:00:00 EDT 2018
β Cell-Specific Deletion of the IL-1 Receptor Antagonist Impairs β Cell Proliferation and Insulin Secretion.
Cell reports
Böni-Schnetzler M,Häuselmann SP,Dalmas E,Meier DT,Thienel C,Traub S,Schulze F,Steiger L,Dror E,Martin P,Herrera PL,Gabay C,Donath MY
25-0451 was used in Flow cytometry/Cell sorting to investigate the protective role of local Interleukin-1 receptor antagonist in pancreatic islet Β cell-specific versus myeloid-cell-specific IL-1Ra knockout mice.
Tue Feb 13 00:00:00 EST 2018
Mesenchymal stromal cells-derived matrix Gla protein contribute to the alleviation of experimental colitis.
Cell death & disease
Feng Y,Liao Y,Huang W,Lai X,Luo J,Du C,Lin J,Zhang Z,Qiu D,Liu Q,Shen H,Xiang AP,Zhang Q
25-0451 was used in Flow cytometry/Cell sorting to study the role of matrix Gla protein as a novel mediator of mesenchymal stromal cell-mediated immunomodulation in treating Crohn's disease.
Thu Jun 07 00:00:00 EDT 2018
Estriol Reduces Pulmonary Immune Cell Recruitment and Inflammation to Protect Female Mice From Severe Influenza.
Endocrinology
Vermillion MS,Ursin RL,Attreed SE,Klein SL
25-0451-82 was used in Flow cytometry/Cell sorting to suggest that exogenous E3 confers protection during IAV infection through immunomodulatory mechanisms and that E3 may have broad therapeutic potential in the context of both infectious and noninfectious inflammatory diseases.
Sat Sep 01 00:00:00 EDT 2018
Rap1 deficiency-provoked paracrine dysfunction impairs immunosuppressive potency of mesenchymal stem cells in allograft rejection of heart transplantation.
Cell death & disease
Ding Y,Liang X,Zhang Y,Yi L,Shum HC,Chen Q,Chan BP,Fan H,Liu Z,Tergaonkar V,Qi Z,Tse HF,Lian Q
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed Mar 07 00:00:00 EST 2018
Partial depletion of CD206-positive M2-like macrophages induces proliferation of beige progenitors and enhances browning after cold stimulation.
Scientific reports
Igarashi Y,Nawaz A,Kado T,Bilal M,Kuwano T,Yamamoto S,Sasahara M,Jiuxiang X,Inujima A,Koizumi K,Imura J,Shibahara N,Usui I,Fujisaka S,Tobe K
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2018
FGF-dependent metabolic control of vascular development.
Nature
Yu P,Wilhelm K,Dubrac A,Tung JK,Alves TC,Fang JS,Xie Y,Zhu J,Chen Z,De Smet F,Zhang J,Jin SW,Sun L,Sun H,Kibbey RG,Hirschi KK,Hay N,Carmeliet P,Chittenden TW,Eichmann A,Potente M,Simons M
25-0451 was used in Flow cytometry/Cell sorting to identify FGF receptor signalling as a critical regulator of vascular development.
Thu May 11 00:00:00 EDT 2017
Neurotoxic reactive astrocytes are induced by activated microglia.
Nature
Liddelow SA,Guttenplan KA,Clarke LE,Bennett FC,Bohlen CJ,Schirmer L,Bennett ML,Münch AE,Chung WS,Peterson TC,Wilton DK,Frouin A,Napier BA,Panicker N,Kumar M,Buckwalter MS,Rowitch DH,Dawson VL,Dawson TM,Stevens B,Barres BA
25-0451 was used in Flow cytometry/Cell sorting to elucidate how neurotoxic, reactive astrocytes are induced by classically activated neuroinflammatory microglia.
Thu Jan 26 00:00:00 EST 2017
Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer.
Nature
Lim JS,Ibaseta A,Fischer MM,Cancilla B,O'Young G,Cristea S,Luca VC,Yang D,Jahchan NS,Hamard C,Antoine M,Wislez M,Kong C,Cain J,Liu YW,Kapoun AM,Garcia KC,Hoey T,Murriel CL,Sage J
25-0451 was used in Flow cytometry/Cell sorting to show that Notch signalling can be both tumour suppressive and pro-tumorigenic in small-cell lung cancer.
Thu May 18 00:00:00 EDT 2017
Adipose Tissue Macrophage-Derived Exosomal miRNAs Can Modulate In Vivo and In Vitro Insulin Sensitivity.
Cell
Ying W,Riopel M,Bandyopadhyay G,Dong Y,Birmingham A,Seo JB,Ofrecio JM,Wollam J,Hernandez-Carretero A,Fu W,Li P,Olefsky JM
25-0451 was used in Flow cytometry/Cell sorting to study the secretion of exosomes containing miRNA cargo by adipose tissue macrophages.
Thu Oct 05 00:00:00 EDT 2017
Interleukin-33-Activated Islet-Resident Innate Lymphoid Cells Promote Insulin Secretion through Myeloid Cell Retinoic Acid Production.
Immunity
Dalmas E,Lehmann FM,Dror E,Wueest S,Thienel C,Borsigova M,Stawiski M,Traunecker E,Lucchini FC,Dapito DH,Kallert SM,Guigas B,Pattou F,Kerr-Conte J,Maechler P,Girard JP,Konrad D,Wolfrum C,Böni-Schnetzler M,Finke D,Donath MY
25-0451 was used in Flow cytometry/Cell sorting to provide evidence that an immunometabolic crosstalk between islet-derived IL-33, ILC2s, and myeloid cells fosters insulin secretion.
Tue Nov 21 00:00:00 EST 2017
Differential cytokine contributions of perivascular haematopoietic stem cell niches.
Nature cell biology
Asada N,Kunisaki Y,Pierce H,Wang Z,Fernandez NF,Birbrair A,Ma'ayan A,Frenette PS
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
T-Cell Mineralocorticoid Receptor Controls Blood Pressure by Regulating Interferon-Gamma.
Circulation research
Sun XN,Li C,Liu Y,Du LJ,Zeng MR,Zheng XJ,Zhang WC,Liu Y,Zhu M,Kong D,Zhou L,Lu L,Shen ZX,Yi Y,Du L,Qin M,Liu X,Hua Z,Sun S,Yin H,Zhou B,Yu Y,Zhang Z,Duan SZ
25-0451 was used in Flow cytometry/Cell sorting to determine the role of T-cell mineralocorticoid receptor in blood pressure regulation and explore the mechanism.
Fri May 12 00:00:00 EDT 2017
A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.
The Journal of clinical investigation
Berlato C,Khan MN,Schioppa T,Thompson R,Maniati E,Montfort A,Jangani M,Canosa M,Kulbe H,Hagemann UB,Duncan AR,Fletcher L,Wilkinson RW,Powles T,Quezada SA,Balkwill FR
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Stromal cell cadherin-11 regulates adipose tissue inflammation and diabetes.
The Journal of clinical investigation
Chang SK,Kohlgruber AC,Mizoguchi F,Michelet X,Wolf BJ,Wei K,Lee PY,Lynch L,Duquette D,Ceperuelo-Mallafré V,Banks AS,Brenner MB
25-0451 was used in Flow cytometry/Cell sorting to suggest that stromal fibroblasts expressing cadherin-11 regulate adipose tissue inflammation.
