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Invitrogen
CD52 Chimeric Recombinant Mouse Monoclonal Antibody (YTH 34.5-G2b (Campath-1G))
Product Details
MA5-47806
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Cynomolgus monkey,
Human,
Rhesus monkey
Host/Isotype
Mouse
/ IgG1, kappa
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
YTH 34.5-G2b (Campath-1G)
Immunogen
Human peripheral mononuclear cells enriched for T-cells.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.02% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_3074254
Product Specific Information
Specificity: Human CD52 antigen, also known as CAMPATH-1. CD52 is expressed at high density by lymphocytes, monocytes, eosinophils, thymocytes and macrophages. It is expressed by most lymphoid derived malignancies, although expression on myeloma cells is variable.
Target Information
CD52, also known as CAMPATH-1 antigen, is a glycoprotein that is expressed on the surface of various immune cells, including T and B lymphocytes, natural killer cells, and monocytes. It is involved in the regulation of immune responses and is being studied as a potential therapeutic target in various diseases, including multiple sclerosis, chronic lymphocytic leukemia, and autoimmune disorders. CD52 is the target of alemtuzumab, a monoclonal antibody that is used to treat these conditions by depleting immune cells that express CD52.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cambridge pathology 1 antigen; CAMPATH-1 antigen; CD52; CD52 antigen; CD52 antigen (CAMPATH-1 antigen); CDw52; CDW52 antigen (CAMPATH-1 antigen); epididymal CAMPATH-1 antigen,epididymal CDw52 antigen; Epididymal secretory protein E5; epididymis secretory sperm binding protein Li 171mP; He5; HEL-S-171mP; Human epididymis-specific protein 5
Gene Aliases: CD52; CDW52; EGK_00417; HE5
UniProt ID: (Human) P31358, (Cynomolgus monkey) P32763
Entrez Gene ID: (Human) 1043, (Rhesus monkey) 714429, (Cynomolgus monkey) 102144354
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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