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The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.
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Protein Aliases: Anaphase-promoting complex subunit 6; anaphase-promoting complex, subunit 6; APC6; CDC16 cell division cycle 16 homolog; CDC16 homolog; CDC16Hs; cell division cycle 16 homolog; Cell division cycle protein 16 homolog; Cyclosome subunit 6; RP11-569D9.4
Gene Aliases: 2700071J12Rik; 2810431D22Rik; ANAPC6; APC6; CDC16; CDC16Hs; CUT9
UniProt ID: (Human) Q7Z651, (Mouse) Q8R349
Entrez Gene ID: (Human) 8881, (Rat) 290875, (Mouse) 69957
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