Fri Sep 01 00:00:00 EDT 2017
Diverse Requirements for Microglial Survival, Specification, and Function Revealed by Defined-Medium Cultures.
Neuron
Bohlen CJ,Bennett FC,Tucker AF,Collins HY,Mulinyawe SB,Barres BA
25-0451 was used in Flow cytometry/Cell sorting to indicate that the specialized gene expression profile of mature microglia requires continuous instructive signaling from the intact CNS.
Wed May 17 00:00:00 EDT 2017
Oncolytic Adenovirus and Tumor-Targeting Immune Modulatory Therapy Improve Autologous Cancer Vaccination.
Cancer research
Jiang H,Rivera-Molina Y,Gomez-Manzano C,Clise-Dwyer K,Bover L,Vence LM,Yuan Y,Lang FF,Toniatti C,Hossain MB,Fueyo J
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Sat Jul 15 00:00:00 EDT 2017
Sigma-1 receptors control immune-driven peripheral opioid analgesia during inflammation in mice.
Proceedings of the National Academy of Sciences of the United States of America
Tejada MA,Montilla-García A,Cronin SJ,Cikes D,Sánchez-Fernández C,González-Cano R,Ruiz-Cantero MC,Penninger JM,Vela JM,Baeyens JM,Cobos EJ
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Aug 01 00:00:00 EDT 2017
Induction of Broad-Spectrum Protective Immunity against Disparate Cryptococcus Serotypes.
Frontiers in immunology
Van Dyke MCC,Chaturvedi AK,Hardison SE,Leopold Wager CM,Castro-Lopez N,Hole CR,Wozniak KL,Wormley FL
25-0451 was used in Flow cytometry/Cell sorting to provide "proof-of-concept" for the development of a cryptococcal vaccine that provides cross-protection against multiple disparate serotypes of Cryptococcus.
Wed Nov 20 00:00:00 EST 2019
Obesity reversibly depletes the basal cell population and enhances mammary epithelial cell estrogen receptor alpha expression and progenitor activity.
Breast cancer research : BCR
Chamberlin T,D'Amato JV,Arendt LM
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed Nov 29 00:00:00 EST 2017
Depletion of microglia exacerbates postischemic inflammation and brain injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Jin WN,Shi SX,Li Z,Li M,Wood K,Gonzales RJ,Liu Q
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2017
An atypical role for the myeloid receptor Mincle in central nervous system injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Arumugam TV,Manzanero S,Furtado M,Biggins PJ,Hsieh YH,Gelderblom M,MacDonald KP,Salimova E,Li YI,Korn O,Dewar D,Macrae IM,Ashman RB,Tang SC,Rosenthal NA,Ruitenberg MJ,Magnus T,Wells CA
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2017
The effects of C5aR1 on leukocyte infiltration following pilocarpine-induced status epilepticus.
Epilepsia
Benson MJ,Manzanero S,Borges K
25-0451 was used in Flow cytometry/Cell sorting to show that C5aR1 is an inflammatory mediator and may play a role in epileptogenesis.
Sat Apr 01 00:00:00 EDT 2017
Role of Triggering Receptor Expressed on Myeloid Cell-1 Expression in Mammalian Target of Rapamycin Modulation of CD8+ T-cell Differentiation during the Immune Response to Invasive Pulmonary Aspergillosis.
Chinese medical journal
Cui N,Wang H,Su LX,Zhang JH,Long Y,Liu DW
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Sat May 20 00:00:00 EDT 2017
Cornea lymphatics drive the CD8+ T-cell response to herpes simplex virus-1.
Immunology and cell biology
Gurung HR,Carr MM,Carr DJ
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2017
Diet-Derived Short Chain Fatty Acids Stimulate Intestinal Epithelial Cells To Induce Mucosal Tolerogenic Dendritic Cells.
Journal of immunology (Baltimore, Md. : 1950)
Goverse G,Molenaar R,Macia L,Tan J,Erkelens MN,Konijn T,Knippenberg M,Cook EC,Hanekamp D,Veldhoen M,Hartog A,Roeselers G,Mackay CR,Mebius RE
25-0451 was used in Flow cytometry/Cell sorting to study the effect of dietary fiber and short chain fatty acids on the vitamin A converting enzyme RALDH1 in intestinal epithelial cells.
Wed Mar 01 00:00:00 EST 2017
Cytochrome P450 26A1 modulates natural killer cells in mouse early pregnancy.
Journal of cellular and molecular medicine
Meng CY,Li ZY,Fang WN,Song ZH,Yang DD,Li DD,Yang Y,Peng JP
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
β3-Adrenergic Regulation of EPC Features Through Manipulation of the Bone Marrow MSC Niche.
Journal of cellular biochemistry
Vafaei R,Nassiri SM,Siavashi V
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Dec 01 00:00:00 EST 2017
The common parasite Toxoplasma gondii induces prostatic inflammation and microglandular hyperplasia in a mouse model.
The Prostate
Colinot DL,Garbuz T,Bosland MC,Wang L,Rice SE,Sullivan WJ,Arrizabalaga G,Jerde TJ
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Sat Jul 01 00:00:00 EDT 2017
Gli1 identifies osteogenic progenitors for bone formation and fracture repair.
Nature communications
Shi Y,He G,Lee WC,McKenzie JA,Silva MJ,Long F
25-0451 was used in Flow cytometry/Cell sorting to study how Gli1 marks mesenchymal progenitors responsible for both normal bone formation and fracture repair.
Mon Dec 11 00:00:00 EST 2017
CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors.
Nature communications
Nawaz A,Aminuddin A,Kado T,Takikawa A,Yamamoto S,Tsuneyama K,Igarashi Y,Ikutani M,Nishida Y,Nagai Y,Takatsu K,Imura J,Sasahara M,Okazaki Y,Ueki K,Okamura T,Tokuyama K,Ando A,Matsumoto M,Mori H,Nakagawa T,Kobayashi N,Saeki K,Usui I,Fujisaka S,Tobe K
25-0451 was used in Flow cytometry/Cell sorting to report that M2-like macrophages, create a microenvironment that inhibits proliferation of adipocyte progenitors due to the secretion of TGF-β1.
Fri Aug 18 00:00:00 EDT 2017
The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration.
eLife
Xiong G,Hindi SM,Mann AK,Gallot YS,Bohnert KR,Cavener DR,Whittemore SR,Kumar A
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Mar 23 00:00:00 EDT 2017
LYG1 exerts antitumor function through promoting the activation, proliferation, and function of CD4+ T cells.
Oncoimmunology
Liu H,Zhang Y,Liu Z,Wang P,Mo X,Fu W,Liu W,Cheng Y,Han W
25-0451 was used in Flow cytometry/Cell sorting to reveal a tumor-inhibiting role for LYG1 through promoting the activation, proliferation, and function of CD4+T cells in antitumor immune responses, offering implications for novel tumor immunotherapy.
Tue Jan 12 00:00:00 EST 2021
Interleukin-21 combined with PD-1 or CTLA-4 blockade enhances antitumor immunity in mouse tumor models.
