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Invitrogen
CD90 Recombinant Rabbit Monoclonal Antibody (HL1766)
FIGURE: 1 / 4
CD90 Antibody (MA5-47174) in ICC/IF
Immunofluorescent analysis of CD90 in DIV9 rat E18 primary cortical neuron cells. Cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: CD90 stained by CD90 monoclonal antibody (Product # MA5-47174) diluted at 1:250. Red: Tau, an Axon marker, stained by Tau antibody [GT287] diluted at 1:500. Blue: Fluoroshield with DAPI.
Product Details
MA5-47174
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HL1766
Immunogen
Recombinant protein encompassing a sequence within the center region of human CD90. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2938246
Product Specific Information
Store as concentrated solution.
Centrifuge briefly prior to opening vial.
Target Information
CD90 (Thy 1) antigen is a GPI linked glycoprotein member of the Immunoglobulin super family. CD90 is expressed in murine T cells, thymocytes, neural cells, Kupffer's cells and fibroblasts. CD90 may play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. CD90 can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons. Structural study of CD90 led to the foundation of the Immunoglobulin superfamily, of which it is the smallest member, and led to the first biochemical description and characterization of a vertebrate GPI anchor. Diseases associated with CD90 dysfunction include nasopharyngeal carcinoma and thymoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD90; CDw90; FLJ33325; Thy 1.2; Thy-1 antigen; thy-1 glycoprotein; Thy-1 membrane glycoprotein; Thy-1 protein; Thy-1 T-cell antigen; thymus cell antigen 1, theta; Thymus cell surface antigen
Gene Aliases: CD7; CD90; CDw90; T25; Thy-1; Thy-1.2; THY1; Thy1.1; Thy1.2
UniProt ID: (Human) P04216, (Mouse) P01831, (Rat) P01830
Entrez Gene ID: (Human) 7070, (Mouse) 21838, (Rat) 24832
angiogenesis
negative regulation of protein kinase activity
cytoskeleton organization
single organismal cell-cell adhesion
negative regulation of cell migration
positive regulation of GTPase activity
retinal cone cell development
protein autophosphorylation
focal adhesion assembly
negative regulation of axonogenesis
T cell receptor signaling pathway
negative regulation of T cell receptor signaling pathway
positive regulation of T cell activation
positive regulation of release of sequestered calcium ion into cytosol
negative regulation of apoptotic process
mast cell activation
negative regulation of fibroblast proliferation
positive regulation of peptidyl-tyrosine phosphorylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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