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Invitrogen
CD98 Chimeric Recombinant Rabbit Monoclonal Antibody (RL388)
FIGURE: 1 / 2
CD98 Chimeric Antibody (MA5-48210) in ICC/IF
Immunocytochemistry/Immunofluorescence analysis of CD98 in mouse splenocytes using CD98 Chimeric Monoclonal Antibody (Product # MA5-48210). Paraformaldehyde-fixed cells were immobilized on cover slips and stained with CD98 Chimeric Monoclonal Antibody at 10 µg/mL followed by Alexa Fluor 488 secondary antibody (2 µg/mL), showing membrane staining. The nuclear stain is DAPI (blue). Panels show from left-right... View More
Product Details
MA5-48210
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG, kappa
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
RL388
Immunogen
This antibody was raised by immunising rats with an IL 2-producing subline of the mouse T lymphoma EL4.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.02% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_3074653
Product Specific Information
Specificity: This antibody recognises murine CD98, a heterodimeric cell surface glycoprotein.
Target Information
CD98 (4F2) is a type II transmembrane glycoprotein which serves as the heavy chain of the heterodimeric amino acid transporters (HATs). CD98, linked to various light chains by disulfide bond, is responsible for cell surface expression and basolateral localization of this transporter complex in polarized epithelial cells and also interacts with beta1 integrins and increases their affinity for ligand. Besides its roles in amino acid transport, CD98 is thus involved in cell fusion and activation. It is implicated in regulation of cellular differentiation, growth and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 4F2 cell-surface antigen heavy chain; 4F2hc; Amino acid transporter heavy chain SLC3A2; antigen identified by monoclonal antibodies 4F2; CD98; CD98 antigen; CD98 heavy chain; Solute carrier family 3 member 2; type II transmembrane protein
Gene Aliases: 4F2; 4F2HC; AI314110; Cd98; Ly-10; Ly-m10; Ly10; Mdu1; Mgp-2hc; NACAE; Slc3a2
UniProt ID: (Mouse) P10852
Entrez Gene ID: (Mouse) 17254
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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