Oncoimmunology
Lewis KE,Selby MJ,Masters G,Valle J,Dito G,Curtis WR,Garcia R,Mink KA,Waggie KS,Holdren MS,Grosso JF,Korman AJ,Jure-Kunkel M,Dillon SR
25-0451 was used in Flow cytometry/Cell sorting to investigate the efficacy of immune-modulatory interleukin-21 combined with checkpoint blockade in several syngeneic mouse tumor models.
Tue Jan 12 00:00:00 EST 2021
Brown adipocytes can display a mammary basal myoepithelial cell phenotype in vivo.
Molecular metabolism
Li L,Li B,Li M,Niu C,Wang G,Li T,Król E,Jin W,Speakman JR
25-0451 was used in Flow cytometry/Cell sorting to provide a novel perspective on the interrelationships between adipocytes and mammary cells with implications for our understanding of obesity and breast cancer.
Sun Oct 01 00:00:00 EDT 2017
microRNA-449a modulates medullary thymic epithelial cell differentiation.
Scientific reports
Chen P,Zhang H,Sun X,Hu Y,Jiang W,Liu Z,Liu S,Zhang X
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Nov 21 00:00:00 EST 2017
Tristetraprolin expression by keratinocytes controls local and systemic inflammation.
JCI insight
Andrianne M,Assabban A,La C,Mogilenko D,Salle DS,Fleury S,Doumont G,Van Simaeys G,Nedospasov SA,Blackshear PJ,Dombrowicz D,Goriely S,Van Maele L
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Jun 02 00:00:00 EDT 2017
Control of metastatic niche formation by targeting APBA3/Mint3 in inflammatory monocytes.
Proceedings of the National Academy of Sciences of the United States of America
Hara T,Nakaoka HJ,Hayashi T,Mimura K,Hoshino D,Inoue M,Nagamura F,Murakami Y,Seiki M,Sakamoto T
25-0451-82 was used in Flow cytometry/Cell sorting to report that APBA3-deficient mice show reduced metastasis, with no apparent effect on primary tumor growth.
Tue May 30 00:00:00 EDT 2017
The Interleukin (IL)-1R1 pathway is a critical negative regulator of PyMT-mediated mammary tumorigenesis and pulmonary metastasis.
Oncoimmunology
Dagenais M,Dupaul-Chicoine J,Douglas T,Champagne C,Morizot A,Saleh M
25-0451 was used in Flow cytometry/Cell sorting to genetically investigate the role of the interleukin-1 receptor 1 pathway in breast cancer tumourigenesis and metastasis using a mouse model.
Tue Jan 12 00:00:00 EST 2021
Zoledronate suppressed angiogenesis and osteogenesis by inhibiting osteoclasts formation and secretion of PDGF-BB.
PloS one
Gao SY,Zheng GS,Wang L,Liang YJ,Zhang SE,Lao XM,Li K,Liao GQ
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Sep 18 00:00:00 EDT 2017
Irgm1 coordinately regulates autoimmunity and host defense at select mucosal surfaces.
JCI insight
Azzam KM,Madenspacher JH,Cain DW,Lai L,Gowdy KM,Rai P,Janardhan K,Clayton N,Cunningham W,Jensen H,Patel PS,Kearney JF,Taylor GA,Fessler MB
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Aug 17 00:00:00 EDT 2017
Cardiosphere-Derived Cells Require Endoglin for Paracrine-Mediated Angiogenesis.
Stem cell reports
Redgrave RE,Tual-Chalot S,Davison BJ,Singh E,Hall D,Amirrasouli MM,Gilchrist D,Medvinsky A,Arthur HM
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue May 09 00:00:00 EDT 2017
Classical dendritic cells are required for dietary antigen-mediated induction of peripheral T(reg) cells and tolerance.
Nature immunology
Esterházy D,Loschko J,London M,Jove V,Oliveira TY,Mucida D
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Sun May 01 00:00:00 EDT 2016
Oligodendrocyte death results in immune-mediated CNS demyelination.
Nature neuroscience
Traka M,Podojil JR,McCarthy DP,Miller SD,Popko B
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
The breast tumor microenvironment alters the phenotype and function of natural killer cells.
Cellular & molecular immunology
Krneta T,Gillgrass A,Chew M,Ashkar AA
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
Probing chromatin landscape reveals roles of endocardial TBX20 in septation.
The Journal of clinical investigation
Boogerd CJ,Aneas I,Sakabe N,Dirschinger RJ,Cheng QJ,Zhou B,Chen J,Nobrega MA,Evans SM
25045182 was used in flow cytometry to clarify the role of endocardial TBX20 in heart development
Mon Aug 01 00:00:00 EDT 2016
Alloantigen-specific regulatory T cells generated with a chimeric antigen receptor.
The Journal of clinical investigation
MacDonald KG,Hoeppli RE,Huang Q,Gillies J,Luciani DS,Orban PC,Broady R,Levings MK
25-0451 was used in Flow cytometry/Cell sorting to investigate alloantigen-specific regulatory T cells generated with a chimeric antigen receptor.
Fri Apr 01 00:00:00 EDT 2016
Non-Cell-Autonomous Regulation of Prostate Epithelial Homeostasis by Androgen Receptor.
Molecular cell
Zhang B,Kwon OJ,Henry G,Malewska A,Wei X,Zhang L,Brinkley W,Zhang Y,Castro PD,Titus M,Chen R,Sayeeduddin M,Raj GV,Mauck R,Roehrborn C,Creighton CJ,Strand DW,Ittmann MM,Xin L
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Sep 15 00:00:00 EDT 2016
G-CSF is a key modulator of MDSC and could be a potential therapeutic target in colitis-associated colorectal cancers.
Protein & cell
Li W,Zhang X,Chen Y,Xie Y,Liu J,Feng Q,Wang Y,Yuan W,Ma J
25-0451 was used in Flow cytometry/Cell sorting to indicate that G-CSF is a critical regulating molecule in the migration, proliferation and functional maintenance of myeloid derived suppressor cells.
Mon Feb 01 00:00:00 EST 2016
HDAC Inhibitors Enhance T-Cell Chemokine Expression and Augment Response to PD-1 Immunotherapy in Lung Adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research
Zheng H,Zhao W,Yan C,Watson CC,Massengill M,Xie M,Massengill C,Noyes DR,Martinez GV,Afzal R,Chen Z,Ren X,Antonia SJ,Haura EB,Ruffell B,Beg AA
25-0451 was used in Flow cytometry/Cell sorting to test whether strategies that increase T-cell infiltration to tumours can be efficacious in enhancing immunotherapy response.
Mon Aug 15 00:00:00 EDT 2016
Lymphatic Contribution to the Cellular Niche in Heterotopic Ossification.
Annals of surgery
Loder S,Agarwal S,Sorkin M,Breuler C,Li J,Peterson J,Gardenier J,Hsieh HH,Wang SC,Mehrara BJ,Levi B
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2016
New tools for studying microglia in the mouse and human CNS.
Proceedings of the National Academy of Sciences of the United States of America
Bennett ML,Bennett FC,Liddelow SA,Ajami B,Zamanian JL,Fernhoff NB,Mulinyawe SB,Bohlen CJ,Adil A,Tucker A,Weissman IL,Chang EF,Li G,Grant GA,Hayden Gephart MG,Barres BA
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Mar 22 00:00:00 EDT 2016
CNS accumulation of regulatory B cells is VLA-4-dependent.
