Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Immunogen sequence: NSHVVYQLLS PEPEDGVEGR AFQVDPTSGS VTLGVLPLRA GQNILLLVLA MDLAGAEGGF SSTCEVEVAV TDINDHAPEF ITSQIGPISL PEDVEPGTLV AMLTAIDADL EPAFRLMDFA IERGDTEGTF GLDWEPDS
Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 76%.
The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. Cadherin-16, also known as Ksp-Cadherin, is a type I membrane protein which is kidney-specific. Cadherin-16 is expressed exclusively in the basolateral membrane of renal tubular epithelial cells. The human Ksp-cadherin gene (Cadherin-16) maps to chromosome 16q21-proximal 16q22. The mouse Ksp-cadherin gene was localized to a highly syntenic region of distal Chromosome 8.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cadherin; cadherin 16, KSP-cadherin; Cadherin-16; Cadherin-16 (CDH16); CDH 16; Kidney-specific cadherin; KSP-cadherin; Ksp-cadherin antibody
Gene Aliases: CDH16; UNQ695/PRO1340
UniProt ID: (Human) O75309
Entrez Gene ID: (Human) 1014
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