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Recommended positive controls: A431, HeLa, mouse kidney.
Predicted reactivity: Mouse (86%), Rat (86%), Pig (87%), Bovine (86%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cytidine aminohydrolase; Cytidine deaminase; cytosine nucleoside deaminase; EC 3.5.4.5; small cytidine deaminase
Gene Aliases: 2210401N16Rik; CDA; CDD
UniProt ID: (Human) P32320, (Mouse) P56389
Entrez Gene ID: (Human) 978, (Mouse) 72269
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