Neurology(R) neuroimmunology & neuroinflammation
Lehmann-Horn K,Sagan SA,Winger RC,Spencer CM,Bernard CC,Sobel RA,Zamvil SS
25-0451 was used in Immunocytochemistry to demonstrate that accumulation of Breg in the CNS is dependent on VLA-4.
Fri Apr 01 00:00:00 EDT 2016
Analysis of Bone-Cartilage-Stromal Progenitor Populations in Trauma Induced and Genetic Models of Heterotopic Ossification.
Stem cells (Dayton, Ohio)
Agarwal S,Loder SJ,Sorkin M,Li S,Shrestha S,Zhao B,Mishina Y,James AW,Levi B
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed Jun 01 00:00:00 EDT 2016
Caspase-12, but Not Caspase-11, Inhibits Obesity and Insulin Resistance.
Journal of immunology (Baltimore, Md. : 1950)
Skeldon AM,Morizot A,Douglas T,Santoro N,Kursawe R,Kozlitina J,Caprio S,Mehal WZ,Saleh M
25-0451 was used in Flow cytometry/Cell sorting to investigate a role for caspase-11 and caspase-12 in obesity and insulin resistance.
Fri Jan 01 00:00:00 EST 2016
Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency.
Journal of immunology (Baltimore, Md. : 1950)
Menendez CM,Jinkins JK,Carr DJ
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Aug 15 00:00:00 EDT 2016
ECM-Dependence of Endothelial Progenitor Cell Features.
Journal of cellular biochemistry
Siavashi V,Nassiri SM,Rahbarghazi R,Vafaei R,Sariri R
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Effects of nerve growth factor and basic fibroblast growth factor dual gene modification on rat bone marrow mesenchymal stem cell differentiation into neuron-like cells in vitro.
Molecular medicine reports
Hu Y,Zhang Y,Tian K,Xun C,Wang S,Lv D
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
A flow cytometric approach to analyzing mature and progenitor endothelial cells following traumatic brain injury.
Journal of neuroscience methods
Assis-Nascimento P,Umland O,Cepero ML,Liebl DJ
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Apr 01 00:00:00 EDT 2016
Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency.
Stem cell reports
Mucci A,Kunkiel J,Suzuki T,Brennig S,Glage S,Kühnel MP,Ackermann M,Happle C,Kuhn A,Schambach A,Trapnell BC,Hansen G,Moritz T,Lachmann N
25-0451 was used in Flow cytometry/Cell sorting to describe a protocol to obtain mature and functional MΦ from healthy as well as disease-specific murine iPSCs.
Tue Aug 09 00:00:00 EDT 2016
A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis.
Nature communications
Jeric I,Maurer G,Cavallo AL,Raguz J,Desideri E,Tarkowski B,Parrini M,Fischer I,Zatloukal K,Baccarini M
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed Dec 21 00:00:00 EST 2016
Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis.
Nature communications
Ruhland MK,Loza AJ,Capietto AH,Luo X,Knolhoff BL,Flanagan KC,Belt BA,Alspach E,Leahy K,Luo J,Schaffer A,Edwards JR,Longmore G,Faccio R,DeNardo DG,Stewart SA
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed Jun 08 00:00:00 EDT 2016
Characterization of Cells Isolated from Genetic and Trauma-Induced Heterotopic Ossification.
PloS one
Agarwal S,Drake J,Qureshi AT,Loder S,Li S,Shigemori K,Peterson J,Cholok D,Forsberg JA,Mishina Y,Davis TA,Levi B
25-0451 was used in Flow cytometry/Cell sorting to demonstrate that across models, cells derived from tissues forming heterotopic ossification exhibit increased osteogenic differentiation compared to normal tissues or osteoblasts.
Wed Aug 23 00:00:00 EDT 2017
Severe Changes in Thymic Microenvironment in a Chronic Experimental Model of Paracoccidioidomycosis.
PloS one
Alves da Costa T,Di Gangi R,Thomé R,Barreto Felisbino M,Pires Bonfanti A,Lumi Watanabe Ishikawa L,Sartori A,Burger E,Verinaud L
25-0451 was used in Flow cytometry/Cell sorting to develop a new experimental model where Pb yeast cells are injected through the intraperitoneal route and mice are evaluated over 120 days of infection.
Mon May 22 00:00:00 EDT 2017
Targeting VEGF-A in myeloid cells enhances natural killer cell responses to chemotherapy and ameliorates cachexia.
Nature communications
Klose R,Krzywinska E,Castells M,Gotthardt D,Putz EM,Kantari-Mimoun C,Chikdene N,Meinecke AK,Schrödter K,Helfrich I,Fandrey J,Sexl V,Stockmann C
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Aug 19 00:00:00 EDT 2016
Protein Kinase D2 Protects against Acute Colitis Induced by Dextran Sulfate Sodium in Mice.
Scientific reports
Xiong J,Zhou MF,Wang YD,Chen LP,Xu WF,Wang YD,Deng F,Liu SD
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Sep 23 00:00:00 EDT 2016
MicroRNA regulation of endothelial TREX1 reprograms the tumour microenvironment.
Nature communications
Wilson R,Espinosa-Diez C,Kanner N,Chatterjee N,Ruhl R,Hipfinger C,Advani SJ,Li J,Khan OF,Franovic A,Weis SM,Kumar S,Coussens LM,Anderson DG,Chen CC,Cheresh DA,Anand S
25-0451 was used in Flow cytometry/Cell sorting to demonstrate a unique mechanism by which ectopic microRNA-103 can manipulate tumour-associated endothelial cells to enhance tumour cell death.
Fri Nov 25 00:00:00 EST 2016
Preparation of Single Cell Suspensions from Mouse Aorta.
Bio-protocol
Hu D,Yin C,Mohanta SK,Weber C,Habenicht AJ
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Sun Jun 05 00:00:00 EDT 2016
Irradiation of necrotic cancer cells, employed for pulsing dendritic cells (DCs), potentiates DC vaccine-induced antitumor immunity against high-grade glioma.
Oncoimmunology
Vandenberk L,Garg AD,Verschuere T,Koks C,Belmans J,Beullens M,Agostinis P,De Vleeschouwer S,Van Gool SW
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2016
The Lymphatic Endothelial mCLCA1 Antibody Induces Proliferation and Growth of Lymph Node Lymphatic Sinuses.
PloS one
Jordan-Williams KL,Ramanujam N,Farr AG,Ruddell A
25-0451 was used in Flow cytometry/Cell sorting to investigate the induction of proliferation and growth of lymph node lymphatic sinuses.
Mon Jul 10 00:00:00 EDT 2017
Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine.
Scientific reports
Ochi T,Feng Y,Kitamoto S,Nagao-Kitamoto H,Kuffa P,Atarashi K,Honda K,Teitelbaum DH,Kamada N
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed Jun 15 00:00:00 EDT 2016
LTβR controls thymic portal endothelial cells for haematopoietic progenitor cell homing and T-cell regeneration.
Nature communications
Shi Y,Wu W,Chai Q,Li Q,Hou Y,Xia H,Ren B,Xu H,Guo X,Jin C,Lv M,Wang Z,Fu YX,Zhu M
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Aug 05 00:00:00 EDT 2016
High salt primes a specific activation state of macrophages, M(Na).
Cell research
Zhang WC,Zheng XJ,Du LJ,Sun JY,Shen ZX,Shi C,Sun S,Zhang Z,Chen XQ,Qin M,Liu X,Tao J,Jia L,Fan HY,Zhou B,Yu Y,Ying H,Hui L,Liu X,Yi X,Liu X,Zhang L,Duan SZ
25-0451 was used in Flow cytometry/Cell sorting to investigate the mechanisms of high salt in disease risk, showing that it primes a specific activation state of macrophages.
Sat Aug 01 00:00:00 EDT 2015
Host microbiota constantly control maturation and function of microglia in the CNS.
Nature neuroscience
Erny D,Hrabě de Angelis AL,Jaitin D,Wieghofer P,Staszewski O,David E,Keren-Shaul H,Mahlakoiv T,Jakobshagen K,Buch T,Schwierzeck V,Utermöhlen O,Chun E,Garrett WS,McCoy KD,Diefenbach A,Staeheli P,Stecher B,Amit I,Prinz M
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2015
Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cells.
The Journal of clinical investigation
Gori JL,Butler JM,Chan YY,Chandrasekaran D,Poulos MG,Ginsberg M,Nolan DJ,Elemento O,Wood BL,Adair JE,Rafii S,Kiem HP
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2015
Resolvin E1 inhibits dendritic cell migration in the skin and attenuates contact hypersensitivity responses.
The Journal of experimental medicine
Sawada Y,Honda T,Hanakawa S,Nakamizo S,Murata T,Ueharaguchi-Tanada Y,Ono S,Amano W,Nakajima S,Egawa G,Tanizaki H,Otsuka A,Kitoh A,Dainichi T,Ogawa N,Kobayashi Y,Yokomizo T,Arita M,Nakamura M,Miyachi Y,Kabashima K
25-0451 was used in Flow cytometry/Cell sorting to study the inhibition of dendritic cell migration in the skin and the attenuation of contact hypersensitivity responses via Resolvin E1.
Mon Oct 19 00:00:00 EDT 2015
Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus.
EMBO molecular medicine
Herbst S,Shah A,Mazon Moya M,Marzola V,Jensen B,Reed A,Birrell MA,Saijo S,Mostowy S,Shaunak S,Armstrong-James D
25-0451 was used in Flow cytometry/Cell sorting to study how the inhibition of the TLR9-BTK-calcineurin-NFAT signalling pathway is a key immune defect that can lead to organ transplant-related aspergillosis.
Sun Mar 01 00:00:00 EST 2015
Tracking and Functional Characterization of Epithelial-Mesenchymal Transition and Mesenchymal Tumor Cells during Prostate Cancer Metastasis.
Cancer research
Ruscetti M,Quach B,Dadashian EL,Mulholland DJ,Wu H
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2015
Atypical chemokine receptor 1 deficiency reduces atherogenesis in ApoE-knockout mice.
Cardiovascular research
Wan W,Liu Q,Lionakis MS,Marino AP,Anderson SA,Swamydas M,Murphy PM
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2015
Complex alterations in microglial M1/M2 markers during the development of epilepsy in two mouse models.
Epilepsia
Benson MJ,Manzanero S,Borges K
25-0451 was used in Flow cytometry/Cell sorting to demonstrate that the microglial inflammatory response during epileptogenesis is complex, varies between models, and appears to correlate with chronic seizure frequency.
Mon Jun 01 00:00:00 EDT 2015
Myogenic-specific ablation of Fgfr1 impairs FGF2-mediated proliferation of satellite cells at the myofiber niche but does not abolish the capacity for muscle regeneration.
Frontiers in aging neuroscience
Yablonka-Reuveni Z,Danoviz ME,Phelps M,Stuelsatz P
25-0451 was used in Flow cytometry/Cell sorting to investigate FGFR gene expression in quiescent SCs and their proliferating progeny, and its role in myogenesis.
Mon Jun 15 00:00:00 EDT 2015
Epidermal keratinocytes initiate wound healing and pro-inflammatory immune responses following percutaneous schistosome infection.
International journal for parasitology
Bourke CD,Prendergast CT,Sanin DE,Oulton TE,Hall RJ,Mountford AP
25-0451 was used in Flow cytometry/Cell sorting to indicate that S.mansoni cercariae and their excretory/secretory products act directly upon epidermal keratinocytes.
Sun Mar 01 00:00:00 EST 2015
Conditional immortalization of primary adipocyte precursor cells.
Adipocyte
Church C,Brown M,Rodeheffer MS
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Aug 10 00:00:00 EDT 2015
Extraocular muscle satellite cells are high performance myo-engines retaining efficient regenerative capacity in dystrophin deficiency.
Developmental biology
Stuelsatz P,Shearer A,Li Y,Muir LA,Ieronimakis N,Shen QW,Kirillova I,Yablonka-Reuveni Z
25-0451 was used in Flow cytometry/Cell sorting to characterise extraocular muscle cells and assess their potential as a cell-based therapy to combat skeletal muscle wasting.
Thu Jan 01 00:00:00 EST 2015
Nonadherent culture method downregulates stem cell antigen-1 expression in mouse bone marrow mesenchymal stem cells.
Experimental and therapeutic medicine
Deng B,Deng W,Xiao P,Zeng K,Zhang S,Zhang H,Deng DY,Yang Y
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2015
Numb is required to prevent p53-dependent senescence following skeletal muscle injury.
Nature communications
Le Roux I,Konge J,Le Cam L,Flamant P,Tajbakhsh S
25-0451 was used in Flow cytometry/Cell sorting to provide insights into the mechanisms regulating senescence in regenerating muscle.
Tue Oct 27 00:00:00 EDT 2015
Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors.
PloS one
Tähtinen S,Kaikkonen S,Merisalo-Soikkeli M,Grönberg-Vähä-Koskela S,Kanerva A,Parviainen S,Vähä-Koskela M,Hemminki A
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Apr 28 00:00:00 EDT 2016
The NLRP3 inflammasome is critically involved in the development of bronchopulmonary dysplasia.
Nature communications
Liao J,Kapadia VS,Brown LS,Cheong N,Longoria C,Mija D,Ramgopal M,Mirpuri J,McCurnin DC,Savani RC
25-0451 was used in Flow cytometry/Cell sorting to monitor the ratio of IL1β:IL1ra within tracheal aspirates from preterm infants during the development of bronchopulmonary dysplasia.
Fri Nov 27 00:00:00 EST 2015
Distinct in vitro properties of embryonic and extraembryonic fibroblast-like cells are reflected in their in vivo behavior following grafting in the adult mouse brain.
Cell transplantation
Costa R,Bergwerf I,Santermans E,De Vocht N,Praet J,Daans J,Le Blon D,Hoornaert C,Reekmans K,Hens N,Goossens H,Berneman Z,Parolini O,Alviano F,Ponsaerts P
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Nov 16 00:00:00 EST 2015
The Nuclear Orphan Receptor NR2F6 Is a Central Checkpoint for Cancer Immune Surveillance.
Cell reports
Hermann-Kleiter N,Klepsch V,Wallner S,Siegmund K,Klepsch S,Tuzlak S,Villunger A,Kaminski S,Pfeifhofer-Obermair C,Gruber T,Wolf D,Baier G
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Sep 29 00:00:00 EDT 2015
Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1.
PloS one
Szulzewsky F,Pelz A,Feng X,Synowitz M,Markovic D,Langmann T,Holtman IR,Wang X,Eggen BJ,Boddeke HW,Hambardzumyan D,Wolf SA,Kettenmann H
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2016
Targeted Gene Correction in Osteopetrotic-Induced Pluripotent Stem Cells for the Generation of Functional Osteoclasts.
Stem cell reports
Neri T,Muggeo S,Paulis M,Caldana ME,Crisafulli L,Strina D,Focarelli ML,Faggioli F,Recordati C,Scaramuzza S,Scanziani E,Mantero S,Buracchi C,Sobacchi C,Lombardo A,Naldini L,Vezzoni P,Villa A,Ficara F
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Oct 13 00:00:00 EDT 2015
Cardiac telocytes and fibroblasts in primary culture: different morphologies and immunophenotypes.
PloS one
Bei Y,Zhou Q,Fu S,Lv D,Chen P,Chen Y,Wang F,Xiao J
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed Nov 11 00:00:00 EST 2015
Galectin-3 deficiency exacerbates hyperglycemia and the endothelial response to diabetes.
Cardiovascular diabetology
Darrow AL,Shohet RV
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Sat Jun 06 00:00:00 EDT 2015
Endothelial Gata5 transcription factor regulates blood pressure.
Nature communications
Messaoudi S,He Y,Gutsol A,Wight A,Hébert RL,Vilmundarson RO,Makrigiannis AP,Chalmers J,Hamet P,Tremblay J,McPherson R,Stewart AFR,Touyz RM,Nemer M
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Nov 30 00:00:00 EST 2015
Fibrocyte-like cells mediate acquired resistance to anti-angiogenic therapy with bevacizumab.
Nature communications
Mitsuhashi A,Goto H,Saijo A,Trung VT,Aono Y,Ogino H,Kuramoto T,Tabata S,Uehara H,Izumi K,Yoshida M,Kobayashi H,Takahashi H,Gotoh M,Kakiuchi S,Hanibuchi M,Yano S,Yokomise H,Sakiyama S,Nishioka Y
25-0451 was used in Flow cytometry/Cell sorting to show that bone marrow-derived fibrocyte-like cells contribute to the acquired resistance to anti-angiogenic therapy with bevacizumab.
Fri Dec 04 00:00:00 EST 2015
Reprogramming human endothelial cells to haematopoietic cells requires vascular induction.
Nature
Sandler VM,Lis R,Liu Y,Kedem A,James D,Elemento O,Butler JM,Scandura JM,Rafii S
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Jul 17 00:00:00 EDT 2014
Reprogramming human endothelial cells to haematopoietic cells requires vascular induction.
Nature
Sandler VM,Lis R,Liu Y,Kedem A,James D,Elemento O,Butler JM,Scandura JM,Rafii S
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Jul 17 00:00:00 EDT 2014
Reprogramming human endothelial cells to haematopoietic cells requires vascular induction.
Nature
Sandler VM,Lis R,Liu Y,Kedem A,James D,Elemento O,Butler JM,Scandura JM,Rafii S
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Jul 17 00:00:00 EDT 2014
Co-targeting of convergent nucleotide biosynthetic pathways for leukemia eradication.
The Journal of experimental medicine
Nathanson DA,Armijo AL,Tom M,Li Z,Dimitrova E,Austin WR,Nomme J,Campbell DO,Ta L,Le TM,Lee JT,Darvish R,Gordin A,Wei L,Liao HI,Wilks M,Martin C,Sadeghi S,Murphy JM,Boulos N,Phelps ME,Faull KF,Herschman HR,Jung ME,Czernin J,Lavie A,Radu CG
25-0451 was used in Flow cytometry/Cell sorting to identify dCTP biosynthesis as a potential new therapeutic target for metabolic interventions in haematological malignancies.
Mon Mar 10 00:00:00 EDT 2014
Co-targeting of convergent nucleotide biosynthetic pathways for leukemia eradication.
The Journal of experimental medicine
Nathanson DA,Armijo AL,Tom M,Li Z,Dimitrova E,Austin WR,Nomme J,Campbell DO,Ta L,Le TM,Lee JT,Darvish R,Gordin A,Wei L,Liao HI,Wilks M,Martin C,Sadeghi S,Murphy JM,Boulos N,Phelps ME,Faull KF,Herschman HR,Jung ME,Czernin J,Lavie A,Radu CG
25-0451 was used in Flow cytometry/Cell sorting to identify dCTP biosynthesis as a potential new therapeutic target for metabolic interventions in haematological malignancies.
Mon Mar 10 00:00:00 EDT 2014
Cell-autonomous heparanase modulates self-renewal and migration in bone marrow-derived mesenchymal stem cells.
Journal of biomedical science
Cheng CC,Lee YH,Lin SP,Huangfu WC,Liu IH
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Mar 13 00:00:00 EDT 2014
Astrocytic transforming growth factor-beta signaling reduces subacute neuroinflammation after stroke in mice.
Glia
Cekanaviciute E,Fathali N,Doyle KP,Williams AM,Han J,Buckwalter MS
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Aug 01 00:00:00 EDT 2014
Blocking junctional adhesion molecule C enhances dendritic cell migration and boosts the immune responses against Leishmania major.
PLoS pathogens
Ballet R,Emre Y,Jemelin S,Charmoy M,Tacchini-Cottier F,Imhof BA
25-0451 was used in Flow cytometry/Cell sorting to illustrate a key role for the vascular adhesion molecule JAM-C in controlling leukocyte migration and subsequent immune events in response to pathogen infections.
Mon Dec 01 00:00:00 EST 2014
Experimental cerebral malaria pathogenesis--hemodynamics at the blood brain barrier.
PLoS pathogens
Nacer A,Movila A,Sohet F,Girgis NM,Gundra UM,Loke P,Daneman R,Frevert U
25-0451 was used in Flow cytometry/Cell sorting to show that significantly more CD8(+) T cells, neutrophils, and macrophages are recruited to postcapillary venules during ECM compared to hyperparasitemia.
Mon Dec 01 00:00:00 EST 2014
Mast cells expedite control of pulmonary murine cytomegalovirus infection by enhancing the recruitment of protective CD8 T cells to the lungs.
PLoS pathogens
Ebert S,Becker M,Lemmermann NA,Büttner JK,Michel A,Taube C,Podlech J,Böhm V,Freitag K,Thomas D,Holtappels R,Reddehase MJ,Stassen M
25-0451 was used in Flow cytometry/Cell sorting to explore the role of mast cells in the recruitment of protective CD8 T cells to the lungs during systemic infection.
Tue Apr 01 00:00:00 EDT 2014
Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing.
Stem cells (Dayton, Ohio)
Suga H,Rennert RC,Rodrigues M,Sorkin M,Glotzbach JP,Januszyk M,Fujiwara T,Longaker MT,Gurtner GC
25-0451 was used in Flow cytometry/Cell sorting to identify cells of haematopoietic origin recruited to the wound site to deposit collagen, confirming the existence of fibrocytes in cutaneous healing.
Thu May 01 00:00:00 EDT 2014
Bone marrow mesenchymal stem cells provide an antibiotic-protective niche for persistent viable Mycobacterium tuberculosis that survive antibiotic treatment.
The American journal of pathology
Beamer G,Major S,Das B,Campos-Neto A
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Dec 01 00:00:00 EST 2014
Identification of hematopoietic-specific regulatory elements from the CD45 gene and use for lentiviral tracking of transplanted cells.
Experimental hematology
Duong KL,Das S,Yu S,Barr JY,Jena S,Kim E,Zavazava N,Colgan JD,Xue HH,Levasseur DN
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Sep 01 00:00:00 EDT 2014
Ancestral Myf5 gene activity in periocular connective tissue identifies a subset of fibro/adipogenic progenitors but does not connote a myogenic origin.
Developmental biology
Stuelsatz P,Shearer A,Yablonka-Reuveni Z
25-0451 was used in Flow cytometry/Cell sorting to identify and characterise the differences between myogenic progenitors (satellite cells) in extraocular muscles to those of the limb and diaphragm of adult mice.
Wed Jan 15 00:00:00 EST 2014
Adipocytes arise from multiple lineages that are heterogeneously and dynamically distributed.
Nature communications
Sanchez-Gurmaches J,Guertin DA
25-0451 was used in Flow cytometry/Cell sorting to establish a framework for adipose tissue development to explain body fat patterning variations in lipodystrophic or obese humans.
Thu Jun 19 00:00:00 EDT 2014
Chronic thoracic spinal cord injury impairs CD8+ T-cell function by up-regulating programmed cell death-1 expression.
Journal of neuroinflammation
Zha J,Smith A,Andreansky S,Bracchi-Ricard V,Bethea JR
25-0451 was used in Flow cytometry/Cell sorting to investigate CD8+ T-cell function by up-regulating programmed cell death-1 expression in chronic thoracic spinal cord injury.
Tue Apr 01 00:00:00 EDT 2014
A new animal model of spontaneous autoimmune peripheral polyneuropathy: implications for Guillain-Barré syndrome.
Acta neuropathologica communications
Yang M,Rainone A,Shi XQ,Fournier S,Zhang J
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed Jan 08 00:00:00 EST 2014
PI3Kδ inhibition reduces TNF secretion and neuroinflammation in a mouse cerebral stroke model.
Nature communications
Low PC,Manzanero S,Mohannak N,Narayana VK,Nguyen TH,Kvaskoff D,Brennan FH,Ruitenberg MJ,Gelderblom M,Magnus T,Kim HA,Broughton BR,Sobey CG,Vanhaesebroeck B,Stow JL,Arumugam TV,Meunier FA
25-0451 was used in Flow cytometry/Cell sorting to show that PI3Kδ inhibition confers protection in ischaemia/reperfusion models of stroke.
Fri Mar 14 00:00:00 EDT 2014
Amniotic fluid stem cells prevent follicle atresia and rescue fertility of mice with premature ovarian failure induced by chemotherapy.
PloS one
Xiao GY,Liu IH,Cheng CC,Chang CC,Lee YH,Cheng WT,Wu SC
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu May 28 00:00:00 EDT 2015
Activation of NLRP3 inflammasome by crystalline structures via cell surface contact.
Scientific reports
Hari A,Zhang Y,Tu Z,Detampel P,Stenner M,Ganguly A,Shi Y
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Dec 02 00:00:00 EST 2014
The nucleotide-binding leucine-rich repeat (NLR) family member NLRX1 mediates protection against experimental autoimmune encephalomyelitis and represses macrophage/microglia-induced inflammation.
The Journal of biological chemistry
Eitas TK,Chou WC,Wen H,Gris D,Robbins GR,Brickey J,Oyama Y,Ting JP
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Feb 14 00:00:00 EST 2014
Notch2 genetic fate mapping reveals two previously unrecognized mammary epithelial lineages.
Nature cell biology
Šale S,Lafkas D,Artavanis-Tsakonas S
25-0451 was used in Flow cytometry/Cell sorting to study the fate of cells expressing the Notch2 receptor paralogue, uncovering two novel mammary epithelial cell linages.
Wed May 01 00:00:00 EDT 2013
Mesenchymal stem cells are mobilized from the bone marrow during inflammation.
Frontiers in immunology
Koning JJ,Kooij G,de Vries HE,Nolte MA,Mebius RE
25-0451 was used in Flow cytometry/Cell sorting to analyse mesenchymal stem- and T-cell migration during experimental allergic encephalomyelitis.
Wed Mar 06 00:00:00 EST 2013
Evidence for a multipotent mammary progenitor with pregnancy-specific activity.
Breast cancer research : BCR
Kaanta AS,Virtanen C,Selfors LM,Brugge JS,Neel BG
25-0451 was used in Flow cytometry/Cell sorting to provide data to show the existence of multi-potent mammary progenitor cells that have pregnancy-specific function.
Mon Dec 08 00:00:00 EST 2014
Efficiently stimulated adult microglia cross-prime naive CD8+ T cells injected in the brain.
European journal of immunology
Jarry U,Jeannin P,Pineau L,Donnou S,Delneste Y,Couez D
25-0451 was used in Flow cytometry/Cell sorting to study whether microglia are able to cross-present antigen to naive CD8(+) T cells within the brain microenvironment in vivo.
Wed May 01 00:00:00 EDT 2013
Kupffer cells potentiate liver sinusoidal endothelial cell injury in sepsis by ligating programmed cell death ligand-1.
Journal of leukocyte biology
Hutchins NA,Wang F,Wang Y,Chung CS,Ayala A
25-0451 was used in Flow cytometry/Cell sorting to study Kupffer cell-mediated potentiation of liver sinusoidal endothelial cell injury in sepsis by ligating programmed cell death ligand-1.
Fri Nov 01 00:00:00 EDT 2013
Ectopic Runx1 expression rescues Tal-1-deficiency in the generation of primitive and definitive hematopoiesis.
PloS one
Tornack J,Seiler K,Grützkau A,Grün JR,Onodera M,Melchers F,Tsuneto M
25-0451 was used in Flow cytometry/Cell sorting to suggest that Tal-1 expression is needed to express Runx1 in the mesoderm.
Thu Aug 21 00:00:00 EDT 2014
Gli1 deletion prevents Helicobacter-induced gastric metaplasia and expansion of myeloid cell subsets.
PloS one
El-Zaatari M,Kao JY,Tessier A,Bai L,Hayes MM,Fontaine C,Eaton KA,Merchant JL
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Sep 10 00:00:00 EDT 2013
Tumorigenic cells are common in mouse MPNSTs but their frequency depends upon tumor genotype and assay conditions.
Cancer cell
Buchstaller J,McKeever PE,Morrison SJ
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Feb 14 00:00:00 EST 2012
Nucleoside salvage pathway kinases regulate hematopoiesis by linking nucleotide metabolism with replication stress.
The Journal of experimental medicine
Austin WR,Armijo AL,Campbell DO,Singh AS,Hsieh T,Nathanson D,Herschman HR,Phelps ME,Witte ON,Czernin J,Radu CG
25-0451 was used in Flow cytometry/Cell sorting to investigate a functional link between nucleotide deficiency, replication stress, and two enzymes of the nucleoside salvage pathway: deoxycytidine kinase and thymidine kinase.
Mon Nov 19 00:00:00 EST 2012
ALDH1A isozymes are markers of human melanoma stem cells and potential therapeutic targets.
Stem cells (Dayton, Ohio)
Luo Y,Dallaglio K,Chen Y,Robinson WA,Robinson SE,McCarter MD,Wang J,Gonzalez R,Thompson DC,Norris DA,Roop DR,Vasiliou V,Fujita M
25-0451 was used in Flow cytometry/Cell sorting to demonstrate the existence of melanoma cells that fulfil the criteria for CSCs.
Mon Oct 01 00:00:00 EDT 2012
Etv2 is expressed in the yolk sac hematopoietic and endothelial progenitors and regulates Lmo2 gene expression.
Stem cells (Dayton, Ohio)
Koyano-Nakagawa N,Kweon J,Iacovino M,Shi X,Rasmussen TL,Borges L,Zirbes KM,Li T,Perlingeiro RC,Kyba M,Garry DJ
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Wed Aug 01 00:00:00 EDT 2012
A model of GAG/MIP-2/CXCR2 interfaces and its functional effects.
Biochemistry
Rajasekaran D,Keeler C,Syed MA,Jones MC,Harrison JK,Wu D,Bhandari V,Hodsdon ME,Lolis EJ
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Jul 17 00:00:00 EDT 2012
Origins and properties of dental, thymic, and bone marrow mesenchymal cells and their stem cells.
PloS one
Komada Y,Yamane T,Kadota D,Isono K,Takakura N,Hayashi S,Yamazaki H
25-0451 was used in Flow cytometry/Cell sorting to investigate whether mesechymal cells arise from neural crest or mesoderm, revealing the origins and properties of dental, thymic, and bone marrow mesenchymal cells.
Tue May 14 00:00:00 EDT 2013
Delta-like ligand (DLL)1 expression in early mouse decidua and its localization to uterine natural killer cells.
PloS one
Degaki KY,Chen Z,Yamada AT,Croy BA
25-0451 was used in Immunohistochemistry to suggest that uNK cells may induce endothelial tip cell differentiation and promote non-planar vascular growth within early decidua basalis.
Tue Jun 25 00:00:00 EDT 2013
Cell type-associated differences in migration, survival, and immunogenicity following grafting in CNS tissue.
Cell transplantation
Praet J,Reekmans K,Lin D,De Vocht N,Bergwerf I,Tambuyzer B,Daans J,Hens N,Goossens H,Pauwels P,Berneman Z,Van der Linden A,Ponsaerts P
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Dec 06 00:00:00 EST 2013
A method for quantifying pulmonary Legionella pneumophila infection in mouse lungs by flow cytometry.
BMC research notes
Ang DK,Ong SY,Brown AS,Hartland EL,van Driel IR
25-0451 was used in Flow cytometry/Cell sorting to describe a novel, rapid and versatile method that detects bacteria phagocytosed by neutrophils.
Mon Aug 20 00:00:00 EDT 2012
ER71 directs mesodermal fate decisions during embryogenesis.
Development (Cambridge, England)
Rasmussen TL,Kweon J,Diekmann MA,Belema-Bedada F,Song Q,Bowlin K,Shi X,Ferdous A,Li T,Kyba M,Metzger JM,Koyano-Nakagawa N,Garry DJ
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2011
Expression of retinaldehyde dehydrogenase enzymes in mucosal dendritic cells and gut-draining lymph node stromal cells is controlled by dietary vitamin A.
Journal of immunology (Baltimore, Md. : 1950)
Molenaar R,Knippenberg M,Goverse G,Olivier BJ,de Vos AF,O'Toole T,Mebius RE
25-0451 was used in Magnetic cell separation to show that during postnatal development, dietary vitamin A is essential for the induction of retinaldehyde dehydrogenases in mucosal DCs and MLN stromal cells.
Tue Feb 15 00:00:00 EST 2011
Clonal analysis reveals uniformity in the molecular profile and lineage potential of CCR9(+) and CCR9(-) thymus-settling progenitors.
Journal of immunology (Baltimore, Md. : 1950)
Desanti GE,Jenkinson WE,Parnell SM,Boudil A,Gautreau-Rolland L,Eksteen B,Ezine S,Lane PJ,Jenkinson EJ,Anderson G
25-0451 was used in Flow cytometry/Cell sorting to suggest that the earliest T cell progenitors represent a developmentally homogeneous progenitor pool that ensures the efficient generation of the first cohorts of T cells during thymus development.
Sun May 01 00:00:00 EDT 2011
Effect of topical azithromycin on corneal innate immune responses.
Investigative ophthalmology & visual science
Sadrai Z,Hajrasouliha AR,Chauhan S,Saban DR,Dastjerdi MH,Dana R
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Tue Apr 19 00:00:00 EDT 2011
Topical imiquimod has therapeutic and immunomodulatory effects against intracranial tumors.
Journal of immunotherapy (Hagerstown, Md. : 1997)
Xiong Z,Ohlfest JR
25-0451 was used in Flow cytometry/Cell sorting to demonstrate that topical application of the TLR7 agonist imiquimod can enhance T-cell responses to intracranial tumors as a single agent in mice.
Fri Apr 01 00:00:00 EDT 2011
Myeloid cells migrate in response to IL-24.
Cytokine
Buzas K,Oppenheim JJ,Zack Howard OM
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2011
Clinical potential of intravenous neural stem cell delivery for treatment of neuroinflammatory disease in mice?
Cell transplantation
Reekmans KP,Praet J,De Vocht N,Tambuyzer BR,Bergwerf I,Daans J,Baekelandt V,Vanhoutte G,Goossens H,Jorens PG,Ysebaert DK,Chatterjee S,Pauwels P,Van Marck E,Berneman ZN,Van der Linden A,Ponsaerts P
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Fri Dec 09 00:00:00 EST 2011
Lymphotoxin beta receptor signaling promotes tertiary lymphoid organogenesis in the aorta adventitia of aged ApoE-/- mice.
The Journal of experimental medicine
Gräbner R,Lötzer K,Döpping S,Hildner M,Radke D,Beer M,Spanbroek R,Lippert B,Reardon CA,Getz GS,Fu YX,Hehlgans T,Mebius RE,van der Wall M,Kruspe D,Englert C,Lovas A,Hu D,Randolph GJ,Weih F,Habenicht AJ
25-0451 was used in Flow cytometry/Cell sorting to investigate how the LTbetaR pathway has a major role in shaping the immunological characteristics and overall integrity of the arterial wall.
Fri Jan 16 00:00:00 EST 2009
The survival of memory CD4+ T cells within the gut lamina propria requires OX40 and CD30 signals.
Journal of immunology (Baltimore, Md. : 1950)
Withers DR,Jaensson E,Gaspal F,McConnell FM,Eksteen B,Anderson G,Agace WW,Lane PJL
25-0451 was used in Flow cytometry/Cell sorting to investigate how signals through CD30 and OX40 may be required for the survival of CD4+ T cells within the gut lamina propria.
Thu Oct 15 00:00:00 EDT 2009
Optimized isolation enables ex vivo analysis of microglia from various central nervous system regions.
Glia
de Haas AH,Boddeke HW,Brouwer N,Biber K
Published figure using CD45 monoclonal antibody (Product # 25-0451-82) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2007
